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Items: 1 to 50 of 326

1.

Biochemical efficacy of tioguanine in autoimmune hepatitis: a retrospective review of practice in the Netherlands.

van den Brand FF, van Nieuwkerk CMJ, Verwer BJ, de Boer YS, de Boer NKH, Mulder CJJ, Bloemena E, Bakker CM, Vrolijk JM, Drenth JPH, Tan ACITL, Ter Borg F, Ter Borg MJ, van den Hazel SJ, Inderson A, Tushuizen ME, Bouma G.

Aliment Pharmacol Ther. 2018 Aug 15. doi: 10.1111/apt.14939. [Epub ahead of print]

PMID:
30109891
2.

Final Report of a Phase I Trial of Olaparib with Cetuximab and Radiation for Heavy Smoker Patients with Locally Advanced Head and Neck Cancer.

Karam SD, Reddy K, Blatchford P, Waxweiler T, DeLouize AM, Oweida A, Somerset H, Marshall C, Young C, Davies KD, Kane M, Tan AC, Wang XJ, Jimeno A, Aisner DL, Bowles DW, Raben D.

Clin Cancer Res. 2018 Jul 3. pii: clincanres.0467.2018. doi: 10.1158/1078-0432.CCR-18-0467. [Epub ahead of print]

PMID:
30084837
3.

CD44 facilitates epithelial to mesenchymal transition phenotypic change at acquisition of resistance to EGFR kinase inhibitors in lung cancer.

Suda K, Murakami I, Yu H, Kim J, Tan AC, Mizuuchi H, Rozeboom LM, Ellison K, Rivard CJ, Mitsudomi T, Hirsch FR.

Mol Cancer Ther. 2018 Jul 26. pii: molcanther.1279.2017. doi: 10.1158/1535-7163.MCT-17-1279. [Epub ahead of print]

PMID:
30049789
4.

Resistance to radiotherapy and PD-L1 blockade is mediated by TIM-3 upregulation and regulatory T-cell infiltration.

Oweida A, Hararah M, Phan AV, Binder DC, Bhatia S, Lennon S, Bukkapatnam S, Van Court B, Uyanga N, Darragh L, Kim HM, Raben D, Tan AC, Heasley L, Clambey ET, Nemenoff RA, Karam SD.

Clin Cancer Res. 2018 Jul 24. pii: clincanres.1038.2018. doi: 10.1158/1078-0432.CCR-18-1038. [Epub ahead of print]

PMID:
30042205
5.

A Metal Stent in a Colostomy Obstruction.

van Gils NA, Cornelissen JGHM, Tan ACITL.

GE Port J Gastroenterol. 2018 Jun;25(4):214-215. doi: 10.1159/000481625. Epub 2018 Jan 10. No abstract available.

6.

GSEA-InContext: identifying novel and common patterns in expression experiments.

Powers RK, Goodspeed A, Pielke-Lombardo H, Tan AC, Costello JC.

Bioinformatics. 2018 Jul 1;34(13):i555-i564. doi: 10.1093/bioinformatics/bty271.

7.

Innate Genetic Evolution of Lung Cancers and Spatial Heterogeneity: Analysis of Treatment-Naïve Lesions.

Suda K, Kim J, Murakami I, Rozeboom L, Shimoji M, Shimizu S, Rivard CJ, Mitsudomi T, Tan AC, Hirsch FR.

J Thorac Oncol. 2018 Jun 19. pii: S1556-0864(18)30692-0. doi: 10.1016/j.jtho.2018.05.039. [Epub ahead of print]

8.

AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells.

Pei S, Minhajuddin M, Adane B, Khan N, Stevens BM, Mack SC, Lai S, Rich JN, Inguva A, Shannon KM, Kim H, Tan AC, Myers JR, Ashton JM, Neff T, Pollyea DA, Smith CA, Jordan CT.

Cell Stem Cell. 2018 Jul 5;23(1):86-100.e6. doi: 10.1016/j.stem.2018.05.021. Epub 2018 Jun 14.

PMID:
29910151
9.

Systems Pharmacology-Based Approach of Connecting Disease Genes in Genome-Wide Association Studies with Traditional Chinese Medicine.

Kim J, Yoo M, Shin J, Kim H, Kang J, Tan AC.

Int J Genomics. 2018 Mar 22;2018:7697356. doi: 10.1155/2018/7697356. eCollection 2018.

10.

IMPACT web portal: oncology database integrating molecular profiles with actionable therapeutics.

