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Items: 1 to 50 of 55

1.

Overexpression of miR‑221 and miR‑222 in the cancer stroma is associated with malignant potential in colorectal cancer.

Iida M, Hazama S, Tsunedomi R, Tanaka H, Takenouchi H, Kanekiyo S, Tokumitsu Y, Tomochika S, Tokuhisa Y, Sakamoto K, Suzuki N, Takeda S, Ueno T, Yamamoto S, Yoshino S, Fujita K, Kuroda M, Nagano H.

Oncol Rep. 2018 Jul 13. doi: 10.3892/or.2018.6575. [Epub ahead of print]

PMID:
30015977
2.

Hedgehog Signals Mediate Anti-Cancer Drug Resistance in Three-Dimensional Primary Colorectal Cancer Organoid Culture.

Usui T, Sakurai M, Umata K, Elbadawy M, Ohama T, Yamawaki H, Hazama S, Takenouchi H, Nakajima M, Tsunedomi R, Suzuki N, Nagano H, Sato K, Kaneda M, Sasaki K.

Int J Mol Sci. 2018 Apr 6;19(4). pii: E1098. doi: 10.3390/ijms19041098.

3.

IgG response to MHC class I epitope peptides is a quantitative predictive biomarker in the early course of treatment of colorectal cancer using therapeutic peptides.

Kanekiyo S, Hazama S, Takenouchi H, Nakajima M, Shindo Y, Matsui H, Tokumitsu Y, Tomochika S, Tsunedomi R, Tokuhisa Y, Iida M, Sakamoto K, Suzuki N, Takeda S, Yamamoto S, Yoshino S, Okuno K, Udaka K, Kawakami Y, Matsueda S, Ito K, Nagano H.

Oncol Rep. 2018 May;39(5):2385-2392. doi: 10.3892/or.2018.6288. Epub 2018 Mar 1.

PMID:
29498403
4.

Stemness Is Enhanced in Gastric Cancer by a SET/PP2A/E2F1 Axis.

Enjoji S, Yabe R, Tsuji S, Yoshimura K, Kawasaki H, Sakurai M, Sakai Y, Takenouchi H, Yoshino S, Hazama S, Nagano H, Oshima H, Oshima M, Vitek MP, Matsuura T, Hippo Y, Usui T, Ohama T, Sato K.

Mol Cancer Res. 2018 Mar;16(3):554-563. doi: 10.1158/1541-7786.MCR-17-0393. Epub 2018 Jan 12.

PMID:
29330298
5.

miR-125b-1 and miR-378a are predictive biomarkers for the efficacy of vaccine treatment against colorectal cancer.

Tanaka H, Hazama S, Iida M, Tsunedomi R, Takenouchi H, Nakajima M, Tokumitsu Y, Kanekiyo S, Shindo Y, Tomochika S, Tokuhisa Y, Sakamoto K, Suzuki N, Takeda S, Yamamoto S, Yoshino S, Ueno T, Hamamoto Y, Fujita Y, Tanaka H, Tahara K, Shimizu R, Okuno K, Fujita K, Kuroda M, Nakamura Y, Nagano H.

Cancer Sci. 2017 Nov;108(11):2229-2238. doi: 10.1111/cas.13390. Epub 2017 Sep 22.

6.

miR-196b, miR-378a and miR-486 are predictive biomarkers for the efficacy of vaccine treatment in colorectal cancer.

Shindo Y, Hazama S, Nakamura Y, Inoue Y, Kanekiyo S, Suzuki N, Takenouchi H, Tsunedomi R, Nakajima M, Ueno T, Takeda S, Yoshino S, Okuno K, Fujita Y, Hamamoto Y, Kawakami Y, Oka M, Nagano H.

Oncol Lett. 2017 Aug;14(2):1355-1362. doi: 10.3892/ol.2017.6303. Epub 2017 Jun 2.

7.

Predictive biomarkers for the efficacy of peptide vaccine treatment: based on the results of a phase II study on advanced pancreatic cancer.

Shindo Y, Hazama S, Suzuki N, Iguchi H, Uesugi K, Tanaka H, Aruga A, Hatori T, Ishizaki H, Umeda Y, Fujiwara T, Ikemoto T, Shimada M, Yoshimatsu K, Takenouchi H, Matsui H, Kanekiyo S, Iida M, Koki Y, Arima H, Furukawa H, Ueno T, Yoshino S, Fujita T, Kawakami Y, Nakamura Y, Oka M, Nagano H.

