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Items: 1 to 50 of 79

1.

MCRIP1 promotes the expression of lung-surfactant proteins in mice by disrupting CtBP-mediated epigenetic gene silencing.

Weng JS, Nakamura T, Moriizumi H, Takano H, Yao R, Takekawa M.

Commun Biol. 2019 Jun 20;2:227. doi: 10.1038/s42003-019-0478-3. eCollection 2019.

2.

Pharmacokinetics of anticoagulants apixaban, dabigatran, edoxaban and rivaroxaban in elderly Japanese patients with atrial fibrillation treated in one general hospital.

Yamazaki-Nishioka M, Kogiku M, Noda M, Endo S, Takekawa M, Kishi H, Ota M, Notsu Y, Shimizu M, Yamazaki H.

Xenobiotica. 2019 Sep;49(9):1001-1006. doi: 10.1080/00498254.2018.1524188. Epub 2018 Dec 11.

PMID:
30216091
3.

Downregulation of dual-specificity phosphatase 4 enhances cell proliferation and invasiveness in colorectal carcinomas.

Ichimanda M, Hijiya N, Tsukamoto Y, Uchida T, Nakada C, Akagi T, Etoh T, Iha H, Inomata M, Takekawa M, Moriyama M.

Cancer Sci. 2018 Jan;109(1):250-258. doi: 10.1111/cas.13444. Epub 2017 Dec 8.

4.

A guanine derivative as a new MEK inhibitor produced by Streptomyces sp. MK63-43F2.

Iijima M, Kubota Y, Sawa R, Kubota Y, Hatano M, Igarashi M, Kawada M, Momose I, Takekawa M, Shibasaki M.

J Antibiot (Tokyo). 2017 Sep 6. doi: 10.1038/ja.2017.100. [Epub ahead of print]

PMID:
28874847
5.

WGA-based lectin affinity gel electrophoresis: A novel method for the detection of O-GlcNAc-modified proteins.

Kubota Y, Fujioka K, Takekawa M.

PLoS One. 2017 Jul 7;12(7):e0180714. doi: 10.1371/journal.pone.0180714. eCollection 2017.

6.

Temperature dependence of nitrogen removal activity by anammox bacteria enriched at low temperatures.

Park G, Takekawa M, Soda S, Ike M, Furukawa K.

J Biosci Bioeng. 2017 Apr;123(4):505-511. doi: 10.1016/j.jbiosc.2016.11.009. Epub 2016 Dec 14.

PMID:
27986403
7.

Detection and Functional Analysis of SUMO-Modified MEK.

Kubota Y, Takekawa M.

Methods Mol Biol. 2017;1487:99-111.

PMID:
27924561
8.

A Phos-tag SDS-PAGE method that effectively uses phosphoproteomic data for profiling the phosphorylation dynamics of MEK1.

Kinoshita E, Kinoshita-Kikuta E, Kubota Y, Takekawa M, Koike T.

Proteomics. 2016 Jul;16(13):1825-36. doi: 10.1002/pmic.201500494. Epub 2016 Jun 8.

PMID:
27169363
9.

Genomic Loss of DUSP4 Contributes to the Progression of Intraepithelial Neoplasm of Pancreas to Invasive Carcinoma.

Hijiya N, Tsukamoto Y, Nakada C, Tung Nguyen L, Kai T, Matsuura K, Shibata K, Inomata M, Uchida T, Tokunaga A, Amada K, Shirao K, Yamada Y, Mori H, Takeuchi I, Seto M, Aoki M, Takekawa M, Moriyama M.

Cancer Res. 2016 May 1;76(9):2612-25. doi: 10.1158/0008-5472.CAN-15-1846. Epub 2016 Mar 3.

10.

TIA1 oxidation inhibits stress granule assembly and sensitizes cells to stress-induced apoptosis.

Arimoto-Matsuzaki K, Saito H, Takekawa M.

Nat Commun. 2016 Jan 7;7:10252. doi: 10.1038/ncomms10252.

11.

Association between Chronic Periodontal Disease and Lower Urinary Tract Symptoms in Both Sexes.

Matsumoto S, Matsuda M, Takekawa M, Okada M, Hashizume K, Wada N, Hori J, Kita M, Iwata T, Kakizaki H.

Low Urin Tract Symptoms. 2015 Jan;7(1):17-21. doi: 10.1111/luts.12042. Epub 2013 Oct 27.

PMID:
26663646
12.

Oscillation of p38 activity controls efficient pro-inflammatory gene expression.

Tomida T, Takekawa M, Saito H.

Nat Commun. 2015 Sep 24;6:8350. doi: 10.1038/ncomms9350.

13.

Spatio-temporal Dynamics and Mechanisms of Stress Granule Assembly.

Ohshima D, Arimoto-Matsuzaki K, Tomida T, Takekawa M, Ichikawa K.

