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Factors Associated With a Higher Risk of Undiagnosed Prediabetes in a Community-Dwelling Medicare Population.

Valle-Oseguera CS, Ranson CA, Tam P, Le J, Le B, Kozono M, Park J, Tam A, Chen M, Rogan EL, Patel RA.

Sr Care Pharm. 2020 Feb 1;35(2):85-92. doi: 10.4140/TCP.n.2020.85.


Cellular diversity and lineage trajectory: insights from mouse single cell transcriptomes.

Tam PPL, Ho JWK.

Development. 2020 Jan 24;147(2). pii: dev179788. doi: 10.1242/dev.179788.


Laparoscopic surgical technique to enhance the management of anorectal malformations: 330 cases' experience in a single center.

Li L, Ren X, Ming A, Xu H, Sun R, Zhou Y, Liu X, Sun H, Li Q, Li X, Zhang Z, Cheng W, Diao M, Tam PKH.

Pediatr Surg Int. 2020 Mar;36(3):279-287. doi: 10.1007/s00383-019-04614-x. Epub 2020 Jan 9.


Author Correction: Molecular architecture of lineage allocation and tissue organization in early mouse embryo.

Peng G, Suo S, Cui G, Yu F, Wang R, Chen J, Chen S, Liu Z, Chen G, Qian Y, Tam PPL, Han JJ, Jing N.

Nature. 2020 Jan;577(7791):E6. doi: 10.1038/s41586-019-1887-7.


Transcriptional network dynamics during the progression of pluripotency revealed by integrative statistical learning.

Kim HJ, Osteil P, Humphrey SJ, Cinghu S, Oldfield AJ, Patrick E, Wilkie EE, Peng G, Suo S, Jothi R, Tam PPL, Yang P.

Nucleic Acids Res. 2019 Dec 19. pii: gkz1179. doi: 10.1093/nar/gkz1179. [Epub ahead of print]


Quality of life and defecative function 10 years or longer after posterior sagittal anorectoplasty and laparoscopic-assisted anorectal pull-through for anorectal malformation.

Wong CWY, Chung PHY, Tam PKH, Wong KKY.

Pediatr Surg Int. 2020 Mar;36(3):289-293. doi: 10.1007/s00383-019-04606-x. Epub 2019 Dec 17.


Associations between echocardiographic findings and prospective changes in residual renal function in patients new to peritoneal dialysis.

Mahdavi S, Yared K, Wu G, Omar B, Savundra D, Nagai G, Hockmann E, Svendrovski A, Bellasi A, Tam P, Sikaneta T.

Sci Rep. 2019 Dec 5;9(1):18434. doi: 10.1038/s41598-019-54851-2.


A Cohesin Subunit Variant Identified from a Peripheral Sclerocornea Pedigree.

Zhang BN, Chan TCY, Tam POS, Liu Y, Pang CP, Jhanji V, Chen LJ, Chu WK.

Dis Markers. 2019 Nov 12;2019:8781524. doi: 10.1155/2019/8781524. eCollection 2019.


Determining the optimal timing of liver transplant for pediatric patients after Kasai portoenterostomy based on disease severity scores.

Chung PHY, Chok KSH, Wong KKY, Tam PKH, Lo CM.

J Pediatr Surg. 2019 Nov 9. pii: S0022-3468(19)30751-1. doi: 10.1016/j.jpedsurg.2019.10.016. [Epub ahead of print]


Modeling the early development of a primate embryo.

Tam PPL.

Science. 2019 Nov 15;366(6467):798-799. doi: 10.1126/science.aaz6976. No abstract available.


Evaluation of the association of C5 with neovascular age-related macular degeneration and polypoidal choroidal vasculopathy.

Liu K, Ma L, Lai TYY, Brelen ME, Tam POS, Tham CC, Pang CP, Chen LJ.

Eye Vis (Lond). 2019 Nov 7;6:34. doi: 10.1186/s40662-019-0161-2. eCollection 2019.


Associations of Calcium from Food Sources Versus Phosphate Binders with Serum Calcium and FGF23 in Hemodialysis Patients.

Mahdavi S, Bellasi A, Nagra K, Johnston L, Tam P, Di Iorio B, Sikaneta T.

J Clin Med. 2019 Oct 14;8(10). pii: E1680. doi: 10.3390/jcm8101680.


An adolescent with multi-organ involvement from typhoid fever.

Kumwenda M, Tam PI.