J Exp Clin Cancer Res. 2017 Feb 28;36(1):36. doi: 10.1186/s13046-017-0509-1.

8.

Multiple optical carrier generation using frequency mixing in damage resistant multiple QPM device.

Nakamura K, Channa H, Asobe M, Umeki T, Takenouchi H.

Opt Express. 2017 Feb 20;25(4):3639-3645. doi: 10.1364/OE.25.003639.

PMID:
28241576
9.

Establishment of a Novel Model for Anticancer Drug Resistance in Three-Dimensional Primary Culture of Tumor Microenvironment.

Usui T, Sakurai M, Enjoji S, Kawasaki H, Umata K, Ohama T, Fujiwara N, Yabe R, Tsuji S, Yamawaki H, Hazama S, Takenouchi H, Nakajima M, Tsunedomi R, Suzuki N, Nagano H, Sato K.

Stem Cells Int. 2016;2016:7053872. doi: 10.1155/2016/7053872. Epub 2016 Dec 29.

10.

MicroRNA-6826 and -6875 in plasma are valuable non‑invasive biomarkers that predict the efficacy of vaccine treatment against metastatic colorectal cancer.

Kijima T, Hazama S, Tsunedomi R, Tanaka H, Takenouchi H, Kanekiyo S, Inoue Y, Nakashima M, Iida M, Sakamoto K, Suzuki N, Takeda S, Ueno T, Yamamoto S, Yoshino S, Okuno K, Nagano H.

Oncol Rep. 2017 Jan;37(1):23-30. doi: 10.3892/or.2016.5267. Epub 2016 Nov 22.

11.

A coherent Ising machine for 2000-node optimization problems.

Inagaki T, Haribara Y, Igarashi K, Sonobe T, Tamate S, Honjo T, Marandi A, McMahon PL, Umeki T, Enbutsu K, Tadanaga O, Takenouchi H, Aihara K, Kawarabayashi KI, Inoue K, Utsunomiya S, Takesue H.

Science. 2016 Nov 4;354(6312):603-606. Epub 2016 Oct 20.

PMID:
27811271
12.

Phase II clinical trial of peptide cocktail therapy for patients with advanced pancreatic cancer: VENUS-PC study.

Suzuki N, Hazama S, Iguchi H, Uesugi K, Tanaka H, Hirakawa K, Aruga A, Hatori T, Ishizaki H, Umeda Y, Fujiwara T, Ikemoto T, Shimada M, Yoshimatsu K, Shimizu R, Hayashi H, Sakata K, Takenouchi H, Matsui H, Shindo Y, Iida M, Koki Y, Arima H, Furukawa H, Ueno T, Yoshino S, Nakamura Y, Oka M, Nagano H.

Cancer Sci. 2017 Jan;108(1):73-80. doi: 10.1111/cas.13113. Epub 2016 Dec 19.

13.

Prediction of the efficacy of immunotherapy by measuring the integrity of cell-free DNA in plasma in colorectal cancer.

Kitahara M, Hazama S, Tsunedomi R, Takenouchi H, Kanekiyo S, Inoue Y, Nakajima M, Tomochika S, Tokuhisa Y, Iida M, Sakamoto K, Suzuki N, Takeda S, Ueno T, Yamamoto S, Yoshino S, Nagano H.

Cancer Sci. 2016 Dec;107(12):1825-1829. doi: 10.1111/cas.13085. Epub 2016 Dec 18.

14.

Investigation of SO3 absorption line for in situ gas detection inside combustion plants using a 4-μm-band laser source.

Tokura A, Tadanaga O, Nishimiya T, Muta K, Kamiyama N, Yonemura M, Fujii S, Tsumura Y, Abe M, Takenouchi H, Kenmotsu K, Sakai Y.

Appl Opt. 2016 Sep 1;55(25):6887-92. doi: 10.1364/AO.55.006887.

PMID:
27607263
15.

Simultaneous nonlinearity mitigation in 92 × 180-Gbit/s PDM-16QAM transmission over 3840 km using PPLN-based guard-band-less optical phase conjugation.

Umeki T, Kazama T, Sano A, Shibahara K, Suzuki K, Abe M, Takenouchi H, Miyamoto Y.

Opt Express. 2016 Jul 25;24(15):16945-51. doi: 10.1364/OE.24.016945.

PMID:
27464146
16.

Characterization of the T cell repertoire by deep T cell receptor sequencing in tissues and blood from patients with advanced colorectal cancer.

