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Acupuncture or acupressure for pain management during labour.

Smith CA, Collins CT, Levett KM, Armour M, Dahlen HG, Tan AL, Mesgarpour B.

Cochrane Database Syst Rev. 2020 Feb 7;2:CD009232. doi: 10.1002/14651858.CD009232.pub2. Review.


Genome-wide meta-analysis associates GPSM1 with type 2 diabetes, a plausible gene involved in skeletal muscle function.

Ding Q, Tan ALM, Parra EJ, Cruz M, Sim X, Teo YY, Long J, Alsafar H, Petretto E, Tai ES, Chen H.

J Hum Genet. 2020 Apr;65(4):411-420. doi: 10.1038/s10038-019-0720-3. Epub 2020 Jan 21.


Subcutaneous phaeohyphomycosis caused by Pleurostomophora richardsiae in a renal transplant recipient.

Tee LY, Tan BH, Tan AL, Busmanis I, Oh CC.

JAAD Case Rep. 2019 Dec 27;6(1):66-68. doi: 10.1016/j.jdcr.2019.10.027. eCollection 2020 Jan. No abstract available.


Timeliness of Infectious Diseases Referral and Inappropriate Antibiotic Usage Post-Referral in an Asian Tertiary Hospital.

Wee LE, Tan AL, Wijaya L, Chlebicki MP, Thumboo J, Tan BH.

Trop Med Infect Dis. 2019 Nov 18;4(4). pii: E137. doi: 10.3390/tropicalmed4040137.


Candida auris in Singapore: Genomic epidemiology, antifungal drug resistance, and identification using the updated 8.01 VITEK2 system.

Tan YE, Teo JQ, Rahman NBA, Ng OT, Kalisvar M, Tan AL, Koh TH, Ong RTH.

Int J Antimicrob Agents. 2019 Dec;54(6):709-715. doi: 10.1016/j.ijantimicag.2019.09.016. Epub 2019 Oct 7.


Integrated paired-end enhancer profiling and whole-genome sequencing reveals recurrent CCNE1 and IGF2 enhancer hijacking in primary gastric adenocarcinoma.

Ooi WF, Nargund AM, Lim KJ, Zhang S, Xing M, Mandoli A, Lim JQ, Ho SWT, Guo Y, Yao X, Lin SJ, Nandi T, Xu C, Ong X, Lee M, Tan AL, Lam YN, Teo JX, Kaneda A, White KP, Lim WK, Rozen SG, Teh BT, Li S, Skanderup AJ, Tan P.

Gut. 2019 Sep 21. pii: gutjnl-2018-317612. doi: 10.1136/gutjnl-2018-317612. [Epub ahead of print]


Development and validation of a real-time multiplex PCR assay for the detection of dermatophytes and Fusarium spp.

Koo SH, Teoh YL, Koh WL, Ochi H, Tan SK, Sim DMF, Jiang B, Tan AL, Tan TY, Lim SPR.

J Med Microbiol. 2019 Nov;68(11):1641-1648. doi: 10.1099/jmm.0.001082.


Travel Surveillance and Genomics Uncover a Hidden Zika Outbreak during the Waning Epidemic.

Grubaugh ND, Saraf S, Gangavarapu K, Watts A, Tan AL, Oidtman RJ, Ladner JT, Oliveira G, Matteson NL, Kraemer MUG, Vogels CBF, Hentoff A, Bhatia D, Stanek D, Scott B, Landis V, Stryker I, Cone MR, Kopp EW 4th, Cannons AC, Heberlein-Larson L, White S, Gillis LD, Ricciardi MJ, Kwal J, Lichtenberger PK, Magnani DM, Watkins DI, Palacios G, Hamer DH; GeoSentinel Surveillance Network, Gardner LM, Perkins TA, Baele G, Khan K, Morrison A, Isern S, Michael SF, Andersen KG.

Cell. 2019 Aug 22;178(5):1057-1071.e11. doi: 10.1016/j.cell.2019.07.018.


Factors driving frequent attendance at emergency departments for patients with head and neck cancer.

Tan AL, Iyer NG, Putri N, Nadkarni N, Skanthakumar T, Wong TH, Tay GCA.

Head Neck. 2019 Nov;41(11):3798-3805. doi: 10.1002/hed.25916. Epub 2019 Aug 18.


Reduction in stiffness of proximal leg muscles during the first 6 months of glucocorticoid therapy for giant cell arteritis: A pilot study using shear wave elastography.

