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Items: 1 to 50 of 283

1.

Depth Map Upsampling via Multi-Modal Generative Adversarial Network.

Tan DS, Lin JM, Lai YC, Ilao J, Hua KL.

Sensors (Basel). 2019 Apr 2;19(7). pii: E1587. doi: 10.3390/s19071587.

2.

Targeting adenylate-forming enzymes with designed sulfonyladenosine inhibitors.

Lux MC, Standke LC, Tan DS.

J Antibiot (Tokyo). 2019 Apr 15. doi: 10.1038/s41429-019-0171-2. [Epub ahead of print] Review.

PMID:
30982830
3.

Sex Differences in 1-Year Rehospitalization for Heart Failure and Myocardial Infarction After Primary Percutaneous Coronary Intervention.

Zheng H, Foo LL, Tan HC, Richards AM, Chan SP, Lee CH, Low AFH, Hausenloy DJ, Tan JWC, Sahlen AO, Ho HH, Chai SC, Tong KL, Tan DSY, Yeo KK, Chua TSJ, Lam CSP, Chan MY.

Am J Cardiol. 2019 Mar 19. pii: S0002-9149(19)30318-2. doi: 10.1016/j.amjcard.2019.03.021. [Epub ahead of print]

PMID:
30979413
4.

Single-Image Depth Inference Using Generative Adversarial Networks.

Tan DS, Yao CY, Ruiz C Jr, Hua KL.

Sensors (Basel). 2019 Apr 10;19(7). pii: E1708. doi: 10.3390/s19071708.

5.

Third generation EGFR TKI landscape for metastatic EGFR mutant non-small cell lung cancer (NSCLC).

Tan AC, Teh YL, Lai GGY, Tan DSW.

Expert Rev Anticancer Ther. 2019 Apr 5:1-5. doi: 10.1080/14737140.2019.1604228. [Epub ahead of print] No abstract available.

PMID:
30950666
6.

Structure-Based Design, Synthesis, and Biological Evaluation of Non-Acyl Sulfamate Inhibitors of the Adenylate-Forming Enzyme MenE.

Evans CE, Si Y, Matarlo JS, Yin Y, French JB, Tonge PJ, Tan DS.

Biochemistry. 2019 Apr 9;58(14):1918-1930. doi: 10.1021/acs.biochem.9b00003. Epub 2019 Mar 26.

PMID:
30912442
7.

Mutational Aberrations Detected in Mucinous Epithelial Ovarian Cancer of Asian Women.

Chay WY, Kwok LL, Tiong WN, Krisna SS, Lim KH, Iyer NG, Goh LK, Tan DS.

Int J Gynecol Cancer. 2018 Mar;28(3):428-436. doi: 10.1097/IGC.0000000000001138.

PMID:
30814206
8.

25OUse of CTTA to predict treatment response in patients with EGFR T790M+ NSCLC treated with osimertinib.

Tan WL, Tran Nguyen TA, Koh TS, Priyanthi Hennedige T, Yip CSP, Tan SH, Tan DSW, Thng CH, Lim DW, Ng QS.

Ann Oncol. 2019 Feb 1;30(Supplement_1). pii: mdz030. doi: 10.1093/annonc/mdz030. No abstract available.

PMID:
30810206
9.

The 4th European Society for Medical Oncology Asia Congress: bridging ultimate cancer care with real-world practice for the Asian practitioner in gynecological cancers.

Ngoi NY, Tan DS.

J Gynecol Oncol. 2019 Mar;30(2):e48. doi: 10.3802/jgo.2019.30.e48. Epub 2019 Jan 11. No abstract available.

10.

Asian Society of Gynecologic Oncology International Workshop 2018.

Kong TW, Ryu HS, Kim SC, Enomoto T, Li J, Kim KH, Shim SH, Wang PH, Therasakvichya S, Kobayashi Y, Lee M, Shi T, Lee SW, Mikami M, Nagase S, Lim MC, Wang J, Wilailak S, Kim SW, Hong SH, Tan DS, Mandai M, Chang SJ, Huang RYJ, Ushijima K, Lee JY, Chen X, Ochiai K, Lee TS, Yang B, Kalam F, Lv Q, Ahmad MF, Yaznil MR, Modi KB, Manopunya M, Jeong DH, Lertkhachonsuk AA, Chung HH, Watari H, Jeon S.