Tamura K, Hazama S, Yamaguchi R, Imoto S, Takenouchi H, Inoue Y, Kanekiyo S, Shindo Y, Miyano S, Nakamura Y, Kiyotani K.

Oncol Lett. 2016 Jun;11(6):3643-3649. Epub 2016 Apr 19.

17.

Rapid spectrum measurement at 3  μm over 100  nm wavelength range using mid-infrared difference frequency generation source.

Abe M, Nishida Y, Tadanaga O, Tokura A, Takenouchi H.

Opt Lett. 2016 Apr 1;41(7):1380-3. doi: 10.1364/OL.41.001380.

PMID:
27192241
18.

Dual wavelength 3.2-μm source for isotope ratio measurements of (13)CH(4)/(12)CH(4).

Abe M, Kusanagi S, Nishida Y, Tadanaga O, Takenouchi H, Sasada H.

Opt Express. 2015 Aug 24;23(17):21786-97. doi: 10.1364/OE.23.021786.

PMID:
26368155
19.

Integrated quasi-phase-matched second-harmonic generator and electro-optic phase modulator for low-noise phase-sensitive amplification.

Enbutsu K, Umeki T, Tadanaga O, Asobe M, Takenouchi H.

Opt Lett. 2015 Jul 15;40(14):3336-9. doi: 10.1364/OL.40.003336.

PMID:
26176463
20.

In-line phase-sensitive amplification of QPSK signal using multiple quasi-phase matched LiNbO₃ waveguide.

Asobe M, Umeki T, Takenouchi H, Miyamoto Y.

Opt Express. 2014 Nov 3;22(22):26642-50. doi: 10.1364/OE.22.026642.

PMID:
25401814
21.

Predictive biomarkers for the outcome of vaccination of five therapeutic epitope peptides for colorectal cancer.

Hazama S, Takenouchi H, Tsunedomi R, Iida M, Suzuki N, Iizuka N, Inoue Y, Sakamoto K, Nakao M, Shindo Y, Kanekiyo S, Tokumitsu Y, Yoshimura K, Maeda N, Maeda K, Maeda Y, Matsui H, Yoshino S, Nakamura Y, Fujita Y, Hamamoto Y, Okamoto M, Fujita T, Kawakami Y, Oka M.

Anticancer Res. 2014 Aug;34(8):4201-5.

PMID:
25075047
22.

Properties of power dependence on low-crosstalk waveband conversion with an apodized multiperiod-QPM LiNbO₃ device.

Tomita I, Umeki T, Tadanaga O, Song H, Asobe M, Takenouchi H.

Opt Express. 2014 Jun 16;22(12):15232-44. doi: 10.1364/OE.22.015232.

PMID:
24977614
23.

A healing period increases mini-implant stability in growing rats.

Yano S, Motoyoshi M, Inaba M, Yano S, Takenouchi H, Son S, Arai Y, Shimizu N.

J Oral Sci. 2014 Jun;56(2):113-8.

24.

A phase ΙI study of five peptides combination with oxaliplatin-based chemotherapy as a first-line therapy for advanced colorectal cancer (FXV study).

Hazama S, Nakamura Y, Tanaka H, Hirakawa K, Tahara K, Shimizu R, Ozasa H, Etoh R, Sugiura F, Okuno K, Furuya T, Nishimura T, Sakata K, Yoshimatsu K, Takenouchi H, Tsunedomi R, Inoue Y, Kanekiyo S, Shindo Y, Suzuki N, Yoshino S, Shinozaki H, Kamiya A, Furukawa H, Yamanaka T, Fujita T, Kawakami Y, Oka M.

J Transl Med. 2014 Apr 30;12:108. doi: 10.1186/1479-5876-12-108.

25.

First demonstration of high-order QAM signal amplification in PPLN-based phase sensitive amplifier.

Umeki T, Tadanaga O, Asobe M, Miyamoto Y, Takenouchi H.

Opt Express. 2014 Feb 10;22(3):2473-82. doi: 10.1364/OE.22.002473.

PMID:
24663539
26.

A phase I study of combination vaccine treatment of five therapeutic epitope-peptides for metastatic colorectal cancer; safety, immunological response, and clinical outcome.

Hazama S, Nakamura Y, Takenouchi H, Suzuki N, Tsunedomi R, Inoue Y, Tokuhisa Y, Iizuka N, Yoshino S, Takeda K, Shinozaki H, Kamiya A, Furukawa H, Oka M.

J Transl Med. 2014 Mar 10;12:63. doi: 10.1186/1479-5876-12-63.

