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Items: 1 to 50 of 165

1.

Propofol induces a metabolic switch to glycolysis and cell death in a mitochondrial electron transport chain-dependent manner.

Sumi C, Okamoto A, Tanaka H, Nishi K, Kusunoki M, Shoji T, Uba T, Matsuo Y, Adachi T, Hayashi JI, Takenaga K, Hirota K.

PLoS One. 2018 Feb 15;13(2):e0192796. doi: 10.1371/journal.pone.0192796. eCollection 2018.

2.

Role of the IL-33/ST2L axis in colorectal cancer progression.

Akimoto M, Takenaga K.

Cell Immunol. 2018 Jan 9. pii: S0008-8749(17)30241-1. doi: 10.1016/j.cellimm.2017.12.014. [Epub ahead of print]

PMID:
29329638
3.

Association of predicted pathogenic mutations in mitochondrial ND genes with distant metastasis in NSCLC and colon cancer.

Koshikawa N, Akimoto M, Hayashi JI, Nagase H, Takenaga K.

Sci Rep. 2017 Nov 14;7(1):15535. doi: 10.1038/s41598-017-15592-2.

4.

Cytoplasmic transfer of heritable elements other than mtDNA from SAMP1 mice into mouse tumor cells suppresses their ability to form tumors in C57BL6 mice.

Shimizu A, Tani H, Takibuchi G, Ishikawa K, Sakurazawa R, Inoue T, Hashimoto T, Nakada K, Takenaga K, Hayashi JI.

Biochem Biophys Res Commun. 2017 Nov 4;493(1):252-257. doi: 10.1016/j.bbrc.2017.09.035. Epub 2017 Sep 9.

5.

HIF-1-mediated suppression of mitochondria electron transport chain function confers resistance to lidocaine-induced cell death.

Okamoto A, Sumi C, Tanaka H, Kusunoki M, Iwai T, Nishi K, Matsuo Y, Harada H, Takenaga K, Bono H, Hirota K.

Sci Rep. 2017 Jun 19;7(1):3816. doi: 10.1038/s41598-017-03980-7.

6.

HIF-2α dictates the susceptibility of pancreatic cancer cells to TRAIL by regulating survivin expression.

Harashima N, Takenaga K, Akimoto M, Harada M.

Oncotarget. 2017 Jun 27;8(26):42887-42900. doi: 10.18632/oncotarget.17157.

7.

Optimal design of 4LP-mode multicore fibers for high spatial multiplicity.

Tobita Y, Fujisawa T, Sakamoto T, Matsui T, Saitoh S, Takenaga K, Aikawa K, Aozasa S, Nakajima K, Saitoh K.

Opt Express. 2017 Mar 6;25(5):5697-5709. doi: 10.1364/OE.25.005697.

PMID:
28380826
8.

Soluble IL-33 receptor sST2 inhibits colorectal cancer malignant growth by modifying the tumour microenvironment.

Akimoto M, Maruyama R, Takamaru H, Ochiya T, Takenaga K.

Nat Commun. 2016 Nov 24;7:13589. doi: 10.1038/ncomms13589.

9.

The antioxidant N-acetyl cysteine suppresses lidocaine-induced intracellular reactive oxygen species production and cell death in neuronal SH-SY5Y cells.

Okamoto A, Tanaka M, Sumi C, Oku K, Kusunoki M, Nishi K, Matsuo Y, Takenaga K, Shingu K, Hirota K.

BMC Anesthesiol. 2016 Oct 24;16(1):104.

10.

Interleukin-33 enhances programmed oncosis of ST2L-positive low-metastatic cells in the tumour microenvironment of lung cancer.

Akimoto M, Hayashi JI, Nakae S, Saito H, Takenaga K.

Cell Death Dis. 2016 Jan 21;7:e2057. doi: 10.1038/cddis.2015.418.

11.

Mode-selective optical packet switching in mode-division multiplexing networks.

Diamantopoulos NP, Hayashi M, Yoshida Y, Maruta A, Maruyama R, Kuwaki N, Takenaga K, Uemura H, Matsuo S, Kitayama K.

Opt Express. 2015 Sep 7;23(18):23660-6. doi: 10.1364/OE.23.023660.

PMID:
26368463
12.

Heterogeneous trench-assisted few-mode multi-core fiber with graded-index profile and square-lattice layout for low differential mode delay.

Tu J, Saitoh K, Amma Y, Takenaga K, Matsuo S.

Opt Express. 2015 Jul 13;23(14):17783-92. doi: 10.1364/OE.23.017783.

PMID:
26191840
13.

Efficient inhibition of tumor angiogenesis and growth by a synthetic peptide blocking S100A4-methionine aminopeptidase 2 interaction.

