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Items: 15

1.

Comparison of in chemico skin sensitization methods and development of an in chemico skin photosensitization assay.

Patel NH, Mishra PK, Nagane R, Deshpande A, Tamboli IY, Date R.

ALTEX. 2019;36(3):373-387. doi: 10.14573/altex.1811011. Epub 2019 Mar 11.

2.

Trehalose Alters Subcellular Trafficking and the Metabolism of the Alzheimer-associated Amyloid Precursor Protein.

Tien NT, Karaca I, Tamboli IY, Walter J.

J Biol Chem. 2016 May 13;291(20):10528-40. doi: 10.1074/jbc.M116.719286. Epub 2016 Mar 8.

3.

Deficiency of sphingosine-1-phosphate lyase impairs lysosomal metabolism of the amyloid precursor protein.

Karaca I, Tamboli IY, Glebov K, Richter J, Fell LH, Grimm MO, Haupenthal VJ, Hartmann T, Gräler MH, van Echten-Deckert G, Walter J.

J Biol Chem. 2014 Jun 13;289(24):16761-72. doi: 10.1074/jbc.M113.535500. Epub 2014 May 7.

4.

Extracellular proteolysis of apolipoprotein E (apoE) by secreted serine neuronal protease.

Tamboli IY, Heo D, Rebeck GW.

PLoS One. 2014 Mar 27;9(3):e93120. doi: 10.1371/journal.pone.0093120. eCollection 2014.

5.

Human APOE genotype affects intraneuronal Aβ1-42 accumulation in a lentiviral gene transfer model.

Zhao W, Dumanis SB, Tamboli IY, Rodriguez GA, Jo Ladu M, Moussa CE, William Rebeck G.

Hum Mol Genet. 2014 Mar 1;23(5):1365-75. doi: 10.1093/hmg/ddt525. Epub 2013 Oct 23.

6.

Presenilin-1 L166P mutant human pluripotent stem cell-derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation.

Koch P, Tamboli IY, Mertens J, Wunderlich P, Ladewig J, Stüber K, Esselmann H, Wiltfang J, Brüstle O, Walter J.

Am J Pathol. 2012 Jun;180(6):2404-16. doi: 10.1016/j.ajpath.2012.02.012. Epub 2012 Apr 14.

PMID:
22510327
7.

Sphingolipid storage impairs autophagic clearance of Alzheimer-associated proteins.

Tamboli IY, Tien NT, Walter J.

Autophagy. 2011 Jun;7(6):645-6. Epub 2011 Jun 1.

PMID:
21460623
8.

Sphingolipid storage affects autophagic metabolism of the amyloid precursor protein and promotes Abeta generation.

Tamboli IY, Hampel H, Tien NT, Tolksdorf K, Breiden B, Mathews PM, Saftig P, Sandhoff K, Walter J.

J Neurosci. 2011 Feb 2;31(5):1837-49. doi: 10.1523/JNEUROSCI.2954-10.2011.

9.

Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion.

Tamboli IY, Barth E, Christian L, Siepmann M, Kumar S, Singh S, Tolksdorf K, Heneka MT, Lütjohann D, Wunderlich P, Walter J.

J Biol Chem. 2010 Nov 26;285(48):37405-14. doi: 10.1074/jbc.M110.149468. Epub 2010 Sep 28.

10.

Histone deacetylase inhibitor valproic acid inhibits cancer cell proliferation via down-regulation of the alzheimer amyloid precursor protein.

Venkataramani V, Rossner C, Iffland L, Schweyer S, Tamboli IY, Walter J, Wirths O, Bayer TA.

J Biol Chem. 2010 Apr 2;285(14):10678-89. doi: 10.1074/jbc.M109.057836. Epub 2010 Feb 9.

11.

Adaptation of neuronal cells to chronic oxidative stress is associated with altered cholesterol and sphingolipid homeostasis and lysosomal function.

Clement AB, Gamerdinger M, Tamboli IY, Lütjohann D, Walter J, Greeve I, Gimpl G, Behl C.

J Neurochem. 2009 Nov;111(3):669-82. doi: 10.1111/j.1471-4159.2009.06360.x. Epub 2009 Aug 27.

12.

Presenilin 1 affects focal adhesion site formation and cell force generation via c-Src transcriptional and posttranslational regulation.

Waschbüsch D, Born S, Niediek V, Kirchgessner N, Tamboli IY, Walter J, Merkel R, Hoffmann B.

J Biol Chem. 2009 Apr 10;284(15):10138-49. doi: 10.1074/jbc.M806825200. Epub 2009 Jan 27.

13.

Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.

Tamboli IY, Prager K, Thal DR, Thelen KM, Dewachter I, Pietrzik CU, St George-Hyslop P, Sisodia SS, De Strooper B, Heneka MT, Filippov MA, Müller U, van Leuven F, Lütjohann D, Walter J.

J Neurosci. 2008 Nov 12;28(46):12097-106. doi: 10.1523/JNEUROSCI.2635-08.2008.

14.

Cerebral small vessel disease-induced apolipoprotein E leakage is associated with Alzheimer disease and the accumulation of amyloid beta-protein in perivascular astrocytes.

Utter S, Tamboli IY, Walter J, Upadhaya AR, Birkenmeier G, Pietrzik CU, Ghebremedhin E, Thal DR.

J Neuropathol Exp Neurol. 2008 Sep;67(9):842-56. doi: 10.1097/NEN.0b013e3181836a71.

PMID:
18716559
15.

Inhibition of glycosphingolipid biosynthesis reduces secretion of the beta-amyloid precursor protein and amyloid beta-peptide.

Tamboli IY, Prager K, Barth E, Heneka M, Sandhoff K, Walter J.

J Biol Chem. 2005 Jul 29;280(30):28110-7. Epub 2005 May 27.

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