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Items: 1 to 50 of 224

1.

7-Spiroindanyl derivatives of naltrexone and oxymorphone as selective ligands for delta opioid receptors.

Ohkawa S, DiGiacomo B, Larson DL, Takemori AE, Portoghese PS.

J Med Chem. 1997 May 23;40(11):1720-5.

PMID:
9171881
2.

Spinal delta opioid receptor subtype activity of 6-monoacetylmorphine in Swiss Webster mice.

Rady JJ, Baemmert D, Takemori AE, Portoghese PS, Fujimoto JM.

Pharmacol Biochem Behav. 1997 Feb;56(2):243-9.

PMID:
9050081
4.

Opioid antagonist activity of naltrexone-derived bivalent ligands: importance of a properly oriented molecular scaffold to guide "address" recognition at kappa opioid receptors.

Bolognesi ML, Ojala WH, Gleason WB, Griffin JF, Farouz-Grant F, Larson DL, Takemori AE, Portoghese PS.

J Med Chem. 1996 Apr 26;39(9):1816-22.

PMID:
8627605
5.

Arylacetamide-derived fluorescent probes: synthesis, biological evaluation, and direct fluorescent labeling of kappa opioid receptors in mouse microglial cells.

Chang AC, Chao CC, Takemori AE, Gekker G, Hu S, Peterson PK, Portoghese PS.

J Med Chem. 1996 Apr 12;39(8):1729-35.

PMID:
8648612
6.

Cold water swim stress- and delta-2 opioid-induced analgesia are modulated by spinal gamma-aminobutyric acidA receptors.

Killian P, Holmes BB, Takemori AE, Portoghese PS, Fujimoto JM.

J Pharmacol Exp Ther. 1995 Aug;274(2):730-4.

PMID:
7636735
7.

Electrophilic N-benzylnaltrindoles as delta opioid receptor-selective antagonists.

Korlipara VL, Takemori AE, Portoghese PS.

J Med Chem. 1995 Apr 14;38(8):1337-43.

PMID:
7731019
9.

kappa Opioid receptor selective affinity labels: electrophilic benzeneacetamides as kappa-selective opioid antagonists.

Chang AC, Takemori AE, Ojala WH, Gleason WB, Portoghese PS.

J Med Chem. 1994 Dec 23;37(26):4490-8.

PMID:
7799399
10.

Lack of involvement of delta-1 opioid receptors in the development of physical dependence on morphine in mice.

Miyamoto Y, Bowen WD, Portoghese PS, Takemori AE.

J Pharmacol Exp Ther. 1994 Jul;270(1):37-9.

PMID:
8035333
11.

Synthesis and delta-opioid receptor antagonist activity of a naltrindole analogue with a regioisomeric indole moiety.

Portoghese PS, Ohkawa S, Moe ST, Takemori AE.

J Med Chem. 1994 Jun 10;37(12):1886-8.

PMID:
8021929
12.

N-benzylnaltrindoles as long-acting delta-opioid receptor antagonists.

Korlipara VL, Takemori AE, Portoghese PS.

J Med Chem. 1994 Jun 10;37(12):1882-5.

PMID:
8021928
15.

Synthesis of naltrexone-derived delta-opioid antagonists. Role of conformation of the delta address moiety.

Portoghese PS, Sultana M, Moe ST, Takemori AE.

J Med Chem. 1994 Mar 4;37(5):579-85.

PMID:
8126697
16.

Interaction of [D-Pen2,D-Pen5]enkephalin and [D-Ala2,Glu4]deltorphin with delta-opioid receptor subtypes in vivo.

Vanderah T, Takemori AE, Sultana M, Portoghese PS, Mosberg HI, Hruby VJ, Haaseth RC, Matsunaga TO, Porreca F.

Eur J Pharmacol. 1994 Feb 3;252(2):133-7.

17.

Supraspinal delta receptor subtype activity of heroin and 6-monoacetylmorphine in Swiss Webster mice.

Rady JJ, Takemori AE, Portoghese PS, Fujimoto JM.

Life Sci. 1994;55(8):603-9.

PMID:
8046996
18.

Possible contribution of a glutathione conjugate to the long-duration action of beta-funaltrexamine.

Larson DL, Hua M, Takemori AE, Portoghese PS.

J Med Chem. 1993 Nov 12;36(23):3669-73.

PMID:
8246236
19.

3,4-Dimethyl-4-(3-hydroxyphenyl)piperidines: opioid antagonists with potent anorectant activity.

Mitch CH, Leander JD, Mendelsohn LG, Shaw WN, Wong DT, Cantrell BE, Johnson BG, Reel JK, Snoddy JD, Takemori AE, et al.

J Med Chem. 1993 Oct 1;36(20):2842-50.

PMID:
8410999
20.

Modulation of morphine antinociception by swim-stress in the mouse: involvement of supraspinal opioid delta-2 receptors.

Vanderah TW, Wild KD, Takemori AE, Sultana M, Portoghese PS, Bowen WD, Hruby VJ, Mosberg HI, Porreca F.

J Pharmacol Exp Ther. 1993 Oct;267(1):449-55.

PMID:
8229774
21.
22.
24.
25.

Involvement of delta 2 opioid receptors in acute dependence on morphine in mice.

Miyamoto Y, Portoghese PS, Takemori AE.

J Pharmacol Exp Ther. 1993 Jun;265(3):1325-7.

