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Speaking up about care concerns in the ICU: patient and family experiences, attitudes and perceived barriers.

Bell SK, Roche SD, Mueller A, Dente E, O'Reilly K, Sarnoff Lee B, Sands K, Talmor D, Brown SM.

BMJ Qual Saf. 2018 Jul 12. pii: bmjqs-2017-007525. doi: 10.1136/bmjqs-2017-007525. [Epub ahead of print]


Building communities of respect in the intensive care unit.

Brown SM, Talmor D, Howell MD.

Intensive Care Med. 2018 Jun 30. doi: 10.1007/s00134-018-5259-9. [Epub ahead of print] No abstract available.


Shock subtypes by left ventricular ejection fraction following out-of-hospital cardiac arrest.

Anderson RJ, Jinadasa SP, Hsu L, Ghafouri TB, Tyagi S, Joshua J, Mueller A, Talmor D, Sell RE, Beitler JR.

Crit Care. 2018 Jun 15;22(1):162. doi: 10.1186/s13054-018-2078-x.


Outcome in patients perceived as receiving excessive care across different ethical climates: a prospective study in 68 intensive care units in Europe and the USA.

Benoit DD, Jensen HI, Malmgren J, Metaxa V, Reyners AK, Darmon M, Rusinova K, Talmor D, Meert AP, Cancelliere L, Zubek L, Maia P, Michalsen A, Vanheule S, Kompanje EJO, Decruyenaere J, Vandenberghe S, Vansteelandt S, Gadeyne B, Van den Bulcke B, Azoulay E, Piers RD; DISPROPRICUS study group of the Ethics Section of the European Society of Intensive Care Medicine.

Intensive Care Med. 2018 Jul;44(7):1039-1049. doi: 10.1007/s00134-018-5231-8. Epub 2018 May 28.


Early Intravascular Events Are Associated with Development of Acute Respiratory Distress Syndrome. A Substudy of the LIPS-A Clinical Trial.

Abdulnour RE, Gunderson T, Barkas I, Timmons JY, Barnig C, Gong M, Kor DJ, Gajic O, Talmor D, Carter RE, Levy BD.

Am J Respir Crit Care Med. 2018 Jun 15;197(12):1575-1585. doi: 10.1164/rccm.201712-2530OC.


Liberal Versus Restrictive Intravenous Fluid Therapy for Early Septic Shock: Rationale for a Randomized Trial.

Self WH, Semler MW, Bellomo R, Brown SM, deBoisblanc BP, Exline MC, Ginde AA, Grissom CK, Janz DR, Jones AE, Liu KD, Macdonald SPJ, Miller CD, Park PK, Reineck LA, Rice TW, Steingrub JS, Talmor D, Yealy DM, Douglas IS, Shapiro NI; CLOVERS Protocol Committee and NHLBI Prevention and Early Treatment of Acute Lung Injury (PETAL) Network Investigators.

Ann Emerg Med. 2018 May 9. pii: S0196-0644(18)30315-9. doi: 10.1016/j.annemergmed.2018.03.039. [Epub ahead of print]


Cost-Effectiveness Research in Anesthesiology.

Teja BJ, Sutherland TN, Barnett SR, Talmor DS.

Anesth Analg. 2018 Mar 21. doi: 10.1213/ANE.0000000000003334. [Epub ahead of print]


Update in Critical Care Medicine 2017.

Thille AW, Mauri T, Talmor D.

Am J Respir Crit Care Med. 2018 Jun 1;197(11):1382-1388. doi: 10.1164/rccm.201801-0055UP. No abstract available.


Effects of Prone Positioning on Transpulmonary Pressures and End-expiratory Volumes in Patients without Lung Disease.

Kumaresan A, Gerber R, Mueller A, Loring SH, Talmor D.

Anesthesiology. 2018 Jun;128(6):1187-1192. doi: 10.1097/ALN.0000000000002159.


Lung volumes and transpulmonary pressure are decreased with expiratory effort and restored with passive breathing in ARDS: a reapplication of the traditional Campbell diagram.

Baedorf Kassis E, Loring SH, Talmor D.

Intensive Care Med. 2018 Apr;44(4):534-536. doi: 10.1007/s00134-018-5105-0. Epub 2018 Mar 7. No abstract available.


Ethical decision-making climate in the ICU: theoretical framework and validation of a self-assessment tool.

Van den Bulcke B, Piers R, Jensen HI, Malmgren J, Metaxa V, Reyners AK, Darmon M, Rusinova K, Talmor D, Meert AP, Cancelliere L, Zubek L, Maia P, Michalsen A, Decruyenaere J, Kompanje EJO, Azoulay E, Meganck R, Van de Sompel A, Vansteelandt S, Vlerick P, Vanheule S, Benoit DD.

