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Items: 1 to 50 of 75

1.

Differential transactivation of the upstream aggrecan enhancer regulated by PAX1/9 depends on SOX9-driven transactivation.

Takimoto A, Kokubu C, Watanabe H, Sakuma T, Yamamoto T, Kondoh G, Hiraki Y, Shukunami C.

Sci Rep. 2019 Mar 14;9(1):4605. doi: 10.1038/s41598-019-40810-4.

2.

Development of Recombinant Methioninase for Cancer Treatment.

Hoffman RM, Tan Y, Li S, Han Q, Yagi S, Takakura T, Takimoto A, Inagaki K, Kudou D.

Methods Mol Biol. 2019;1866:107-131. doi: 10.1007/978-1-4939-8796-2_10.

PMID:
30725412
3.

Scleraxis is a transcriptional activator that regulates the expression of Tenomodulin, a marker of mature tenocytes and ligamentocytes.

Shukunami C, Takimoto A, Nishizaki Y, Yoshimoto Y, Tanaka S, Miura S, Watanabe H, Sakuma T, Yamamoto T, Kondoh G, Hiraki Y.

Sci Rep. 2018 Feb 16;8(1):3155. doi: 10.1038/s41598-018-21194-3.

4.

Molecular characterization and function of tenomodulin, a marker of tendons and ligaments that integrate musculoskeletal components.

Shukunami C, Yoshimoto Y, Takimoto A, Yamashita H, Hiraki Y.

Jpn Dent Sci Rev. 2016 Nov;52(4):84-92. doi: 10.1016/j.jdsr.2016.04.003. Epub 2016 Apr 27. Review.

5.

Sewing needles in the abdominal cavity assumed to have been ingested and to have penetrated the GI tract 40 years ago: A case report.

Yamaguchi N, Hiramatsu K, Shibata Y, Yoshihara M, Aoba T, Kamiya T, Koike Y, Fujita T, Maeda C, Ito K, Kanbara Y, Nishimura M, Kobayashi R, Dei H, Takimoto A, Nonaka Y, Kato T.

Asian J Endosc Surg. 2017 Nov;10(4):446-449. doi: 10.1111/ases.12375. Epub 2017 Mar 28.

PMID:
28349649
6.

Scleraxis is required for maturation of tissue domains for proper integration of the musculoskeletal system.

Yoshimoto Y, Takimoto A, Watanabe H, Hiraki Y, Kondoh G, Shukunami C.

Sci Rep. 2017 Mar 22;7:45010. doi: 10.1038/srep45010.

7.

Third-party social evaluations of humans by monkeys and dogs.

Anderson JR, Bucher B, Chijiiwa H, Kuroshima H, Takimoto A, Fujita K.

Neurosci Biobehav Rev. 2017 Nov;82:95-109. doi: 10.1016/j.neubiorev.2017.01.003. Epub 2017 Jan 7. Review.

PMID:
28077260
8.

A new diatom growth inhibition assay using the XTT colorimetric method.

Jiang W, Akagi T, Suzuki H, Takimoto A, Nagai H.

Comp Biochem Physiol C Toxicol Pharmacol. 2016 Jul-Aug;185-186:13-19. doi: 10.1016/j.cbpc.2016.02.004. Epub 2016 Mar 3.

PMID:
26945522
9.

Functional Investigation of a Non-coding Variant Associated with Adolescent Idiopathic Scoliosis in Zebrafish: Elevated Expression of the Ladybird Homeobox Gene Causes Body Axis Deformation.

Guo L, Yamashita H, Kou I, Takimoto A, Meguro-Horike M, Horike S, Sakuma T, Miura S, Adachi T, Yamamoto T, Ikegawa S, Hiraki Y, Shukunami C.

PLoS Genet. 2016 Jan 28;12(1):e1005802. doi: 10.1371/journal.pgen.1005802. eCollection 2016 Jan.

10.

[Expected Duties of Pharmacists and Potential Needs of Physicians and Nurses on a Kaifukuki Rehabilitation Ward].

Fujihara H, Koinuma M, Yumoto T, Maeda T, Kamite M, Kawahara E, Soeda S, Takimoto A, Tamura K, Nakamura M, Kaneta M, Takao Y, Saito M, Kagaya H, Murayama J.

