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Items: 48

1.

Kras/ADAM17-dependent Jag1-ICD reverse signalling sustains colorectal cancer progression and chemoresistance.

Pelullo M, Nardozza F, Zema S, Quaranta R, Nicoletti C, Besharat ZM, Felli MP, Cerbelli B, d'Amati G, Palermo R, Capalbo C, Talora C, Di Marcotullio L, Giannini G, Checquolo S, Screpanti I, Bellavia D.

Cancer Res. 2019 Sep 10. pii: canres.0145.2019. doi: 10.1158/0008-5472.CAN-19-0145. [Epub ahead of print]

PMID:
31506332
2.
3.

Histone Modifications Drive Aberrant Notch3 Expression/Activity and Growth in T-ALL.

Tottone L, Zhdanovskaya N, Carmona Pestaña Á, Zampieri M, Simeoni F, Lazzari S, Ruocco V, Pelullo M, Caiafa P, Felli MP, Checquolo S, Bellavia D, Talora C, Screpanti I, Palermo R.

Front Oncol. 2019 Apr 3;9:198. doi: 10.3389/fonc.2019.00198. eCollection 2019.

4.

DNA Damage Stress: Cui Prodest?

Verma N, Franchitto M, Zonfrilli A, Cialfi S, Palermo R, Talora C.

Int J Mol Sci. 2019 Mar 1;20(5). pii: E1073. doi: 10.3390/ijms20051073. Review.

5.

Autophagy processes are dependent on EGF receptor signaling.

De Iuliis V, Marino A, Caruso M, Capodifoglio S, Flati V, Marynuk A, Marricareda V, Ursi S, Lanuti P, Talora C, Conti P, Martinotti S, Toniato E.

Oncotarget. 2018 Jul 13;9(54):30289-30303. doi: 10.18632/oncotarget.25708. eCollection 2018 Jul 13.

6.

Yeast-Based Screen to Identify Natural Compounds with a Potential Therapeutic Effect in Hailey-Hailey Disease.

Ficociello G, Zonfrilli A, Cialfi S, Talora C, Uccelletti D.

Int J Mol Sci. 2018 Jun 20;19(6). pii: E1814. doi: 10.3390/ijms19061814.

7.

Mir-34a-5p Mediates Cross-Talk between M2 Muscarinic Receptors and Notch-1/EGFR Pathways in U87MG Glioblastoma Cells: Implication in Cell Proliferation.

Di Bari M, Bevilacqua V, De Jaco A, Laneve P, Piovesana R, Trobiani L, Talora C, Caffarelli E, Tata AM.

Int J Mol Sci. 2018 May 31;19(6). pii: E1631. doi: 10.3390/ijms19061631.

8.

NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest.

Diluvio G, Del Gaudio F, Giuli MV, Franciosa G, Giuliani E, Palermo R, Besharat ZM, Pignataro MG, Vacca A, d'Amati G, Maroder M, Talora C, Capalbo C, Bellavia D, Checquolo S.

Oncogenesis. 2018 May 25;7(5):42. doi: 10.1038/s41389-018-0051-9.

9.

Maml1 acts cooperatively with Gli proteins to regulate sonic hedgehog signaling pathway.

Quaranta R, Pelullo M, Zema S, Nardozza F, Checquolo S, Lauer DM, Bufalieri F, Palermo R, Felli MP, Vacca A, Talora C, Di Marcotullio L, Screpanti I, Bellavia D.

Cell Death Dis. 2017 Jul 20;8(7):e2942. doi: 10.1038/cddis.2017.326.

10.

Identification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemia.

Mori M, Tottone L, Quaglio D, Zhdanovskaya N, Ingallina C, Fusto M, Ghirga F, Peruzzi G, Crestoni ME, Simeoni F, Giulimondi F, Talora C, Botta B, Screpanti I, Palermo R.

Sci Rep. 2017 May 19;7(1):2213. doi: 10.1038/s41598-017-02316-9.

11.

Corrigendum: The loss of ATP2C1 impairs the DNA damage response and induces altered skin homeostasis: Consequences for epidermal biology in Hailey-Hailey disease.

Cialfi S, Le Pera L, De Blasio C, Mariano G, Palermo R, Zonfrilli A, Uccelletti D, Palleschi C, Biolcati G, Barbieri L, Screpanti I, Talora C.

Sci Rep. 2017 Mar 16;7:44514. doi: 10.1038/srep44514. No abstract available.

12.

The loss of ATP2C1 impairs the DNA damage response and induces altered skin homeostasis: Consequences for epidermal biology in Hailey-Hailey disease.