Hintzsche JD, Yoo M, Kim J, Amato CM, Robinson WA, Tan AC.

BMC Med Genomics. 2018 Apr 20;11(Suppl 2):26. doi: 10.1186/s12920-018-0350-1.

11.

Unexpected amebic colitis presenting with rectal bleeding and perforation after biopsy.

de Leijer JH, Tan ACITL, Mulder B, Zomer SF.

Gastrointest Endosc. 2018 Sep;88(3):565-566. doi: 10.1016/j.gie.2018.04.2345. Epub 2018 Apr 22. No abstract available.

PMID:
29689256
12.

Exploring the molecular mechanisms of Traditional Chinese Medicine components using gene expression signatures and connectivity map.

Yoo M, Shin J, Kim H, Kim J, Kang J, Tan AC.

Comput Methods Programs Biomed. 2018 Apr 4. pii: S0169-2607(17)30851-9. doi: 10.1016/j.cmpb.2018.04.002. [Epub ahead of print]

13.

Genetic Analysis of 779 Advanced Differentiated and Anaplastic Thyroid Cancers.

Pozdeyev N, Gay LM, Sokol ES, Hartmaier R, Deaver KE, Davis S, French JD, Borre PV, LaBarbera DV, Tan AC, Schweppe RE, Fishbein L, Ross JS, Haugen BR, Bowles DW.

Clin Cancer Res. 2018 Jul 1;24(13):3059-3068. doi: 10.1158/1078-0432.CCR-18-0373. Epub 2018 Apr 3.

PMID:
29615459
14.

Fluid hydration to prevent post-ERCP pancreatitis in average- to high-risk patients receiving prophylactic rectal NSAIDs (FLUYT trial): study protocol for a randomized controlled trial.

Smeets XJNM, da Costa DW, Fockens P, Mulder CJJ, Timmer R, Kievit W, Zegers M, Bruno MJ, Besselink MGH, Vleggaar FP, van der Hulst RWM, Poen AC, Heine GDN, Venneman NG, Kolkman JJ, Baak LC, Römkens TEH, van Dijk SM, Hallensleben NDL, van de Vrie W, Seerden TCJ, Tan ACITL, Voorburg AMCJ, Poley JW, Witteman BJ, Bhalla A, Hadithi M, Thijs WJ, Schwartz MP, Vrolijk JM, Verdonk RC, van Delft F, Keulemans Y, van Goor H, Drenth JPH, van Geenen EJM; Dutch Pancreatitis Study Group.

Trials. 2018 Apr 2;19(1):207. doi: 10.1186/s13063-018-2583-x.

15.

Salivary Gland Cancer Patient-Derived Xenografts Enable Characterization of Cancer Stem Cells and New Gene Events Associated with Tumor Progression.

Keysar SB, Eagles JR, Miller B, Jackson BC, Chowdhury FN, Reisinger J, Chimed TS, Le PN, Morton JJ, Somerset HL, Varella-Garcia M, Tan AC, Song JI, Bowles DW, Reyland ME, Jimeno A.

Clin Cancer Res. 2018 Jun 15;24(12):2935-2943. doi: 10.1158/1078-0432.CCR-17-3871. Epub 2018 Mar 19.

PMID:
29555661
16.

Reply.

Tan ACS, Freund KB, Sarraf D.

Retina. 2018 May;38(5):e37-e38. doi: 10.1097/IAE.0000000000002148. No abstract available.

PMID:
29554079
17.

GENIPAC: A Genomic Information Portal for Head and Neck Cancer Cell Systems.

Lee BKB, Gan CP, Chang JK, Tan JL, Fadlullah MZ, Abdul Rahman ZA, Prime SS, Gutkind JS, Liew CS, Khang TF, Tan AC, Cheong SC.

J Dent Res. 2018 Jul;97(8):909-916. doi: 10.1177/0022034518759038. Epub 2018 Mar 7.

PMID:
29512401
18.

ALK is a critical regulator of the MYC-signaling axis in ALK positive lung cancer.

Pilling AB, Kim J, Estrada-Bernal A, Zhou Q, Le AT, Singleton KR, Heasley LE, Tan AC, DeGregori J, Doebele RC.

Oncotarget. 2018 Jan 16;9(10):8823-8835. doi: 10.18632/oncotarget.24260. eCollection 2018 Feb 6.

19.

Antitumor activity of the polo-like kinase inhibitor, TAK-960, against preclinical models of colorectal cancer.