27.

Longitudinal quantitative evaluation of the mid-palatal suture after rapid expansion using in vivo micro-CT.

Takenouchi H, Mayahara K, Arai Y, Karasawa Y, Shimizu N.

Arch Oral Biol. 2014 Apr;59(4):414-23. doi: 10.1016/j.archoralbio.2014.01.010. Epub 2014 Feb 2.

PMID:
24534134
28.

Multi-span transmission using phase and amplitude regeneration in PPLN-based PSA.

Umeki T, Asobe M, Takara H, Miyamoto Y, Takenouchi H.

Opt Express. 2013 Jul 29;21(15):18170-7. doi: 10.1364/OE.21.018170.

PMID:
23938687
29.

Real-time N2O gas detection system for agricultural production using a 4.6-µm-band laser source based on a periodically poled LiNbO3 ridge waveguide.

Tokura A, Asobe M, Enbutsu K, Yoshihara T, Hashida SN, Takenouchi H.

Sensors (Basel). 2013 Aug 5;13(8):9999-10013. doi: 10.3390/s130809999.

30.

In-line phase sensitive amplifier based on PPLN waveguides.

Umeki T, Asobe M, Takenouchi H.

Opt Express. 2013 May 20;21(10):12077-84. doi: 10.1364/OE.21.012077.

PMID:
23736428
31.

Osteoblasts stimulate osteoclastogenesis via RANKL expression more strongly than periodontal ligament cells do in response to PGE(2).

Mayahara K, Yamaguchi A, Takenouchi H, Kariya T, Taguchi H, Shimizu N.

Arch Oral Biol. 2012 Oct;57(10):1377-84. doi: 10.1016/j.archoralbio.2012.07.009. Epub 2012 Aug 9.

PMID:
22884709
32.

Hybrid optoelectronic buffer using CMOS memory and optical interfaces for 10-Gbit/s asynchronous variable-length optical packets.

Nakahara T, Takenouchi H, Urata R, Yamazaki H, Takahashi R.

Opt Express. 2010 Sep 27;18(20):20565-71. doi: 10.1364/OE.18.020565.

PMID:
20940951
33.

4x4 optical packet switching of asynchronous burst optical packets with a prototype, 4x4 label processing and switching sub-system.

Urata R, Nakahara T, Takenouchi H, Segawa T, Ishikawa H, Ohki A, Sugiyama H, Nishihara S, Takahashi R.

Opt Express. 2010 Jul 19;18(15):15283-8. doi: 10.1364/OE.18.015283.

PMID:
20720905
34.

Defective human T-lymphotropic virus type 1 provirus in asymptomatic carriers.

Takenouchi H, Umeki K, Sasaki D, Yamamoto I, Nomura H, Takajo I, Ueno S, Umekita K, Kamihira S, Morishita K, Okayama A.

Int J Cancer. 2011 Mar 15;128(6):1335-43. doi: 10.1002/ijc.25450.

35.

Human osteoblasts support hematopoietic cell development in vitro.

Shiozawa Y, Takenouchi H, Taguchi T, Saito M, Katagiri YU, Okita H, Shimizu T, Yamashiro Y, Fujimoto J, Kiyokawa N.

Acta Haematol. 2008;120(3):134-45. doi: 10.1159/000178144. Epub 2008 Nov 28.

PMID:
19039204
36.

Interleukin-7 contributes to human pro-B-cell development in a mouse stromal cell-dependent culture system.

Taguchi T, Takenouchi H, Shiozawa Y, Matsui J, Kitamura N, Miyagawa Y, Katagiri YU, Takahashi T, Okita H, Fujimoto J, Kiyokawa N.

Exp Hematol. 2007 Sep;35(9):1398-407. Epub 2007 Jul 25.

PMID:
17656007
37.

Characterization of monocyte-macrophage-lineage cells induced from CD34+ bone marrow cells in vitro.

Suzuki K, Kiyokawa N, Taguchi T, Takenouchi H, Saito M, Shimizu T, Okita H, Fujimoto J.

Int J Hematol. 2007 Jun;85(5):384-9.

PMID:
17562612
38.

Src homology 2 (SH2)-containing 5'-inositol phosphatase localizes to podosomes, and the SH2 domain is implicated in the attenuation of bone resorption in osteoclasts.

Yogo K, Mizutamari M, Mishima K, Takenouchi H, Ishida-Kitagawa N, Sasaki T, Takeya T.