J Gynecol Oncol. 2019 Mar;30(2):e39. doi: 10.3802/jgo.2019.30.e39. Epub 2019 Jan 14. Review.

11.

Validation of the Chinese Manchester foot pain and disability index (C-MFPDI) among patients with inflammatory arthritis.

Erh BXY, He HG, Carter KF, Cheung PP, Tan DS, Wang W, Rome K.

J Foot Ankle Res. 2019 Jan 23;12:6. doi: 10.1186/s13047-019-0316-3. eCollection 2019.

12.

Clonal MET Amplification as a Determinant of Tyrosine Kinase Inhibitor Resistance in Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer.

Lai GGY, Lim TH, Lim J, Liew PJR, Kwang XL, Nahar R, Aung ZW, Takano A, Lee YY, Lau DPX, Tan GS, Tan SH, Tan WL, Ang MK, Toh CK, Tan BS, Devanand A, Too CW, Gogna A, Ong BH, Koh TPT, Kanesvaran R, Ng QS, Jain A, Rajasekaran T, Yuan J, Lim TKH, Lim AST, Hillmer AM, Lim WT, Iyer NG, Tam WL, Zhai W, Tan EH, Tan DSW.

J Clin Oncol. 2019 Apr 10;37(11):876-884. doi: 10.1200/JCO.18.00177. Epub 2019 Jan 24.

PMID:
30676858
13.

Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.

Kearney SE, Zahoránszky-Kőhalmi G, Brimacombe KR, Henderson MJ, Lynch C, Zhao T, Wan KK, Itkin Z, Dillon C, Shen M, Cheff DM, Lee TD, Bougie D, Cheng K, Coussens NP, Dorjsuren D, Eastman RT, Huang R, Iannotti MJ, Karavadhi S, Klumpp-Thomas C, Roth JS, Sakamuru S, Sun W, Titus SA, Yasgar A, Zhang YQ, Zhao J, Andrade RB, Brown MK, Burns NZ, Cha JK, Mevers EE, Clardy J, Clement JA, Crooks PA, Cuny GD, Ganor J, Moreno J, Morrill LA, Picazo E, Susick RB, Garg NK, Goess BC, Grossman RB, Hughes CC, Johnston JN, Joullie MM, Kinghorn AD, Kingston DGI, Krische MJ, Kwon O, Maimone TJ, Majumdar S, Maloney KN, Mohamed E, Murphy BT, Nagorny P, Olson DE, Overman LE, Brown LE, Snyder JK, Porco JA Jr, Rivas F, Ross SA, Sarpong R, Sharma I, Shaw JT, Xu Z, Shen B, Shi W, Stephenson CRJ, Verano AL, Tan DS, Tang Y, Taylor RE, Thomson RJ, Vosburg DA, Wu J, Wuest WM, Zakarian A, Zhang Y, Ren T, Zuo Z, Inglese J, Michael S, Simeonov A, Zheng W, Shinn P, Jadhav A, Boxer MB, Hall MD, Xia M, Guha R, Rohde JM.

ACS Cent Sci. 2018 Dec 26;4(12):1727-1741. doi: 10.1021/acscentsci.8b00747. Epub 2018 Dec 5.

14.

Pan-Asian adapted Clinical Practice Guidelines for the management of patients with metastatic non-small-cell lung cancer: a CSCO-ESMO initiative endorsed by JSMO, KSMO, MOS, SSO and TOS.

Wu YL, Planchard D, Lu S, Sun H, Yamamoto N, Kim DW, Tan DSW, Yang JC, Azrif M, Mitsudomi T, Park K, Soo RA, Chang JWC, Alip A, Peters S, Douillard JY.

Ann Oncol. 2019 Feb 1;30(2):171-210. doi: 10.1093/annonc/mdy554.

