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Items: 1 to 50 of 616

1.

Restriction of PD-1 function by cis-PD-L1/CD80 interactions is required for optimal T cell responses.

Sugiura D, Maruhashi T, Okazaki IM, Shimizu K, Maeda TK, Takemoto T, Okazaki T.

Science. 2019 May 10;364(6440):558-566. doi: 10.1126/science.aav7062. Epub 2019 Apr 18.

PMID:
31000591
2.

Antimicrobial resistance profiles of vancomycin-resistant Enterococcus species isolated from laboratory mice.

Yamanaka H, Kadomatsu R, Takagi T, Ohsawa M, Yamamoto N, Kubo N, Takemoto T, Ohsawa K.

J Vet Sci. 2019 Mar;20(2):e13. doi: 10.4142/jvs.2019.20.e13. Epub 2019 Mar 15.

3.

Hoxa13 regulates expression of common Hox target genes involved in cartilage development to coordinate the expansion of the autopodal anlage.

Yamamoto S, Uchida Y, Ohtani T, Nozaki E, Yin C, Gotoh Y, Yakushiji-Kaminatsui N, Higashiyama T, Suzuki T, Takemoto T, Shiraishi YI, Kuroiwa A.

Dev Growth Differ. 2019 Apr;61(3):228-251. doi: 10.1111/dgd.12601. Epub 2019 Mar 20.

PMID:
30895612
4.

Life-threatening complications after pulmonary resection for lung cancer in patients on chronic hemodialysis.

Tomizawa K, Sato K, Ohara S, Fujino T, Koga T, Nishino M, Kobayashi Y, Chiba M, Shimoji M, Suda K, Takemoto T, Mitsudomi T.

Surg Today. 2019 Jun;49(6):513-520. doi: 10.1007/s00595-019-1773-9. Epub 2019 Jan 31.

PMID:
30706240
5.

Custom-made hinged knee braces with extension support can improve dynamic balance.

Ochi A, Ohko H, Ota S, Shimoichi N, Takemoto T, Mitsuke K.

J Exerc Sci Fit. 2018 Dec;16(3):94-98. doi: 10.1016/j.jesf.2018.08.002. Epub 2018 Sep 4.

6.

Activity of a novel HER2 inhibitor, poziotinib, for HER2 exon 20 mutations in lung cancer and mechanism of acquired resistance: An in vitro study.

Koga T, Kobayashi Y, Tomizawa K, Suda K, Kosaka T, Sesumi Y, Fujino T, Nishino M, Ohara S, Chiba M, Shimoji M, Takemoto T, Suzuki M, Jänne PA, Mitsudomi T.

Lung Cancer. 2018 Dec;126:72-79. doi: 10.1016/j.lungcan.2018.10.019. Epub 2018 Oct 17.

PMID:
30527195
7.

Effects of secondary EGFR mutations on resistance against upfront osimertinib in cells with EGFR-activating mutations in vitro.

Nishino M, Suda K, Kobayashi Y, Ohara S, Fujino T, Koga T, Chiba M, Shimoji M, Tomizawa K, Takemoto T, Mitsudomi T.

Lung Cancer. 2018 Dec;126:149-155. doi: 10.1016/j.lungcan.2018.10.026. Epub 2018 Oct 31.

PMID:
30527179
8.

Generation of PDX-1 mutant porcine blastocysts by introducing CRISPR/Cas9-system into porcine zygotes via electroporation.

Tanihara F, Hirata M, Nguyen NT, Le QA, Hirano T, Takemoto T, Nakai M, Fuchimoto DI, Otoi T.

Anim Sci J. 2019 Jan;90(1):55-61. doi: 10.1111/asj.13129. Epub 2018 Oct 25.

PMID:
30368976
9.

Generation of a TP53-modified porcine cancer model by CRISPR/Cas9-mediated gene modification in porcine zygotes via electroporation.

Tanihara F, Hirata M, Nguyen NT, Le QA, Hirano T, Takemoto T, Nakai M, Fuchimoto DI, Otoi T.

PLoS One. 2018 Oct 23;13(10):e0206360. doi: 10.1371/journal.pone.0206360. eCollection 2018.

10.

Changes in bacterial number at different sites of oral cavity during perioperative oral care management in gastrointestinal cancer patients: preliminary study.

Kawano T, Shigeishi H, Fukada E, Yanagisawa T, Kuroda N, Takemoto T, Sugiyama M.

J Appl Oral Sci. 2018 Jun 18;26:e20170516. doi: 10.1590/1678-7757-2017-0516.

11.

Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration.

Harada A, Maehara K, Ono Y, Taguchi H, Yoshioka K, Kitajima Y, Xie Y, Sato Y, Iwasaki T, Nogami J, Okada S, Komatsu T, Semba Y, Takemoto T, Kimura H, Kurumizaka H, Ohkawa Y.

Nat Commun. 2018 Apr 11;9(1):1400. doi: 10.1038/s41467-018-03845-1.

12.

EGFR T790M and C797S Mutations as Mechanisms of Acquired Resistance to Dacomitinib.

Kobayashi Y, Fujino T, Nishino M, Koga T, Chiba M, Sesumi Y, Ohara S, Shimoji M, Tomizawa K, Takemoto T, Mitsudomi T.

J Thorac Oncol. 2018 May;13(5):727-731. doi: 10.1016/j.jtho.2018.01.009. Epub 2018 Feb 2.

PMID:
29410323
13.

[A Case of Resected Superior Sulcus Tumor with Pathological Complete Response after Trimodality Therapy].

Nishino M, Tomizawa K, Ohara S, Fujino T, Sesumi Y, Koga T, Sato K, Kobayashi Y, Chiba M, Shimoji M, Takemoto T, Mitsudomi T.

Gan To Kagaku Ryoho. 2018 Jan;45(1):103-105. Japanese.

PMID:
29362322
14.

Dental hygienists' perceptions of professionalism are multidimensional and context-dependent: a qualitative study in Japan.

Nagatani Y, Imafuku R, Takemoto T, Waki T, Obayashi T, Ogawa T.

BMC Med Educ. 2017 Dec 29;17(1):267. doi: 10.1186/s12909-017-1107-9.

15.

Clinical significance of tumor cavitation in surgically resected early-stage primary lung cancer.

Tomizawa K, Shimizu S, Ohara S, Fujino T, Nishino M, Sesumi Y, Kobayashi Y, Sato K, Chiba M, Shimoji M, Suda K, Takemoto T, Mitsudomi T.

Lung Cancer. 2017 Oct;112:57-61. doi: 10.1016/j.lungcan.2017.08.004. Epub 2017 Aug 4.

PMID:
29191601
16.

Effects of voltage strength during electroporation on the development and quality of in vitro-produced porcine embryos.

Nishio K, Tanihara F, Nguyen TV, Kunihara T, Nii M, Hirata M, Takemoto T, Otoi T.

Reprod Domest Anim. 2018 Apr;53(2):313-318. doi: 10.1111/rda.13106. Epub 2017 Nov 14.

PMID:
29135047
17.

[Early Postoperative Hemodynamics of Mitral Valvuloplasty Using Colvin-Galloway Future Band].

Funahashi R, Okada Y, Muro T, Inanami H, Takemoto T.

Kyobu Geka. 2017 Aug;70(9):737-741. Japanese.

PMID:
28790238
18.

Predictors of biologic discontinuation due to insufficient response in patients with rheumatoid arthritis who achieved clinical remission with biologic treatment: A multicenter observational cohort study.

Asai S, Fujibayashi T, Oguchi T, Hanabayashi M, Hayashi M, Matsubara H, Ito T, Yabe Y, Watanabe T, Hirano Y, Kanayama Y, Kaneko A, Kato T, Takagi H, Takahashi N, Funahashi K, Takemoto T, Asai N, Watanabe T, Ishiguro N, Kojima T.

Mod Rheumatol. 2018 Mar;28(2):221-226. doi: 10.1080/14397595.2017.1332558. Epub 2017 Jul 13.

PMID:
28701065
19.

Sensitivity of the meiotic stage to hyperthermia during in vitro maturation of porcine oocytes.

Nishio K, Yamazaki M, Taniguchi M, Besshi K, Morita F, Kunihara T, Tanihara F, Takemoto T, Otoi T.

Acta Vet Hung. 2017 Mar;65(1):115-123. doi: 10.1556/004.2017.012.

PMID:
28244334
20.

Effect of dasatinib on EMT-mediated-mechanism of resistance against EGFR inhibitors in lung cancer cells.

Sesumi Y, Suda K, Mizuuchi H, Kobayashi Y, Sato K, Chiba M, Shimoji M, Tomizawa K, Takemoto T, Mitsudomi T.

Lung Cancer. 2017 Feb;104:85-90. doi: 10.1016/j.lungcan.2016.12.012. Epub 2016 Dec 21.

PMID:
28213007
21.

Foxn1-β5t transcriptional axis controls CD8+ T-cell production in the thymus.

