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Items: 1 to 50 of 253

1.

Synthetic protein-conductive membrane nanopores built with DNA.

Diederichs T, Pugh G, Dorey A, Xing Y, Burns JR, Hung Nguyen Q, Tornow M, Tampé R, Howorka S.

Nat Commun. 2019 Nov 4;10(1):5018. doi: 10.1038/s41467-019-12639-y.

2.

Ribosome recycling in mRNA translation, quality control, and homeostasis.

Nürenberg-Goloub E, Tampé R.

Biol Chem. 2019 Oct 1. pii: /j/bchm.just-accepted/hsz-2019-0279/hsz-2019-0279.xml. doi: 10.1515/hsz-2019-0279. [Epub ahead of print]

PMID:
31665102
3.

Peptide translocation by the lysosomal ABC transporter TAPL is regulated by coupling efficiency and activation energy.

Bock C, Zollmann T, Lindt KA, Tampé R, Abele R.

Sci Rep. 2019 Aug 15;9(1):11884. doi: 10.1038/s41598-019-48343-6.

4.

Conformation space of a heterodimeric ABC exporter under turnover conditions.

Hofmann S, Januliene D, Mehdipour AR, Thomas C, Stefan E, Brüchert S, Kuhn BT, Geertsma ER, Hummer G, Tampé R, Moeller A.

Nature. 2019 Jul;571(7766):580-583. doi: 10.1038/s41586-019-1391-0. Epub 2019 Jul 17.

PMID:
31316210
5.

ABCE1 Controls Ribosome Recycling by an Asymmetric Dynamic Conformational Equilibrium.

Gouridis G, Hetzert B, Kiosze-Becker K, de Boer M, Heinemann H, Nürenberg-Goloub E, Cordes T, Tampé R.

Cell Rep. 2019 Jul 16;28(3):723-734.e6. doi: 10.1016/j.celrep.2019.06.052.

6.

Synthetic and genetic dimers as quantification ruler for single-molecule counting with PALM.

Baldering TN, Dietz MS, Gatterdam K, Karathanasis C, Wieneke R, Tampé R, Heilemann M.

Mol Biol Cell. 2019 Jun 1;30(12):1369-1376. doi: 10.1091/mbc.E18-10-0661. Epub 2019 Apr 10.

7.

Multivalent Chelators for In Vivo Protein Labeling.

Wieneke R, Tampé R.

Angew Chem Int Ed Engl. 2019 Jun 17;58(25):8278-8290. doi: 10.1002/anie.201811293. Epub 2019 Mar 27. Review.

PMID:
30919542
8.

Optical control of the antigen translocation by synthetic photo-conditional viral inhibitors.

Braner M, Koller N, Knauer J, Herbring V, Hank S, Wieneke R, Tampé R.

Chem Sci. 2018 Dec 17;10(7):2001-2005. doi: 10.1039/c8sc04863k. eCollection 2019 Feb 21.

9.

Lysosomal targeting of the ABC transporter TAPL is determined by membrane-localized charged residues.

Graab P, Bock C, Weiss K, Hirth A, Koller N, Braner M, Jung J, Loehr F, Tampé R, Behrends C, Abele R.

J Biol Chem. 2019 May 3;294(18):7308-7323. doi: 10.1074/jbc.RA118.007071. Epub 2019 Mar 15.

PMID:
30877195
10.

Modulation of TAP-dependent antigen compartmentalization during human monocyte-to-DC differentiation.

Döring M, Blees H, Koller N, Tischer-Zimmermann S, Müsken M, Henrich F, Becker J, Grabski E, Wang J, Janssen H, Zuschratter W, Neefjes J, Klawonn F, Eiz-Vesper B, Tampé R, Kalinke U.

Blood Adv. 2019 Mar 26;3(6):839-850. doi: 10.1182/bloodadvances.2018027268.

11.

MHC I chaperone complexes shaping immunity.

Thomas C, Tampé R.

Curr Opin Immunol. 2019 Jun;58:9-15. doi: 10.1016/j.coi.2019.01.001. Epub 2019 Feb 14. Review.

PMID:
30771631
12.

Control of mRNA Translation by Versatile ATP-Driven Machines.

Gerovac M, Tampé R.

Trends Biochem Sci. 2019 Feb;44(2):167-180. doi: 10.1016/j.tibs.2018.11.003. Epub 2018 Dec 7. Review.

PMID:
30527974
13.

Live-cell labeling of endogenous proteins with nanometer precision by transduced nanobodies.

Klein A, Hank S, Raulf A, Joest EF, Tissen F, Heilemann M, Wieneke R, Tampé R.

