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Items: 1 to 50 of 330

1.

Live-Cell Imaging of Protein Degradation Utilizing Designed Protein-Tag Mutant and Fluorescent Probe with Turn-Off Switch.

Gao J, Hori Y, Takeuchi O, Kikuchi K.

Bioconjug Chem. 2020 Jan 9. doi: 10.1021/acs.bioconjchem.9b00696. [Epub ahead of print]

PMID:
31877021
2.

Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis.

Kakiuchi N, Yoshida K, Uchino M, Kihara T, Akaki K, Inoue Y, Kawada K, Nagayama S, Yokoyama A, Yamamoto S, Matsuura M, Horimatsu T, Hirano T, Goto N, Takeuchi Y, Ochi Y, Shiozawa Y, Kogure Y, Watatani Y, Fujii Y, Kim SK, Kon A, Kataoka K, Yoshizato T, Nakagawa MM, Yoda A, Nanya Y, Makishima H, Shiraishi Y, Chiba K, Tanaka H, Sanada M, Sugihara E, Sato TA, Maruyama T, Miyoshi H, Taketo MM, Oishi J, Inagaki R, Ueda Y, Okamoto S, Okajima H, Sakai Y, Sakurai T, Haga H, Hirota S, Ikeuchi H, Nakase H, Marusawa H, Chiba T, Takeuchi O, Miyano S, Seno H, Ogawa S.

Nature. 2020 Jan;577(7789):260-265. doi: 10.1038/s41586-019-1856-1. Epub 2019 Dec 18.

PMID:
31853061
3.

Prexasertib increases the sensitivity of pancreatic cancer cells to gemcitabine and S‑1.

Morimoto Y, Takada K, Takeuchi O, Takagi A, Watanabe K, Hirohara M, Hamamoto T, Masuda Y.

Oncol Rep. 2020 Feb;43(2):689-699. doi: 10.3892/or.2019.7421. Epub 2019 Nov 28.

PMID:
31789403
4.

Codon bias confers stability to human mRNAs.

Hia F, Yang SF, Shichino Y, Yoshinaga M, Murakawa Y, Vandenbon A, Fukao A, Fujiwara T, Landthaler M, Natsume T, Adachi S, Iwasaki S, Takeuchi O.

EMBO Rep. 2019 Nov 5;20(11):e48220. doi: 10.15252/embr.201948220. Epub 2019 Sep 3.

PMID:
31482640
5.

NET-CAGE characterizes the dynamics and topology of human transcribed cis-regulatory elements.

Hirabayashi S, Bhagat S, Matsuki Y, Takegami Y, Uehata T, Kanemaru A, Itoh M, Shirakawa K, Takaori-Kondo A, Takeuchi O, Carninci P, Katayama S, Hayashizaki Y, Kere J, Kawaji H, Murakawa Y.

Nat Genet. 2019 Sep;51(9):1369-1379. doi: 10.1038/s41588-019-0485-9. Epub 2019 Sep 2.

PMID:
31477927
6.

RNA binding proteins in the control of autoimmune diseases.

Yoshinaga M, Takeuchi O.

Immunol Med. 2019 Jun;42(2):53-64. doi: 10.1080/25785826.2019.1655192. Epub 2019 Aug 26.

PMID:
31449478
7.

Translation-dependent unwinding of stem-loops by UPF1 licenses Regnase-1 to degrade inflammatory mRNAs.

Mino T, Iwai N, Endo M, Inoue K, Akaki K, Hia F, Uehata T, Emura T, Hidaka K, Suzuki Y, Standley DM, Okada-Hatakeyama M, Ohno S, Sugiyama H, Yamashita A, Takeuchi O.

Nucleic Acids Res. 2019 Sep 19;47(16):8838-8859. doi: 10.1093/nar/gkz628.

PMID:
31329944
8.

Post-transcriptional control of immune responses and its potential application.

Yoshinaga M, Takeuchi O.

Clin Transl Immunology. 2019 Jun 17;8(6):e1063. doi: 10.1002/cti2.1063. eCollection 2019. Review.

