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Items: 1 to 50 of 233

1.

TALEN-Based Chemically Inducible, Dimerization-Dependent, Sequence-Specific Nucleases.

Matsumoto D, Tamamura H, Nomura W.

Biochemistry. 2019 Oct 21. doi: 10.1021/acs.biochem.9b00798. [Epub ahead of print]

PMID:
31603654
2.

Proton Beam Therapy for Histologically or Clinically Diagnosed Stage I Non-small Cell Lung Cancer (NSCLC): The First Nationwide Retrospective Study in Japan.

Ohnishi K, Nakamura N, Harada H, Tokumaru S, Wada H, Arimura T, Iwata H, Sato Y, Sekino Y, Tamamura H, Mizoe JE, Ogino T, Ishikawa H, Kikuchi Y, Okimoto T, Murayama S, Akimoto T, Sakurai H.

Int J Radiat Oncol Biol Phys. 2019 Sep 30. pii: S0360-3016(19)33837-4. doi: 10.1016/j.ijrobp.2019.09.013. [Epub ahead of print]

3.

Discovery and Development of Anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication.

Maeda K, Das D, Kobayakawa T, Tamamura H, Takeuchi H.

Curr Top Med Chem. 2019;19(18):1621-1649. doi: 10.2174/1568026619666190712204603.

PMID:
31424371
4.

Clinical Results of Proton Beam Therapy for Esophageal Cancer: Multicenter Retrospective Study in Japan.

Ono T, Wada H, Ishikawa H, Tamamura H, Tokumaru S.

Cancers (Basel). 2019 Jul 16;11(7). pii: E993. doi: 10.3390/cancers11070993.

5.

Efficacy of Endoscopic Evaluation of Acute Radiation Esophagitis during Chemoradiotherapy with Proton Beam Therapy Boost for Esophageal Cancer.

Hasatani K, Tamamura H, Yamamoto K, Aoyagi H, Miyanaga T, Kaizaki Y, Sawada T.

Digestion. 2019 May 8:1-9. doi: 10.1159/000500039. [Epub ahead of print]

6.

Dimeric C34 Derivatives Linked through Disulfide Bridges as New HIV-1 Fusion Inhibitors.

Kobayakawa T, Ebihara K, Honda Y, Fujino M, Nomura W, Yamamoto N, Murakami T, Tamamura H.

Chembiochem. 2019 Aug 16;20(16):2101-2108. doi: 10.1002/cbic.201900187. Epub 2019 Jul 4.

PMID:
31012222
7.

Development of a NanoBRET-Based Sensitive Screening Method for CXCR4 Ligands.

Sakyiamah MM, Nomura W, Kobayakawa T, Tamamura H.

Bioconjug Chem. 2019 May 15;30(5):1442-1450. doi: 10.1021/acs.bioconjchem.9b00182. Epub 2019 Apr 11.

PMID:
30973227
8.

Design, synthesis and biological evaluation of low molecular weight CXCR4 ligands.

Sakyiamah MM, Kobayakawa T, Fujino M, Konno M, Narumi T, Tanaka T, Nomura W, Yamamoto N, Murakami T, Tamamura H.

Bioorg Med Chem. 2019 Mar 15;27(6):1130-1138. doi: 10.1016/j.bmc.2019.02.013. Epub 2019 Feb 6.

PMID:
30772128
9.

Soluble-type small-molecule CD4 mimics as HIV entry inhibitors.

Kobayakawa T, Konno K, Ohashi N, Takahashi K, Masuda A, Yoshimura K, Harada S, Tamamura H.

Bioorg Med Chem Lett. 2019 Mar 1;29(5):719-723. doi: 10.1016/j.bmcl.2019.01.011. Epub 2019 Jan 11.

PMID:
30665681
10.

Erratum: Shibata S.; et al. Proton Beam Therapy without Fiducial Markers Using Four-Dimensional CT Planning for Large Hepatocellular Carcinomas. Cancers 2018, 10, 71.

Shibata S, Takamatsu S, Yamamoto K, Mizuhata M, Bou S, Sato Y, Kawamura M, Asahi S, Tameshige Y, Maeda Y, Sasaki M, Kumano T, Kobayashi S, Tamamura H, Gabata T.