Malawi Med J. 2019 Jun;31(2):159-160. doi: 10.4314/mmj.v31i2.10.


Ularcirc: visualization and enhanced analysis of circular RNAs via back and canonical forward splicing.

Humphreys DT, Fossat N, Demuth M, Tam PPL, Ho JWK.

Nucleic Acids Res. 2019 Nov 18;47(20):e123. doi: 10.1093/nar/gkz718.


Whole exome sequencing to uncover genetic variants underlying congenital cystic adenomatoid malformations.

Tam PK.

Hong Kong Med J. 2019 Aug;25 Suppl 5(4):36-38. No abstract available.


Molecular architecture of lineage allocation and tissue organization in early mouse embryo.

Peng G, Suo S, Cui G, Yu F, Wang R, Chen J, Chen S, Liu Z, Chen G, Qian Y, Tam PPL, Han JJ, Jing N.

Nature. 2019 Aug;572(7770):528-532. doi: 10.1038/s41586-019-1469-8. Epub 2019 Aug 7. Erratum in: Nature. 2020 Jan;577(7791):E6.


Identification and characterization of a novel promoter variant in placental growth factor for neovascular age-related macular degeneration.

Ma L, Ng TK, Chen H, Brelén ME, Lai TYY, Ho M, Tam POS, Young AL, Chen W, Tham CC, Pang CP, Chen LJ.

Exp Eye Res. 2019 Oct;187:107748. doi: 10.1016/j.exer.2019.107748. Epub 2019 Aug 1.


Association of the ZC3H11B, ZFHX1B and SNTB1 genes with myopia of different severities.

Tang SM, Li FF, Lu SY, Kam KW, Tam POS, Tham CC, Pang CP, Yam JCS, Chen LJ.

Br J Ophthalmol. 2019 Jul 12. pii: bjophthalmol-2019-314203. doi: 10.1136/bjophthalmol-2019-314203. [Epub ahead of print]


Coding Region Mutation Screening in Optineurin in Chinese Normal-Tension Glaucoma Patients.

He JN, Lu S, Chen LJ, Tam POS, Zhang BN, Leung CKS, Pang CP, Tham CCY, Chu WK.

Dis Markers. 2019 May 6;2019:5820537. doi: 10.1155/2019/5820537. eCollection 2019.


Establishment of porcine and human expanded potential stem cells.

Gao X, Nowak-Imialek M, Chen X, Chen D, Herrmann D, Ruan D, Chen ACH, Eckersley-Maslin MA, Ahmad S, Lee YL, Kobayashi T, Ryan D, Zhong J, Zhu J, Wu J, Lan G, Petkov S, Yang J, Antunes L, Campos LS, Fu B, Wang S, Yong Y, Wang X, Xue SG, Ge L, Liu Z, Huang Y, Nie T, Li P, Wu D, Pei D, Zhang Y, Lu L, Yang F, Kimber SJ, Reik W, Zou X, Shang Z, Lai L, Surani A, Tam PPL, Ahmed A, Yeung WSB, Teichmann SA, Niemann H, Liu P.

Nat Cell Biol. 2019 Jun;21(6):687-699. doi: 10.1038/s41556-019-0333-2. Epub 2019 Jun 3.


Exome chip association study excluded the involvement of rare coding variants with large effect sizes in the etiology of anorectal malformations.

van de Putte R, Wijers CHW, Reutter H, Vermeulen SH, Marcelis CLM, Brosens E, Broens PMA, Homberg M, Ludwig M, Jenetzky E, Zwink N, Sloots CEJ, de Klein A, Brooks AS, Hofstra RMW, Holsink SAC, van der Zanden LFM, Galesloot TE, Tam PK, Steehouwer M, Acuna-Hidalgo R, Vorst MV, Kiemeney LA, Garcia-Barceló MM, de Blaauw I, Brunner HG, Roeleveld N, van Rooij IALM.

PLoS One. 2019 May 28;14(5):e0217477. doi: 10.1371/journal.pone.0217477. eCollection 2019.


Residual Renal Function and Effect of Low-Sodium Solution on Blood Pressure in Peritoneal Dialysis Patients.

Rutkowski B, Tam P, van der Sande FM, Vychytil A, Schwenger V, Klein G, Himmele R, Gauly A; Low Sodium balance Study Group.

Perit Dial Int. 2019 Jul-Aug;39(4):335-343. doi: 10.3747/pdi.2018.00120. Epub 2019 May 23.