Klauck PJ, Bagby SM, Capasso A, Bradshaw-Pierce EL, Selby HM, Spreafico A, Tentler JJ, Tan AC, Kim J, Arcaroli JJ, Purkey A, Messersmith WA, Kuida K, Eckhardt SG, Pitts TM.

BMC Cancer. 2018 Feb 5;18(1):136. doi: 10.1186/s12885-018-4036-z.

20.

Cisplatin-induced syndrome of inappropriate antidiuretic hormone secretion (SIADH) with life-threatening hyponatraemia.

Tan AC, Marx GM.

BMJ Case Rep. 2018 Jan 31;2018. pii: bcr-2017-222948. doi: 10.1136/bcr-2017-222948.

PMID:
29386213
21.

Deep learning of mutation-gene-drug relations from the literature.

Lee K, Kim B, Choi Y, Kim S, Shin W, Lee S, Park S, Kim S, Tan AC, Kang J.

BMC Bioinformatics. 2018 Jan 25;19(1):21. doi: 10.1186/s12859-018-2029-1.

22.

Optical coherence tomography angiography: a review of current and future clinical applications.

Ang M, Tan ACS, Cheung CMG, Keane PA, Dolz-Marco R, Sng CCA, Schmetterer L.

Graefes Arch Clin Exp Ophthalmol. 2018 Feb;256(2):237-245. doi: 10.1007/s00417-017-3896-2. Epub 2018 Jan 9. Review.

PMID:
29318383
23.

A Pilot Study of Biomedical Text Comprehension using an Attention-Based Deep Neural Reader: Design and Experimental Analysis.

Kim S, Park D, Choi Y, Lee K, Kim B, Jeon M, Kim J, Tan AC, Kang J.

JMIR Med Inform. 2018 Jan 5;6(1):e2. doi: 10.2196/medinform.8751.

24.

IMAGING OF PIGMENT EPITHELIAL DETACHMENTS WITH OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.

Tan ACS, Freund KB, Balaratnasingam C, Simhaee D, Yannuzzi LA.

Retina. 2017 Dec 29. doi: 10.1097/IAE.0000000000002016. [Epub ahead of print]

PMID:
29293207
25.

Randomized controlled trial evaluating a novel community eye care programme for elderly individuals with visual impairment.

Tan AC, Man R, Wong CW, Lee SY, Lamoureux EL, Ang M.

Clin Exp Ophthalmol. 2017 Dec 28. doi: 10.1111/ceo.13140. [Epub ahead of print]

PMID:
29282844
26.

Author Response: The Evolution of the Plateau, an Optical Coherence Tomography Signature Seen in Geographic Atrophy.

Tan ACS, Dansingani KK, Curcio CA, Freund KB.

Invest Ophthalmol Vis Sci. 2017 Dec 1;58(14):6196. doi: 10.1167/iovs.17-23339. No abstract available.

27.

Design and development of low cost polyurethane biopolymer based on castor oil and glycerol for biomedical applications.

Tan ACW, Polo-Cambronell BJ, Provaggi E, Ardila-Suárez C, Ramirez-Caballero GE, Baldovino-Medrano VG, Kalaskar DM.

Biopolymers. 2018 Feb;109(2). doi: 10.1002/bip.23078. Epub 2017 Nov 21.

28.

Cadaveric Anatomical Study of Sural Nerve: Where is The Safe Area for Endoscopic Gastrocnemius Recession?

Tan ACK, Tang ZH, Fadil MFBM.

Open Orthop J. 2017 Sep 30;11:1094-1098. doi: 10.2174/1874325001711011094. eCollection 2017. Review.

29.

PAGER 2.0: an update to the pathway, annotated-list and gene-signature electronic repository for Human Network Biology.

Yue Z, Zheng Q, Neylon MT, Yoo M, Shin J, Zhao Z, Tan AC, Chen JY.

Nucleic Acids Res. 2018 Jan 4;46(D1):D668-D676. doi: 10.1093/nar/gkx1040.

30.

Evaluation of the efficacy of dasatinib, a Src/Abl inhibitor, in colorectal cancer cell lines and explant mouse model.

Scott AJ, Song EK, Bagby S, Purkey A, McCarter M, Gajdos C, Quackenbush KS, Cross B, Pitts TM, Tan AC, Eckhardt SG, Fenton H, Arcaroli J, Messersmith WA.

PLoS One. 2017 Nov 1;12(11):e0187173. doi: 10.1371/journal.pone.0187173. eCollection 2017.

31.

ALK Inhibitor Response in Melanomas Expressing EML4-ALK Fusions and Alternate ALK Isoforms.