PMID:
30596843
15.

Efficacy and safety of reduced-dose non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation: a meta-analysis of randomized controlled trials.

Wang KL, Lopes RD, Patel MR, Büller HR, Tan DS, Chiang CE, Giugliano RP.

Eur Heart J. 2018 Dec 22. doi: 10.1093/eurheartj/ehy802. [Epub ahead of print]

PMID:
30590440
16.

Correction to: Influence of afatinib dose on outcomes of advanced EGFR-mutant NSCLC patients with brain metastases.

Tan WL, Ng QS, Lim C, Tan EH, Toh CK, Ang MK, Kanesvaran R, Jain A, Tan DSW, Lim DW.

BMC Cancer. 2018 Dec 24;18(1):1288. doi: 10.1186/s12885-018-5215-7.

17.

Kinetic Analyses of the Siderophore Biosynthesis Inhibitor Salicyl-AMS and Analogues as MbtA Inhibitors and Antimycobacterial Agents.

Bythrow GV, Mohandas P, Guney T, Standke LC, Germain GA, Lu X, Ji C, Levendosky K, Chavadi SS, Tan DS, Quadri LEN.

Biochemistry. 2019 Feb 12;58(6):833-847. doi: 10.1021/acs.biochem.8b01153. Epub 2019 Jan 10.

PMID:
30582694
18.

Concurrent Single-Cell RNA and Targeted DNA Sequencing on an Automated Platform for Comeasurement of Genomic and Transcriptomic Signatures.

Kong SL, Li H, Tai JA, Courtois ET, Poh HM, Lau DP, Haw YX, Iyer NG, Tan DSW, Prabhakar S, Ruff D, Hillmer AM.

Clin Chem. 2019 Feb;65(2):272-281. doi: 10.1373/clinchem.2018.295717. Epub 2018 Dec 6.

PMID:
30523199
19.

Influence of afatinib dose on outcomes of advanced EGFR-mutant NSCLC patients with brain metastases.

Tan WL, Ng QS, Lim C, Tan EH, Toh CK, Ang MK, Kanesvaran R, Jain A, Tan DSW, Lim DW.

BMC Cancer. 2018 Dec 3;18(1):1198. doi: 10.1186/s12885-018-5110-2. Erratum in: BMC Cancer. 2018 Dec 24;18(1):1288.

20.

Effects of Single Nucleotide Polymorphisms on the Binding of Afatinib to EGFR: A Potential Patient Stratification Factor Revealed by Modeling Studies.

Kannan S, Tan DS, Verma CS.

J Chem Inf Model. 2019 Jan 28;59(1):309-315. doi: 10.1021/acs.jcim.8b00491. Epub 2018 Dec 10.

PMID:
30481018
21.

Synthesis of the hexacyclic triterpene core of the jujuboside saponins via tandem Wolff rearrangement-intramolecular ketene hetero-Diels-Alder reaction.

Karimov RR, Tan DS, Gin DY.

Tetrahedron. 2018 Jun 28;74(26):3370-3383. doi: 10.1016/j.tet.2018.04.051. Epub 2018 Apr 19.

PMID:
30467444
22.

Decoding transcriptomic intra-tumour heterogeneity to guide personalised medicine in ovarian cancer.

Tan TZ, Heong V, Ye J, Lim D, Low J, Choolani M, Scott C, Tan DSP, Huang RY.

J Pathol. 2019 Mar;247(3):305-319. doi: 10.1002/path.5191. Epub 2018 Dec 18.

PMID:
30374975
23.
24.

Phase Ib/II Study of Capmatinib (INC280) Plus Gefitinib After Failure of Epidermal Growth Factor Receptor (EGFR) Inhibitor Therapy in Patients With EGFR-Mutated, MET Factor-Dysregulated Non-Small-Cell Lung Cancer.

Wu YL, Zhang L, Kim DW, Liu X, Lee DH, Yang JC, Ahn MJ, Vansteenkiste JF, Su WC, Felip E, Chia V, Glaser S, Pultar P, Zhao S, Peng B, Akimov M, Tan DSW.

