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Items: 1 to 50 of 168

1.

UBE3A-mediated PTPA ubiquitination and degradation regulate PP2A activity and dendritic spine morphology.

Wang J, Lou SS, Wang T, Wu RJ, Li G, Zhao M, Lu B, Li YY, Zhang J, Cheng X, Shen Y, Wang X, Zhu ZC, Li MJ, Takumi T, Yang H, Yu X, Liao L, Xiong ZQ.

Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12500-12505. doi: 10.1073/pnas.1820131116. Epub 2019 Jun 3.

PMID:
31160454
2.

Recent genetic and functional insights in autism spectrum disorder.

Nakanishi M, Anderson MP, Takumi T.

Curr Opin Neurol. 2019 Aug;32(4):627-634. doi: 10.1097/WCO.0000000000000718.

PMID:
31135459
3.

Morphological Pattern and Classification of the Superficial Middle Cerebral Vein by Cadaver Dissections: An Embryological Viewpoint.

Imada Y, Kurisu K, Takumi T, Aoyama H, Sadatomo T, Migita K, Yuki K.

Neurol Med Chir (Tokyo). 2019 Jul 15;59(7):264-270. doi: 10.2176/nmc.oa.2018-0284. Epub 2019 May 11.

4.

Behavioral neuroscience of autism.

Takumi T, Tamada K, Hatanaka F, Nakai N, Bolton PF.

Neurosci Biobehav Rev. 2019 May 3. pii: S0149-7634(18)30372-5. doi: 10.1016/j.neubiorev.2019.04.012. [Epub ahead of print] Review.

PMID:
31059731
5.

Gene expression profile data of the developing small intestine of Id2-deficient mice.

Mori K, Tamada K, Kurooka H, Matsui M, Takumi T, Yokota Y.

Data Brief. 2019 Mar 15;24:103717. doi: 10.1016/j.dib.2019.103717. eCollection 2019 Jun.

6.

Fetal neural stem cells from a mouse model of 15q11-13 duplication syndrome exhibit altered differentiation into neurons and astrocytes.

Choi Y, Kim H, Choi M, Yang EJ, Takumi T, Kim HS.

J Pharmacol Sci. 2019 Mar;139(3):249-253. doi: 10.1016/j.jphs.2018.12.007. Epub 2018 Dec 28.

7.

UBE3A regulates the transcription of IRF, an antiviral immunity.

Furumai R, Tamada K, Liu X, Takumi T.

Hum Mol Genet. 2019 Jun 15;28(12):1947-1958. doi: 10.1093/hmg/ddz019.

PMID:
30690483
8.

Quantitative evaluation of incomplete preweaning lethality in mice by using the CRISPR/Cas9 system.

Nakamura T, Nakajima K, Ohnishi T, Yoshikawa T, Nakanishi M, Takumi T, Tsuboi T, Kato T.

Sci Rep. 2018 Oct 30;8(1):16025. doi: 10.1038/s41598-018-34270-5.

9.

Critical roles of serotonin-oxytocin interaction during the neonatal period in social behavior in 15q dup mice with autistic traits.

Nagano M, Takumi T, Suzuki H.

Sci Rep. 2018 Sep 12;8(1):13675. doi: 10.1038/s41598-018-32042-9.

10.

Common Defects of Spine Dynamics and Circuit Function in Neurodevelopmental Disorders: A Systematic Review of Findings From in Vivo Optical Imaging of Mouse Models.

Nakai N, Takumi T, Nakai J, Sato M.

Front Neurosci. 2018 Jun 19;12:412. doi: 10.3389/fnins.2018.00412. eCollection 2018. Review.

11.

Glutamate and GABA in autism spectrum disorder-a translational magnetic resonance spectroscopy study in man and rodent models.

Horder J, Petrinovic MM, Mendez MA, Bruns A, Takumi T, Spooren W, Barker GJ, Künnecke B, Murphy DG.

Transl Psychiatry. 2018 May 25;8(1):106. doi: 10.1038/s41398-018-0155-1.

12.

Validity of a Novel Method for Estimating Low-Density Lipoprotein Cholesterol Levels in Cardiovascular Disease Patients Treated with Statins.

Sonoda T, Takumi T, Miyata M, Kanda D, Kosedo I, Yoshino S, Ohishi M.

J Atheroscler Thromb. 2018 Jul 1;25(7):643-652. doi: 10.5551/jat.44396. Epub 2018 May 23.

13.

The choroid plexus is an important circadian clock component.

Myung J, Schmal C, Hong S, Tsukizawa Y, Rose P, Zhang Y, Holtzman MJ, De Schutter E, Herzel H, Bordyugov G, Takumi T.