Couts KL, Bemis J, Turner JA, Bagby SM, Murphy D, Christiansen J, Hintzsche JD, Le A, Pitts TM, Wells K, Applegate A, Amato C, Multani P, Chow-Maneval E, Tentler JJ, Shellman YG, Rioth MJ, Tan AC, Gonzalez R, Medina T, Doebele RC, Robinson WA.

Mol Cancer Ther. 2018 Jan;17(1):222-231. doi: 10.1158/1535-7163.MCT-17-0472. Epub 2017 Oct 20.

PMID:
29054983
32.

Correlating Ki67 and other prognostic markers with Oncotype DX recurrence score in early estrogen receptor-positive breast cancer.

Tan AC, Li BT, Nahar K, Danieletto S, Fong ES, Currer T, Parasyn A, Middleton P, Wong H, Smart D, Rutovitz JJ, McCloud P, Hughes TM, Marx GM.

Asia Pac J Clin Oncol. 2018 Apr;14(2):e161-e166. doi: 10.1111/ajco.12779. Epub 2017 Sep 29.

PMID:
28960862
33.

An overview of the clinical applications of optical coherence tomography angiography.

Tan ACS, Tan GS, Denniston AK, Keane PA, Ang M, Milea D, Chakravarthy U, Cheung CMG.

Eye (Lond). 2018 Feb;32(2):262-286. doi: 10.1038/eye.2017.181. Epub 2017 Sep 8. Review.

PMID:
28885606
34.

Molecular Analyses Reveal Inflammatory Mediators in the Solid Component and Cyst Fluid of Human Adamantinomatous Craniopharyngioma.

Donson AM, Apps J, Griesinger AM, Amani V, Witt DA, Anderson RCE, Niazi TN, Grant G, Souweidane M, Johnston JM, Jackson EM, Kleinschmidt-DeMasters BK, Handler MH, Tan AC, Gore L, Virasami A, Gonzalez-Meljem JM, Jacques TS, Martinez-Barbera JP, Foreman NK, Hankinson TC; Advancing Treatment for Pediatric Craniopharyngioma Consortium.

J Neuropathol Exp Neurol. 2017 Sep 1;76(9):779-788. doi: 10.1093/jnen/nlx061.

PMID:
28859336
35.

Identification of imaging features that determine quality and repeatability of retinal capillary plexus density measurements in OCT angiography.

Fenner BJ, Tan GSW, Tan ACS, Yeo IYS, Wong TY, Cheung GCM.

Br J Ophthalmol. 2018 Apr;102(4):509-514. doi: 10.1136/bjophthalmol-2017-310700. Epub 2017 Aug 16.

PMID:
28814409
36.

Functions of nonsuicidal self-injury in Singapore adolescents: Implications for intervention.

Ong SH, Tan ACY, Liang WZ.

Asian J Psychiatr. 2017 Aug;28:47-50. doi: 10.1016/j.ajp.2017.03.015. Epub 2017 Mar 18.

PMID:
28784396
37.

Sorafenib targets the mitochondrial electron transport chain complexes and ATP synthase to activate the PINK1-Parkin pathway and modulate cellular drug response.

Zhang C, Liu Z, Bunker E, Ramirez A, Lee S, Peng Y, Tan AC, Eckhardt SG, Chapnick DA, Liu X.

J Biol Chem. 2017 Sep 8;292(36):15105-15120. doi: 10.1074/jbc.M117.783175. Epub 2017 Jul 3.

PMID:
28673964
38.

Efficacy and Molecular Mechanisms of Differentiated Response to the Aurora and Angiogenic Kinase Inhibitor ENMD-2076 in Preclinical Models of p53-Mutated Triple-Negative Breast Cancer.

Ionkina AA, Tentler JJ, Kim J, Capasso A, Pitts TM, Ryall KA, Howison RR, Kabos P, Sartorius CA, Tan AC, Eckhardt SG, Diamond JR.

Front Oncol. 2017 May 15;7:94. doi: 10.3389/fonc.2017.00094. eCollection 2017.

39.

Resistance to RET-Inhibition in RET-Rearranged NSCLC Is Mediated By Reactivation of RAS/MAPK Signaling.

Nelson-Taylor SK, Le AT, Yoo M, Schubert L, Mishall KM, Doak A, Varella-Garcia M, Tan AC, Doebele RC.

Mol Cancer Ther. 2017 Aug;16(8):1623-1633. doi: 10.1158/1535-7163.MCT-17-0008. Epub 2017 May 12.