Chem Sci. 2018 Aug 20;9(40):7835-7842. doi: 10.1039/c8sc02910e. eCollection 2018 Oct 28.

14.

Structural and functional insights into the interaction and targeting hub TMD0 of the polypeptide transporter TAPL.

Bock C, Löhr F, Tumulka F, Reichel K, Würz J, Hummer G, Schäfer L, Tampé R, Joseph B, Bernhard F, Dötsch V, Abele R.

Sci Rep. 2018 Oct 23;8(1):15662. doi: 10.1038/s41598-018-33841-w.

15.

Ribosome recycling is coordinated by processive events in two asymmetric ATP sites of ABCE1.

Nürenberg-Goloub E, Heinemann H, Gerovac M, Tampé R.

Life Sci Alliance. 2018 Jun 14;1(3). pii: e201800095. doi: 10.26508/lsa.201800095.

16.

ABC Transporters in Dynamic Macromolecular Assemblies.

Trowitzsch S, Tampé R.

J Mol Biol. 2018 Oct 26;430(22):4481-4495. doi: 10.1016/j.jmb.2018.07.028. Epub 2018 Aug 5. Review.

PMID:
30089236
17.

Tris -N-Nitrilotriacetic Acid Fluorophore as a Self-Healing Dye for Single-Molecule Fluorescence Imaging.

Glembockyte V, Wieneke R, Gatterdam K, Gidi Y, Tampé R, Cosa G.

J Am Chem Soc. 2018 Sep 5;140(35):11006-11012. doi: 10.1021/jacs.8b04681. Epub 2018 Aug 23.

PMID:
30085664
18.

Interactions of bacteriophage T4 adhesin with selected lipopolysaccharides studied using atomic force microscopy.

Brzozowska E, Leśniewski A, Sęk S, Wieneke R, Tampé R, Górska S, Jönsson-Niedziółka M, Niedziółka-Jönsson J.

Sci Rep. 2018 Jul 19;8(1):10935. doi: 10.1038/s41598-018-29383-w.

19.

The Scaffold Design of Trivalent Chelator Heads Dictates Affinity and Stability for Labeling His-tagged Proteins in vitro and in Cells.

Gatterdam K, Joest EF, Gatterdam V, Tampé R.

Angew Chem Int Ed Engl. 2018 Sep 17;57(38):12395-12399. doi: 10.1002/anie.201802746. Epub 2018 Jun 26.

PMID:
29845721
20.

Moving the Cellular Peptidome by Transporters.

Abele R, Tampé R.

Front Cell Dev Biol. 2018 Apr 30;6:43. doi: 10.3389/fcell.2018.00043. eCollection 2018. Review.

21.

Transparent Nanopore Cavity Arrays Enable Highly Parallelized Optical Studies of Single Membrane Proteins on Chip.

Diederichs T, Nguyen QH, Urban M, Tampé R, Tornow M.

Nano Lett. 2018 Jun 13;18(6):3901-3910. doi: 10.1021/acs.nanolett.8b01252. Epub 2018 May 14.

PMID:
29741381
22.

Multifaceted structures and mechanisms of ABC transport systems in health and disease.

Thomas C, Tampé R.

Curr Opin Struct Biol. 2018 Aug;51:116-128. doi: 10.1016/j.sbi.2018.03.016. Epub 2018 Apr 9. Review.

PMID:
29635113
23.

Enhanced labeling density and whole-cell 3D dSTORM imaging by repetitive labeling of target proteins.

Venkataramani V, Kardorff M, Herrmannsdörfer F, Wieneke R, Klein A, Tampé R, Heilemann M, Kuner T.

Sci Rep. 2018 Apr 3;8(1):5507. doi: 10.1038/s41598-018-23818-0.

24.

Interaction of von Willebrand factor domains with collagen investigated by single molecule force spectroscopy.

Posch S, Obser T, König G, Schneppenheim R, Tampé R, Hinterdorfer P.

J Chem Phys. 2018 Mar 28;148(12):123310. doi: 10.1063/1.5007313.

PMID:
29604837
25.

Antitumor activity and carrier properties of novel hemocyanins coupled to a mimotope of GD2 ganglioside.

Palacios M, Tampe R, Del Campo M, Zhong TY, López MN, Salazar-Onfray F, Becker MI.

Eur J Med Chem. 2018 Apr 25;150:74-86. doi: 10.1016/j.ejmech.2018.02.082. Epub 2018 Feb 27.

PMID:
29524730
26.

Super-Chelators for Advanced Protein Labeling in Living Cells.

Gatterdam K, Joest EF, Dietz MS, Heilemann M, Tampé R.

Angew Chem Int Ed Engl. 2018 May 14;57(20):5620-5625. doi: 10.1002/anie.201800827. Epub 2018 Apr 14.