Uddin MM, Ohigashi I, Motosugi R, Nakayama T, Sakata M, Hamazaki J, Nishito Y, Rode I, Tanaka K, Takemoto T, Murata S, Takahama Y.

Nat Commun. 2017 Feb 8;8:14419. doi: 10.1038/ncomms14419.

22.

Prognostic impact of pleural lavage cytology in patients with primary lung cancer.

Tomizawa K, Nishino M, Sesumi Y, Kobayashi Y, Sato K, Chiba M, Shimoji M, Suda K, Shimizu S, Sato T, Takemoto T, Mitsudomi T.

Lung Cancer. 2016 Dec;102:60-64. doi: 10.1016/j.lungcan.2016.10.009. Epub 2016 Oct 24.

PMID:
27987590
23.

CHARACTERISTICS AND FERTILITY OF SUMATRAN TIGER SPERMATOZOA CRYOPRESERVED WITH DIFFERENT SUGARS.

Wayan Kurniani Karja N, Fahrudin M, Setiadi MA, Tumbelaka LI, Sudarwati R, Hastuti YT, Mulia BH, Widianti A, Sultan K, Terazono T, Namula Z, Taniguchi M, Tanihara F, Takemoto T, Kikuchi K, Sato Y, Otoi T.

Cryo Letters. 2016 Jul/Aug;37(4):264-271.

PMID:
27925009
24.

Characterization of EGFR T790M, L792F, and C797S Mutations as Mechanisms of Acquired Resistance to Afatinib in Lung Cancer.

Kobayashi Y, Azuma K, Nagai H, Kim YH, Togashi Y, Sesumi Y, Chiba M, Shimoji M, Sato K, Tomizawa K, Takemoto T, Nishio K, Mitsudomi T.

Mol Cancer Ther. 2017 Feb;16(2):357-364. doi: 10.1158/1535-7163.MCT-16-0407. Epub 2016 Dec 2.

25.

Impact of alcohol intake on the relationships of uric acid with blood pressure and cardiac hypertrophy in essential hypertension.

Seki S, Oki Y, Tsunoda S, Takemoto T, Koyama T, Yoshimura M.

J Cardiol. 2016 Nov;68(5):447-454. doi: 10.1016/j.jjcc.2015.11.006. Epub 2015 Dec 12.

26.

Somatic cell reprogramming-free generation of genetically modified pigs.

Tanihara F, Takemoto T, Kitagawa E, Rao S, Do LT, Onishi A, Yamashita Y, Kosugi C, Suzuki H, Sembon S, Suzuki S, Nakai M, Hashimoto M, Yasue A, Matsuhisa M, Noji S, Fujimura T, Fuchimoto D, Otoi T.

Sci Adv. 2016 Sep 14;2(9):e1600803. doi: 10.1126/sciadv.1600803. eCollection 2016 Sep.

27.

Effects of duration of electric pulse on in vitro development of cloned cat embryos with human artificial chromosome vector.

Do L, Wittayarat M, Terazono T, Sato Y, Taniguchi M, Tanihara F, Takemoto T, Kazuki Y, Kazuki K, Oshimura M, Otoi T.

Reprod Domest Anim. 2016 Dec;51(6):1039-1043. doi: 10.1111/rda.12766. Epub 2016 Aug 28.

PMID:
27568550
28.

Electroporation of Cas9 protein/sgRNA into early pronuclear zygotes generates non-mosaic mutants in the mouse.

Hashimoto M, Yamashita Y, Takemoto T.

Dev Biol. 2016 Oct 1;418(1):1-9. doi: 10.1016/j.ydbio.2016.07.017. Epub 2016 Jul 26.

29.

Clinical and pathologic features of lung cancer expressing programmed cell death ligand 1 (PD-L1).

Shimoji M, Shimizu S, Sato K, Suda K, Kobayashi Y, Tomizawa K, Takemoto T, Mitsudomi T.

Lung Cancer. 2016 Aug;98:69-75. doi: 10.1016/j.lungcan.2016.04.021. Epub 2016 May 25.

PMID:
27393509
30.

Effects of sex steroid hormones and their metabolites on neuronal injury caused by oxygen-glucose deprivation/reoxygenation in organotypic hippocampal slice cultures.

Ishihara Y, Fujitani N, Sakurai H, Takemoto T, Ikeda-Ishihara N, Mori-Yasumoto K, Nehira T, Ishida A, Yamazaki T.

Steroids. 2016 Sep;113:71-7. doi: 10.1016/j.steroids.2016.06.004. Epub 2016 Jul 5.