9.

Continuous Heteroepitaxy of Two-Dimensional Heterostructures Based on Layered Chalcogenides.

Kobayashi Y, Yoshida S, Maruyama M, Mogi H, Murase K, Maniwa Y, Takeuchi O, Okada S, Shigekawa H, Miyata Y.

ACS Nano. 2019 Jul 23;13(7):7527-7535. doi: 10.1021/acsnano.8b07991. Epub 2019 Jun 20.

PMID:
31149797
10.

N4BP1 restricts HIV-1 and its inactivation by MALT1 promotes viral reactivation.

Yamasoba D, Sato K, Ichinose T, Imamura T, Koepke L, Joas S, Reith E, Hotter D, Misawa N, Akaki K, Uehata T, Mino T, Miyamoto S, Noda T, Yamashita A, Standley DM, Kirchhoff F, Sauter D, Koyanagi Y, Takeuchi O.

Nat Microbiol. 2019 Sep;4(9):1532-1544. doi: 10.1038/s41564-019-0460-3. Epub 2019 May 27.

PMID:
31133753
11.

Evolution of local conductance pathways in a single-molecule junction studied using the three-dimensional dynamic probe method.

Taninaka A, Yoshida S, Sugita Y, Takeuchi O, Shigekawa H.

Nanoscale. 2019 Mar 28;11(13):5951-5959. doi: 10.1039/c9nr00717b.

PMID:
30869706
12.

Surface-mediated spin dynamics probed by optical-pump-probe scanning tunneling microscopy.

Wang ZH, Yoon CH, Yoshida S, Arashida Y, Takeuchi O, Ohno Y, Shigekawa H.

Phys Chem Chem Phys. 2019 Apr 3;21(14):7256-7260. doi: 10.1039/c8cp07786j.

PMID:
30724922
13.

Individualized treatment based on CYP3A5 single-nucleotide polymorphisms with tacrolimus in ulcerative colitis.

Okabayashi S, Kobayashi T, Saito E, Toyonaga T, Ozaki R, Sagami S, Nakano M, Tanaka J, Yagisawa K, Kuronuma S, Takeuchi O, Hibi T.

Intest Res. 2019 Apr;17(2):218-226. doi: 10.5217/ir.2018.00117. Epub 2019 Feb 7.

14.

Mechanisms of metformin's anti‑tumor activity against gemcitabine‑resistant pancreatic adenocarcinoma.

Suzuki K, Takeuchi O, Suzuki Y, Kitagawa Y.

Int J Oncol. 2019 Feb;54(2):764-772. doi: 10.3892/ijo.2018.4662. Epub 2018 Dec 10.

PMID:
30570108
15.

Hassall's corpuscles with cellular-senescence features maintain IFNα production through neutrophils and pDC activation in the thymus.

Wang J, Sekai M, Matsui T, Fujii Y, Matsumoto M, Takeuchi O, Minato N, Hamazaki Y.

Int Immunol. 2019 Mar 5;31(3):127-139. doi: 10.1093/intimm/dxy073.

PMID:
30534943
16.

Translation of Hepatitis A Virus IRES Is Upregulated by a Hepatic Cell-Specific Factor.

Sadahiro A, Fukao A, Kosaka M, Funakami Y, Takizawa N, Takeuchi O, Duncan KE, Fujiwara T.

Front Genet. 2018 Aug 10;9:307. doi: 10.3389/fgene.2018.00307. eCollection 2018.

17.

Post-transcriptional regulation of immune responses by RNA binding proteins.

Mino T, Takeuchi O.

Proc Jpn Acad Ser B Phys Biol Sci. 2018;94(6):248-258. doi: 10.2183/pjab.94.017. Review.

18.

A Simple 1-Day Colon Capsule Endoscopy Procedure Demonstrated to be a Highly Acceptable Monitoring Tool for Ulcerative Colitis.

Okabayashi S, Kobayashi T, Nakano M, Toyonaga T, Ozaki R, Tablante MC, Kuronuma S, Takeuchi O, Hibi T.