Cialfi S, Le Pera L, De Blasio C, Mariano G, Palermo R, Zonfrilli A, Uccelletti D, Palleschi C, Biolcati G, Barbieri L, Screpanti I, Talora C.

Sci Rep. 2016 Aug 16;6:31567. doi: 10.1038/srep31567. Erratum in: Sci Rep. 2017 Mar 16;7:44514.

13.

Glutathione S-transferase ϴ-subunit as a phenotypic suppressor of pmr1Δ strain, the Kluyveromyces lactis model for Hailey-Hailey disease.

Ficociello G, Zanni E, Cialfi S, Aurizi C, Biolcati G, Palleschi C, Talora C, Uccelletti D.

Biochim Biophys Acta. 2016 Nov;1863(11):2650-2657. doi: 10.1016/j.bbamcr.2016.08.002. Epub 2016 Aug 11.

14.

A threshold level of NFATc1 activity facilitates thymocyte differentiation and opposes notch-driven leukaemia development.

Klein-Hessling S, Rudolf R, Muhammad K, Knobeloch KP, Maqbool MA, Cauchy P, Andrau JC, Avots A, Talora C, Ellenrieder V, Screpanti I, Serfling E, Patra AK.

Nat Commun. 2016 Jun 17;7:11841. doi: 10.1038/ncomms11841.

15.

Regulation of proapoptotic proteins Bak1 and p53 by miR-125b in an experimental model of Alzheimer's disease: Protective role of 17β-estradiol.

Micheli F, Palermo R, Talora C, Ferretti E, Vacca A, Napolitano M.

Neurosci Lett. 2016 Aug 26;629:234-240. doi: 10.1016/j.neulet.2016.05.049. Epub 2016 May 25.

PMID:
27235580
16.

Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression.

Franciosa G, Diluvio G, Gaudio FD, Giuli MV, Palermo R, Grazioli P, Campese AF, Talora C, Bellavia D, D'Amati G, Besharat ZM, Nicoletti C, Siebel CW, Choy L, Rustighi A, Sal GD, Screpanti I, Checquolo S.

Oncogene. 2016 Sep 8;35(36):4741-51. doi: 10.1038/onc.2016.5. Epub 2016 Feb 15.

17.

The deregulated expression of miR-125b in acute myeloid leukemia is dependent on the transcription factor C/EBPα.

Vargas Romero P, Cialfi S, Palermo R, De Blasio C, Checquolo S, Bellavia D, Chiaretti S, Foà R, Amadori A, Gulino A, Zardo G, Talora C, Screpanti I.

Leukemia. 2015 Dec;29(12):2442-5. doi: 10.1038/leu.2015.117. Epub 2015 May 18. No abstract available.

18.

Notch3/Jagged1 circuitry reinforces notch signaling and sustains T-ALL.

Pelullo M, Quaranta R, Talora C, Checquolo S, Cialfi S, Felli MP, te Kronnie G, Borga C, Besharat ZM, Palermo R, Di Marcotullio L, Capobianco AJ, Gulino A, Screpanti I, Bellavia D.

Neoplasia. 2014 Dec;16(12):1007-17. doi: 10.1016/j.neo.2014.10.004.

19.

The epigenetic factor BORIS/CTCFL regulates the NOTCH3 gene expression in cancer cells.

Zampieri M, Ciccarone F, Palermo R, Cialfi S, Passananti C, Chiaretti S, Nocchia D, Talora C, Screpanti I, Caiafa P.

Biochim Biophys Acta. 2014 Sep;1839(9):813-25. doi: 10.1016/j.bbagrm.2014.06.017. Epub 2014 Jun 28.

20.

Loss of Notch1-dependent p21(Waf1/Cip1) expression influences the Notch1 outcome in tumorigenesis.

Cialfi S, Palermo R, Manca S, De Blasio C, Vargas Romero P, Checquolo S, Bellavia D, Uccelletti D, Saliola M, D'Alessandro A, Zolla L, Gulino A, Screpanti I, Talora C.

Cell Cycle. 2014;13(13):2046-55. doi: 10.4161/cc.29079. Epub 2014 May 6.

21.

Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia.

Kumar V, Palermo R, Talora C, Campese AF, Checquolo S, Bellavia D, Tottone L, Testa G, Miele E, Indraccolo S, Amadori A, Ferretti E, Gulino A, Vacca A, Screpanti I.

Leukemia. 2014 Dec;28(12):2324-35. doi: 10.1038/leu.2014.133. Epub 2014 Apr 14.

PMID:
24727676
22.

M2 muscarinic receptor activation regulates Schwann cell differentiation and myelin organization.

Uggenti C, De Stefano ME, Costantino M, Loreti S, Pisano A, Avallone B, Talora C, Magnaghi V, Tata AM.