BMJ Qual Saf. 2018 Feb 23. pii: bmjqs-2017-007390. doi: 10.1136/bmjqs-2017-007390. [Epub ahead of print]


Interaction between peri-operative blood transfusion, tidal volume, airway pressure and postoperative ARDS: an individual patient data meta-analysis.

Serpa Neto A, Juffermans NP, Hemmes SNT, Barbas CSV, Beiderlinden M, Biehl M, Fernandez-Bustamante A, Futier E, Gajic O, Jaber S, Kozian A, Licker M, Lin WQ, Memtsoudis SG, Miranda DR, Moine P, Paparella D, Ranieri M, Scavonetto F, Schilling T, Selmo G, Severgnini P, Sprung J, Sundar S, Talmor D, Treschan T, Unzueta C, Weingarten TN, Wolthuis EK, Wrigge H, de Abreu MG, Pelosi P, Schultz MJ; PROVE Network Investigators.

Ann Transl Med. 2018 Jan;6(2):23. doi: 10.21037/atm.2018.01.16.


The Practice of Respect in the ICU.

Brown SM, Azoulay E, Benoit D, Butler TP, Folcarelli P, Geller G, Rozenblum R, Sands K, Sokol-Hessner L, Talmor D, Turner K, Howell MD.

Am J Respir Crit Care Med. 2018 Jun 1;197(11):1389-1395. doi: 10.1164/rccm.201708-1676CP.


Intraoperative oxygen concentration and neurocognition after cardiac surgery: study protocol for a randomized controlled trial.

Shaefi S, Marcantonio ER, Mueller A, Banner-Goodspeed V, Robson SC, Spear K, Otterbein LE, O'Gara BP, Talmor DS, Subramaniam B.

Trials. 2017 Dec 19;18(1):600. doi: 10.1186/s13063-017-2337-1.


Esophageal pressure: research or clinical tool?

Baedorf Kassis E, Loring SH, Talmor D.

Med Klin Intensivmed Notfmed. 2018 Feb;113(Suppl 1):13-20. doi: 10.1007/s00063-017-0372-z. Epub 2017 Nov 13. Review.


Higher PEEP versus Lower PEEP Strategies for Patients with Acute Respiratory Distress Syndrome. A Systematic Review and Meta-Analysis.

Walkey AJ, Del Sorbo L, Hodgson CL, Adhikari NKJ, Wunsch H, Meade MO, Uleryk E, Hess D, Talmor DS, Thompson BT, Brower RG, Fan E.

Ann Am Thorac Soc. 2017 Oct;14(Supplement_4):S297-S303. doi: 10.1513/AnnalsATS.201704-338OT. Review.


Respiratory support in patients with acute respiratory distress syndrome: an expert opinion.

Chiumello D, Brochard L, Marini JJ, Slutsky AS, Mancebo J, Ranieri VM, Thompson BT, Papazian L, Schultz MJ, Amato M, Gattinoni L, Mercat A, Pesenti A, Talmor D, Vincent JL.

Crit Care. 2017 Sep 12;21(1):240. doi: 10.1186/s13054-017-1820-0. Review.


Low Tidal Volume versus Non-Volume-Limited Strategies for Patients with Acute Respiratory Distress Syndrome. A Systematic Review and Meta-Analysis.

Walkey AJ, Goligher EC, Del Sorbo L, Hodgson CL, Adhikari NKJ, Wunsch H, Meade MO, Uleryk E, Hess D, Talmor DS, Thompson BT, Brower RG, Fan E.

Ann Am Thorac Soc. 2017 Oct;14(Supplement_4):S271-S279. doi: 10.1513/AnnalsATS.201704-337OT. Review.


How to better identify patients at high risk of postoperative complications?

Talmor D, Kelly B.

Curr Opin Crit Care. 2017 Oct;23(5):417-423. doi: 10.1097/MCC.0000000000000445. Review.


The Effect of ARDS on Survival: Do Patients Die From ARDS or With ARDS?

Fuchs L, Feng M, Novack V, Lee J, Taylor J, Scott D, Howell M, Celi L, Talmor D.

J Intensive Care Med. 2017 Jan 1:885066617717659. doi: 10.1177/0885066617717659. [Epub ahead of print]


A fixed correction of absolute transpulmonary pressure may not be ideal for clinical use : Discussion on "Accuracy of esophageal pressure to assess transpulmonary pressure during mechanical ventilation".