Cancers (Basel). 2018 Dec 11;10(12). pii: E508. doi: 10.3390/cancers10120508.

11.

Comparison Between Stereotactic Radiotherapy and Sublobar Resection for Non-Small Cell Lung Cancer.

Tamura M, Matsumoto I, Tanaka Y, Saito D, Yoshida S, Kakegawa S, Kumano T, Shimizu Y, Tamamura H, Takanaka T, Takemura H.

Ann Thorac Surg. 2019 May;107(5):1544-1550. doi: 10.1016/j.athoracsur.2018.10.015. Epub 2018 Nov 17.

PMID:
30458155
12.

A clickable caging group as a new platform for modular caged compounds with improved photochemical properties.

Suzuki AZ, Sekine R, Takeda S, Aikawa R, Shiraishi Y, Hamaguchi T, Okuno H, Tamamura H, Furuta T.

Chem Commun (Camb). 2019 Jan 3;55(4):451-454. doi: 10.1039/c8cc07981a.

PMID:
30451249
13.

Benzolactam-related compounds promote apoptosis of HIV-infected human cells via protein kinase C-induced HIV latency reversal.

Matsuda K, Kobayakawa T, Tsuchiya K, Hattori SI, Nomura W, Gatanaga H, Yoshimura K, Oka S, Endo Y, Tamamura H, Mitsuya H, Maeda K.

J Biol Chem. 2019 Jan 4;294(1):116-129. doi: 10.1074/jbc.RA118.005798. Epub 2018 Nov 9.

14.

Inhibition of EGFR Activation by Bivalent Ligands Based on a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR.

Toyama K, Kobayakawa T, Nomura W, Tamamura H.

Chem Pharm Bull (Tokyo). 2018;66(11):1083-1089. doi: 10.1248/cpb.c18-00539.

15.

Flexibility of small molecular CD4 mimics as HIV entry inhibitors.

Kobayakawa T, Ohashi N, Hirota Y, Takahashi K, Yamada Y, Narumi T, Yoshimura K, Matsushita S, Harada S, Tamamura H.

Bioorg Med Chem. 2018 Nov 15;26(21):5664-5671. doi: 10.1016/j.bmc.2018.10.011. Epub 2018 Oct 16.

PMID:
30366786
16.

Efficient and Orthogonal Transcription Regulation by Chemically Inducible Artificial Transcription Factors.

Nomura W, Matsumoto D, Sugii T, Kobayakawa T, Tamamura H.

Biochemistry. 2018 Nov 13;57(45):6452-6459. doi: 10.1021/acs.biochem.8b00741. Epub 2018 Nov 2.

PMID:
30366497
17.

Segmental analysis of respiratory liver motion in patients with and without a history of abdominal surgery.

Shimizu Y, Takamatsu S, Yamamoto K, Maeda Y, Sasaki M, Tamamura H, Bou S, Kumano T, Gabata T.

Jpn J Radiol. 2018 Aug;36(8):511-518. doi: 10.1007/s11604-018-0750-3. Epub 2018 Jun 20.

PMID:
29922899
18.

Delivery of a Proapoptotic Peptide to EGFR-Positive Cancer Cells by a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR.

Toyama K, Nomura W, Kobayakawa T, Tamamura H.

Bioconjug Chem. 2018 Jun 20;29(6):2050-2057. doi: 10.1021/acs.bioconjchem.8b00250. Epub 2018 May 31.

PMID:
29763296
19.

Effects of organ motion on proton prostate treatments, as determined from analysis of daily CT imaging for patient positioning.

Maeda Y, Sato Y, Shibata S, Bou S, Yamamoto K, Tamamura H, Fuwa N, Takamatsu S, Sasaki M, Tameshige Y, Kume K, Minami H, Saga Y, Saito M.

Med Phys. 2018 May;45(5):1844-1856. doi: 10.1002/mp.12869. Epub 2018 Apr 10.

PMID:
29574901
20.

Proton Beam Therapy without Fiducial Markers Using Four-Dimensional CT Planning for Large Hepatocellular Carcinomas.

Shibata S, Takamatsu S, Yamamoto K, Mizuhata M, Bou S, Sato Y, Kawamura M, Asahi S, Tameshige Y, Maeda Y, Sasaki M, Kumano T, Kobayashi S, Tamamura H, Gabata T.