Ochiya T, Takenaga K, Asagiri M, Nakano K, Satoh H, Watanabe T, Imajoh-Ohmi S, Endo H.

Mol Ther Methods Clin Dev. 2015 Apr 1;2:15008. doi: 10.1038/mtm.2015.8. eCollection 2015.

14.

Anticancer Effect of Ginger Extract against Pancreatic Cancer Cells Mainly through Reactive Oxygen Species-Mediated Autotic Cell Death.

Akimoto M, Iizuka M, Kanematsu R, Yoshida M, Takenaga K.

PLoS One. 2015 May 11;10(5):e0126605. doi: 10.1371/journal.pone.0126605. eCollection 2015.

15.

Heterogeneous trench-assisted few-mode multi-core fiber with low differential mode delay.

Tu J, Saitoh K, Takenaga K, Matsuo S.

Opt Express. 2014 Feb 24;22(4):4329-41. doi: 10.1364/OE.22.004329.

PMID:
24663756
16.

Transmitochondrial mice as models for primary prevention of diseases caused by mutation in the tRNA(Lys) gene.

Shimizu A, Mito T, Hayashi C, Ogasawara E, Koba R, Negishi I, Takenaga K, Nakada K, Hayashi J.

Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3104-9. doi: 10.1073/pnas.1318109111. Epub 2014 Feb 7.

17.

Specific mtDNA mutations in mouse carcinoma cells suppress their tumor formation via activation of the host innate immune system.

Imanishi H, Takibuchi G, Kobayashi T, Ishikawa K, Nakada K, Mori M, Kikkawa Y, Takenaga K, Toyama-Sorimachi N, Hayashi J.

PLoS One. 2013 Sep 30;8(9):e75981. doi: 10.1371/journal.pone.0075981. eCollection 2013.

18.

409-Tb/s + 409-Tb/s crosstalk suppressed bidirectional MCF transmission over 450 km using propagation-direction interleaving.

Sano A, Takara H, Kobayashi T, Kawakami H, Kishikawa H, Nakagawa T, Miyamoto Y, Abe Y, Ono H, Shikama K, Nagatani M, Mori T, Sasaki Y, Ishida I, Takenaga K, Matsuo S, Saitoh K, Koshiba M, Yamada M, Masuda H, Morioka T.

Opt Express. 2013 Jul 15;21(14):16777-83. doi: 10.1364/OE.21.016777.

PMID:
23938529
19.

Polymorphic mutations in mouse mitochondrial DNA regulate a tumor phenotype.

Takibuchi G, Imanishi H, Morimoto M, Ishikawa K, Nakada K, Toyama-Sorimachi N, Kikkawa Y, Takenaga K, Hayashi J.

Mitochondrion. 2013 Nov;13(6):881-7. doi: 10.1016/j.mito.2013.07.117. Epub 2013 Aug 6.

PMID:
23932994
20.

Silencing of S100A4, a metastasis-associated protein, in endothelial cells inhibits tumor angiogenesis and growth.

Ochiya T, Takenaga K, Endo H.

Angiogenesis. 2014 Jan;17(1):17-26. doi: 10.1007/s10456-013-9372-7. Epub 2013 Aug 9.

21.

Antitumor effect of Japanese apricot extract (MK615) on human cancer cells in vitro and in vivo through a reactive oxygen species-dependent mechanism.

Hattori M, Kawakami K, Akimoto M, Takenaga K, Suzumiya J, Honma Y.

Tumori. 2013 Mar-Apr;99(2):239-48. doi: 10.1700/1283.14199.

PMID:
23748821
22.

12-core fiber with one ring structure for extremely large capacity transmission.

Matsuo S, Sasaki Y, Akamatsu T, Ishida I, Takenaga K, Okuyama K, Saitoh K, Kosihba M.

Opt Express. 2012 Dec 17;20(27):28398-408. doi: 10.1364/OE.20.028398.

PMID:
23263075
23.

Large-effective-area uncoupled few-mode multi-core fiber.

Sasaki Y, Takenaga K, Guan N, Matsuo S, Saitoh K, Koshiba M.

Opt Express. 2012 Dec 10;20(26):B77-84. doi: 10.1364/OE.20.000B77.

PMID:
23262916
24.

Low expression of nucleus accumbens-associated protein 1 predicts poor prognosis for patients with pancreatic ductal adenocarcinoma.

Nishi T, Maruyama R, Urano T, Nakayama N, Kawabata Y, Yano S, Yoshida M, Nakayama K, Miyazaki K, Takenaga K, Tanaka T, Tajima Y.

Pathol Int. 2012 Dec;62(12):802-10. doi: 10.1111/pin.12020.