Baedorf Kassis E, Loring SH, Talmor D, Terragni P, Mascia L, Ranieri VM.

Intensive Care Med. 2017 Sep;43(9):1436-1437. doi: 10.1007/s00134-017-4823-z. Epub 2017 May 15. No abstract available.


An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome.

Fan E, Del Sorbo L, Goligher EC, Hodgson CL, Munshi L, Walkey AJ, Adhikari NKJ, Amato MBP, Branson R, Brower RG, Ferguson ND, Gajic O, Gattinoni L, Hess D, Mancebo J, Meade MO, McAuley DF, Pesenti A, Ranieri VM, Rubenfeld GD, Rubin E, Seckel M, Slutsky AS, Talmor D, Thompson BT, Wunsch H, Uleryk E, Brozek J, Brochard LJ; American Thoracic Society, European Society of Intensive Care Medicine, and Society of Critical Care Medicine.

Am J Respir Crit Care Med. 2017 May 1;195(9):1253-1263. doi: 10.1164/rccm.201703-0548ST. Erratum in: Am J Respir Crit Care Med. 2017 Jun 1;195(11):1540.


Ultrasound as a Screening Tool for Central Venous Catheter Positioning and Exclusion of Pneumothorax.

Amir R, Knio ZO, Mahmood F, Oren-Grinberg A, Leibowitz A, Bose R, Shaefi S, Mitchell JD, Ahmed M, Bardia A, Talmor D, Matyal R.

Crit Care Med. 2017 Jul;45(7):1192-1198. doi: 10.1097/CCM.0000000000002451.


Recruitment maneuvers: using transpulmonary pressure to help Goldilocks.

Baedorf Kassis E, Loring SH, Talmor D.

Intensive Care Med. 2017 Aug;43(8):1162-1163. doi: 10.1007/s00134-017-4784-2. Epub 2017 Apr 6. No abstract available.


Current challenges in the management of sepsis in ICUs in resource-poor settings and suggestions for the future.

Schultz MJ, Dunser MW, Dondorp AM, Adhikari NK, Iyer S, Kwizera A, Lubell Y, Papali A, Pisani L, Riviello BD, Angus DC, Azevedo LC, Baker T, Diaz JV, Festic E, Haniffa R, Jawa R, Jacob ST, Kissoon N, Lodha R, Martin-Loeches I, Lundeg G, Misango D, Mer M, Mohanty S, Murthy S, Musa N, Nakibuuka J, Serpa Neto A, Nguyen Thi Hoang M, Nguyen Thien B, Pattnaik R, Phua J, Preller J, Povoa P, Ranjit S, Talmor D, Thevanayagam J, Thwaites CL; Global Intensive Care Working Group of the European Society of Intensive Care Medicine.

Intensive Care Med. 2017 May;43(5):612-624. doi: 10.1007/s00134-017-4750-z. Epub 2017 Mar 27. Review.


Quantifying the Mortality Impact of Do-Not-Resuscitate Orders in the ICU.

Fuchs L, Anstey M, Feng M, Toledano R, Kogan S, Howell MD, Clardy P, Celi L, Talmor D, Novack V.

Crit Care Med. 2017 Jun;45(6):1019-1027. doi: 10.1097/CCM.0000000000002312.


Favorable Neurocognitive Outcome with Low Tidal Volume Ventilation after Cardiac Arrest.

Beitler JR, Ghafouri TB, Jinadasa SP, Mueller A, Hsu L, Anderson RJ, Joshua J, Tyagi S, Malhotra A, Sell RE, Talmor D.

Am J Respir Crit Care Med. 2017 May 1;195(9):1198-1206. doi: 10.1164/rccm.201609-1771OC.


Randomized Clinical Trial of a Combination of an Inhaled Corticosteroid and Beta Agonist in Patients at Risk of Developing the Acute Respiratory Distress Syndrome.

Festic E, Carr GE, Cartin-Ceba R, Hinds RF, Banner-Goodspeed V, Bansal V, Asuni AT, Talmor D, Rajagopalan G, Frank RD, Gajic O, Matthay MA, Levitt JE.

Crit Care Med. 2017 May;45(5):798-805. doi: 10.1097/CCM.0000000000002284.


Video Laryngoscopy in the Intensive Care Unit: Seeing Is Believing, But That Does Not Mean It's True.

O'Gara B, Brown S, Talmor D.

JAMA. 2017 Feb 7;317(5):479-480. doi: 10.1001/jama.2016.21036. No abstract available.


Interval Changes in Myocardial Performance Index Predict Outcome in Severe Sepsis.