Cancers (Basel). 2018 Mar 14;10(3). pii: E71. doi: 10.3390/cancers10030071. Erratum in: Cancers (Basel). 2018 Dec 11;10(12):.

21.

Positioning accuracy and daily dose assessment for prostate cancer treatment using in-room CT image guidance at a proton therapy facility.

Maeda Y, Sato Y, Minami H, Yasukawa Y, Yamamoto K, Tamamura H, Shibata S, Bou S, Sasaki M, Tameshige Y, Kume K, Ooto H, Kasahara S, Shimizu Y, Saga Y, Omoya A, Saitou M.

Med Phys. 2018 May;45(5):1832-1843. doi: 10.1002/mp.12858. Epub 2018 Apr 1.

PMID:
29532489
22.

Respiratory-gated Proton Beam Therapy for Hepatocellular Carcinoma Adjacent to the Gastrointestinal Tract without Fiducial Markers.

Mizuhata M, Takamatsu S, Shibata S, Bou S, Sato Y, Kawamura M, Asahi S, Tameshige Y, Maeda Y, Sasaki M, Kumano T, Kobayashi S, Yamamoto K, Tamamura H, Gabata T.

Cancers (Basel). 2018 Feb 21;10(2). pii: E58. doi: 10.3390/cancers10020058.

23.

Synthesis of a Chloroalkene Dipeptide Isostere-Containing Peptidomimetic and Its Biological Application.

Kobayakawa T, Matsuzaki Y, Hozumi K, Nomura W, Nomizu M, Tamamura H.

ACS Med Chem Lett. 2017 Dec 27;9(1):6-10. doi: 10.1021/acsmedchemlett.7b00234. eCollection 2018 Jan 11.

24.

Synthesis and Evaluation of Dimeric Derivatives of Diacylglycerol-Lactones as Protein Kinase C Ligands.

Ohashi N, Kobayashi R, Nomura W, Kobayakawa T, Czikora A, Herold BK, Lewin NE, Blumberg PM, Tamamura H.

Bioconjug Chem. 2017 Aug 16;28(8):2135-2144. doi: 10.1021/acs.bioconjchem.7b00299. Epub 2017 Jul 21.

PMID:
28671468
25.

Development of the breast immobilization system in prone setup: The effect of bra in prone position to improve the breast setup error.

Kawamura M, Maeda Y, Yamamoto K, Takamatsu S, Sato Y, Minami H, Saga Y, Kume K, Tameshige Y, Sasaki M, Tamamura H, Ohta K, Itoh Y, Naganawa S.

J Appl Clin Med Phys. 2017 Jul;18(4):155-160. doi: 10.1002/acm2.12116. Epub 2017 Jun 8.

26.

Effects of replacement and addition of an amino acid contained in a cyclic peptide corresponding to a β-hairpin loop sequence of human EGF receptor.

Kobayashi K, Mizuguchi T, Hattori Y, Ohara N, Ninomiya R, Iida M, Ooe H, Yamazaki Y, Takata M, Tamamura H, Akaji K.

J Pept Sci. 2017 Jul;23(7-8):581-586. doi: 10.1002/psc.3004. Epub 2017 Apr 4.

PMID:
28378383
27.

Microwave-Assisted Synthesis of Azacoumarin Fluorophores and the Fluorescence Characterization.

Takano H, Narumi T, Nomura W, Tamamura H.

J Org Chem. 2017 Mar 3;82(5):2739-2744. doi: 10.1021/acs.joc.6b02656. Epub 2017 Feb 16.

PMID:
28150494
28.

[ZIP tag-probe system: A fluorescence imaging tool for intercellular proteins].

Nomura W, Tamamura H.

Seikagaku. 2017 Feb;89(1):115-20. Review. Japanese. No abstract available.

PMID:
29624972
29.

Bivalent 14-mer peptide ligands of CXCR4 with polyproline linkers with anti-chemotactic activity against Jurkat cells.

Tanaka T, Aoki T, Nomura W, Tamamura H.

J Pept Sci. 2017 Jul;23(7-8):574-580. doi: 10.1002/psc.2946. Epub 2017 Jan 12.

PMID:
28078743
30.

Clinical outcomes of stage I and IIA non-small cell lung cancer patients treated with stereotactic body radiotherapy using a real-time tumor-tracking radiotherapy system.