Nat Commun. 2018 Mar 14;9(1):1062. doi: 10.1038/s41467-018-03507-2.

14.

Id2 Determines Intestinal Identity through Repression of the Foregut Transcription Factor Irx5.

Mori K, Nakamura H, Kurooka H, Miyachi H, Tamada K, Sugai M, Takumi T, Yokota Y.

Mol Cell Biol. 2018 Apr 16;38(9). pii: e00250-17. doi: 10.1128/MCB.00250-17. Print 2018 May 1.

15.

A novel role of the antitumor agent tricyclodecan-9-yl-xanthogenate as an open channel blocker of KCNQ1/KCNE1.

Wu M, Takemoto M, Luo H, Xu JJ, Lu MH, Kameyama M, Takumi T, Song WJ.

Eur J Pharmacol. 2018 Apr 5;824:99-107. doi: 10.1016/j.ejphar.2018.02.013. Epub 2018 Feb 10.

PMID:
29438706
16.

Postsynaptic density proteins and their involvement in neurodevelopmental disorders.

Kaizuka T, Takumi T.

J Biochem. 2018 Jun 1;163(6):447-455. doi: 10.1093/jb/mvy022. Review.

PMID:
29415158
17.

CNV biology in neurodevelopmental disorders.

Takumi T, Tamada K.

Curr Opin Neurobiol. 2018 Feb;48:183-192. doi: 10.1016/j.conb.2017.12.004. Epub 2018 Jan 11. Review.

18.

Identification of genes regulating GABAergic interneuron maturation.

Fukumoto K, Tamada K, Toya T, Nishino T, Yanagawa Y, Takumi T.

Neurosci Res. 2018 Sep;134:18-29. doi: 10.1016/j.neures.2017.11.010. Epub 2017 Dec 2.

PMID:
29203264
19.

Clinical prediction rule for neurological sequelae due to acute encephalopathy: a medical community-based validation study in Harima, Japan.

Sasaki K, Nagase H, Maruyama A, Fujita K, Nishiyama M, Tanaka T, Nukina S, Takumi T, Takenaka K, Oyazato Y, Nishiyama A, Kawata T, Saeki K, Takami Y, Satake-Inoue E, Iijima K, Morioka I, Uetani Y.

BMJ Open. 2017 Nov 9;7(11):e016675. doi: 10.1136/bmjopen-2017-016675.

20.

Correction: Functional significance of rare neuroligin 1 variants found in autism.

Nakanishi M, Nomura J, Ji X, Tamada K, Arai T, Takahashi E, Bućan M, Takumi T.

PLoS Genet. 2017 Oct 3;13(10):e1007035. doi: 10.1371/journal.pgen.1007035. eCollection 2017 Oct.

21.

Prospective Study on the Incidence of Cerebrovascular Disease After Coronary Angiography.

Tokushige A, Miyata M, Sonoda T, Kosedo I, Kanda D, Takumi T, Kumagae Y, Fukukura Y, Ohishi M.

J Atheroscler Thromb. 2018 Mar 1;25(3):224-232. doi: 10.5551/jat.41012. Epub 2017 Aug 30.

22.

Skeletal Site-specific Changes in Bone Mass in a Genetic Mouse Model for Human 15q11-13 Duplication Seen in Autism.

Lewis KE, Sharan K, Takumi T, Yadav VK.

Sci Rep. 2017 Aug 29;7(1):9902. doi: 10.1038/s41598-017-09921-8.

23.

Functional significance of rare neuroligin 1 variants found in autism.

Nakanishi M, Nomura J, Ji X, Tamada K, Arai T, Takahashi E, Bućan M, Takumi T.

PLoS Genet. 2017 Aug 25;13(8):e1006940. doi: 10.1371/journal.pgen.1006940. eCollection 2017 Aug. Erratum in: PLoS Genet. 2017 Oct 3;13(10 ):e1007035.

24.

All solution-processed micro-structured flexible electrodes for low-cost light-emitting pressure sensors fabrication.

Shimotsu R, Takumi T, Vohra V.

Sci Rep. 2017 Jul 31;7(1):6921. doi: 10.1038/s41598-017-07284-8.

25.

Serotonin rebalances cortical tuning and behavior linked to autism symptoms in 15q11-13 CNV mice.

Nakai N, Nagano M, Saitow F, Watanabe Y, Kawamura Y, Kawamoto A, Tamada K, Mizuma H, Onoe H, Watanabe Y, Monai H, Hirase H, Nakatani J, Inagaki H, Kawada T, Miyazaki T, Watanabe M, Sato Y, Okabe S, Kitamura K, Kano M, Hashimoto K, Suzuki H, Takumi T.