Yakugaku Zasshi. 2015;135(8):969-75. doi: 10.1248/yakushi.15-00065. Japanese.

11.

Scleraxis and osterix antagonistically regulate tensile force-responsive remodeling of the periodontal ligament and alveolar bone.

Takimoto A, Kawatsu M, Yoshimoto Y, Kawamoto T, Seiryu M, Takano-Yamamoto T, Hiraki Y, Shukunami C.

Development. 2015 Feb 15;142(4):787-96. doi: 10.1242/dev.116228.

12.

The evolution of self-control.

MacLean EL, Hare B, Nunn CL, Addessi E, Amici F, Anderson RC, Aureli F, Baker JM, Bania AE, Barnard AM, Boogert NJ, Brannon EM, Bray EE, Bray J, Brent LJ, Burkart JM, Call J, Cantlon JF, Cheke LG, Clayton NS, Delgado MM, DiVincenti LJ, Fujita K, Herrmann E, Hiramatsu C, Jacobs LF, Jordan KE, Laude JR, Leimgruber KL, Messer EJ, Moura AC, Ostojić L, Picard A, Platt ML, Plotnik JM, Range F, Reader SM, Reddy RB, Sandel AA, Santos LR, Schumann K, Seed AM, Sewall KB, Shaw RC, Slocombe KE, Su Y, Takimoto A, Tan J, Tao R, van Schaik CP, Virányi Z, Visalberghi E, Wade JC, Watanabe A, Widness J, Young JK, Zentall TR, Zhao Y.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):E2140-8. doi: 10.1073/pnas.1323533111. Epub 2014 Apr 21.

13.

The N-terminal cleavage of chondromodulin-I in growth-plate cartilage at the hypertrophic and calcified zones during bone development.

Miura S, Kondo J, Takimoto A, Sano-Takai H, Guo L, Shukunami C, Tanaka H, Hiraki Y.

PLoS One. 2014 Apr 7;9(4):e94239. doi: 10.1371/journal.pone.0094239. eCollection 2014.

14.

Pax1 acts as a negative regulator of chondrocyte maturation.

Takimoto A, Mohri H, Kokubu C, Hiraki Y, Shukunami C.

Exp Cell Res. 2013 Dec 10;319(20):3128-39. doi: 10.1016/j.yexcr.2013.09.015. Epub 2013 Sep 27.

PMID:
24080012
15.

Genetic variants in GPR126 are associated with adolescent idiopathic scoliosis.

Kou I, Takahashi Y, Johnson TA, Takahashi A, Guo L, Dai J, Qiu X, Sharma S, Takimoto A, Ogura Y, Jiang H, Yan H, Kono K, Kawakami N, Uno K, Ito M, Minami S, Yanagida H, Taneichi H, Hosono N, Tsuji T, Suzuki T, Sudo H, Kotani T, Yonezawa I, Londono D, Gordon D, Herring JA, Watanabe K, Chiba K, Kamatani N, Jiang Q, Hiraki Y, Kubo M, Toyama Y, Tsunoda T, Wise CA, Qiu Y, Shukunami C, Matsumoto M, Ikegawa S.

Nat Genet. 2013 Jun;45(6):676-9. doi: 10.1038/ng.2639. Epub 2013 May 12.

PMID:
23666238
16.

Scx+/Sox9+ progenitors contribute to the establishment of the junction between cartilage and tendon/ligament.

Sugimoto Y, Takimoto A, Akiyama H, Kist R, Scherer G, Nakamura T, Hiraki Y, Shukunami C.

Development. 2013 Jun;140(11):2280-8. doi: 10.1242/dev.096354. Epub 2013 Apr 24.

17.

Third-party social evaluation of humans by monkeys.

Anderson JR, Kuroshima H, Takimoto A, Fujita K.

Nat Commun. 2013;4:1561. doi: 10.1038/ncomms2495.

PMID:
23463004
18.

Capuchin monkeys judge third-party reciprocity.

Anderson JR, Takimoto A, Kuroshima H, Fujita K.

