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Items: 35


The Circadian Clock Protein CRY1 Is a Negative Regulator of HIF-1α.

Dimova EY, Jakupovic M, Kubaichuk K, Mennerich D, Chi TF, Tamanini F, Oklejewicz M, Hänig J, Byts N, Mäkelä KA, Herzig KH, Koivunen P, Chaves I, van der Horst G, Kietzmann T.

iScience. 2019 Mar 29;13:284-304. doi: 10.1016/j.isci.2019.02.027. Epub 2019 Mar 1.


Loss-of-function mutations in ADCY3 cause monogenic severe obesity.

Saeed S, Bonnefond A, Tamanini F, Mirza MU, Manzoor J, Janjua QM, Din SM, Gaitan J, Milochau A, Durand E, Vaillant E, Haseeb A, De Graeve F, Rabearivelo I, Sand O, Queniat G, Boutry R, Schott DA, Ayesha H, Ali M, Khan WI, Butt TA, Rinne T, Stumpel C, Abderrahmani A, Lang J, Arslan M, Froguel P.

Nat Genet. 2018 Feb;50(2):175-179. doi: 10.1038/s41588-017-0023-6. Epub 2018 Jan 8.


Colorectal liver metastases with a disrupted circadian rhythm phase shift the peripheral clock in liver and kidney.

Huisman SA, Oklejewicz M, Ahmadi AR, Tamanini F, Ijzermans JN, van der Horst GT, de Bruin RW.

Int J Cancer. 2015 Mar 1;136(5):1024-32. doi: 10.1002/ijc.29089. Epub 2014 Aug 4.


Phase locking and multiple oscillating attractors for the coupled mammalian clock and cell cycle.

Feillet C, Krusche P, Tamanini F, Janssens RC, Downey MJ, Martin P, Teboul M, Saito S, Lévi FA, Bretschneider T, van der Horst GT, Delaunay F, Rand DA.

Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):9828-33. doi: 10.1073/pnas.1320474111. Epub 2014 Jun 23.


Altered phase-relationship between peripheral oscillators and environmental time in Cry1 or Cry2 deficient mouse models for early and late chronotypes.

Destici E, Jacobs EH, Tamanini F, Loos M, van der Horst GT, Oklejewicz M.

PLoS One. 2013 Dec 26;8(12):e83602. doi: 10.1371/journal.pone.0083602. eCollection 2013.


Mammalian TIMELESS is involved in period determination and DNA damage-dependent phase advancing of the circadian clock.

Engelen E, Janssens RC, Yagita K, Smits VA, van der Horst GT, Tamanini F.

PLoS One. 2013;8(2):e56623. doi: 10.1371/journal.pone.0056623. Epub 2013 Feb 13.


Histone methyltransferase MLL3 contributes to genome-scale circadian transcription.

Valekunja UK, Edgar RS, Oklejewicz M, van der Horst GT, O'Neill JS, Tamanini F, Turner DJ, Reddy AB.

Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1554-9. doi: 10.1073/pnas.1214168110. Epub 2013 Jan 7.


Flexible phase adjustment of circadian albumin D site-binding protein (DBP) gene expression by CRYPTOCHROME1.

Stratmann M, Stadler F, Tamanini F, van der Horst GT, Ripperger JA.

Genes Dev. 2010 Jun 15;24(12):1317-28. doi: 10.1101/gad.578810.


Impact of the circadian clock on in vitro genotoxic risk assessment assays.

Destici E, Oklejewicz M, Nijman R, Tamanini F, van der Horst GT.

Mutat Res. 2009 Nov-Dec;680(1-2):87-94. doi: 10.1016/j.mrgentox.2009.09.001. Epub 2009 Sep 12. Review.


Fragile X-related proteins regulate mammalian circadian behavioral rhythms.

Zhang J, Fang Z, Jud C, Vansteensel MJ, Kaasik K, Lee CC, Albrecht U, Tamanini F, Meijer JH, Oostra BA, Nelson DL.

Am J Hum Genet. 2008 Jul;83(1):43-52. doi: 10.1016/j.ajhg.2008.06.003. Epub 2008 Jun 26.


Structure function analysis of mammalian cryptochromes.

Tamanini F, Chaves I, Bajek MI, van der Horst GT.

Cold Spring Harb Symp Quant Biol. 2007;72:133-9. doi: 10.1101/sqb.2007.72.066. Review.


Phase resetting of the mammalian circadian clock by DNA damage.

Oklejewicz M, Destici E, Tamanini F, Hut RA, Janssens R, van der Horst GT.

Curr Biol. 2008 Feb 26;18(4):286-91. doi: 10.1016/j.cub.2008.01.047.


Light entrainment of the mammalian circadian clock by a PRKCA-dependent posttranslational mechanism.

Jakubcakova V, Oster H, Tamanini F, Cadenas C, Leitges M, van der Horst GT, Eichele G.

Neuron. 2007 Jun 7;54(5):831-43.


Manipulation of mammalian cell lines for circadian studies.

Tamanini F.

Methods Mol Biol. 2007;362:443-53.


The BMAL1 C terminus regulates the circadian transcription feedback loop.

Kiyohara YB, Tagao S, Tamanini F, Morita A, Sugisawa Y, Yasuda M, Yamanaka I, Ueda HR, van der Horst GT, Kondo T, Yagita K.

Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):10074-9. Epub 2006 Jun 15.


Functional evolution of the photolyase/cryptochrome protein family: importance of the C terminus of mammalian CRY1 for circadian core oscillator performance.