PMID:
23252869
25.

Regulation of metastasis; mitochondrial DNA mutations have appeared on stage.

Ishikawa K, Imanishi H, Takenaga K, Hayashi J.

J Bioenerg Biomembr. 2012 Dec;44(6):639-44. doi: 10.1007/s10863-012-9468-6. Review.

PMID:
22895836
26.

Attenuation of reactive oxygen species by antioxidants suppresses hypoxia-induced epithelial-mesenchymal transition and metastasis of pancreatic cancer cells.

Shimojo Y, Akimoto M, Hisanaga T, Tanaka T, Tajima Y, Honma Y, Takenaga K.

Clin Exp Metastasis. 2013 Feb;30(2):143-54. doi: 10.1007/s10585-012-9519-8. Epub 2012 Jul 26.

PMID:
22833345
27.

Design and analysis of large-effective-area heterogeneous trench-assisted multi-core fiber.

Tu J, Saitoh K, Koshiba M, Takenaga K, Matsuo S.

Opt Express. 2012 Jul 2;20(14):15157-70. doi: 10.1364/OE.20.015157.

PMID:
22772214
28.

Effectively single-mode all-solid photonic bandgap fiber with large effective area and low bending loss for compact high-power all-fiber lasers.

Kashiwagi M, Saitoh K, Takenaga K, Tanigawa S, Matsuo S, Fujimaki M.

Opt Express. 2012 Jul 2;20(14):15061-70. doi: 10.1364/OE.20.015061.

PMID:
22772202
29.

Specific mitochondrial DNA mutation in mice regulates diabetes and lymphoma development.

Hashizume O, Shimizu A, Yokota M, Sugiyama A, Nakada K, Miyoshi H, Itami M, Ohira M, Nagase H, Takenaga K, Hayashi J.

Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):10528-33. doi: 10.1073/pnas.1202367109. Epub 2012 Jun 11.

30.

1000-km 7-core fiber transmission of 10 x 96-Gb/s PDM-16QAM using Raman amplification with 6.5 W per fiber.

Takara H, Ono H, Abe Y, Masuda H, Takenaga K, Matsuo S, Kubota H, Shibahara K, Kobayashi T, Miaymoto Y.

Opt Express. 2012 Apr 23;20(9):10100-5. doi: 10.1364/OE.20.010100.

PMID:
22535101
31.

Low bending loss and effectively single-mode all-solid photonic bandgap fiber with an effective area of 650 μm2.

Kashiwagi M, Saitoh K, Takenaga K, Tanigawa S, Matsuo S, Fujimaki M.

Opt Lett. 2012 Apr 15;37(8):1292-4. doi: 10.1364/OL.37.001292.

PMID:
22513663
32.

Selective mode excitation and discrimination of four-core homogeneous coupled multi-core fiber.

Kokubun Y, Komo T, Takenaga K, Tanigawa S, Matsuo S.

Opt Express. 2011 Dec 12;19(26):B905-14. doi: 10.1364/OE.19.00B905.

PMID:
22274119
33.

A large effective area multi-core fiber with an optimized cladding thickness.

Takenaga K, Arakawa Y, Sasaki Y, Tanigawa S, Matsuo S, Saitoh K, Koshiba M.

Opt Express. 2011 Dec 12;19(26):B543-50. doi: 10.1364/OE.19.00B543.

PMID:
22274068
34.

Multi-core fiber design and analysis: coupled-mode theory and coupled-power theory.

Koshiba M, Saitoh K, Takenaga K, Matsuo S.

Opt Express. 2011 Dec 12;19(26):B102-11. doi: 10.1364/OE.19.00B102.

PMID:
22274004
35.

A novel fusicoccin derivative preferentially targets hypoxic tumor cells and inhibits tumor growth in xenografts.

Kawakami K, Hattori M, Inoue T, Maruyama Y, Ohkanda J, Kato N, Tongu M, Yamada T, Akimoto M, Takenaga K, Sassa T, Suzumiy J, Honma Y.

Anticancer Agents Med Chem. 2012 Sep;12(7):791-800.

PMID:
22263802
36.

Large-effective-area ten-core fiber with cladding diameter of about 200 μm.

Matsuo S, Takenaga K, Arakawa Y, Sasaki Y, Taniagwa S, Saitoh K, Koshiba M.

Opt Lett. 2011 Dec 1;36(23):4626-8. doi: 10.1364/OL.36.004626.

PMID:
22139264
37.

Hydrogen sulfide inhibits hypoxia- but not anoxia-induced hypoxia-inducible factor 1 activation in a von hippel-lindau- and mitochondria-dependent manner.