PMID:
8389861
26.

Effect of antagonists selective for mu, delta and kappa opioid receptors on the reinforcing effects of heroin in rats.

Negus SS, Henriksen SJ, Mattox A, Pasternak GW, Portoghese PS, Takemori AE, Weinger MB, Koob GF.

J Pharmacol Exp Ther. 1993 Jun;265(3):1245-52.

PMID:
8389859
28.

Involvement of delta 2 opioid receptors in the development of morphine dependence in mice.

Miyamoto Y, Portoghese PS, Takemori AE.

J Pharmacol Exp Ther. 1993 Mar;264(3):1141-5.

PMID:
8383738
29.

Evidence for a single functional opioid delta receptor subtype in the mouse isolated vas deferens.

Wild KD, Carlisi VJ, Mosberg HI, Bowen WD, Portoghese PS, Sultana M, Takemori AE, Hruby VJ, Porreca F.

J Pharmacol Exp Ther. 1993 Feb;264(2):831-8.

PMID:
8382281
32.

The mixed antinociceptive agonist-antagonist activity of beta-endorphin(1-27) in mice.

Takemori AE, Portoghese PS.

Life Sci. 1993;53(13):1049-52.

PMID:
8396188
33.

7-Benzylidenenaltrexone (BNTX): a selective delta 1 opioid receptor antagonist in the mouse spinal cord.

Sofuoglu M, Portoghese PS, Takemori AE.

Life Sci. 1993;52(8):769-75.

PMID:
8383271
34.
35.

Differential antagonism by naltrindole-5'-isothiocyanate on [3H]DSLET and [3H]DPDPE binding to striatal slices of mice.

Chakrabarti S, Sultana M, Portoghese PS, Takemori AE.

Life Sci. 1993;53(23):1761-5.

PMID:
8246672
36.

Opioid agonist and antagonist activities of morphindoles related to naltrindole.

Portoghese PS, Larson DL, Sultana M, Takemori AE.

J Med Chem. 1992 Nov 13;35(23):4325-9.

PMID:
1333013
37.
38.

Delta opioid antagonist activity and binding studies of regioisomeric isothiocyanate derivatives of naltrindole: evidence for delta receptor subtypes.

Portoghese PS, Sultana M, Nelson WL, Klein P, Takemori AE.

J Med Chem. 1992 Oct 30;35(22):4086-91.

PMID:
1331455
39.

Suppression by dynorphin A-(1-13) of the expression of opiate withdrawal and tolerance in mice.

Takemori AE, Loh HH, Lee NM.

Eur J Pharmacol. 1992 Oct 20;221(2-3):223-6.

PMID:
1358653
40.

Modulation of mu-mediated antinociception in the mouse involves opioid delta-2 receptors.

Porreca F, Takemori AE, Sultana M, Portoghese PS, Bowen WD, Mosberg HI.

J Pharmacol Exp Ther. 1992 Oct;263(1):147-52.

PMID:
1328602
41.

A highly selective delta 1-opioid receptor antagonist: 7-benzylidenenaltrexone.

Portoghese PS, Sultana M, Nagase H, Takemori AE.

Eur J Pharmacol. 1992 Jul 21;218(1):195-6.

PMID:
1327826
42.

Mediation of swim-stress antinociception by the opioid delta 2 receptor in the mouse.

Vanderah TW, Wild KD, Takemori AE, Sultana M, Portoghese PS, Bowen WD, Mosberg HI, Porreca F.

J Pharmacol Exp Ther. 1992 Jul;262(1):190-7.

PMID:
1320682
43.

delta-Opioid receptor binding in mouse brain: evidence for heterogeneous binding sites.

Sofuoglu M, Portoghese PS, Takemori AE.

Eur J Pharmacol. 1992 Jun 5;216(2):273-7.

PMID:
1327813
44.

Spinal opioid delta antinociception in the mouse: mediation by a 5'-NTII-sensitive delta receptor subtype.

Mattia A, Farmer SC, Takemori AE, Sultana M, Portoghese PS, Mosberg HI, Bowen WD, Porreca F.

J Pharmacol Exp Ther. 1992 Feb;260(2):518-25.

PMID:
1310737
45.

Maintenance of acute morphine tolerance in mice by selective blockage of kappa opioid receptors with norbinaltorphimine.

Sofuoglu M, Portoghese PS, Takemori AE.

Eur J Pharmacol. 1992 Jan 14;210(2):159-62.

PMID:
1318206
47.

Opioid pharmacology a'la mode.

Takemori AE.

NIDA Res Monogr. 1992;119:21-6. No abstract available.

PMID:
1331795
48.

Selective naltrexone-derived opioid receptor antagonists.

Takemori AE, Portoghese PS.

Annu Rev Pharmacol Toxicol. 1992;32:239-69. Review.

PMID:
1318671
49.

Agonist and antagonist activities of ligands derived from naltrexone and oxymorphone.

Takemori AE, Sultana M, Nagase H, Portoghese PS.

Life Sci. 1992;50(20):1491-5.

PMID:
1315896
50.

Selective blockage of delta opioid receptors prevents the development of morphine tolerance and dependence in mice.

Abdelhamid EE, Sultana M, Portoghese PS, Takemori AE.

J Pharmacol Exp Ther. 1991 Jul 1;258(1):299-303.

PMID:
1649297

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