Inflamm Bowel Dis. 2018 Oct 12;24(11):2404-2412. doi: 10.1093/ibd/izy125.

PMID:
29718414
19.

Pulmonary Regnase-1 orchestrates the interplay of epithelium and adaptive immune systems to protect against pneumonia.

Nakatsuka Y, Vandenbon A, Mino T, Yoshinaga M, Uehata T, Cui X, Sato A, Tsujimura T, Suzuki Y, Sato A, Handa T, Chin K, Sawa T, Hirai T, Takeuchi O.

Mucosal Immunol. 2018 Jul;11(4):1203-1218. doi: 10.1038/s41385-018-0024-5. Epub 2018 Apr 25.

PMID:
29695841
20.

The effect of nitrogen lone-pair interaction on the conduction in a single-molecule junction with amine-Au bonding.

Sugita Y, Taninaka A, Yoshida S, Takeuchi O, Shigekawa H.

Sci Rep. 2018 Mar 27;8(1):5222. doi: 10.1038/s41598-018-22893-7.

21.

NSD3 keeps IRF3 active.

Mino T, Takeuchi O.

J Exp Med. 2017 Dec 4;214(12):3475-3476. doi: 10.1084/jem.20171980. Epub 2017 Nov 20.

22.

Regnase-1 and Roquin Nonredundantly Regulate Th1 Differentiation Causing Cardiac Inflammation and Fibrosis.

Cui X, Mino T, Yoshinaga M, Nakatsuka Y, Hia F, Yamasoba D, Tsujimura T, Tomonaga K, Suzuki Y, Uehata T, Takeuchi O.

J Immunol. 2017 Dec 15;199(12):4066-4077. doi: 10.4049/jimmunol.1701211. Epub 2017 Nov 10.

23.

Endonuclease Regnase-1/Monocyte chemotactic protein-1-induced protein-1 (MCPIP1) in controlling immune responses and beyond.

Takeuchi O.

Wiley Interdiscip Rev RNA. 2018 Jan;9(1). doi: 10.1002/wrna.1449. Epub 2017 Sep 20. Review.

PMID:
28929622
24.

Regnase-1 Maintains Iron Homeostasis via the Degradation of Transferrin Receptor 1 and Prolyl-Hydroxylase-Domain-Containing Protein 3 mRNAs.

Yoshinaga M, Nakatsuka Y, Vandenbon A, Ori D, Uehata T, Tsujimura T, Suzuki Y, Mino T, Takeuchi O.

Cell Rep. 2017 May 23;19(8):1614-1630. doi: 10.1016/j.celrep.2017.05.009.

25.

Regnase-1 Is an Endoribonuclease Essential for the Maintenance of Immune Homeostasis.

Uehata T, Takeuchi O.

J Interferon Cytokine Res. 2017 May;37(5):220-229. doi: 10.1089/jir.2017.0001. Review.

PMID:
28475459
26.

Translational control of mRNAs by 3'-Untranslated region binding proteins.

Yamashita A, Takeuchi O.

BMB Rep. 2017 Apr;50(4):194-200. Review.

27.

Mitochondrial damage elicits a TCDD-inducible poly(ADP-ribose) polymerase-mediated antiviral response.

Kozaki T, Komano J, Kanbayashi D, Takahama M, Misawa T, Satoh T, Takeuchi O, Kawai T, Shimizu S, Matsuura Y, Akira S, Saitoh T.

Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2681-2686. doi: 10.1073/pnas.1621508114. Epub 2017 Feb 17.

28.

Evaluation of Suppressive Effects of Tranilast on the Invasion/Metastasis Mechanism in a Murine Pancreatic Cancer Cell Line.

Kaneda M, Obara H, Suzuki K, Takeuchi O, Takizawa A, Osaku M, Matsubara H, Kitagawa Y.

Pancreas. 2017 Apr;46(4):567-574. doi: 10.1097/MPA.0000000000000779.

PMID:
28196028
29.