Cognition. 2013 Apr;127(1):140-6. doi: 10.1016/j.cognition.2012.12.007. Epub 2013 Jan 31.

PMID:
23376298
19.

Generation and characterization of ScxCre transgenic mice.

Sugimoto Y, Takimoto A, Hiraki Y, Shukunami C.

Genesis. 2013 Apr;51(4):275-83. doi: 10.1002/dvg.22372. Epub 2013 Mar 13.

PMID:
23349075
20.

Breed Differences in Dopamine Receptor D4 Gene (DRD4) in Horses.

Hori Y, Ozaki T, Yamada Y, Tozaki T, Kim HS, Takimoto A, Endo M, Manabe N, Inoue-Murayama M, Fujita K.

J Equine Sci. 2013;24(3):31-6. doi: 10.1294/jes.24.31. Epub 2013 Sep 30.

21.

Direct conversion of tenocytes into chondrocytes by Sox9.

Takimoto A, Oro M, Hiraki Y, Shukunami C.

Exp Cell Res. 2012 Aug 1;318(13):1492-507. doi: 10.1016/j.yexcr.2012.04.002. Epub 2012 Apr 10.

PMID:
22510437
22.

The influences of various anthropogenic sources of deterioration on meiobenthos (Ostracoda) over the last 100 years in Suo-Nada in the Seto Inland Sea, southwest Japan.

Irizuki T, Takimoto A, Sako M, Nomura R, Kakuno K, Wanishi A, Kawano S.

Mar Pollut Bull. 2011 Oct;62(10):2030-41. doi: 10.1016/j.marpolbul.2011.08.005. Epub 2011 Aug 31.

PMID:
21885072
23.

I acknowledge your help: capuchin monkeys' sensitivity to others' labor.

Takimoto A, Fujita K.

Anim Cogn. 2011 Sep;14(5):715-25. doi: 10.1007/s10071-011-0406-5. Epub 2011 Apr 26.

PMID:
21519900
24.

Stimulatory actions of lysophosphatidic acid on mouse ATDC5 chondroprogenitor cells.

Itoh R, Miura S, Takimoto A, Kondo S, Sano H, Hiraki Y.

J Bone Miner Metab. 2010 Nov;28(6):659-71. doi: 10.1007/s00774-010-0184-1. Epub 2010 May 11.

PMID:
20458606
25.

Differential expression of Tenomodulin and Chondromodulin-1 at the insertion site of the tendon reflects a phenotypic transition of the resident cells.

Yukata K, Matsui Y, Shukunami C, Takimoto A, Hirohashi N, Ohtani O, Kimura T, Hiraki Y, Yasui N.

Tissue Cell. 2010 Apr;42(2):116-20. doi: 10.1016/j.tice.2010.02.002. Epub 2010 Mar 23.

PMID:
20334886
26.

Capuchin monkeys (Cebus apella) are sensitive to others' reward: an experimental analysis of food-choice for conspecifics.

Takimoto A, Kuroshima H, Fujita K.

Anim Cogn. 2010 Mar;13(2):249-61. doi: 10.1007/s10071-009-0262-8. Epub 2009 Jul 17.

PMID:
19609580
27.

Differential actions of VEGF-A isoforms on perichondrial angiogenesis during endochondral bone formation.

Takimoto A, Nishizaki Y, Hiraki Y, Shukunami C.

Dev Biol. 2009 Aug 15;332(2):196-211. doi: 10.1016/j.ydbio.2009.05.552. Epub 2009 May 21.

28.

Chemoenzymatic synthesis of glycosylated glucagon-like peptide 1: effect of glycosylation on proteolytic resistance and in vivo blood glucose-lowering activity.

Ueda T, Tomita K, Notsu Y, Ito T, Fumoto M, Takakura T, Nagatome H, Takimoto A, Mihara S, Togame H, Kawamoto K, Iwasaki T, Asakura K, Oshima T, Hanasaki K, Nishimura S, Kondo H.

J Am Chem Soc. 2009 May 6;131(17):6237-45. doi: 10.1021/ja900261g.

PMID:
19361194
29.

Superovulation and embryo transfer in Holstein cattle using sexed sperm.

