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Items: 36

1.

Towards a combinatorial approach for the prediction of immunoglobulin G half-life and clearance.

Goulet DR, Watson MJ, Tam SH, Zwolak A, Chiu ML, Atkins WM, Nath A.

Drug Metab Dispos. 2018 Sep 19. pii: dmd.118.081893. doi: 10.1124/dmd.118.081893. [Epub ahead of print]

PMID:
30232177
2.

Rapid Purification of Human Bispecific Antibodies via Selective Modulation of Protein A Binding.

Zwolak A, Leettola CN, Tam SH, Goulet DR, Derebe MG, Pardinas JR, Zheng S, Decker R, Emmell E, Chiu ML.

Sci Rep. 2017 Nov 14;7(1):15521. doi: 10.1038/s41598-017-15748-0.

3.

Modulation of protein A binding allows single-step purification of mouse bispecific antibodies that retain FcRn binding.

Zwolak A, Armstrong AA, Tam SH, Pardinas JR, Goulet DR, Zheng S, Brosnan K, Emmell E, Luo J, Gilliland GL, Chiu ML.

MAbs. 2017 Nov/Dec;9(8):1306-1316. doi: 10.1080/19420862.2017.1375639. Epub 2017 Sep 12.

4.

Functional optimization of agonistic antibodies to OX40 receptor with novel Fc mutations to promote antibody multimerization.

Zhang D, Armstrong AA, Tam SH, McCarthy SG, Luo J, Gilliland GL, Chiu ML.

MAbs. 2017 Oct;9(7):1129-1142. doi: 10.1080/19420862.2017.1358838. Epub 2017 Jul 31.

5.

Medication Regimen Complexity in Long-Term Care Facilities and Adverse Drug Events-Related Hospitalizations.

Tam SHY, Hirsch JD, Watanabe JH.

Consult Pharm. 2017 May 1;32(5):281-284. doi: 10.4140/TCP.n.2017.281. Review.

PMID:
28483008
6.

Modification of the Fc Region of a Human Anti-oncostatin M Monoclonal Antibody for Higher Affinity to FcRn Receptor and Extension of Half-life in Cynomolgus Monkeys.

Nnane IP, Han C, Jiao Q, Tam SH, Davis HM, Xu Z.

Basic Clin Pharmacol Toxicol. 2017 Jul;121(1):13-21. doi: 10.1111/bcpt.12761. Epub 2017 Mar 8.

7.

Human and non-human primate intestinal FcRn expression and immunoglobulin G transcytosis.

Hornby PJ, Cooper PR, Kliwinski C, Ragwan E, Mabus JR, Harman B, Thompson S, Kauffman AL, Yan Z, Tam SH, Dorai H, Powers GD, Giles-Komar J.

Pharm Res. 2014 Apr;31(4):908-22. doi: 10.1007/s11095-013-1212-3. Epub 2013 Sep 26.

8.

Correlations between pharmacokinetics of IgG antibodies in primates vs. FcRn-transgenic mice reveal a rodent model with predictive capabilities.

Tam SH, McCarthy SG, Brosnan K, Goldberg KM, Scallon BJ.

MAbs. 2013 May-Jun;5(3):397-405. doi: 10.4161/mabs.23836. Epub 2013 Apr 2.

9.

Contribution of FcRn binding to intestinal uptake of IgG in suckling rat pups and human FcRn-transgenic mice.

Kliwinski C, Cooper PR, Perkinson R, Mabus JR, Tam SH, Wilkinson TM, Giles-Komar J, Scallon B, Powers GD, Hornby PJ.

Am J Physiol Gastrointest Liver Physiol. 2013 Feb 1;304(3):G262-70. doi: 10.1152/ajpgi.00340.2012. Epub 2012 Dec 6.

10.

Engineering host cell lines to reduce terminal sialylation of secreted antibodies.

Naso MF, Tam SH, Scallon BJ, Raju TS.

MAbs. 2010 Sep-Oct;2(5):519-27. doi: 10.4161/mabs.2.5.13078. Epub 2010 Sep 1.

11.