Nizamuddin J, Mahmood F, Tung A, Mueller A, Brown SM, Shaefi S, O'Connor M, Talmor D, Shahul S.

J Cardiothorac Vasc Anesth. 2017 Jun;31(3):957-964. doi: 10.1053/j.jvca.2016.11.007. Epub 2016 Nov 2.


The Association Between Preoperative Hemoglobin A1C and Postoperative Glycemic Variability on 30-Day Major Adverse Outcomes Following Isolated Cardiac Valvular Surgery.

Bardia A, Khabbaz K, Mueller A, Mathur P, Novack V, Talmor D, Subramaniam B.

Anesth Analg. 2017 Jan;124(1):16-22.


The Effect of Positive End-Expiratory Pressure on Intracranial Pressure and Cerebral Hemodynamics.

Boone MD, Jinadasa SP, Mueller A, Shaefi S, Kasper EM, Hanafy KA, O'Gara BP, Talmor DS.

Neurocrit Care. 2017 Apr;26(2):174-181. doi: 10.1007/s12028-016-0328-9.


Design and Rationale of the Reevaluation of Systemic Early Neuromuscular Blockade Trial for Acute Respiratory Distress Syndrome.

Huang DT, Angus DC, Moss M, Thompson BT, Ferguson ND, Ginde A, Gong MN, Gundel S, Hayden DL, Hite RD, Hou PC, Hough CL, Iwashyna TJ, Liu KD, Talmor DS, Yealy DM; Reevaluation of Systemic Early Neuromuscular Blockade Protocol Committee and the National Institutes of Health National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury Network Investigators.

Ann Am Thorac Soc. 2017 Jan;14(1):124-133. doi: 10.1513/AnnalsATS.201608-629OT.


Is transpulmonary pressure-guided PEEP titration really optimal? Response to Yamaga et al.

Kassis EB, Loring SH, Talmor D.

Intensive Care Med. 2016 Nov;42(11):1847-1848. Epub 2016 Sep 19. No abstract available.


Early, goal-directed mobilisation in the surgical intensive care unit: a randomised controlled trial.

Schaller SJ, Anstey M, Blobner M, Edrich T, Grabitz SD, Gradwohl-Matis I, Heim M, Houle T, Kurth T, Latronico N, Lee J, Meyer MJ, Peponis T, Talmor D, Velmahos GC, Waak K, Walz JM, Zafonte R, Eikermann M; International Early SOMS-guided Mobilization Research Initiative.

Lancet. 2016 Oct 1;388(10052):1377-1388. doi: 10.1016/S0140-6736(16)31637-3.


Clinician Perspectives on an Electronic Portal to Improve Communication with Patients and Families in the Intensive Care Unit.

Bell SK, Roche SD, Johansson AC, O'Reilly KP, Lee BS, Sands KE, Talmor DS, Brown SM.

Ann Am Thorac Soc. 2016 Dec;13(12):2197-2206.


Oxygen as an Essential Medicine: Under- and Over-Treatment of Hypoxemia in Low- and High-Income Nations.

Sutherland T, Musafiri S, Twagirumugabe T, Talmor D, Riviello ED.

Crit Care Med. 2016 Oct;44(10):e1015-6. doi: 10.1097/CCM.0000000000001912. No abstract available.


Relative Bradycardia in Patients With Septic Shock Requiring Vasopressor Therapy.

Beesley SJ, Wilson EL, Lanspa MJ, Grissom CK, Shahul S, Talmor D, Brown SM.

Crit Care Med. 2017 Feb;45(2):225-233. doi: 10.1097/CCM.0000000000002065.


Effect of high-frequency oscillatory ventilation on esophageal and transpulmonary pressures in moderate-to-severe acute respiratory distress syndrome.

Guervilly C, Forel JM, Hraiech S, Roch A, Talmor D, Papazian L.

Ann Intensive Care. 2016 Dec;6(1):84. doi: 10.1186/s13613-016-0181-1. Epub 2016 Aug 30.


Extremes of shock index predicts death in trauma patients.

Odom SR, Howell MD, Gupta A, Silva G, Cook CH, Talmor D.

J Emerg Trauma Shock. 2016 Jul-Sep;9(3):103-6. doi: 10.4103/0974-2700.185272.


Oxygen Therapy: When Is Too Much Too Much?

Shaefi S, Talmor DS, Subramaniam B.

Anesthesiology. 2016 Sep;125(3):449-50. doi: 10.1097/ALN.0000000000001227. No abstract available.


Lung protective properties of the volatile anesthetics.

O'Gara B, Talmor D.

Intensive Care Med. 2016 Sep;42(9):1487-9. doi: 10.1007/s00134-016-4429-x. Epub 2016 Jul 4. Review. No abstract available.