PMID:
29464841
27.

Dynamic blue light-switchable protein patterns on giant unilamellar vesicles.

Bartelt SM, Chervyachkova E, Steinkühler J, Ricken J, Wieneke R, Tampé R, Dimova R, Wegner SV.

Chem Commun (Camb). 2018 Jan 23;54(8):948-951. doi: 10.1039/c7cc08758f.

PMID:
29319072
28.

Conformational Coupling and trans-Inhibition in the Human Antigen Transporter Ortholog TmrAB Resolved with Dipolar EPR Spectroscopy.

Barth K, Hank S, Spindler PE, Prisner TF, Tampé R, Joseph B.

J Am Chem Soc. 2018 Apr 4;140(13):4527-4533. doi: 10.1021/jacs.7b12409. Epub 2018 Jan 30.

PMID:
29308886
29.

Structure of the human MHC-I peptide-loading complex.

Blees A, Januliene D, Hofmann T, Koller N, Schmidt C, Trowitzsch S, Moeller A, Tampé R.

Nature. 2017 Nov 23;551(7681):525-528. doi: 10.1038/nature24627. Epub 2017 Nov 6.

PMID:
29107940
30.

Camptothecin and its analog SN-38, the active metabolite of irinotecan, inhibit binding of the transcriptional regulator and oncoprotein FUBP1 to its DNA target sequence FUSE.

Khageh Hosseini S, Kolterer S, Steiner M, von Manstein V, Gerlach K, Trojan J, Waidmann O, Zeuzem S, Schulze JO, Hahn S, Steinhilber D, Gatterdam V, Tampé R, Biondi RM, Proschak E, Zörnig M.

Biochem Pharmacol. 2017 Dec 15;146:53-62. doi: 10.1016/j.bcp.2017.10.003. Epub 2017 Oct 13.

PMID:
29031818
31.

Structure of the TAPBPR-MHC I complex defines the mechanism of peptide loading and editing.

Thomas C, Tampé R.

Science. 2017 Nov 24;358(6366):1060-1064. doi: 10.1126/science.aao6001. Epub 2017 Oct 12.

PMID:
29025996
32.

Structure of the 40S-ABCE1 post-splitting complex in ribosome recycling and translation initiation.

Heuer A, Gerovac M, Schmidt C, Trowitzsch S, Preis A, Kötter P, Berninghausen O, Becker T, Beckmann R, Tampé R.

Nat Struct Mol Biol. 2017 May;24(5):453-460. doi: 10.1038/nsmb.3396. Epub 2017 Apr 3.

PMID:
28368393
33.

Vapor Phase Exchange of Self-Assembled Monolayers for Engineering of Biofunctional Surfaces.

Kankate L, Aguf A, Großmann H, Schnietz M, Tampé R, Turchanin A, Gölzhäuser A.

Langmuir. 2017 Apr 18;33(15):3847-3854. doi: 10.1021/acs.langmuir.6b04207. Epub 2017 Apr 3.

PMID:
28340533
34.

Proofreading of Peptide-MHC Complexes through Dynamic Multivalent Interactions.

Thomas C, Tampé R.

Front Immunol. 2017 Feb 8;8:65. doi: 10.3389/fimmu.2017.00065. eCollection 2017. Review.

35.

Structure and Dynamics of Antigenic Peptides in Complex with TAP.

Lehnert E, Tampé R.

Front Immunol. 2017 Jan 30;8:10. doi: 10.3389/fimmu.2017.00010. eCollection 2017. Review.

36.

Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP.

Nöll A, Thomas C, Herbring V, Zollmann T, Barth K, Mehdipour AR, Tomasiak TM, Brüchert S, Joseph B, Abele R, Oliéric V, Wang M, Diederichs K, Hummer G, Stroud RM, Pos KM, Tampé R.

Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E438-E447. doi: 10.1073/pnas.1620009114. Epub 2017 Jan 9.

37.

Coupled ATPase-adenylate kinase activity in ABC transporters.

Kaur H, Lakatos-Karoly A, Vogel R, Nöll A, Tampé R, Glaubitz C.

Nat Commun. 2016 Dec 22;7:13864. doi: 10.1038/ncomms13864.

38.

Nanomolar affinity protein trans-splicing monitored in real-time by fluorophore-quencher pairs.

Braner M, Wieneke R, Tampé R.

Chem Commun (Camb). 2017 Jan 3;53(3):545-548. doi: 10.1039/c6cc08862g.

PMID:
27966705
39.

Sublethal doses of dinophysistoxin-1 and okadaic acid stimulate secretion of inflammatory factors on innate immune cells: Negative health consequences.