PMID:
27389922
31.

Axial level-dependent molecular and cellular mechanisms underlying the genesis of the embryonic neural plate.

Kondoh H, Takada S, Takemoto T.

Dev Growth Differ. 2016 Jun;58(5):427-36. doi: 10.1111/dgd.12295. Epub 2016 Jun 9. Review.

PMID:
27279156
32.

Simvastatin inhibits CD44 fragmentation in chondrocytes.

Terabe K, Takahashi N, Takemoto T, Knudson W, Ishiguro N, Kojima T.

Arch Biochem Biophys. 2016 Aug 15;604:1-10. doi: 10.1016/j.abb.2016.05.019. Epub 2016 May 28.

PMID:
27242325
33.

Clinical, Pathological, and Molecular Features of Lung Adenocarcinomas with AXL Expression.

Sato K, Suda K, Shimizu S, Sakai K, Mizuuchi H, Tomizawa K, Takemoto T, Nishio K, Mitsudomi T.

PLoS One. 2016 Apr 21;11(4):e0154186. doi: 10.1371/journal.pone.0154186. eCollection 2016.

34.

R26-WntVis reporter mice showing graded response to Wnt signal levels.

Takemoto T, Abe T, Kiyonari H, Nakao K, Furuta Y, Suzuki H, Takada S, Fujimori T, Kondoh H.

Genes Cells. 2016 Jun;21(6):661-9. doi: 10.1111/gtc.12364. Epub 2016 Mar 31.

35.

The optimal period of Ca-EDTA treatment for parthenogenetic activation of porcine oocytes during maturation culture.

Morita Y, Taniguchi M, Tanihara F, Ito A, Namula Z, DO LT, Takagi M, Takemoto T, Otoi T.

J Vet Med Sci. 2016 Jul 1;78(6):1019-23. doi: 10.1292/jvms.15-0658. Epub 2016 Mar 4.

36.

Improved safety of biologic therapy for rheumatoid arthritis over the 8-year period since implementation in Japan: long-term results from a multicenter observational cohort study.

Kojima T, Takahashi N, Funahashi K, Asai S, Terabe K, Kaneko A, Hirano Y, Hayashi M, Miyake H, Oguchi T, Takagi H, Kanayama Y, Yabe Y, Watanabe T, Fujibayashi T, Shioura T, Ito T, Yoshioka Y, Ishikawa H, Asai N, Takemoto T, Kojima M, Ishiguro N.

Clin Rheumatol. 2016 Apr;35(4):863-71. doi: 10.1007/s10067-016-3201-5. Epub 2016 Feb 5.

PMID:
26846135
37.

Oncogene swap as a novel mechanism of acquired resistance to epidermal growth factor receptor-tyrosine kinase inhibitor in lung cancer.

Mizuuchi H, Suda K, Murakami I, Sakai K, Sato K, Kobayashi Y, Shimoji M, Chiba M, Sesumi Y, Tomizawa K, Takemoto T, Sekido Y, Nishio K, Mitsudomi T.

Cancer Sci. 2016 Apr;107(4):461-8. doi: 10.1111/cas.12905. Epub 2016 Mar 28.

38.

Factors affecting pregnancy outcomes in young women treated with fertility-preserving therapy for well-differentiated endometrial cancer or atypical endometrial hyperplasia.

Inoue O, Hamatani T, Susumu N, Yamagami W, Ogawa S, Takemoto T, Hirasawa A, Banno K, Kuji N, Tanaka M, Aoki D.

Reprod Biol Endocrinol. 2016 Jan 15;14:2. doi: 10.1186/s12958-015-0136-7.

39.

Medical care ideals among urban and rural residents in Thailand: a qualitative study.

Ikai T, Yamtree S, Takemoto T, Tamura T, Kanayama H, Sato K, Kusaka Y, Hayashi H, Terasawa H.

Int J Equity Health. 2016 Jan 5;15:2. doi: 10.1186/s12939-015-0292-6.

40.

Predictive factors for achieving low disease activity at 52 weeks after switching from tumor necrosis factor inhibitors to abatacept: results from a multicenter observational cohort study of Japanese patients.

Kojima T, Takahashi N, Kaneko A, Kida D, Hirano Y, Fujibayashi T, Yabe Y, Takagi H, Oguchi T, Miyake H, Kato T, Watanabe T, Hayashi M, Shioura T, Kanayama Y, Funahashi K, Asai S, Yoshioka Y, Terabe K, Takemoto T, Asai N, Ishiguro N.