Tumor-associated and microbial proteases compromise host IgG effector functions by a single cleavage proximal to the hinge.

Brezski RJ, Vafa O, Petrone D, Tam SH, Powers G, Ryan MH, Luongo JL, Oberholtzer A, Knight DM, Jordan RE.

Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17864-9. doi: 10.1073/pnas.0904174106. Epub 2009 Oct 7.

12.

Human anti-IgG1 hinge autoantibodies reconstitute the effector functions of proteolytically inactivated IgGs.

Brezski RJ, Luongo JL, Petrone D, Ryan MH, Zhong D, Tam SH, Schmidt AP, Kruszynski M, Whitaker BP, Knight DM, Jordan RE.

J Immunol. 2008 Sep 1;181(5):3183-92.

13.

Expression of human tissue factor under the control of the mouse tissue factor promoter mediates normal hemostasis in knock-in mice.

Snyder LA, Rudnick KA, Tawadros R, Volk A, Tam SH, Anderson GM, Bugelski PJ, Yang J.

J Thromb Haemost. 2008 Feb;6(2):306-14. Epub 2007 Nov 14.

14.

Decreased threshold for the nitric oxide donor glyceryl trinitrate in cortisol-induced hypertension in humans.

Kelly JJ, Tam SH, Williamson PM, Whitworth JA.

Clin Exp Pharmacol Physiol. 2007 Dec;34(12):1317-8.

PMID:
17973874
15.

Interference with tissue factor prolongs intrahepatic islet allograft survival in a nonhuman primate marginal mass model.

Berman DM, Cabrera O, Kenyon NM, Miller J, Tam SH, Khandekar VS, Picha KM, Soderman AR, Jordan RE, Bugelski PJ, Horninger D, Lark M, Davis JE, Alejandro R, Berggren PO, Zimmerman M, O'Neil JJ, Ricordi C, Kenyon NS.

Transplantation. 2007 Aug 15;84(3):308-15.

PMID:
17700154
16.

CNTO 859, a humanized anti-tissue factor monoclonal antibody, is a potent inhibitor of breast cancer metastasis and tumor growth in xenograft models.

Ngo CV, Picha K, McCabe F, Millar H, Tawadros R, Tam SH, Nakada MT, Anderson GM.

Int J Cancer. 2007 Mar 15;120(6):1261-7.

17.

Higher levels of sialylated Fc glycans in immunoglobulin G molecules can adversely impact functionality.

Scallon BJ, Tam SH, McCarthy SG, Cai AN, Raju TS.

Mol Immunol. 2007 Mar;44(7):1524-34. Epub 2006 Oct 11.

PMID:
17045339
18.

Ganglion blockade does not prevent cortisol-induced hypertension in man.

Williamson PM, Tam SH, Kelly JJ, Whitworth JA.

Clin Exp Pharmacol Physiol. 2005 Apr;32(4):294-6.

PMID:
15810994
19.

Pharmacodynamic enhancement of the anti-platelet antibody fab abciximab by site-specific pegylation.

Knight DM, Jordan RE, Kruszynski M, Tam SH, Giles-Komar J, Treacy G, Heavner GA.

Platelets. 2004 Nov;15(7):409-18.

PMID:
15745312
20.

Abciximab pharmacodynamics are unaffected by antecedent therapy with other GPIIb/IIIa antagonists in non-human primates.

Nakada MT, Sassoli PM, Tam SH, Nedelman MA, Jordan RE, Kereiakes DJ.

J Thromb Thrombolysis. 2002 Aug;14(1):15-24.

PMID:
12652146
21.

7E3 F(ab')2, an effective antagonist of rat alphaIIbbeta3 and alphavbeta3, blocks in vivo thrombus formation and in vitro angiogenesis.

Sassoli PM, Emmell EL, Tam SH, Trikha M, Zhou Z, Jordan RE, Nakada MT.

Thromb Haemost. 2001 May;85(5):896-902.

PMID:
11372685
22.

The nitric oxide system and cortisol-induced hypertension in humans.

Kelly JJ, Tam SH, Williamson PM, Lawson J, Whitworth JA.