Hayakawa H, Hirai T, Takimoto A, Ideta A, Aoyagi Y.

Theriogenology. 2009 Jan 1;71(1):68-73. doi: 10.1016/j.theriogenology.2008.09.016. Epub 2008 Oct 31.

PMID:
18951623
30.

Altered fracture callus formation in chondromodulin-I deficient mice.

Yukata K, Matsui Y, Shukunami C, Takimoto A, Goto T, Nishizaki Y, Nakamichi Y, Kubo T, Sano T, Kato S, Hiraki Y, Yasui N.

Bone. 2008 Dec;43(6):1047-56. doi: 10.1016/j.bone.2008.08.111. Epub 2008 Aug 22.

PMID:
18793763
31.

Chondromodulin-I and tenomodulin are differentially expressed in the avascular mesenchyme during mouse and chick development.

Shukunami C, Takimoto A, Miura S, Nishizaki Y, Hiraki Y.

Cell Tissue Res. 2008 Apr;332(1):111-22. doi: 10.1007/s00441-007-0570-8. Epub 2008 Feb 1.

PMID:
18239943
32.

Reverse glycoblotting allows rapid-enrichment glycoproteomics of biopharmaceuticals and disease-related biomarkers.

Kurogochi M, Amano M, Fumoto M, Takimoto A, Kondo H, Nishimura S.

Angew Chem Int Ed Engl. 2007;46(46):8808-13. No abstract available.

PMID:
17943939
33.

Quantitative glycomics of human whole serum glycoproteins based on the standardized protocol for liberating N-glycans.

Kita Y, Miura Y, Furukawa J, Nakano M, Shinohara Y, Ohno M, Takimoto A, Nishimura S.

Mol Cell Proteomics. 2007 Aug;6(8):1437-45. Epub 2007 May 23.

34.

Detection and genotyping of Cryptosporidium from brown rats (Rattus norvegicus) captured in an urban area of Japan.

Kimura A, Edagawa A, Okada K, Takimoto A, Yonesho S, Karanis P.

Parasitol Res. 2007 May;100(6):1417-20. Epub 2007 Feb 21.

PMID:
17318580
35.

Structure of the antitumour enzyme L-methionine gamma-lyase from Pseudomonas putida at 1.8 A resolution.

Kudou D, Misaki S, Yamashita M, Tamura T, Takakura T, Yoshioka T, Yagi S, Hoffman RM, Takimoto A, Esaki N, Inagaki K.

J Biochem. 2007 Apr;141(4):535-44. Epub 2007 Feb 8.

PMID:
17289792
36.

Scleraxis positively regulates the expression of tenomodulin, a differentiation marker of tenocytes.

Shukunami C, Takimoto A, Oro M, Hiraki Y.

Dev Biol. 2006 Oct 1;298(1):234-47. Epub 2006 Jun 27.

37.

Physicochemical and pharmacokinetic characterization of highly potent recombinant L-methionine gamma-lyase conjugated with polyethylene glycol as an antitumor agent.

Takakura T, Takimoto A, Notsu Y, Yoshida H, Ito T, Nagatome H, Ohno M, Kobayashi Y, Yoshioka T, Inagaki K, Yagi S, Hoffman RM, Esaki N.

Cancer Res. 2006 Mar 1;66(5):2807-14.

38.

High-level expression, purification, and some properties of a recombinant cephalosporin-C deacetylase.

Takimoto A, Yagi S, Mitsushima K.

J Biosci Bioeng. 1999;87(4):456-62.

PMID:
16232499
39.

Molecular design of glycoprotein mimetics: glycoblotting by engineered proteins with an oxylamino-functionalized amino acid residue.

Matsubara N, Oiwa K, Hohsaka T, Sadamoto R, Niikura K, Fukuhara N, Takimoto A, Kondo H, Nishimura S.

Chemistry. 2005 Nov 18;11(23):6974-81.

PMID:
16144022
40.

Combinatorial synthesis of MUC1 glycopeptides: polymer blotting facilitates chemical and enzymatic synthesis of highly complicated mucin glycopeptides.

Fumoto M, Hinou H, Ohta T, Ito T, Yamada K, Takimoto A, Kondo H, Shimizu H, Inazu T, Nakahara Y, Nishimura S.