Mechanistic insights from the LHX1-driven molecular network in building the embryonic head.

McMahon R, Sibbritt T, Salehin N, Osteil P, Tam PPL.

Dev Growth Differ. 2019 Jun;61(5):327-336. doi: 10.1111/dgd.12609. Epub 2019 May 21. Review.


Mutant RAMP2 causes primary open-angle glaucoma via the CRLR-cAMP axis.

Gong B, Zhang H, Huang L, Chen Y, Shi Y, Tam PO, Zhu X, Huang Y, Lei B, Sundaresan P, Li X, Jiang L, Yang J, Lin Y, Lu F, Chen L, Li Y, Leung CK, Guo X, Zhang S, Huang G, Wu Y, Zhou T, Shuai P, Tham CC, Weisschuh N, Krishnadas SR, Mardin C, Reis A, Yang J, Zhang L, Zhou Y, Wang Z, Qu C, Shaw PX, Pang CP, Sun X, Zhu W, Li DY, Pasutto F, Yang Z.

Genet Med. 2019 Oct;21(10):2345-2354. doi: 10.1038/s41436-019-0507-0. Epub 2019 Apr 19.


Chemical Bonding to Novel Translucent Zirconias: A Mechanical and Molecular Investigation.

Franco-Tabares S, Stenport VF, Hjalmarsson L, Tam PL, Johansson CB.

J Adhes Dent. 2019;21(2):107-116. doi: 10.3290/j.jad.a42361.


Dynamics of Wnt activity on the acquisition of ectoderm potency in epiblast stem cells.

Osteil P, Studdert JB, Goh HN, Wilkie EE, Fan X, Khoo PL, Peng G, Salehin N, Knowles H, Han JJ, Jing N, Fossat N, Tam PPL.

Development. 2019 Apr 5;146(7). pii: dev172858. doi: 10.1242/dev.172858.


Single-Cell RNA-Seq Reveals Cellular Heterogeneity of Pluripotency Transition and X Chromosome Dynamics during Early Mouse Development.

Cheng S, Pei Y, He L, Peng G, Reinius B, Tam PPL, Jing N, Deng Q.

Cell Rep. 2019 Mar 5;26(10):2593-2607.e3. doi: 10.1016/j.celrep.2019.02.031.


Gene Editing of Mouse Embryonic and Epiblast Stem Cells.

Sibbritt T, Osteil P, Fan X, Sun J, Salehin N, Knowles H, Shen J, Tam PPL.

Methods Mol Biol. 2019;1940:77-95. doi: 10.1007/978-1-4939-9086-3_6.


Cancer gene mutations in congenital pulmonary airway malformation patients.

Hsu JS, Zhang R, Yeung F, Tang CSM, Wong JKL, So MT, Xia H, Sham P, Tam PK, Li M, Wong KKY, Garcia-Barcelo MM.

ERJ Open Res. 2019 Feb 4;5(1). pii: 00196-2018. doi: 10.1183/23120541.00196-2018. eCollection 2019 Feb.


Consensus statements on the management of clinically localized prostate cancer from the Hong Kong Urological Association and the Hong Kong Society of Uro-Oncology.

Ma WK, Poon DM, Chan CK, Chan TW, Cheung FY, Ho LY, Lee EK, Leung AK, Leung SY, So HS, Tam PC, Kwong PW.

BJU Int. 2019 Aug;124(2):221-241. doi: 10.1111/bju.14681. Epub 2019 Feb 5. Review.


A label-free and highly sensitive DNA biosensor based on the core-shell structured CeO2-NR@Ppy nanocomposite for Salmonella detection.

Nguyet NT, Yen LTH, Doan VY, Hoang NL, Van Thu V, Lan H, Trung T, Pham VH, Tam PD.

Mater Sci Eng C Mater Biol Appl. 2019 Mar;96:790-797. doi: 10.1016/j.msec.2018.11.059. Epub 2018 Nov 28.


Genome-wide analysis identified 17 new loci influencing intraocular pressure in Chinese population.

Huang L, Chen Y, Lin Y, Tam POS, Cheng Y, Shi Y, Gong B, Lu F, Yang J, Wang H, Yin Y, Cao Y, Jiang D, Zhong L, Xue B, Wang J, Hao F, Lee DY, Pang CP, Sun X, Yang Z.