Alfuraih AM, Tan AL, O'Connor P, Emery P, Mackie S, Wakefield RJ.

Int J Rheum Dis. 2019 Oct;22(10):1891-1899. doi: 10.1111/1756-185X.13667. Epub 2019 Jul 30.


Muscle stiffness in rheumatoid arthritis is not altered or associated with muscle weakness: A shear wave elastography study.

Alfuraih AM, Tan AL, O'Connor P, Emery P, Wakefield RJ.

Mod Rheumatol. 2019 Aug 1:1-9. doi: 10.1080/14397595.2019.1645374. [Epub ahead of print]


Normal values and test-retest variability of stimulated-echo diffusion tensor imaging and fat fraction measurements in the muscle.

Farrow M, Grainger AJ, Tan AL, Buch MH, Emery P, Ridgway JP, Feiweier T, Tanner SF, Biglands J.

Br J Radiol. 2019 Sep;92(1101):20190143. doi: 10.1259/bjr.20190143. Epub 2019 Jul 12.


The price of personal mobility: burden of injury and mortality from personal mobility devices in Singapore - a nationwide cohort study.

Tan AL; Trauma Coordinators and Trauma Service Representatives, Nadkarni N, Wong TH.

BMC Public Health. 2019 Jul 4;19(1):880. doi: 10.1186/s12889-019-7210-6.


HNF4α pathway mapping identifies wild-type IDH1 as a targetable metabolic node in gastric cancer.

Xu C, Ooi WF, Qamra A, Tan J, Chua BY, Ho SWT, Das K, Adam Isa ZF, Li Z, Yao X, Yan T, Xing M, Huang KK, Lin JS, Nandi T, Tay ST, Lee MH, Tan ALK, Ong X, Ashktorab H, Smoot D, Li S, Ng SC, Teh BT, Tan P.

Gut. 2020 Feb;69(2):231-242. doi: 10.1136/gutjnl-2018-318025. Epub 2019 May 8.


Risk factors and reasons for cancellation within 24 h of scheduled elective surgery in an academic medical centre: A cohort study.

Tan AL, Chiew CJ, Wang S, Abdullah HR, Lam SS, Ong ME, Tan HK, Wong TH.

Int J Surg. 2019 Jun;66:72-78. doi: 10.1016/j.ijsu.2019.04.009. Epub 2019 Apr 26.


MRI inflammation of the hand interosseous tendons occurs in anti-CCP-positive at-risk individuals and may precede the development of clinical synovitis.

Mankia K, D'Agostino MA, Rowbotham E, Hensor EM, Hunt L, Möller I, Miguel M, Mérida-Velasco JR, Murillo-González J, Naredo E, Nam JL, Tan AL, Freeston JE, Grainger A, Emery P.

Ann Rheum Dis. 2019 Jun;78(6):781-786. doi: 10.1136/annrheumdis-2018-214331. Epub 2019 Mar 23.


Referral patterns for genetic counselling of women diagnosed with tubo-ovarian or peritoneal high-grade serous carcinoma (HGSC) within the Auckland Gynaecological Oncology Centre.

Burling MJ, Gamet K, Eva L, Tan AL.

Aust N Z J Obstet Gynaecol. 2019 Jun;59(3):444-449. doi: 10.1111/ajo.12964. Epub 2019 Mar 18.


First Case of Ceftriaxone-Resistant Multidrug-Resistant Neisseria gonorrhoeae in Singapore.

Ko KKK, Chio MTW, Goh SS, Tan AL, Koh TH, Abdul Rahman NB.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e02624-18. doi: 10.1128/AAC.02624-18. Print 2019 May. No abstract available.


Muscle shear wave elastography in idiopathic inflammatory myopathies: a case-control study with MRI correlation.

Alfuraih AM, O'Connor P, Tan AL, Hensor EMA, Ladas A, Emery P, Wakefield RJ.

Skeletal Radiol. 2019 Aug;48(8):1209-1219. doi: 10.1007/s00256-019-03175-3. Epub 2019 Feb 27.


Patterns of referral and uptake of BReast CAncer (BRCA) gene testing of eligible women with ovarian cancer in New Zealand.

Fraser K, Tan AL, Innes C, Stephens R, Tristram A, Petrich S, Lintott C, Sykes PH, Gamet K, Christian A, Simcock B.

N Z Med J. 2019 Feb 22;132(1490):26-35.


The effect of ageing on shear wave elastography muscle stiffness in adults.

Alfuraih AM, Tan AL, O'Connor P, Emery P, Wakefield RJ.