Dev Neurobiol. 2014 Jul;74(7):676-91. doi: 10.1002/dneu.22161. Epub 2014 Jan 9.

23.

Efficacy of the melanocortin analogue Nle4-D-Phe7-α-melanocyte-stimulating hormone in the treatment of patients with Hailey-Hailey disease.

Biolcati G, Aurizi C, Barbieri L, Cialfi S, Screpanti I, Talora C.

Clin Exp Dermatol. 2014 Mar;39(2):168-75. doi: 10.1111/ced.12203. Epub 2013 Oct 25.

24.

The molecular basis of notch signaling regulation: a complex simplicity.

Palermo R, Checquolo S, Bellavia D, Talora C, Screpanti I.

Curr Mol Med. 2014 Jan;14(1):34-44. Review.

PMID:
24236458
25.

Inhibition of microbial growth by carbon nanotube networks.

Olivi M, Zanni E, De Bellis G, Talora C, Sarto MS, Palleschi C, Flahaut E, Monthioux M, Rapino S, Uccelletti D, Fiorito S.

Nanoscale. 2013 Oct 7;5(19):9023-9. doi: 10.1039/c3nr02091f. Epub 2013 Aug 9.

PMID:
23934344
26.

Glucocorticoid sensitivity of T-cell lymphoblastic leukemia/lymphoma is associated with glucocorticoid receptor-mediated inhibition of Notch1 expression.

Cialfi S, Palermo R, Manca S, Checquolo S, Bellavia D, Pelullo M, Quaranta R, Dominici C, Gulino A, Screpanti I, Talora C.

Leukemia. 2013 Feb;27(2):485-8. doi: 10.1038/leu.2012.192. Epub 2012 Jul 13. No abstract available.

PMID:
22846929
27.

The translation factor eIF6 is a Notch-dependent regulator of cell migration and invasion.

Benelli D, Cialfi S, Pinzaglia M, Talora C, Londei P.

PLoS One. 2012;7(2):e32047. doi: 10.1371/journal.pone.0032047. Epub 2012 Feb 14.

28.

Oxidative stress activation of miR-125b is part of the molecular switch for Hailey-Hailey disease manifestation.

Manca S, Magrelli A, Cialfi S, Lefort K, Ambra R, Alimandi M, Biolcati G, Uccelletti D, Palleschi C, Screpanti I, Candi E, Melino G, Salvatore M, Taruscio D, Talora C.

Exp Dermatol. 2011 Nov;20(11):932-7. doi: 10.1111/j.1600-0625.2011.01359.x. Epub 2011 Sep 14.

PMID:
21913998
29.

Differential subcellular localization regulates c-Cbl E3 ligase activity upon Notch3 protein in T-cell leukemia.

Checquolo S, Palermo R, Cialfi S, Ferrara G, Oliviero C, Talora C, Bellavia D, Giovenco A, Grazioli P, Frati L, Gulino A, Screpanti I.

Oncogene. 2010 Mar 11;29(10):1463-74. doi: 10.1038/onc.2009.446. Epub 2009 Dec 7.

PMID:
19966856
30.

Complex multipathways alterations and oxidative stress are associated with Hailey-Hailey disease.

Cialfi S, Oliviero C, Ceccarelli S, Marchese C, Barbieri L, Biolcati G, Uccelletti D, Palleschi C, Barboni L, De Bernardo C, Grammatico P, Magrelli A, Salvatore M, Taruscio D, Frati L, Gulino A, Screpanti I, Talora C.

Br J Dermatol. 2010 Mar;162(3):518-26. doi: 10.1111/j.1365-2133.2009.09500.x. Epub 2009 Nov 9.

PMID:
19903178
31.

SOD1, a new Kluyveromyces lactis helper gene for heterologous protein secretion.

Raimondi S, Zanni E, Talora C, Rossi M, Palleschi C, Uccelletti D.

Appl Environ Microbiol. 2008 Dec;74(23):7130-7. doi: 10.1128/AEM.00955-08. Epub 2008 Oct 3.

32.

Human papilloma virus-dependent HMGA1 expression is a relevant step in cervical carcinogenesis.

Mellone M, Rinaldi C, Massimi I, Petroni M, Veschi V, Talora C, Truffa S, Stabile H, Frati L, Screpanti I, Gulino A, Giannini G.

Neoplasia. 2008 Aug;10(8):773-81.

33.

Notch signaling and diseases: an evolutionary journey from a simple beginning to complex outcomes.

Talora C, Campese AF, Bellavia D, Felli MP, Vacca A, Gulino A, Screpanti I.

Biochim Biophys Acta. 2008 Sep;1782(9):489-97. doi: 10.1016/j.bbadis.2008.06.008. Epub 2008 Jun 24. Review.