Kai S, Tanaka T, Daijo H, Harada H, Kishimoto S, Suzuki K, Takabuchi S, Takenaga K, Fukuda K, Hirota K.

Antioxid Redox Signal. 2012 Feb 1;16(3):203-16. doi: 10.1089/ars.2011.3882. Epub 2011 Oct 17.

38.

Mitochondrial DNA mutations regulate metastasis of human breast cancer cells.

Imanishi H, Hattori K, Wada R, Ishikawa K, Fukuda S, Takenaga K, Nakada K, Hayashi J.

PLoS One. 2011;6(8):e23401. doi: 10.1371/journal.pone.0023401. Epub 2011 Aug 11.

39.

UV-induced Bragg grating inscription into single-polarization all-solid hybrid microstructured optical fiber.

Goto R, Fsaifes I, Baz A, Bigot L, Takenaga K, Matsuo S, Jackson SD.

Opt Express. 2011 Jul 4;19(14):13525-30. doi: 10.1364/OE.19.013525.

PMID:
21747507
40.

Angiogenic signaling aberrantly induced by tumor hypoxia.

Takenaga K.

Front Biosci (Landmark Ed). 2011 Jan 1;16:31-48. Review.

PMID:
21196157
41.

Cyclopamine induces eosinophilic differentiation and upregulates CD44 expression in myeloid leukemia cells.

Takahashi T, Kawakami K, Mishima S, Akimoto M, Takenaga K, Suzumiya J, Honma Y.

Leuk Res. 2011 May;35(5):638-45. doi: 10.1016/j.leukres.2010.09.022. Epub 2010 Oct 23.

PMID:
20971508
42.

The innate immune system in host mice targets cells with allogenic mitochondrial DNA.

Ishikawa K, Toyama-Sorimachi N, Nakada K, Morimoto M, Imanishi H, Yoshizaki M, Sasawatari S, Niikura M, Takenaga K, Yonekawa H, Hayashi J.

J Exp Med. 2010 Oct 25;207(11):2297-305. doi: 10.1084/jem.20092296. Epub 2010 Oct 11.

43.

Generation of trans-mitochondrial mito-mice by the introduction of a pathogenic G13997A mtDNA from highly metastatic lung carcinoma cells.

Yokota M, Shitara H, Hashizume O, Ishikawa K, Nakada K, Ishii R, Taya C, Takenaga K, Yonekawa H, Hayashi J.

FEBS Lett. 2010 Sep 24;584(18):3943-8. doi: 10.1016/j.febslet.2010.07.048. Epub 2010 Aug 3.

44.

Observation of a propagation mode of a fiber fuse with a long-period damage track in hole-assisted fiber.

Hanzawa N, Kurokawa K, Tsujikawa K, Takenaga K, Tanigawa S, Matsuo S, Tomita S.

Opt Lett. 2010 Jun 15;35(12):2004-6. doi: 10.1364/OL.35.002004.

PMID:
20548367
45.

MCL-1V, a novel mouse antiapoptotic MCL-1 variant, generated by RNA splicing at a non-canonical splicing pair.

Kojima S, Hyakutake A, Koshikawa N, Nakagawara A, Takenaga K.

Biochem Biophys Res Commun. 2010 Jan 1;391(1):492-7. doi: 10.1016/j.bbrc.2009.11.086. Epub 2009 Nov 15.

PMID:
19919825
46.

Single-polarization operation in birefringent all-solid hybrid microstructured fiber with additional stress applying parts.

Goto R, Jackson SD, Takenaga K.

Opt Lett. 2009 Oct 15;34(20):3119-21. doi: 10.1364/OL.34.003119.

PMID:
19838245
47.
48.

Enhanced glycolysis induced by mtDNA mutations does not regulate metastasis.

Ishikawa K, Hashizume O, Koshikawa N, Fukuda S, Nakada K, Takenaga K, Hayashi J.

FEBS Lett. 2008 Oct 15;582(23-24):3525-30. doi: 10.1016/j.febslet.2008.09.024. Epub 2008 Sep 19.

49.

Reversible regulation of metastasis by ROS-generating mtDNA mutations.

Ishikawa K, Koshikawa N, Takenaga K, Nakada K, Hayashi J.

Mitochondrion. 2008 Sep;8(4):339-44. doi: 10.1016/j.mito.2008.07.006. Epub 2008 Aug 8. Review.

PMID:
18727959
50.

ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis.

Ishikawa K, Takenaga K, Akimoto M, Koshikawa N, Yamaguchi A, Imanishi H, Nakada K, Honma Y, Hayashi J.

Science. 2008 May 2;320(5876):661-4. doi: 10.1126/science.1156906. Epub 2008 Apr 3.

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