Aging Clin Exp Res. 2019 Dec;31(12):1755-1763. doi: 10.1007/s40520-019-01139-0. Epub 2019 Feb 14.


Capturing sequence diversity in metagenomes with comprehensive and scalable probe design.

Metsky HC, Siddle KJ, Gladden-Young A, Qu J, Yang DK, Brehio P, Goldfarb A, Piantadosi A, Wohl S, Carter A, Lin AE, Barnes KG, Tully DC, Corleis B, Hennigan S, Barbosa-Lima G, Vieira YR, Paul LM, Tan AL, Garcia KF, Parham LA, Odia I, Eromon P, Folarin OA, Goba A; Viral Hemorrhagic Fever Consortium, Simon-Lorière E, Hensley L, Balmaseda A, Harris E, Kwon DS, Allen TM, Runstadler JA, Smole S, Bozza FA, Souza TML, Isern S, Michael SF, Lorenzana I, Gehrke L, Bosch I, Ebel G, Grant DS, Happi CT, Park DJ, Gnirke A, Sabeti PC, Matranga CB.

Nat Biotechnol. 2019 Feb;37(2):160-168. doi: 10.1038/s41587-018-0006-x. Epub 2019 Feb 4.


Interventions for treating urinary incontinence after stroke in adults.

Thomas LH, Coupe J, Cross LD, Tan AL, Watkins CL.

Cochrane Database Syst Rev. 2019 Feb 1;2:CD004462. doi: 10.1002/14651858.CD004462.pub4.


Molecular mechanisms of azole resistance in Candida bloodstream isolates.

Teo JQ, Lee SJ, Tan AL, Lim RS, Cai Y, Lim TP, Kwa AL.

BMC Infect Dis. 2019 Jan 17;19(1):63. doi: 10.1186/s12879-019-3672-5.


FURIN Inhibition Reduces Vascular Remodeling and Atherosclerotic Lesion Progression in Mice.

Yakala GK, Cabrera-Fuentes HA, Crespo-Avilan GE, Rattanasopa C, Burlacu A, George BL, Anand K, Mayan DC, Corlianò M, Hernández-Reséndiz S, Wu Z, Schwerk AMK, Tan ALJ, Trigueros-Motos L, Chèvre R, Chua T, Kleemann R, Liehn EA, Hausenloy DJ, Ghosh S, Singaraja RR.

Arterioscler Thromb Vasc Biol. 2019 Mar;39(3):387-401. doi: 10.1161/ATVBAHA.118.311903.


Epigenomic promoter alterations predict for benefit from immune checkpoint inhibition in metastatic gastric cancer.

Sundar R, Huang KK, Qamra A, Kim KM, Kim ST, Kang WK, Tan ALK, Lee J, Tan P.

Ann Oncol. 2019 Mar 1;30(3):424-430. doi: 10.1093/annonc/mdy550.


An amplicon-based sequencing framework for accurately measuring intrahost virus diversity using PrimalSeq and iVar.

Grubaugh ND, Gangavarapu K, Quick J, Matteson NL, De Jesus JG, Main BJ, Tan AL, Paul LM, Brackney DE, Grewal S, Gurfield N, Van Rompay KKA, Isern S, Michael SF, Coffey LL, Loman NJ, Andersen KG.

Genome Biol. 2019 Jan 8;20(1):8. doi: 10.1186/s13059-018-1618-7.


Pathophysiology, assessment and treatment of psoriatic dactylitis.

McGonagle D, Tan AL, Watad A, Helliwell P.

Nat Rev Rheumatol. 2019 Feb;15(2):113-122. doi: 10.1038/s41584-018-0147-9. Review.


Predictors of Change in Functional Outcome at six months and twelve months after Severe Injury: A Retrospective Cohort Study.

Tan AL, Chiong Y, Nadkarni N, Cheng JYX, Chiu MT, Wong TH.

World J Emerg Surg. 2018 Dec 3;13:57. doi: 10.1186/s13017-018-0217-y. eCollection 2018.


Impact of an alternating first-line antibiotics strategy in febrile neutropenia.

Tan BH, Guzman MRT, Donato LKS, Kalimuddin S, Lee WHL, Tan AL, Wong GC.

PLoS One. 2018 Nov 28;13(11):e0208039. doi: 10.1371/journal.pone.0208039. eCollection 2018.


Correction to: Candidemia in a major regional tertiary referral hospital - epidemiology, practice patterns and outcomes.