34.

Notch3 and the Notch3-upregulated RNA-binding protein HuD regulate Ikaros alternative splicing.

Bellavia D, Mecarozzi M, Campese AF, Grazioli P, Talora C, Frati L, Gulino A, Screpanti I.

EMBO J. 2007 Mar 21;26(6):1670-80. Epub 2007 Mar 1.

35.

Cross talk among Notch3, pre-TCR, and Tal1 in T-cell development and leukemogenesis.

Talora C, Cialfi S, Oliviero C, Palermo R, Pascucci M, Frati L, Vacca A, Gulino A, Screpanti I.

Blood. 2006 Apr 15;107(8):3313-20. Epub 2005 Dec 20.

36.

The Golgi Ca2+-ATPase KlPmr1p function is required for oxidative stress response by controlling the expression of the heat-shock element HSP60 in Kluyveromyces lactis.

Uccelletti D, Farina F, Pinton P, Goffrini P, Mancini P, Talora C, Rizzuto R, Palleschi C.

Mol Biol Cell. 2005 Oct;16(10):4636-47. Epub 2005 Jul 19.

37.

Constitutively active Notch1 induces growth arrest of HPV-positive cervical cancer cells via separate signaling pathways.

Talora C, Cialfi S, Segatto O, Morrone S, Kim Choi J, Frati L, Paolo Dotto G, Gulino A, Screpanti I.

Exp Cell Res. 2005 May 1;305(2):343-54.

PMID:
15817159
38.

PKC theta mediates pre-TCR signaling and contributes to Notch3-induced T-cell leukemia.

Felli MP, Vacca A, Calce A, Bellavia D, Campese AF, Grillo R, Di Giovine M, Checquolo S, Talora C, Palermo R, Di Mario G, Frati L, Gulino A, Screpanti I.

Oncogene. 2005 Feb 3;24(6):992-1000.

PMID:
15592506
39.

High commitment of embryonic keratinocytes to terminal differentiation through a Notch1-caspase 3 regulatory mechanism.

Okuyama R, Nguyen BC, Talora C, Ogawa E, Tommasi di Vignano A, Lioumi M, Chiorino G, Tagami H, Woo M, Dotto GP.

Dev Cell. 2004 Apr;6(4):551-62.

40.

Pre-TCR-triggered ERK signalling-dependent downregulation of E2A activity in Notch3-induced T-cell lymphoma.

Talora C, Campese AF, Bellavia D, Pascucci M, Checquolo S, Groppioni M, Frati L, von Boehmer H, Gulino A, Screpanti I.

EMBO Rep. 2003 Nov;4(11):1067-72. Epub 2003 Oct 17.

42.

Cross talk among calcineurin, Sp1/Sp3, and NFAT in control of p21(WAF1/CIP1) expression in keratinocyte differentiation.

Santini MP, Talora C, Seki T, Bolgan L, Dotto GP.

Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9575-80. Epub 2001 Aug 7.

43.

Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation.

Rangarajan A, Talora C, Okuyama R, Nicolas M, Mammucari C, Oh H, Aster JC, Krishna S, Metzger D, Chambon P, Miele L, Aguet M, Radtke F, Dotto GP.

EMBO J. 2001 Jul 2;20(13):3427-36.

44.

A PKC-eta/Fyn-dependent pathway leading to keratinocyte growth arrest and differentiation.

Cabodi S, Calautti E, Talora C, Kuroki T, Stein PL, Dotto GP.

Mol Cell. 2000 Nov;6(5):1121-9.

45.

Inhibition of ErbB-2 mitogenic and transforming activity by RALT, a mitogen-induced signal transducer which binds to the ErbB-2 kinase domain.

Fiorentino L, Pertica C, Fiorini M, Talora C, Crescenzi M, Castellani L, Alemà S, Benedetti P, Segatto O.

Mol Cell Biol. 2000 Oct;20(20):7735-50.

46.

Role of a white collar-1-white collar-2 complex in blue-light signal transduction.

Talora C, Franchi L, Linden H, Ballario P, Macino G.

EMBO J. 1999 Sep 15;18(18):4961-8.

47.

Roles in dimerization and blue light photoresponse of the PAS and LOV domains of Neurospora crassa white collar proteins.

Ballario P, Talora C, Galli D, Linden H, Macino G.

Mol Microbiol. 1998 Aug;29(3):719-29.

48.

White collar-1, a central regulator of blue light responses in Neurospora, is a zinc finger protein.

Ballario P, Vittorioso P, Magrelli A, Talora C, Cabibbo A, Macino G.

EMBO J. 1996 Apr 1;15(7):1650-7.

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