Quantifying unintended exposure to high tidal volumes from breath stacking dyssynchrony in ARDS: the BREATHE criteria.

Beitler JR, Sands SA, Loring SH, Owens RL, Malhotra A, Spragg RG, Matthay MA, Thompson BT, Talmor D.

Intensive Care Med. 2016 Sep;42(9):1427-36. doi: 10.1007/s00134-016-4423-3. Epub 2016 Jun 24.


Esophageal and transpulmonary pressure in the clinical setting: meaning, usefulness and perspectives.

Mauri T, Yoshida T, Bellani G, Goligher EC, Carteaux G, Rittayamai N, Mojoli F, Chiumello D, Piquilloud L, Grasso S, Jubran A, Laghi F, Magder S, Pesenti A, Loring S, Gattinoni L, Talmor D, Blanch L, Amato M, Chen L, Brochard L, Mancebo J; PLeUral pressure working Group (PLUG—Acute Respiratory Failure section of the European Society of Intensive Care Medicine).

Intensive Care Med. 2016 Sep;42(9):1360-73. doi: 10.1007/s00134-016-4400-x. Epub 2016 Jun 22. Review.


Mortality and pulmonary mechanics in relation to respiratory system and transpulmonary driving pressures in ARDS.

Baedorf Kassis E, Loring SH, Talmor D.

Intensive Care Med. 2016 Aug;42(8):1206-13. doi: 10.1007/s00134-016-4403-7. Epub 2016 Jun 18.


Predicting Mortality in Low-Income Country ICUs: The Rwanda Mortality Probability Model (R-MPM).

Riviello ED, Kiviri W, Fowler RA, Mueller A, Novack V, Banner-Goodspeed VM, Weinkauf JL, Talmor DS, Twagirumugabe T.

PLoS One. 2016 May 19;11(5):e0155858. doi: 10.1371/journal.pone.0155858. eCollection 2016.


Effect of Aspirin on Development of ARDS in At-Risk Patients Presenting to the Emergency Department: The LIPS-A Randomized Clinical Trial.

Kor DJ, Carter RE, Park PK, Festic E, Banner-Goodspeed VM, Hinds R, Talmor D, Gajic O, Ware LB, Gong MN; US Critical Illness and Injury Trials Group: Lung Injury Prevention with Aspirin Study Group (USCIITG: LIPS-A).

JAMA. 2016 Jun 14;315(22):2406-14. doi: 10.1001/jama.2016.6330. Erratum in: JAMA. 2016 Sep 13;316(10):1116.


Cost effectiveness of intensive care in a low resource setting: A prospective cohort of medical critically ill patients.

Cubro H, Somun-Kapetanovic R, Thiery G, Talmor D, Gajic O.

World J Crit Care Med. 2016 May 4;5(2):150-64. doi: 10.5492/wjccm.v5.i2.150. eCollection 2016 May 4.


Circulating Antiangiogenic Factors and Myocardial Dysfunction in Hypertensive Disorders of Pregnancy.

Shahul S, Medvedofsky D, Wenger JB, Nizamuddin J, Brown SM, Bajracharya S, Salahuddin S, Thadhani R, Mueller A, Tung A, Lang RM, Arany Z, Talmor D, Karumanchi SA, Rana S.

Hypertension. 2016 Jun;67(6):1273-80. doi: 10.1161/HYPERTENSIONAHA.116.07252. Epub 2016 Apr 25.


Association between driving pressure and development of postoperative pulmonary complications in patients undergoing mechanical ventilation for general anaesthesia: a meta-analysis of individual patient data.

Neto AS, Hemmes SN, Barbas CS, Beiderlinden M, Fernandez-Bustamante A, Futier E, Gajic O, El-Tahan MR, Ghamdi AA, Günay E, Jaber S, Kokulu S, Kozian A, Licker M, Lin WQ, Maslow AD, Memtsoudis SG, Reis Miranda D, Moine P, Ng T, Paparella D, Ranieri VM, Scavonetto F, Schilling T, Selmo G, Severgnini P, Sprung J, Sundar S, Talmor D, Treschan T, Unzueta C, Weingarten TN, Wolthuis EK, Wrigge H, Amato MB, Costa EL, de Abreu MG, Pelosi P, Schultz MJ; PROVE Network Investigators.

Lancet Respir Med. 2016 Apr;4(4):272-80. doi: 10.1016/S2213-2600(16)00057-6. Epub 2016 Mar 4. Review. Erratum in: Lancet Respir Med. 2016 Jun;4(6):e34.


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