Teo JQ, Candra SR, Lee SJ, Chia SY, Leck H, Tan AL, Neo HP, Leow KW, Cai Y, Ee PLR, Lim TP, Lee W, Kwa AL.

Antimicrob Resist Infect Control. 2018 Nov 7;7:130. doi: 10.1186/s13756-018-0413-2. eCollection 2018.


Factors affecting clinical outcomes in the management of melioidosis in Singapore: a 16-year case series.

Chien JM, Saffari SE, Tan AL, Tan TT.

BMC Infect Dis. 2018 Sep 26;18(1):482. doi: 10.1186/s12879-018-3393-1.


The epidemiology of non-Candida yeast isolated from blood: The Asia Surveillance Study.

Lin SY, Lu PL, Tan BH, Chakrabarti A, Wu UI, Yang JH, Patel AK, Li RY, Watcharananan SP, Liu Z, Chindamporn A, Tan AL, Sun PL, Hsu LY, Chen YC; Asia Fungal Working Group (AFWG).

Mycoses. 2019 Feb;62(2):112-120. doi: 10.1111/myc.12852. Epub 2018 Oct 17.


Emergence of severe spondyloarthropathy-related entheseal pathology following successful vedolizumab therapy for inflammatory bowel disease.

Dubash S, Marianayagam T, Tinazzi I, Al-Araimi T, Pagnoux C, Weizman AV, Richette P, Tran Minh ML, Allez M, Singh A, Ciccia F, Hamlin J, Tan AL, Marzo-Ortega H, McGonagle D.

Rheumatology (Oxford). 2019 Jun 1;58(6):963-968. doi: 10.1093/rheumatology/key267.


Ethnicity-Specific Skeletal Muscle Transcriptional Signatures and Their Relevance to Insulin Resistance in Singapore.

Tan ALM, Langley SR, Tan CF, Chai JF, Khoo CM, Leow MK, Khoo EYH, Moreno-Moral A, Pravenec M, Rotival M, Sadananthan SA, Velan SS, Venkataraman K, Chong YS, Lee YS, Sim X, Stunkel W, Liu MH, Tai ES, Petretto E.

J Clin Endocrinol Metab. 2019 Feb 1;104(2):465-486. doi: 10.1210/jc.2018-00309.


Arrival of Candida auris Fungus in Singapore: Report of the First 3 Cases.

Tan YE, Tan AL.

Ann Acad Med Singapore. 2018 Jul;47(7):260-262. No abstract available.


The Asia Cornea Society Infectious Keratitis Study: A Prospective Multicenter Study of Infectious Keratitis in Asia.

Khor WB, Prajna VN, Garg P, Mehta JS, Xie L, Liu Z, Padilla MDB, Joo CK, Inoue Y, Goseyarakwong P, Hu FR, Nishida K, Kinoshita S, Puangsricharern V, Tan AL, Beuerman R, Young A, Sharma N, Haaland B, Mah FS, Tu EY, Stapleton FJ, Abbott RL, Tan DT; ACSIKS Group.

Am J Ophthalmol. 2018 Nov;195:161-170. doi: 10.1016/j.ajo.2018.07.040. Epub 2018 Aug 9.


Transcriptional analysis of immune genes in Epstein-Barr virus-associated gastric cancer and association with clinical outcomes.

Sundar R, Qamra A, Tan ALK, Zhang S, Ng CCY, Teh BT, Lee J, Kim KM, Tan P.

Gastric Cancer. 2018 Nov;21(6):1064-1070. doi: 10.1007/s10120-018-0851-9. Epub 2018 Jun 18.


Wolbachia wStri Blocks Zika Virus Growth at Two Independent Stages of Viral Replication.

Schultz MJ, Tan AL, Gray CN, Isern S, Michael SF, Frydman HM, Connor JH.

mBio. 2018 May 22;9(3). pii: e00738-18. doi: 10.1128/mBio.00738-18.


Field-deployable viral diagnostics using CRISPR-Cas13.

Myhrvold C, Freije CA, Gootenberg JS, Abudayyeh OO, Metsky HC, Durbin AF, Kellner MJ, Tan AL, Paul LM, Parham LA, Garcia KF, Barnes KG, Chak B, Mondini A, Nogueira ML, Isern S, Michael SF, Lorenzana I, Yozwiak NL, MacInnis BL, Bosch I, Gehrke L, Zhang F, Sabeti PC.

Science. 2018 Apr 27;360(6387):444-448. doi: 10.1126/science.aas8836.