J Clin Oncol. 2018 Nov 1;36(31):3101-3109. doi: 10.1200/JCO.2018.77.7326. Epub 2018 Aug 29. Erratum in: J Clin Oncol. 2019 Jan 20;37(3):261.

PMID:
30156984
25.

Comparison of rivaroxaban concentrations between Asians and Caucasians and their correlation with PT/INR.

Ng Tsai HO, Goh JJN, Aw JWX, Lin Y, Fong AYY, Tiong LL, Tan DS.

J Thromb Thrombolysis. 2018 Nov;46(4):541-548. doi: 10.1007/s11239-018-1726-y.

PMID:
30155672
26.

Anti-tumor efficacy of Selinexor (KPT-330) in gastric cancer is dependent on nuclear accumulation of p53 tumor suppressor.

Subhash VV, Yeo MS, Wang L, Tan SH, Wong FY, Thuya WL, Tan WL, Peethala PC, Soe MY, Tan DSP, Padmanabhan N, Baloglu E, Shacham S, Tan P, Koeffler HP, Yong WP.

Sci Rep. 2018 Aug 16;8(1):12248. doi: 10.1038/s41598-018-30686-1.

27.

A Clinical and Molecular Phase II Trial of Oral ENMD-2076 in Ovarian Clear Cell Carcinoma (OCCC): A Study of the Princess Margaret Phase II Consortium.

Lheureux S, Tinker A, Clarke B, Ghatage P, Welch S, Weberpals JI, Dhani NC, Butler MO, Tonkin K, Tan Q, Tan DSP, Brooks K, Ramsahai J, Wang L, Pham NA, Shaw PA, Tsao MS, Garg S, Stockley T, Oza AM.

Clin Cancer Res. 2018 Dec 15;24(24):6168-6174. doi: 10.1158/1078-0432.CCR-18-1244. Epub 2018 Aug 14.

PMID:
30108107
28.

Clinical genetic testing outcome with multi-gene panel in Asian patients with multiple primary cancers.

Chan GHJ, Ong PY, Low JJH, Kong HL, Ow SGW, Tan DSP, Lim YW, Lim SE, Lee SC.

Oncotarget. 2018 Jul 17;9(55):30649-30660. doi: 10.18632/oncotarget.25769. eCollection 2018 Jul 17.

29.

Characterization and phase I study of CLR457, an orally bioavailable pan-class I PI3-kinase inhibitor.

Harding JJ, Bauer TM, Tan DSW, Bedard PL, Rodon J, Doi T, Schnell C, Iyer V, Baffert F, Radhakrishnan R, Fabre C, Juric D.

Invest New Drugs. 2019 Apr;37(2):271-281. doi: 10.1007/s10637-018-0627-4. Epub 2018 Aug 3.

30.

DeepDemosaicking: Adaptive Image Demosaicking via Multiple Deep Fully Convolutional Networks.

Tan DS, Chen WY, Hua KL.

IEEE Trans Image Process. 2018 Feb 7. doi: 10.1109/TIP.2018.2803341. [Epub ahead of print]

PMID:
29994510
31.

Letter by Aw et al Regarding Article, "Clinical Outcomes and Sustainability of Using CYP2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention".

Aw JWX, Tan DS, Goh LL.

Circ Genom Precis Med. 2018 Jul;11(7):e002253. doi: 10.1161/CIRCGEN.118.002253. No abstract available.

PMID:
29987115
32.

Synthesis of Benzannulated Medium-ring Lactams via a Tandem Oxidative Dearomatization-Ring Expansion Reaction.

Guney T, Wenderski TA, Boudreau MW, Tan DS.

Chemistry. 2018 Sep 6;24(50):13150-13157. doi: 10.1002/chem.201802880. Epub 2018 Aug 2.

PMID:
29936701
33.

Tumor molecular profiling of responders and non-responders following pembrolizumab monotherapy in chemotherapy resistant advanced cervical cancer.

Ngoi NYL, Heong V, Lee XW, Huang YQ, Thian YL, Choo BA, Lim D, Lim YW, Lim SE, Ilancheran A, Soong R, Tan DSP.