Clin Rheumatol. 2016 Jan;35(1):219-25. doi: 10.1007/s10067-015-3135-3. Epub 2015 Dec 3.

PMID:
26631102
41.

Prognosis and segment-specific nodal spread of primary lung cancer in the right lower lobe.

Tomizawa K, Suda K, Takemoto T, Mizuno T, Kuroda H, Sakakura N, Iwasaki T, Sakaguchi M, Kuwano H, Mitsudomi T, Sakao Y.

Thorac Cancer. 2015 Nov;6(6):672-7. doi: 10.1111/1759-7714.12235. Epub 2015 Feb 27.

42.

Patient-reported outcomes as assessment tools and predictors of long-term prognosis: a 7-year follow-up study of patients with rheumatoid arthritis.

Kojima M, Kojima T, Suzuki S, Takahashi N, Funahashi K, Asai S, Yoshioka Y, Terabe K, Asai N, Takemoto T, Ishiguro N.

Int J Rheum Dis. 2017 Sep;20(9):1193-1200. doi: 10.1111/1756-185X.12789. Epub 2015 Nov 6.

PMID:
26544115
43.

Progression after spontaneous regression in lung large cell neuroendocrine carcinoma: Report of a curative resection.

Tomizawa K, Suda K, Takemoto T, Iwasaki T, Sakaguchi M, Kuwano H, Mitsudomi T.

Thorac Cancer. 2015 Sep;6(5):655-8. doi: 10.1111/1759-7714.12201. Epub 2015 Jan 8.

44.

Concomitant Methotrexate Protects Against Total Knee Arthroplasty in Patients with Rheumatoid Arthritis Treated with Tumor Necrosis Factor Inhibitors.

Asai S, Takahashi N, Funahashi K, Yoshioka Y, Takemoto T, Terabe K, Asai N, Ishiguro N, Kojima T.

J Rheumatol. 2015 Dec;42(12):2255-60. doi: 10.3899/jrheum.150410. Epub 2015 Oct 1.

PMID:
26428206
45.

Erratum: Electroporation enables the efficient mRNA delivery into the mouse zygotes and facilitates CRISPR/Cas9-based genome editing.

Hashimoto M, Takemoto T.

Sci Rep. 2015 Aug 5;5:12658. doi: 10.1038/srep12658. No abstract available.

46.

Dual role of superoxide dismutase 2 induced in activated microglia: oxidative stress tolerance and convergence of inflammatory responses.

Ishihara Y, Takemoto T, Itoh K, Ishida A, Yamazaki T.

J Biol Chem. 2015 Sep 11;290(37):22805-17. doi: 10.1074/jbc.M115.659151. Epub 2015 Jul 31.

47.

EGFR Exon 18 Mutations in Lung Cancer: Molecular Predictors of Augmented Sensitivity to Afatinib or Neratinib as Compared with First- or Third-Generation TKIs.

Kobayashi Y, Togashi Y, Yatabe Y, Mizuuchi H, Jangchul P, Kondo C, Shimoji M, Sato K, Suda K, Tomizawa K, Takemoto T, Hida T, Nishio K, Mitsudomi T.

Clin Cancer Res. 2015 Dec 1;21(23):5305-13. doi: 10.1158/1078-0432.CCR-15-1046. Epub 2015 Jul 23.

48.

Neuroprotection elicited by nerve growth factor and brain-derived neurotrophic factor released from astrocytes in response to methylmercury.

Takemoto T, Ishihara Y, Ishida A, Yamazaki T.

Environ Toxicol Pharmacol. 2015 Jul;40(1):199-205. doi: 10.1016/j.etap.2015.06.010. Epub 2015 Jun 9.

PMID:
26143513
49.

Disease activity early in treatment as a predictor of future low disease activity in RA patients treated with iguratimod.

Yoshioka Y, Takahashi N, Kaneko A, Hirano Y, Kanayama Y, Kanda H, Takagi H, Ito T, Kato T, Saito K, Funahashi K, Asai S, Takemoto T, Terabe K, Asai N, Ishiguro N, Kojima T.

Mod Rheumatol. 2016;26(2):169-74. doi: 10.3109/14397595.2015.1069475. Epub 2015 Aug 19.

PMID:
26140467
50.

Helicobacter sp. MIT 01-6451 infection during fetal and neonatal life in laboratory mice.

Yamanaka H, Nakanishi T, Takagi T, Ohsawa M, Kubo N, Yamamoto N, Takemoto T, Ohsawa K.

Exp Anim. 2015;64(4):375-82. doi: 10.1538/expanim.15-0034. Epub 2015 Jul 2.

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