J Am Chem Soc. 2005 Aug 24;127(33):11804-18.

PMID:
16104759
41.

High-level expression and bulk crystallization of recombinant L-methionine gamma-lyase, an anticancer agent.

Takakura T, Ito T, Yagi S, Notsu Y, Itakura T, Nakamura T, Inagaki K, Esaki N, Hoffman RM, Takimoto A.

Appl Microbiol Biotechnol. 2006 Mar;70(2):183-92. Epub 2005 Jul 13.

PMID:
16012835
42.

Molecular transporter between polymer platforms: highly efficient chemoenzymatic glycopeptide synthesis by the combined use of solid-phase and water-soluble polymer supports.

Fumoto M, Hinou H, Matsushita T, Kurogochi M, Ohta T, Ito T, Yamada K, Takimoto A, Kondo H, Inazu T, Nishimura S.

Angew Chem Int Ed Engl. 2005 Apr 22;44(17):2534-7. No abstract available.

PMID:
15786520
43.

PEGylation confers greatly extended half-life and attenuated immunogenicity to recombinant methioninase in primates.

Yang Z, Wang J, Lu Q, Xu J, Kobayashi Y, Takakura T, Takimoto A, Yoshioka T, Lian C, Chen C, Zhang D, Zhang Y, Li S, Sun X, Tan Y, Yagi S, Frenkel EP, Hoffman RM.

Cancer Res. 2004 Sep 15;64(18):6673-8.

44.

Circulating half-life of PEGylated recombinant methioninase holoenzyme is highly dose dependent on cofactor pyridoxal-5'-phosphate.

Yang Z, Sun X, Li S, Tan Y, Wang X, Zhang N, Yagi S, Takakura T, Kobayashi Y, Takimoto A, Yoshioka T, Suginaka A, Frenkel EP, Hoffman RM.

Cancer Res. 2004 Aug 15;64(16):5775-8.

45.

Microscopic liver metastasis: prognostic factor for patients with pT2 gallbladder carcinoma.

Endo I, Shimada H, Takimoto A, Fujii Y, Miura Y, Sugita M, Morioka D, Masunari H, Tanaka K, Sekido H, Togo S.

World J Surg. 2004 Jul;28(7):692-6. Epub 2004 Jun 4.

PMID:
15175901
46.

Batch production of deacetyl 7-aminocephalosporanic acid by immobilized cephalosporin-C deacetylase.

Takimoto A, Takakura T, Tani H, Yagi S, Mitsushima K.

Appl Microbiol Biotechnol. 2004 Aug;65(3):263-7. Epub 2004 Apr 7.

PMID:
15069587
47.

Assay method for antitumor L-methionine gamma-lyase: comprehensive kinetic analysis of the complex reaction with L-methionine.

Takakura T, Mitsushima K, Yagi S, Inagaki K, Tanaka H, Esaki N, Soda K, Takimoto A.

Anal Biochem. 2004 Apr 15;327(2):233-40.

PMID:
15051540
48.

In vivo efficacy of recombinant methioninase is enhanced by the combination of polyethylene glycol conjugation and pyridoxal 5'-phosphate supplementation.

Sun X, Yang Z, Li S, Tan Y, Zhang N, Wang X, Yagi S, Yoshioka T, Takimoto A, Mitsushima K, Suginaka A, Frenkel EP, Hoffman RM.

Cancer Res. 2003 Dec 1;63(23):8377-83.

49.

Functional analysis of recombinant pancreatic secretory trypsin inhibitor protein with amino-acid substitution.

Kuwata K, Hirota M, Shimizu H, Nakae M, Nishihara S, Takimoto A, Mitsushima K, Kikuchi N, Endo K, Inoue M, Ogawa M.

J Gastroenterol. 2002;37(11):928-34.

PMID:
12483248
50.

Large-scale production of functional human adrenomedullin: expression, cleavage, amidation, and purification.

Mitsuda Y, Takimoto A, Kamitani S, Kitamura K, Sakata T, Mitsushima K.

Protein Expr Purif. 2002 Aug;25(3):448-55.

PMID:
12182825

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