Gynecol Oncol Rep. 2018 Jan 31;24:1-5. doi: 10.1016/j.gore.2018.01.009. eCollection 2018 May.

34.

Liquid Biopsy for Advanced Non-Small Cell Lung Cancer (NSCLC): A Statement Paper from the IASLC.

Rolfo C, Mack PC, Scagliotti GV, Baas P, Barlesi F, Bivona TG, Herbst RS, Mok TS, Peled N, Pirker R, Raez LE, Reck M, Riess JW, Sequist LV, Shepherd FA, Sholl LM, Tan DSW, Wakelee HA, Wistuba II, Wynes MW, Carbone DP, Hirsch FR, Gandara DR.

J Thorac Oncol. 2018 Sep;13(9):1248-1268. doi: 10.1016/j.jtho.2018.05.030. Epub 2018 Jun 6. Review.

PMID:
29885479
35.

Biomarkers for Homologous Recombination Deficiency in Cancer.

Hoppe MM, Sundar R, Tan DSP, Jeyasekharan AD.

J Natl Cancer Inst. 2018 Jul 1;110(7):704-713. doi: 10.1093/jnci/djy085.

PMID:
29788099
36.

Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates.

Simoni Y, Becht E, Fehlings M, Loh CY, Koo SL, Teng KWW, Yeong JPS, Nahar R, Zhang T, Kared H, Duan K, Ang N, Poidinger M, Lee YY, Larbi A, Khng AJ, Tan E, Fu C, Mathew R, Teo M, Lim WT, Toh CK, Ong BH, Koh T, Hillmer AM, Takano A, Lim TKH, Tan EH, Zhai W, Tan DSW, Tan IB, Newell EW.

Nature. 2018 May;557(7706):575-579. doi: 10.1038/s41586-018-0130-2. Epub 2018 May 16.

PMID:
29769722
37.

Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency.

Simoni Y, Fehlings M, Kløverpris HN, McGovern N, Koo SL, Loh CY, Lim S, Kurioka A, Fergusson JR, Tang CL, Kam MH, Dennis K, Lim TKH, Fui ACY, Hoong CW, Chan JKY, Curotto de Lafaille M, Narayanan S, Baig S, Shabeer M, Toh SES, Tan HKK, Anicete R, Tan EH, Takano A, Klenerman P, Leslie A, Tan DSW, Tan IB, Ginhoux F, Newell EW.

Immunity. 2018 May 15;48(5):1060. doi: 10.1016/j.immuni.2018.04.028. No abstract available.

PMID:
29768165
38.

A Decade of Never-smokers Among Lung Cancer Patients-Increasing Trend and Improved Survival.

Toh CK, Ong WS, Lim WT, Tan DS, Ng QS, Kanesvaran R, Seow WJ, Ang MK, Tan EH.

Clin Lung Cancer. 2018 Sep;19(5):e539-e550. doi: 10.1016/j.cllc.2018.03.013. Epub 2018 Mar 17.

PMID:
29627315
39.

Targeting the metastatic niche through anti-angiogenic approaches in epidermal growth factor receptor mutant non-small cell lung cancer.

Tan WL, Tan DSW.

Transl Lung Cancer Res. 2018 Feb;7(Suppl 1):S13-S18. doi: 10.21037/tlcr.2017.11.12. No abstract available.

40.

Mutational Aberrations Detected in Mucinous Epithelial Ovarian Cancer of Asian Women.

Chay WY, Kwok LL, Tiong WN, Krisna SS, Lim KH, Iyer NG, Goh LK, Tan DS.

Int J Gynecol Cancer. 2018 Mar;28(3):428-436. doi: 10.1097/IGC.0000000000001138.

PMID:
29465505
41.

Elucidating the genomic architecture of Asian EGFR-mutant lung adenocarcinoma through multi-region exome sequencing.