Sci Adv. 2017 Jun 21;3(6):e1603001. doi: 10.1126/sciadv.1603001. eCollection 2017 Jun.

26.

Potential contribution of tandem circadian enhancers to nonlinear oscillations in clock gene expression.

Tokuda IT, Okamoto A, Matsumura R, Takumi T, Akashi M.

Mol Biol Cell. 2017 Aug 15;28(17):2333-2342. doi: 10.1091/mbc.E17-02-0129. Epub 2017 Jun 21.

27.

Unusual semi-extractability as a hallmark of nuclear body-associated architectural noncoding RNAs.

Chujo T, Yamazaki T, Kawaguchi T, Kurosaka S, Takumi T, Nakagawa S, Hirose T.

EMBO J. 2017 May 15;36(10):1447-1462. doi: 10.15252/embj.201695848. Epub 2017 Apr 12.

28.

Behavioral and neuroanatomical analyses in a genetic mouse model of 2q13 duplication.

Kishimoto K, Nomura J, Ellegood J, Fukumoto K, Lerch JP, Moreno-De-Luca D, Bourgeron T, Tamada K, Takumi T.

Genes Cells. 2017 May;22(5):436-451. doi: 10.1111/gtc.12487. Epub 2017 Mar 29.

29.

Rodent models of genetic and chromosomal variations in psychiatric disorders.

Nomura J, Kannan G, Takumi T.

Psychiatry Clin Neurosci. 2017 Aug;71(8):508-517. doi: 10.1111/pcn.12524. Epub 2017 Apr 23. Review.

30.

Distinct Defects in Spine Formation or Pruning in Two Gene Duplication Mouse Models of Autism.

Wang M, Li H, Takumi T, Qiu Z, Xu X, Yu X, Bian WJ.

Neurosci Bull. 2017 Apr;33(2):143-152. doi: 10.1007/s12264-017-0111-8. Epub 2017 Mar 3.

31.

Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness.

Nishita M, Park SY, Nishio T, Kamizaki K, Wang Z, Tamada K, Takumi T, Hashimoto R, Otani H, Pazour GJ, Hsu VW, Minami Y.

Sci Rep. 2017 Jan 26;7(1):1. doi: 10.1038/s41598-016-0028-x.

32.

Network Dynamics Mediate Circadian Clock Plasticity.

Azzi A, Evans JA, Leise T, Myung J, Takumi T, Davidson AJ, Brown SA.

Neuron. 2017 Jan 18;93(2):441-450. doi: 10.1016/j.neuron.2016.12.022. Epub 2017 Jan 5.

33.

CHRONO integrates behavioral stress and epigenetic control of metabolism.

Hatanaka F, Takumi T.

Ann Med. 2017 Jun;49(4):352-356. doi: 10.1080/07853890.2016.1276301. Epub 2017 Jan 19. Review.

PMID:
28010116
34.

FUS/TLS acts as an aggregation-dependent modifier of polyglutamine disease model mice.

Kino Y, Washizu C, Kurosawa M, Yamada M, Doi H, Takumi T, Adachi H, Katsuno M, Sobue G, Hicks GG, Hattori N, Shimogori T, Nukina N.

Sci Rep. 2016 Oct 14;6:35236. doi: 10.1038/srep35236.

35.

Exome sequencing in the knockin mice generated using the CRISPR/Cas system.

Nakajima K, Kazuno AA, Kelsoe J, Nakanishi M, Takumi T, Kato T.

Sci Rep. 2016 Oct 4;6:34703. doi: 10.1038/srep34703.

36.

Structural, super-resolution microscopy analysis of paraspeckle nuclear body organization.

West JA, Mito M, Kurosaka S, Takumi T, Tanegashima C, Chujo T, Yanaka K, Kingston RE, Hirose T, Bond C, Fox A, Nakagawa S.

J Cell Biol. 2016 Sep 26;214(7):817-30. doi: 10.1083/jcb.201601071. Epub 2016 Sep 19.

37.

CHD8 haploinsufficiency results in autistic-like phenotypes in mice.

Katayama Y, Nishiyama M, Shoji H, Ohkawa Y, Kawamura A, Sato T, Suyama M, Takumi T, Miyakawa T, Nakayama KI.

Nature. 2016 Sep 29;537(7622):675-679. doi: 10.1038/nature19357. Epub 2016 Sep 7.

PMID:
27602517
38.

Regulation of membrane KCNQ1/KCNE1 channel density by sphingomyelin synthase 1.

Wu M, Takemoto M, Taniguchi M, Takumi T, Okazaki T, Song WJ.