Katoh N, Soda I, Tamamura H, Takahashi S, Uchinami Y, Ishiyama H, Ota K, Inoue T, Onimaru R, Shibuya K, Hayakawa K, Shirato H.

Radiat Oncol. 2017 Jan 5;12(1):3. doi: 10.1186/s13014-016-0742-3.

31.

Development and validation of a cell-based assay system to assess human immunodeficiency virus type 1 integrase multimerization.

Nakamura T, Campbell JR, Moore AR, Otsu S, Aikawa H, Tamamura H, Mitsuya H.

J Virol Methods. 2016 Oct;236:196-206. doi: 10.1016/j.jviromet.2016.07.023. Epub 2016 Jul 26.

32.

Development of anti-HIV peptides based on a viral capsid protein.

Mizuguchi T, Ohashi N, Matsumoto D, Hashimoto C, Nomura W, Yamamoto N, Murakami T, Tamamura H.

Biopolymers. 2017 Jan;108(1). doi: 10.1002/bip.22920.

PMID:
27428649
33.

Functional evaluation of fluorescein-labeled derivatives of a peptide inhibitor of the EGF receptor dimerization.

Toyama K, Mizuguchi T, Nomura W, Tamamura H.

Bioorg Med Chem. 2016 Aug 15;24(16):3406-12. doi: 10.1016/j.bmc.2016.05.026. Epub 2016 May 20.

PMID:
27283787
34.

SDF-1 controls the muscle and blood vessel formation of the somite.

Abduelmula A, Huang R, Pu Q, Tamamura H, Morosan-Puopolo G, Brand-Saberi B.

Int J Dev Biol. 2016;60(1-3):29-38. doi: 10.1387/ijdb.150132rh.

35.

Small-Molecule CD4 Mimics Containing Mono-cyclohexyl Moieties as HIV Entry Inhibitors.

Ohashi N, Harada S, Mizuguchi T, Irahara Y, Yamada Y, Kotani M, Nomura W, Matsushita S, Yoshimura K, Tamamura H.

ChemMedChem. 2016 Apr 19;11(8):940-6. doi: 10.1002/cmdc.201500590. Epub 2016 Feb 17.

PMID:
26891461
36.

A minimally cytotoxic CD4 mimic as an HIV entry inhibitor.

Mizuguchi T, Harada S, Miura T, Ohashi N, Narumi T, Mori H, Irahara Y, Yamada Y, Nomura W, Matsushita S, Yoshimura K, Tamamura H.

Bioorg Med Chem Lett. 2016 Jan 15;26(2):397-400. doi: 10.1016/j.bmcl.2015.11.103. Epub 2015 Nov 30.

PMID:
26706175
37.

Multimerized HIV-gp41-derived peptides as fusion inhibitors and vaccines.

Nomura W, Mizuguchi T, Tamamura H.

Biopolymers. 2016 Nov 4;106(4):622-8. doi: 10.1002/bip.22782. Review.

PMID:
26583370
38.

Utilization of the Heavy Atom Effect for the Development of a Photosensitive 8-Azacoumarin-Type Photolabile Protecting Group.

Takano H, Narumi T, Nomura W, Furuta T, Tamamura H.

Org Lett. 2015 Nov 6;17(21):5372-5. doi: 10.1021/acs.orglett.5b02720. Epub 2015 Oct 15.

PMID:
26469518
39.

Exploration of labeling by near infrared dyes of the polyproline linker for bivalent-type CXCR4 ligands.

Nomura W, Aikawa H, Taketomi S, Tanabe M, Mizuguchi T, Tamamura H.

Bioorg Med Chem. 2015 Nov 1;23(21):6967-73. doi: 10.1016/j.bmc.2015.09.040. Epub 2015 Sep 28.

PMID:
26453409
40.

Trivalent ligands for CXCR4 bearing polyproline linkers show specific recognition for cells with increased CXCR4 expression.

Nomura W, Koseki T, Ohashi N, Mizuguchi T, Tamamura H.

Org Biomol Chem. 2015 Aug 28;13(32):8734-9. doi: 10.1039/c5ob00891c. Epub 2015 Jul 17.

PMID:
26186480
41.