Endocrinology. 2006 Jul;147(7):3307-17. Epub 2006 Apr 6.

PMID:
16601135
39.

Involvement of insulin-like growth factor-I and insulin-like growth factor binding proteins in pro-B-cell development.

Taguchi T, Takenouchi H, Matsui J, Tang WR, Itagaki M, Shiozawa Y, Suzuki K, Sakaguchi S, Ktagiri YU, Takahashi T, Okita H, Fujimoto J, Kiyokawa N.

Exp Hematol. 2006 Apr;34(4):508-18.

PMID:
16569597
40.

Laminin binding protein, 34/67 laminin receptor, carries stage-specific embryonic antigen-4 epitope defined by monoclonal antibody Raft.2.

Katagiri YU, Kiyokawa N, Nakamura K, Takenouchi H, Taguchi T, Okita H, Umezawa A, Fujimoto J.

Biochem Biophys Res Commun. 2005 Jul 15;332(4):1004-11.

PMID:
15922307
41.

Dietary bioflavonoids induce apoptosis in human leukemia cells.

Matsui J, Kiyokawa N, Takenouchi H, Taguchi T, Suzuki K, Shiozawa Y, Saito M, Tang WR, Katagiri YU, Okita H, Fujimoto J.

Leuk Res. 2005 May;29(5):573-81. Epub 2005 Jan 19.

PMID:
15755510
42.

Characterization of new monoclonal antibodies against porcine lymphocytes: molecular characterization of clone 7G3, an antibody reactive with the constant region of the T-cell receptor delta-chains.

Tang WR, Shioya N, Eguchi T, Ebata T, Matsui J, Takenouchi H, Honma D, Yasue H, Takagaki Y, Enosawa S, Itagaki M, Taguchi T, Kiyokawa N, Amemiya H, Fujimoto J.

Vet Immunol Immunopathol. 2005 Jan 10;103(1-2):113-27.

PMID:
15626467
43.

Development of novel monoclonal antibody 4G8 against swine leukocyte antigen class I alpha chain.

Tang WR, Kiyokawa N, Eguchi T, Matsui J, Takenouchi H, Honma D, Yasue H, Enosawa S, Mimori K, Itagaki M, Taguchi T, Katagiri YU, Okita H, Amemiya H, Fujimoto J.

Hybrid Hybridomics. 2004 Jun;23(3):187-91.

PMID:
15312310
44.

Shiga toxin binding to globotriaosyl ceramide induces intracellular signals that mediate cytoskeleton remodeling in human renal carcinoma-derived cells.

Takenouchi H, Kiyokawa N, Taguchi T, Matsui J, Katagiri YU, Okita H, Okuda K, Fujimoto J.

J Cell Sci. 2004 Aug 1;117(Pt 17):3911-22. Epub 2004 Jul 20.

45.

Characterization of a shiga-toxin 1-resistant stock of vero cells.

Sekino T, Kiyokawa N, Taguchi T, Takenouchi H, Matsui J, Tang WR, Suzuki T, Nakajima H, Saito M, Ohmi K, Katagiri YU, Okita H, Nakao H, Takeda T, Fujimoto J.

Microbiol Immunol. 2004;48(5):377-87.

46.

Diagnostic importance of CD179a/b as markers of precursor B-cell lymphoblastic lymphoma.

Kiyokawa N, Sekino T, Matsui T, Takenouchi H, Mimori K, Tang WR, Matsui J, Taguchi T, Katagiri YU, Okita H, Matsuo Y, Karasuyama H, Fujimoto J.

Mod Pathol. 2004 Apr;17(4):423-9.

47.
48.

[Measles vaccination for children with allergic diseases].

Hirokado M, Takamasu T, Takenouchi H, Kotoyori T, Kurihara K.

Arerugi. 2002 Aug;51(8):622-9. Japanese.

PMID:
12368566
49.

Rum1, an inhibitor of cyclin-dependent kinase in fission yeast, is negatively regulated by mitogen-activated protein kinase-mediated phosphorylation at Ser and Thr residues.

Matsuoka K, Kiyokawa N, Taguchi T, Matsui J, Suzuki T, Mimori K, Nakajima H, Takenouchi H, Weiran T, Katagiri YU, Fujimoto J.

Eur J Biochem. 2002 Jul;269(14):3511-21.

50.

An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12.

Morishima N, Nakanishi K, Takenouchi H, Shibata T, Yasuhiko Y.

J Biol Chem. 2002 Sep 13;277(37):34287-94. Epub 2002 Jul 3.

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