Sci China Life Sci. 2019 Feb;62(2):153-164. doi: 10.1007/s11427-018-9430-2. Epub 2018 Dec 24.


Association of the SIX6 locus with primary open angle glaucoma in southern Chinese and Japanese.

Rong SS, Lu SY, Matsushita K, Huang C, Leung CKS, Kawashima R, Usui S, Tam POS, Young AL, Tsujikawa M, Zhang M, Nishida K, Wiggs JL, Tham CC, Pang CP, Chen LJ.

Exp Eye Res. 2019 Mar;180:129-136. doi: 10.1016/j.exer.2018.12.014. Epub 2018 Dec 23.


Development of pediatric minimally invasive surgery in mainland China.

Diao M, Cheng W, Tam PKH, Li L.

J Pediatr Surg. 2019 Feb;54(2):229-233. doi: 10.1016/j.jpedsurg.2018.10.077. Epub 2018 Nov 6.


Recent trends in the prevalence of Helicobacter Pylori in symptomatic children: A 12-year retrospective study in a tertiary centre.

Tang MYL, Chung PHY, Chan HY, Tam PKH, Wong KK.

J Pediatr Surg. 2019 Feb;54(2):255-257. doi: 10.1016/j.jpedsurg.2018.10.079. Epub 2018 Nov 6.


Clinical characteristics and outcomes of human rhinovirus positivity in hospitalized children.

Tam PI, Zhang L, Cohen Z.

Ann Thorac Med. 2018 Oct-Dec;13(4):230-236. doi: 10.4103/atm.ATM_291_17.


Risk factors for the development of post-operative enterocolitis in short segment Hirschsprung's disease.

Chung PHY, Yu MON, Wong KKY, Tam PKH.

Pediatr Surg Int. 2019 Feb;35(2):187-191. doi: 10.1007/s00383-018-4393-3. Epub 2018 Nov 1.


Mouse gastrulation: Attributes of transcription factor regulatory network for epiblast patterning.

Cui G, Suo S, Wang R, Qian Y, Han JJ, Peng G, Tam PPL, Jing N.

Dev Growth Differ. 2018 Oct;60(8):463-472. doi: 10.1111/dgd.12568.


Updated Canadian Expert Consensus on Assessing Risk of Disease Progression and Pharmacological Management of Autosomal Dominant Polycystic Kidney Disease.

Soroka S, Alam A, Bevilacqua M, Girard LP, Komenda P, Loertscher R, McFarlane P, Pandeya S, Tam P, Bichet DG.

Can J Kidney Health Dis. 2018 Oct 12;5:2054358118801589. doi: 10.1177/2054358118801589. eCollection 2018.


Conditional deletion of platelet derived growth factor receptor alpha (Pdgfra) in urorectal mesenchyme causes mesenchyme apoptosis and urorectal developmental anomalies in mice.

Qian C, Wu Z, Ng RC, Garcia-Barceló MM, Yuan ZW, Wong KKY, Tam PKH, Lui VCH.

Cell Death Differ. 2019 Aug;26(8):1396-1410. doi: 10.1038/s41418-018-0216-2. Epub 2018 Oct 15.


Corrigendum to "Cholangiopathies - Towards a molecular understanding" [EBioMedicine 35 (2018) 381-393].

Tam PKH, Yiu RS, Lendahl U, Andersson ER.

EBioMedicine. 2018 Oct;36:564. doi: 10.1016/j.ebiom.2018.09.044. Epub 2018 Oct 9. No abstract available.


Single-Cell Transcriptomic Analysis of Cardiac Differentiation from Human PSCs Reveals HOPX-Dependent Cardiomyocyte Maturation.

Friedman CE, Nguyen Q, Lukowski SW, Helfer A, Chiu HS, Miklas J, Levy S, Suo S, Han JJ, Osteil P, Peng G, Jing N, Baillie GJ, Senabouth A, Christ AN, Bruxner TJ, Murry CE, Wong ES, Ding J, Wang Y, Hudson J, Ruohola-Baker H, Bar-Joseph Z, Tam PPL, Powell JE, Palpant NJ.

Cell Stem Cell. 2018 Oct 4;23(4):586-598.e8. doi: 10.1016/j.stem.2018.09.009.


Does the identity of the bacteria matter in post-Kasai cholangitis? A comparison between simple and intractable cholangitis.

Chung PHY, Tam PKH, Wong KKY.