Del Campo M, Zhong TY, Tampe R, García L, Lagos N.

Toxicon. 2017 Feb;126:23-31. doi: 10.1016/j.toxicon.2016.12.005. Epub 2016 Dec 9.

PMID:
27956244
40.

A dual inhibition mechanism of herpesviral ICP47 arresting a conformationally thermostable TAP complex.

Herbring V, Bäucker A, Trowitzsch S, Tampé R.

Sci Rep. 2016 Nov 15;6:36907. doi: 10.1038/srep36907.

41.

Structure of the ribosome post-recycling complex probed by chemical cross-linking and mass spectrometry.

Kiosze-Becker K, Ori A, Gerovac M, Heuer A, Nürenberg-Goloub E, Rashid UJ, Becker T, Beckmann R, Beck M, Tampé R.

Nat Commun. 2016 Nov 8;7:13248. doi: 10.1038/ncomms13248.

42.

Antigenic Peptide Recognition on the Human ABC Transporter TAP Resolved by DNP-Enhanced Solid-State NMR Spectroscopy.

Lehnert E, Mao J, Mehdipour AR, Hummer G, Abele R, Glaubitz C, Tampé R.

J Am Chem Soc. 2016 Oct 26;138(42):13967-13974. doi: 10.1021/jacs.6b07426. Epub 2016 Oct 17.

PMID:
27659210
43.

Single-molecule FRET reveals the pre-initiation and initiation conformations of influenza virus promoter RNA.

Robb NC, Te Velthuis AJ, Wieneke R, Tampé R, Cordes T, Fodor E, Kapanidis AN.

Nucleic Acids Res. 2016 Dec 1;44(21):10304-10315. Epub 2016 Sep 30.

44.

EB1 interacts with outwardly curved and straight regions of the microtubule lattice.

Guesdon A, Bazile F, Buey RM, Mohan R, Monier S, García RR, Angevin M, Heichette C, Wieneke R, Tampé R, Duchesne L, Akhmanova A, Steinmetz MO, Chrétien D.

Nat Cell Biol. 2016 Oct;18(10):1102-8. doi: 10.1038/ncb3412. Epub 2016 Sep 12.

PMID:
27617931
45.

EIGER detector: application in macromolecular crystallography.

Casanas A, Warshamanage R, Finke AD, Panepucci E, Olieric V, Nöll A, Tampé R, Brandstetter S, Förster A, Mueller M, Schulze-Briese C, Bunk O, Wang M.

Acta Crystallogr D Struct Biol. 2016 Sep;72(Pt 9):1036-48. doi: 10.1107/S2059798316012304. Epub 2016 Aug 31.

46.

Membrane Transport Processes Analyzed by a Highly Parallel Nanopore Chip System at Single Protein Resolution.

Urban M, Vor der Brüggen M, Tampé R.

J Vis Exp. 2016 Aug 16;(114). doi: 10.3791/53373.

47.

Single molecule force spectroscopy data and BD- and MD simulations on the blood protein von Willebrand factor.

Posch S, Aponte-Santamaría C, Schwarzl R, Karner A, Radtke M, Gräter F, Obser T, König G, Brehm MA, Gruber HJ, Netz RR, Baldauf C, Schneppenheim R, Tampé R, Hinterdorfer P.

Data Brief. 2016 Jul 21;8:1080-7. doi: 10.1016/j.dib.2016.07.031. eCollection 2016 Sep.

48.

Hemocyanins Stimulate Innate Immunity by Inducing Different Temporal Patterns of Proinflammatory Cytokine Expression in Macrophages.

Zhong TY, Arancibia S, Born R, Tampe R, Villar J, Del Campo M, Manubens A, Becker MI.

J Immunol. 2016 Jun 1;196(11):4650-62. doi: 10.4049/jimmunol.1501156. Epub 2016 Apr 22.

49.

Mutual A domain interactions in the force sensing protein von Willebrand factor.

Posch S, Aponte-Santamaría C, Schwarzl R, Karner A, Radtke M, Gräter F, Obser T, König G, Brehm MA, Gruber HJ, Netz RR, Baldauf C, Schneppenheim R, Tampé R, Hinterdorfer P.

J Struct Biol. 2017 Jan;197(1):57-64. doi: 10.1016/j.jsb.2016.04.012. Epub 2016 Apr 23.

50.

'Traceless' tracing of proteins - high-affinity trans-splicing directed by a minimal interaction pair.

Braner M, Kollmannsperger A, Wieneke R, Tampé R.

Chem Sci. 2016 Apr 21;7(4):2646-2652. doi: 10.1039/c5sc02936h. Epub 2015 Dec 21.

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