40.

The Evolution of Outer Retinal Tubulation, a Neurodegeneration and Gliosis Prominent in Macular Diseases.

Dolz-Marco R, Litts KM, Tan ACS, Freund KB, Curcio CA.

Ophthalmology. 2017 Sep;124(9):1353-1367. doi: 10.1016/j.ophtha.2017.03.043. Epub 2017 Apr 26.

PMID:
28456420
41.

The Evolution of the Plateau, an Optical Coherence Tomography Signature Seen in Geographic Atrophy.

Tan ACS, Astroz P, Dansingani KK, Slakter JS, Yannuzzi LA, Curcio CA, Freund KB.

Invest Ophthalmol Vis Sci. 2017 Apr 1;58(4):2349-2358. doi: 10.1167/iovs.16-21237.

42.

Understanding CD8+ T-cell responses toward the native and alternate HLA-A*02:01-restricted WT1 epitope.

Nguyen TH, Tan AC, Xiang SD, Goubier A, Harland KL, Clemens EB, Plebanski M, Kedzierska K.

Clin Transl Immunology. 2017 Mar 17;6(3):e134. doi: 10.1038/cti.2017.4. eCollection 2017 Mar.

43.

Immune Checkpoint Inhibitors for Brain Metastases.

Tan AC, Heimberger AB, Menzies AM, Pavlakis N, Khasraw M.

Curr Oncol Rep. 2017 Jun;19(6):38. doi: 10.1007/s11912-017-0596-3. Review.

PMID:
28417311
44.

Co-dependency of PKCδ and K-Ras: inverse association with cytotoxic drug sensitivity in KRAS mutant lung cancer.

Ohm AM, Tan AC, Heasley LE, Reyland ME.

Oncogene. 2017 Jul 27;36(30):4370-4378. doi: 10.1038/onc.2017.27. Epub 2017 Apr 3.

45.

Immune Checkpoint Inhibitors in Gliomas.

Tan AC, Heimberger AB, Khasraw M.

Curr Oncol Rep. 2017 Apr;19(4):23. doi: 10.1007/s11912-017-0586-5. Review.

PMID:
28303490
46.

Whole-exome sequencing identifies recurrent SF3B1 R625 mutation and comutation of NF1 and KIT in mucosal melanoma.

Hintzsche JD, Gorden NT, Amato CM, Kim J, Wuensch KE, Robinson SE, Applegate AJ, Couts KL, Medina TM, Wells KR, Wisell JA, McCarter MD, Box NF, Shellman YG, Gonzalez RC, Lewis KD, Tentler JJ, Tan AC, Robinson WA.

Melanoma Res. 2017 Jun;27(3):189-199. doi: 10.1097/CMR.0000000000000345.

47.

DeSigN: connecting gene expression with therapeutics for drug repurposing and development.

Lee BK, Tiong KH, Chang JK, Liew CS, Abdul Rahman ZA, Tan AC, Khang TF, Cheong SC.

BMC Genomics. 2017 Jan 25;18(Suppl 1):934. doi: 10.1186/s12864-016-3260-7.

48.

Three Cases of Erdheim-Chester Disease With Intraocular Manifestations: Imaging and Histopathology Findings of a Rare Entity.

Tan ACS, Yzer S, Atebara N, Marr BP, Verdijk RM, Dalm VASH, Freund KB, Yannuzzi L, Missotten T.

Am J Ophthalmol. 2017 Apr;176:141-147. doi: 10.1016/j.ajo.2017.01.017. Epub 2017 Jan 30.

PMID:
28153505
49.

A Genome-Wide Loss-of-Function Screen Identifies SLC26A2 as a Novel Mediator of TRAIL Resistance.

Dimberg LY, Towers CG, Behbakht K, Hotz TJ, Kim J, Fosmire S, Porter CC, Tan AC, Thorburn A, Ford HL.

Mol Cancer Res. 2017 Apr;15(4):382-394. doi: 10.1158/1541-7786.MCR-16-0234. Epub 2017 Jan 20.

50.

Context-dependent role for chromatin remodeling component PBRM1/BAF180 in clear cell renal cell carcinoma.

Murakami A, Wang L, Kalhorn S, Schraml P, Rathmell WK, Tan AC, Nemenoff R, Stenmark K, Jiang BH, Reyland ME, Heasley L, Hu CJ.

Oncogenesis. 2017 Jan 16;6(1):e287. doi: 10.1038/oncsis.2016.89.

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