Nahar R, Zhai W, Zhang T, Takano A, Khng AJ, Lee YY, Liu X, Lim CH, Koh TPT, Aung ZW, Lim TKH, Veeravalli L, Yuan J, Teo ASM, Chan CX, Poh HM, Chua IML, Liew AA, Lau DPX, Kwang XL, Toh CK, Lim WT, Lim B, Tam WL, Tan EH, Hillmer AM, Tan DSW.

Nat Commun. 2018 Jan 15;9(1):216. doi: 10.1038/s41467-017-02584-z.

42.

GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers.

Rasheed SAK, Leong HS, Lakshmanan M, Raju A, Dadlani D, Chong FT, Shannon NB, Rajarethinam R, Skanthakumar T, Tan EY, Hwang JSG, Lim KH, Tan DS, Ceppi P, Wang M, Tergaonkar V, Casey PJ, Iyer NG.

Oncogene. 2018 Mar;37(10):1340-1353. doi: 10.1038/s41388-017-0038-6. Epub 2017 Dec 19.

43.

Incidence of thromboembolic and bleeding events in patients with newly diagnosed nonvalvular atrial fibrillation: An Asian multicenter retrospective cohort study in Singapore.

Wee XT, Ho LM, Ho HK, Lee JY, Yap CW, William H, Chan LCE, Tay HC, Goh CEM, Tan DS.

Clin Cardiol. 2017 Dec;40(12):1218-1226. doi: 10.1002/clc.22811. Epub 2017 Dec 18.

44.

Drug Class, Renal Elimination, and Outcomes of Direct Oral Anticoagulants in Asian Patients: A Meta-Analysis.

Wang KL, Chiu CC, Giugliano RP, Tan DS, Lin CY, Lai EY, Goto S, Chiang CE.

J Stroke Cerebrovasc Dis. 2018 Apr;27(4):857-864. doi: 10.1016/j.jstrokecerebrovasdis.2017.10.027. Epub 2017 Nov 26. Review.

PMID:
29239808
45.

Targeting RET-driven cancers: lessons from evolving preclinical and clinical landscapes.

Drilon A, Hu ZI, Lai GGY, Tan DSW.

Nat Rev Clin Oncol. 2018 Mar;15(3):150. doi: 10.1038/nrclinonc.2017.188. Epub 2017 Nov 28.

PMID:
29182164
46.

Targeting RET-driven cancers: lessons from evolving preclinical and clinical landscapes.

Drilon A, Hu ZI, Lai GGY, Tan DSW.

Nat Rev Clin Oncol. 2018 Mar;15(3):151-167. doi: 10.1038/nrclinonc.2017.175. Epub 2017 Nov 14. Review. Erratum in: Nat Rev Clin Oncol. 2017 Nov 28;:.

PMID:
29134959
47.

A three gene immunohistochemical panel serves as an adjunct to clinical staging of patients with head and neck cancer.

Ong CJ, Shannon NB, Mueller S, Lek SM, Qiu X, Chong FT, Li K, Koh KKN, Tay GCA, Skanthakumar T, Hwang JSG, Hon Lim TK, Ang MK, Tan DSW, Tan NC, Tan HK, Soo KC, Iyer NG.

Oncotarget. 2017 Jun 19;8(45):79556-79566. doi: 10.18632/oncotarget.18568. eCollection 2017 Oct 3.

48.

Stereocontrolled Synthesis of Spiroketals: An Engine for Chemical and Biological Discovery.

Verano AL, Tan DS.

Isr J Chem. 2017 Apr;57(3-4):279-291. doi: 10.1002/ijch.201600134. Epub 2017 Mar 10.

49.

Expanded molecular interrogation for potential actionable targets in non-squamous non-small cell lung cancer.

Lau KW, Seng C, Lim TKH, Tan DSW.

Ann Transl Med. 2017 Sep;5(18):372. doi: 10.21037/atm.2017.08.42. Review.

50.

Improved Survival of Advanced Lung Cancer in Singapore Over the Past Decade.

Toh CK, Ong WS, Tan DS, Ng QS, Kanesvaran R, Fong KW, Ang MK, Tan EH, Lim WT.

Ann Acad Med Singapore. 2017 Sep;46(9):333-338.

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