Pathogen recognition and Toll-like receptor targeted therapeutics in innate immune cells.

Tartey S, Takeuchi O.

Int Rev Immunol. 2017 Mar 4;36(2):57-73. doi: 10.1080/08830185.2016.1261318. Epub 2017 Jan 6. Review.

PMID:
28060562
30.

Revealing the Conformational Dynamics in a Single-Molecule Junction by Site- and Angle-Resolved Dynamic Probe Method.

Yoshida S, Taninaka A, Sugita Y, Katayama T, Takeuchi O, Shigekawa H.

ACS Nano. 2016 Dec 27;10(12):11211-11218. doi: 10.1021/acsnano.6b06278. Epub 2016 Dec 2.

PMID:
28024353
31.

Genetic polymorphisms of enzyme proteins and transporters related to methotrexate response and pharmacokinetics in a Japanese population.

Hashiguchi M, Shimizu M, Hakamata J, Tsuru T, Tanaka T, Suzaki M, Miyawaki K, Chiyoda T, Takeuchi O, Hiratsuka J, Irie S, Maruyama J, Mochizuki M.

J Pharm Health Care Sci. 2016 Dec 9;2:35. eCollection 2016.

32.

Pillars Article: Cutting Edge: Toll-Like Receptor 4 (TLR4)-Deficient Mice Are Hyporesponsive to Lipopolysaccharide: Evidence for TLR4 as the Lps Gene Product. J. Immunol. 1999. 162: 3749-3752.

Hoshino K, Takeuchi O, Kawai T, Sanjo H, Ogawa T, Takeda Y, Takeda K, Akira S.

J Immunol. 2016 Oct 1;197(7):2563-6. No abstract available.

33.

Modulation of electrical potential and conductivity in an atomic-layer semiconductor heterojunction.

Kobayashi Y, Yoshida S, Sakurada R, Takashima K, Yamamoto T, Saito T, Konabe S, Taniguchi T, Watanabe K, Maniwa Y, Takeuchi O, Shigekawa H, Miyata Y.

Sci Rep. 2016 Aug 12;6:31223. doi: 10.1038/srep31223.

34.
35.

[Post-transcriptional regulation of inflammatory mRNA by Regnase-1 and Roquin].

Mino T, Takeuchi O.

Nihon Yakurigaku Zasshi. 2016 Jun;147(6):351-6. doi: 10.1254/fpj.147.351. Japanese. No abstract available.

PMID:
27301309
36.

Attractive interaction between Mn atoms on the GaAs(110) surface observed by scanning tunneling microscopy.

Taninaka A, Yoshida S, Kanazawa K, Hayaki E, Takeuchi O, Shigekawa H.

Nanoscale. 2016 Jun 16;8(24):12118-22. doi: 10.1039/c6nr02190e.

PMID:
27263630
37.

Sex Differences in mRNA Expression of Reduced Folate Carrier-1, Folypolyformyl Glutamate Synthase, and γ-Glutamyl Hydrolase in a Healthy Japanese Population.

Hashiguchi M, Tanaka T, Shimizu M, Tsuru T, Chiyoda T, Miyawaki K, Irie S, Takeuchi O, Hakamata J, Mochizuki M.

J Clin Pharmacol. 2016 Dec;56(12):1563-1569. doi: 10.1002/jcph.760. Epub 2016 May 18.

PMID:
27146084
38.

Arid5a regulates naive CD4+ T cell fate through selective stabilization of Stat3 mRNA.

Masuda K, Ripley B, Nyati KK, Dubey PK, Zaman MM, Hanieh H, Higa M, Yamashita K, Standley DM, Mashima T, Katahira M, Okamoto T, Matsuura Y, Takeuchi O, Kishimoto T.

J Exp Med. 2016 Apr 4;213(4):605-19. doi: 10.1084/jem.20151289. Epub 2016 Mar 28.

39.

Inhibition of IL-1R1/MyD88 signalling promotes mesenchymal stem cell-driven tissue regeneration.

Martino MM, Maruyama K, Kuhn GA, Satoh T, Takeuchi O, Müller R, Akira S.