Am J Physiol Cell Physiol. 2016 Jul 1;311(1):C15-23. doi: 10.1152/ajpcell.00272.2015. Epub 2016 May 18.

39.

Translocated in liposarcoma regulates the distribution and function of mammalian enabled, a modulator of actin dynamics.

Sugiura T, Matsuda S, Kurosaka S, Nakai N, Fukumoto K, Takahashi T, Maruyama H, Imaizumi K, Matsumoto M, Takumi T.

FEBS J. 2016 Apr;283(8):1475-87. doi: 10.1111/febs.13685. Epub 2016 Mar 2.

40.

Sequence features associated with the cleavage efficiency of CRISPR/Cas9 system.

Liu X, Homma A, Sayadi J, Yang S, Ohashi J, Takumi T.

Sci Rep. 2016 Jan 27;6:19675. doi: 10.1038/srep19675.

41.

Angiotensin-Converting Enzyme Inhibitor Prevents the Worsening of Renal Function in the Late Phase after Percutaneous Coronary Intervention.

Kanda D, Takumi T, Miyata M, Tokushige A, Sonoda T, Yoshino S, Saihara K, Ohishi M.

J Atheroscler Thromb. 2016;23(2):233-40. doi: 10.5551/jat.33266. Epub 2015 Dec 19.

42.

Physiological Assessment in Peripheral Artery Disease: Going Beyond Angiography.

Takumi T, Miyata M, Ohishi M.

J Atheroscler Thromb. 2016;23(1):44-5. doi: 10.5551/jat.ED026. Epub 2015 Nov 11. No abstract available.

43.

Transcriptome profiling of white adipose tissue in a mouse model for 15q duplication syndrome.

Liu X, Tamada K, Kishimoto R, Okubo H, Ise S, Ohta H, Ruf S, Nakatani J, Kohno N, Spitz F, Takumi T.

Genom Data. 2015 Jul 10;5:394-6. doi: 10.1016/j.gdata.2015.06.035. eCollection 2015 Sep.

44.

Constant light enhances synchrony among circadian clock cells and promotes behavioral rhythms in VPAC2-signaling deficient mice.

Hughes AT, Croft CL, Samuels RE, Myung J, Takumi T, Piggins HD.

Sci Rep. 2015 Sep 15;5:14044. doi: 10.1038/srep14044.

45.

Autism spectrum disorder model mice: Focus on copy number variation and epigenetics.

Nakai N, Otsuka S, Myung J, Takumi T.

Sci China Life Sci. 2015 Oct;58(10):976-84. doi: 10.1007/s11427-015-4891-7. Review.

PMID:
26335737
46.

DEC2-E4BP4 Heterodimer Represses the Transcriptional Enhancer Activity of the EE Element in the Per2 Promoter.

Tanoue S, Fujimoto K, Myung J, Hatanaka F, Kato Y, Takumi T.

Front Neurol. 2015 Jul 23;6:166. doi: 10.3389/fneur.2015.00166. eCollection 2015.

47.

Cerebellar associative sensory learning defects in five mouse autism models.

Kloth AD, Badura A, Li A, Cherskov A, Connolly SG, Giovannucci A, Bangash MA, Grasselli G, Peñagarikano O, Piochon C, Tsai PT, Geschwind DH, Hansel C, Sahin M, Takumi T, Worley PF, Wang SS.

Elife. 2015 Jul 9;4:e06085. doi: 10.7554/eLife.06085.

48.

Distinct roles for GABA across multiple timescales in mammalian circadian timekeeping.

DeWoskin D, Myung J, Belle MD, Piggins HD, Takumi T, Forger DB.

Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):E3911-9. doi: 10.1073/pnas.1420753112. Epub 2015 Jun 30.

49.

GABA-mediated repulsive coupling between circadian clock neurons in the SCN encodes seasonal time.

Myung J, Hong S, DeWoskin D, De Schutter E, Forger DB, Takumi T.

Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):E3920-9. doi: 10.1073/pnas.1421200112. Epub 2015 Jun 30.

50.

Role for neonatal D-serine signaling: prevention of physiological and behavioral deficits in adult Pick1 knockout mice.

Nomura J, Jaaro-Peled H, Lewis E, Nuñez-Abades P, Huppe-Gourgues F, Cash-Padgett T, Emiliani F, Kondo MA, Furuya A, Landek-Salgado MA, Ayhan Y, Kamiya A, Takumi T, Huganir R, Pletnikov M, O'Donnell P, Sawa A.

Mol Psychiatry. 2016 Mar;21(3):386-93. doi: 10.1038/mp.2015.61. Epub 2015 May 26.

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