Chaves I, Yagita K, Barnhoorn S, Okamura H, van der Horst GT, Tamanini F.

Mol Cell Biol. 2006 Mar;26(5):1743-53.


Nucleocytoplasmic shuttling of clock proteins.

Tamanini F, Yagita K, Okamura H, van der Horst GT.

Methods Enzymol. 2005;393:418-35.


Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein.

Yagita K, Tamanini F, Yasuda M, Hoeijmakers JH, van der Horst GT, Okamura H.

EMBO J. 2002 Mar 15;21(6):1301-14.


Molecular mechanisms of the biological clock in cultured fibroblasts.

Yagita K, Tamanini F, van Der Horst GT, Okamura H.

Science. 2001 Apr 13;292(5515):278-81.


The fragile X-related proteins FXR1P and FXR2P contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins.

Tamanini F, Kirkpatrick LL, Schonkeren J, van Unen L, Bontekoe C, Bakker C, Nelson DL, Galjaard H, Oostra BA, Hoogeveen AT.

Hum Mol Genet. 2000 Jun 12;9(10):1487-93.


Dimerization and nuclear entry of mPER proteins in mammalian cells.

Yagita K, Yamaguchi S, Tamanini F, van Der Horst GT, Hoeijmakers JH, Yasui A, Loros JJ, Dunlap JC, Okamura H.

Genes Dev. 2000 Jun 1;14(11):1353-63.


Oligomerization properties of fragile-X mental-retardation protein (FMRP) and the fragile-X-related proteins FXR1P and FXR2P.

Tamanini F, Van Unen L, Bakker C, Sacchi N, Galjaard H, Oostra BA, Hoogeveen AT.

Biochem J. 1999 Nov 1;343 Pt 3:517-23.


Different targets for the fragile X-related proteins revealed by their distinct nuclear localizations.

Tamanini F, Bontekoe C, Bakker CE, van Unen L, Anar B, Willemsen R, Yoshida M, Galjaard H, Oostra BA, Hoogeveen AT.

Hum Mol Genet. 1999 May;8(5):863-9.


Subcellular localization of the oncoprotein MTG8 (CDR/ETO) in neural cells.

Sacchi N, Tamanini F, Willemsen R, Denis-Donini S, Campiglio S, Hoogeveen AT.

Oncogene. 1998 May;16(20):2609-15.


Mutations in GDI1 are responsible for X-linked non-specific mental retardation.

D'Adamo P, Menegon A, Lo Nigro C, Grasso M, Gulisano M, Tamanini F, Bienvenu T, Gedeon AK, Oostra B, Wu SK, Tandon A, Valtorta F, Balch WE, Chelly J, Toniolo D.

Nat Genet. 1998 Jun;19(2):134-9. Erratum in: Nat Genet 1998 Jul;19(3):303.


Differential expression of FMR1, FXR1 and FXR2 proteins in human brain and testis.

Tamanini F, Willemsen R, van Unen L, Bontekoe C, Galjaard H, Oostra BA, Hoogeveen AT.

Hum Mol Genet. 1997 Aug;6(8):1315-22.


Association of FMRP with ribosomal precursor particles in the nucleolus.

Willemsen R, Bontekoe C, Tamanini F, Galjaard H, Hoogeveen A, Oostra B.

Biochem Biophys Res Commun. 1996 Aug 5;225(1):27-33.


FMRP is associated to the ribosomes via RNA.

Tamanini F, Meijer N, Verheij C, Willems PJ, Galjaard H, Oostra BA, Hoogeveen AT.

Hum Mol Genet. 1996 Jun;5(6):809-13.


A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor.

Maestrini E, Tamagnone L, Longati P, Cremona O, Gulisano M, Bione S, Tamanini F, Neel BG, Toniolo D, Comoglio PM.

Proc Natl Acad Sci U S A. 1996 Jan 23;93(2):674-8.


A comparative transcriptional map of a region of 250 kb on the human and mouse X chromosome between the G6PD and the FLN1 genes.

Rivella S, Tamanini F, Bione S, Mancini M, Herman G, Chatterjee A, Maestrini E, Toniolo D.

Genomics. 1995 Aug 10;28(3):377-82.


Transcriptional organization of a 450-kb region of the human X chromosome in Xq28.

Bione S, Tamanini F, Maestrini E, Tribioli C, Poustka A, Torri G, Rivella S, Toniolo D.

Proc Natl Acad Sci U S A. 1993 Dec 1;90(23):10977-81.


An archipelago of CpG islands in Xq28: identification and fine mapping of 20 new CpG islands of the human X chromosome.

Maestrini E, Tamanini F, Kioschis P, Gimbo E, Marinelli P, Tribioli C, D'Urso M, Palmieri G, Poustka A, Toniolo D.

Hum Mol Genet. 1992 Jul;1(4):275-80.


Identification and characterization of a new gene in the human Xq28 region.

van den Ouweland AM, Kioschis P, Verdijk M, Tamanini F, Toniolo D, Poustka A, van Oost BA.

Hum Mol Genet. 1992 Jul;1(4):269-73.


Methylation and sequence analysis around EagI sites: identification of 28 new CpG islands in XQ24-XQ28.

Tribioli C, Tamanini F, Patrosso C, Milanesi L, Villa A, Pergolizzi R, Maestrini E, Rivella S, Bione S, Mancini M, et al.

Nucleic Acids Res. 1992 Feb 25;20(4):727-33.

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