Clin Exp Pharmacol Physiol. 1998 Nov;25(11):945-6.

PMID:
9807669
23.

Neutralization of TNF by the antibody cA2 reveals differential regulation of adhesion molecule expression on TNF-activated endothelial cells.

Nakada MT, Tam SH, Woulfe DS, Casper KA, Swerlick RA, Ghrayeb J.

Cell Adhes Commun. 1998 Sep;5(6):491-503.

PMID:
9791729
24.
25.

Effects of diet on measurement of nitric oxide metabolites.

Wang J, Brown MA, Tam SH, Chan MC, Whitworth JA.

Clin Exp Pharmacol Physiol. 1997 Jun;24(6):418-20.

PMID:
9171946
26.

Reflex sympathetic function in cortisol-induced hypertension in humans.

Tam SH, Kelly JJ, Williamson PM, Whitworth JA.

Clin Exp Hypertens. 1997 May;19(4):479-93.

PMID:
9140709
27.

The role of the hypothalamic-pituitary-adrenal (HPA) axis in the regulation of blood pressure.

Phoon RK, Tam SH, Brown MA, Whitworth JA.

Clin Exp Hypertens. 1997 May;19(4):417-30.

PMID:
9140705
28.

Autonomic blockade amplifies cortisol-induced hypertension in man.

Tam SH, Williamson PM, Kelly JJ, Whitworth JA.

Clin Exp Pharmacol Physiol. 1997 Jan;24(1):31-3.

PMID:
9043802
29.

Structure-function studies on synthetic peptides derived from the 109-118 lectin domain of selectins.

Tam SH, Nakada MT, Kruszynski M, Fieles WE, Taylor AH, Mervic M, Heavner GA.

Biochem Biophys Res Commun. 1996 Oct 23;227(3):712-7.

PMID:
8885999
30.

Determination of the core sequence of an antagonist of selectin-dependent leukocyte adhesion and correlation of its structure with molecular modeling studies.

Kruszynski M, Nakada MT, Tam SH, Taylor AH, Fieles WE, Heavner GA.

Arch Biochem Biophys. 1996 Jul 1;331(1):23-30.

PMID:
8660679
31.

Antibiotics enhance binding by human lipid A-reactive monoclonal antibody HA-1A to smooth gram-negative bacteria.

Siegel SA, Evans ME, Pollack M, Leone AO, Kinney CS, Tam SH, Daddona PE.

Infect Immun. 1993 Feb;61(2):512-9.

32.

Labeling and stability of radiolabeled antibody fragments by a direct 99mTc-labeling method.

Pak KY, Nedelman MA, Tam SH, Wilson E, Daddona PE.

Int J Rad Appl Instrum B. 1992 Aug;19(6):669-77.

PMID:
1522021
33.

Evaluation of the 323/A3 monoclonal antibody and the use of technetium-99m-labeled 323/A3 Fab' for the detection of pan adenocarcinoma.

Pak KY, Nedelman MA, Fogler WE, Tam SH, Wilson E, Van Haarlem LJ, Colognola R, Warnaar SO, Daddona PE.

Int J Rad Appl Instrum B. 1991;18(5):483-97.

PMID:
1917518
34.

Expression in Escherichia coli of open reading frame gene segments of HTLV-III.

Chang NT, Chanda PK, Barone AD, McKinney S, Rhodes DP, Tam SH, Shearman CW, Huang J, Chang TW, Gallo RC, et al.

Science. 1985 Apr 5;228(4695):93-6.

PMID:
2983429
35.

A cDNA clone encoding a product of activated human T lymphocytes.

Chang NT, Tam SH, Kung PC, Chang TW.

Mol Biol Med. 1984 Apr;2(2):151-65.

PMID:
6335909
36.

Abundance, diversity, and regulation of mRNA sequence sets in soybean embryogenesis.

Goldberg RB, Hoschek G, Tam SH, Ditta GS, Breidenbach RW.

Dev Biol. 1981 Apr 30;83(2):201-17. No abstract available.

PMID:
6113179

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