Anti-HIV screening for cell-penetrating peptides using chloroquine and identification of anti-HIV peptides derived from matrix proteins.

Mizuguchi T, Ohashi N, Nomura W, Komoriya M, Hashimoto C, Yamamoto N, Murakami T, Tamamura H.

Bioorg Med Chem. 2015 Aug 1;23(15):4423-7. doi: 10.1016/j.bmc.2015.06.020. Epub 2015 Jun 15.

PMID:
26094944
42.

Remote Stereoinduction in the Organocuprate-Mediated Allylic Alkylation of Allylic gem-Dichlorides: Highly Diastereoselective Synthesis of (Z)-Chloroalkene Dipeptide Isosteres.

Kobayakawa T, Narumi T, Tamamura H.

Org Lett. 2015 May 15;17(10):2302-5. doi: 10.1021/acs.orglett.5b00611. Epub 2015 May 7.

PMID:
25950639
43.

An in-cell fluorogenic Tag-probe system for protein dynamics imaging enabled by cell-penetrating peptides.

Nomura W, Ohashi N, Mori A, Tamamura H.

Bioconjug Chem. 2015 Jun 17;26(6):1080-5. doi: 10.1021/acs.bioconjchem.5b00131. Epub 2015 May 15.

PMID:
25938941
44.

Screening for protein kinase C ligands using fluorescence resonance energy transfer.

Ohashi N, Nomura W, Minato N, Tamamura H.

Chem Pharm Bull (Tokyo). 2014;62(10):1019-25. Epub 2014 Aug 8.

45.

Retrograde migration of pectoral girdle muscle precursors depends on CXCR4/SDF-1 signaling.

Masyuk M, Abduelmula A, Morosan-Puopolo G, Ödemis V, Rehimi R, Khalida N, Yusuf F, Engele J, Tamamura H, Theiss C, Brand-Saberi B.

Histochem Cell Biol. 2014 Nov;142(5):473-88. doi: 10.1007/s00418-014-1237-7. Epub 2014 Jun 28.

PMID:
24972797
46.

Development of a traceable linker containing a thiol-responsive amino acid for the enrichment and selective labelling of target proteins.

Yamamoto J, Denda M, Maeda N, Kita M, Komiya C, Tanaka T, Nomura W, Tamamura H, Sato Y, Yamauchi A, Shigenaga A, Otaka A.

Org Biomol Chem. 2014 Jun 21;12(23):3821-6. doi: 10.1039/c4ob00622d.

PMID:
24806338
47.

Basaloid squamous cell carcinoma in the nasal cavity treated with proton beam therapy concurrent with cisplatin: a case report.

Takamatsu S, Yamamoto K, Kondou T, Kawamura M, Asahi S, Tameshige Y, Maeda Y, Sasaki M, Tamamura H, Tsuji A, Kaizaki Y, Kumano T, Takanaka T.

J Med Case Rep. 2014 Apr 9;8:123. doi: 10.1186/1752-1947-8-123.

48.

Isostere-based design of 8-azacoumarin-type photolabile protecting groups: a hydrophilicity-increasing strategy for coumarin-4-ylmethyls.

Narumi T, Takano H, Ohashi N, Suzuki A, Furuta T, Tamamura H.

Org Lett. 2014 Feb 21;16(4):1184-7. doi: 10.1021/ol5000583. Epub 2014 Feb 4.

PMID:
24495035
49.

A CD4 mimic as an HIV entry inhibitor: pharmacokinetics.

Hashimoto C, Narumi T, Otsuki H, Hirota Y, Arai H, Yoshimura K, Harada S, Ohashi N, Nomura W, Miura T, Igarashi T, Matsushita S, Tamamura H.

Bioorg Med Chem. 2013 Dec 15;21(24):7884-9. doi: 10.1016/j.bmc.2013.10.005. Epub 2013 Oct 17.

PMID:
24189188
50.

CXCR4-derived synthetic peptides inducing anti-HIV-1 antibodies.

Hashimoto C, Nomura W, Narumi T, Fujino M, Nakahara T, Yamamoto N, Murakami T, Tamamura H.

Bioorg Med Chem. 2013 Nov 15;21(22):6878-85. doi: 10.1016/j.bmc.2013.09.037. Epub 2013 Sep 21.

PMID:
24119449

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