Donor-Derived Candida dubliniensis Resulting in Perigraft Abscesses in a Liver Transplant Recipient Proven by Whole Genome Sequencing: A Case Report.

Teh YE, Ang MLT, La MV, Gunalan V, Tan CK, Tan AL, Lin RTP, Tan TT, Jeyaraj PR, Cumaraswamy S, Tan BH.

Transplant Proc. 2018 Apr;50(3):915-919. doi: 10.1016/j.transproceed.2018.01.017.


[1-(Pyrazin-2-yl)ethylidene]hydrazine: a new multitopic ligand for the design of hybrid molecular frameworks.

Kassim MA, Yassin UHM, Tan AL, Usman A, Hamid MHSA.

Acta Crystallogr C Struct Chem. 2018 Apr 1;74(Pt 4):424-427. doi: 10.1107/S2053229618003273. Epub 2018 Mar 7.


A mechanistic pan-cancer pathway model informed by multi-omics data interprets stochastic cell fate responses to drugs and mitogens.

Bouhaddou M, Barrette AM, Stern AD, Koch RJ, DiStefano MS, Riesel EA, Santos LC, Tan AL, Mertz AE, Birtwistle MR.

PLoS Comput Biol. 2018 Mar 26;14(3):e1005985. doi: 10.1371/journal.pcbi.1005985. eCollection 2018 Mar. Erratum in: PLoS Comput Biol. 2018 Jul 9;14(7):e1006189.


Case Report: Spontaneous Hemorrhage of a Rare Renal Tumor in the Native Kidney of a Renal Transplant Recipient.

Tan AL, Lawson M, Preston J, Wood S, Griffin A, Rhee H.

Transplant Proc. 2018 Apr;50(3):902-904. doi: 10.1016/j.transproceed.2017.11.031. Epub 2018 Mar 16.


Tinea unguium onychomycosis caused by dermatophytes: a ten-year (2005-2014) retrospective study in a tertiary hospital in Singapore.

Pang SM, Pang JYY, Fook-Chong S, Tan AL.

Singapore Med J. 2018 Oct;59(10):524-527. doi: 10.11622/smedj.2018037. Epub 2018 Mar 19.


MRI of psoriatic nail disease pre- and post-TNF inhibitor therapy shows persistent subclinical inflammation after 6 months despite good clinical response.

Ash Z, Tan AL, Hodgson RJ, Grainger A, Marzo-Ortega H, McGonagle DG.

RMD Open. 2018 Feb 2;4(1):e000599. doi: 10.1136/rmdopen-2017-000599. eCollection 2018. No abstract available.


Comorbidities in Anti-Cyclic Citrullinated Peptide Positive At-Risk Individuals Do Not Differ from Those Patients with Early Inflammatory Arthritis.

Twigg S, Nikiphorou E, Nam JL, Hunt L, Mankia K, Pentony PE, Freeston JE, Tan AL, Emery P.

Front Med (Lausanne). 2018 Feb 19;5:35. doi: 10.3389/fmed.2018.00035. eCollection 2018.


Quantification of desoxyrhapontigenin (4-methoxyresveratrol) in rat plasma by LC-MS/MS: Application to pre-clinical pharmacokinetic study.

Dai Y, Tan ALC, Chen H, Ong PS, Xiang X, Wu J, Lin HS.

J Pharm Biomed Anal. 2018 May 10;153:95-101. doi: 10.1016/j.jpba.2018.02.026. Epub 2018 Feb 13.


Genomic and Epigenomic Profiling of High-Risk Intestinal Metaplasia Reveals Molecular Determinants of Progression to Gastric Cancer.

Huang KK, Ramnarayanan K, Zhu F, Srivastava S, Xu C, Tan ALK, Lee M, Tay S, Das K, Xing M, Fatehullah A, Alkaff SMF, Lim TKH, Lee J, Ho KY, Rozen SG, Teh BT, Barker N, Chia CK, Khor C, Ooi CJ, Fock KM, So J, Lim WC, Ling KL, Ang TL, Wong A, Rao J, Rajnakova A, Lim LG, Yap WM, Teh M, Yeoh KG, Tan P.

Cancer Cell. 2018 Jan 8;33(1):137-150.e5. doi: 10.1016/j.ccell.2017.11.018. Epub 2017 Dec 28.


An investigation into the variability between different shear wave elastography systems in muscle.

Alfuraih AM, O'Connor P, Tan AL, Hensor E, Emery P, Wakefield RJ.

Med Ultrason. 2017 Nov 29;19(4):392-400. doi: 10.11152/mu-1113.

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