J Pediatr Surg. 2018 Dec;53(12):2409-2411. doi: 10.1016/j.jpedsurg.2018.08.028. Epub 2018 Sep 2.


Cholangiopathies - Towards a molecular understanding.

Tam PKH, Yiu RS, Lendahl U, Andersson ER.

EBioMedicine. 2018 Sep;35:381-393. doi: 10.1016/j.ebiom.2018.08.024. Epub 2018 Sep 17. Review. Erratum in: EBioMedicine. 2018 Oct;36:564.


Identification of Genes Associated With Hirschsprung Disease, Based on Whole-Genome Sequence Analysis, and Potential Effects on Enteric Nervous System Development.

Tang CS, Li P, Lai FP, Fu AX, Lau ST, So MT, Lui KN, Li Z, Zhuang X, Yu M, Liu X, Ngo ND, Miao X, Zhang X, Yi B, Tang S, Sun X, Zhang F, Liu H, Liu Q, Zhang R, Wang H, Huang L, Dong X, Tou J, Cheah KS, Yang W, Yuan Z, Yip KY, Sham PC, Tam PK, Garcia-Barcelo MM, Ngan ES.

Gastroenterology. 2018 Dec;155(6):1908-1922.e5. doi: 10.1053/j.gastro.2018.09.012. Epub 2018 Sep 12.


The Role of Neonatal Gr-1+ Myeloid Cells in a Murine Model of Rhesus-Rotavirus-Induced Biliary Atresia.

Zhang R, Lin Z, Fu M, Guan X, Yu J, Zhong W, Zeng J, Lui VCH, Tam PKH, Lamb JR, Xia H, Chen Y.

Am J Pathol. 2018 Nov;188(11):2617-2628. doi: 10.1016/j.ajpath.2018.07.024. Epub 2018 Sep 8.


Internet use by older adults with bipolar disorder: international survey results.

Bauer R, Glenn T, Strejilevich S, Conell J, Alda M, Ardau R, Baune BT, Berk M, Bersudsky Y, Bilderbeck A, Bocchetta A, Castro AMP, Cheung EYW, Chillotti C, Choppin S, Cuomo A, Del Zompo M, Dias R, Dodd S, Duffy A, Etain B, Fagiolini A, Fernández Hernandez M, Garnham J, Geddes J, Gildebro J, Gitlin MJ, Gonzalez-Pinto A, Goodwin GM, Grof P, Harima H, Hassel S, Henry C, Hidalgo-Mazzei D, Lund AH, Kapur V, Kunigiri G, Lafer B, Larsen ER, Lewitzka U, Licht RW, Misiak B, Piotrowski P, Miranda-Scippa Â, Monteith S, Munoz R, Nakanotani T, Nielsen RE, O'Donovan C, Okamura Y, Osher Y, Reif A, Ritter P, Rybakowski JK, Sagduyu K, Sawchuk B, Schwartz E, Slaney C, Sulaiman AH, Suominen K, Suwalska A, Tam P, Tatebayashi Y, Tondo L, Veeh J, Vieta E, Vinberg M, Viswanath B, Zetin M, Whybrow PC, Bauer M.

Int J Bipolar Disord. 2018 Sep 4;6(1):20. doi: 10.1186/s40345-018-0127-7.


Congenital pulmonary airway malformation: advances and controversies.

Wong KKY, Flake AW, Tibboel D, Rottier RJ, Tam PKH.

Lancet Child Adolesc Health. 2018 Apr;2(4):290-297. doi: 10.1016/S2352-4642(18)30035-X. Epub 2018 Feb 17. Review.


A gene regulatory network anchored by LIM homeobox 1 for embryonic head development.

Sibbritt T, Ip CK, Khoo PL, Wilkie E, Jones V, Sun JQJ, Shen JX, Peng G, Han JJ, Jing N, Osteil P, Ramialison M, Tam PPL, Fossat N.

Genesis. 2018 Sep;56(9):e23246. doi: 10.1002/dvg.23246. Epub 2018 Sep 14.


Downregulation of Hes1 expression in experimental biliary atresia and its effects on bile duct structure.

Zhang RZ, Zeng XH, Lin ZF, Ming-Fu, Tong YL, Lui VC, Tam PK, Lamb JR, Xia HM, Chen Y.

World J Gastroenterol. 2018 Aug 7;24(29):3260-3272. doi: 10.3748/wjg.v24.i29.3260.

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