Nat Commun. 2016 Mar 22;7:11051. doi: 10.1038/ncomms11051.

40.

Structural basis for the regulation of enzymatic activity of Regnase-1 by domain-domain interactions.

Yokogawa M, Tsushima T, Noda NN, Kumeta H, Enokizono Y, Yamashita K, Standley DM, Takeuchi O, Akira S, Inagaki F.

Sci Rep. 2016 Mar 1;6:22324. doi: 10.1038/srep22324.

41.

Flesh-eating Streptococcus pyogenes triggers the expression of receptor activator of nuclear factor-κB ligand.

Matsui H, Nakatani Y, Yoshida H, Takizawa A, Takeuchi O, Øverby A, Takahashi T, Murayama SY, Matsuo K.

Cell Microbiol. 2016 Oct;18(10):1390-404. doi: 10.1111/cmi.12581. Epub 2016 Mar 22.

PMID:
26894505
42.

Akirin2-Mediated Transcriptional Control by Recruiting SWI/SNF Complex in B Cells.

Tartey S, Takeuchi O.

Crit Rev Immunol. 2016;36(5):395-406. doi: 10.1615/CritRevImmunol.2017019629. Review.

PMID:
28605346
43.

Microscopic basis for the band engineering of Mo1-xWxS2-based heterojunction.

Yoshida S, Kobayashi Y, Sakurada R, Mori S, Miyata Y, Mogi H, Koyama T, Takeuchi O, Shigekawa H.

Sci Rep. 2015 Oct 7;5:14808. doi: 10.1038/srep14808.

44.

Mechanically activated switching of Si-based single-molecule junction as imaged with three-dimensional dynamic probe.

Nakamura M, Yoshida S, Katayama T, Taninaka A, Mera Y, Okada S, Takeuchi O, Shigekawa H.

Nat Commun. 2015 Oct 6;6:8465. doi: 10.1038/ncomms9465.

45.

Chromatin Remodeling and Transcriptional Control in Innate Immunity: Emergence of Akirin2 as a Novel Player.

Tartey S, Takeuchi O.

Biomolecules. 2015 Jul 22;5(3):1618-33. doi: 10.3390/biom5031618. Review.

46.

Regnase-1 and Roquin regulate inflammatory mRNAs.

Mino T, Takeuchi O.

Oncotarget. 2015 Jul 20;6(20):17869-70. No abstract available.

47.

Essential Function for the Nuclear Protein Akirin2 in B Cell Activation and Humoral Immune Responses.

Tartey S, Matsushita K, Imamura T, Wakabayashi A, Ori D, Mino T, Takeuchi O.

J Immunol. 2015 Jul 15;195(2):519-27. doi: 10.4049/jimmunol.1500373. Epub 2015 Jun 3.

48.

Regnase-1 and Roquin Regulate a Common Element in Inflammatory mRNAs by Spatiotemporally Distinct Mechanisms.

Mino T, Murakawa Y, Fukao A, Vandenbon A, Wessels HH, Ori D, Uehata T, Tartey S, Akira S, Suzuki Y, Vinuesa CG, Ohler U, Standley DM, Landthaler M, Fujiwara T, Takeuchi O.

Cell. 2015 May 21;161(5):1058-1073. doi: 10.1016/j.cell.2015.04.029.

49.

A Lipopolysaccharide from Pantoea Agglomerans Is a Promising Adjuvant for Sublingual Vaccines to Induce Systemic and Mucosal Immune Responses in Mice via TLR4 Pathway.

Fukasaka M, Asari D, Kiyotoh E, Okazaki A, Gomi Y, Tanimoto T, Takeuchi O, Akira S, Hori M.

PLoS One. 2015 May 15;10(5):e0126849. doi: 10.1371/journal.pone.0126849. eCollection 2015.

50.

HuR keeps interferon-β mRNA stable.

Takeuchi O.

Eur J Immunol. 2015 May;45(5):1296-9. doi: 10.1002/eji.201545616.

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