PLoS Comput Biol. 2015 Jun 26;11(6):e1004326. doi: 10.1371/journal.pcbi.1004326. eCollection 2015 Jun.

14.

MCRIP1, an ERK substrate, mediates ERK-induced gene silencing during epithelial-mesenchymal transition by regulating the co-repressor CtBP.

Ichikawa K, Kubota Y, Nakamura T, Weng JS, Tomida T, Saito H, Takekawa M.

Mol Cell. 2015 Apr 2;58(1):35-46. doi: 10.1016/j.molcel.2015.01.023. Epub 2015 Feb 26.

15.

Structures of CYLD USP with Met1- or Lys63-linked diubiquitin reveal mechanisms for dual specificity.

Sato Y, Goto E, Shibata Y, Kubota Y, Yamagata A, Goto-Ito S, Kubota K, Inoue J, Takekawa M, Tokunaga F, Fukai S.

Nat Struct Mol Biol. 2015 Mar;22(3):222-9. doi: 10.1038/nsmb.2970. Epub 2015 Feb 16.

PMID:
25686088
16.

[Centrosome integrity under stress is maintained by a network of PLK4, p53 and SAPK pathways].

Takekawa M.

Seikagaku. 2014 Oct;86(5):666-70. Review. Japanese. No abstract available.

PMID:
25509335
17.

Simultaneous anammox and denitrification (SAD) process in sequencing batch reactors.

Takekawa M, Park G, Soda S, Ike M.

Bioresour Technol. 2014 Dec;174:159-66. doi: 10.1016/j.biortech.2014.10.021. Epub 2014 Oct 23.

PMID:
25463795
18.

Association of ED with chronic periodontal disease.

Matsumoto S, Matsuda M, Takekawa M, Okada M, Hashizume K, Wada N, Hori J, Tamaki G, Kita M, Iwata T, Kakizaki H.

Int J Impot Res. 2014 Jan;26(1):13-5. doi: 10.1038/ijir.2013.30. Epub 2013 Jul 4.

PMID:
23823216
19.

SAPK pathways and p53 cooperatively regulate PLK4 activity and centrosome integrity under stress.

Nakamura T, Saito H, Takekawa M.

Nat Commun. 2013;4:1775. doi: 10.1038/ncomms2752.

PMID:
23653187
20.

[Targeting the stress-responsive JNK/p38-AP1 pathway for therapeutic intervention].

Nakamura T, Takekawa M.

Nihon Rinsho. 2012 Nov;70 Suppl 8:218-24. Japanese. No abstract available.

PMID:
23513840
21.

The temporal pattern of stimulation determines the extent and duration of MAPK activation in a Caenorhabditis elegans sensory neuron.

Tomida T, Oda S, Takekawa M, Iino Y, Saito H.

Sci Signal. 2012 Oct 16;5(246):ra76. doi: 10.1126/scisignal.2002983.

22.

Mitochondria take up Ca2+ in two steps dependently on store-operated Ca2+ entry in mast cells.

Takekawa M, Furuno T, Hirashima N, Nakanishi M.

Biol Pharm Bull. 2012;35(8):1354-60.

23.

Diels-Alder derivatization for sensitive detection and characterization of conjugated linoleic acids using LC/ESI-MS/MS.

Higashi T, Takekawa M, Min JZ, Toyo'oka T.

Anal Bioanal Chem. 2012 Apr;403(2):495-502. doi: 10.1007/s00216-012-5819-8. Epub 2012 Feb 26.

PMID:
22367242
24.

Receptor for activated protein kinase C: requirement for efficient microRNA function and reduced expression in hepatocellular carcinoma.

Otsuka M, Takata A, Yoshikawa T, Kojima K, Kishikawa T, Shibata C, Takekawa M, Yoshida H, Omata M, Koike K.

PLoS One. 2011;6(9):e24359. doi: 10.1371/journal.pone.0024359. Epub 2011 Sep 15.

25.

Regulation of stress-activated MAP kinase pathways during cell fate decisions.

Takekawa M, Kubota Y, Nakamura T, Ichikawa K.

Nagoya J Med Sci. 2011 Feb;73(1-2):1-14. Review.

PMID:
21614932
26.

Oncogenic Ras abrogates MEK SUMOylation that suppresses the ERK pathway and cell transformation.

Kubota Y, O'Grady P, Saito H, Takekawa M.

Nat Cell Biol. 2011 Mar;13(3):282-91. doi: 10.1038/ncb2169. Epub 2011 Feb 20.

PMID:
21336309
27.

Stimulus-specific distinctions in spatial and temporal dynamics of stress-activated protein kinase kinase kinases revealed by a fluorescence resonance energy transfer biosensor.

Tomida T, Takekawa M, O'Grady P, Saito H.

Mol Cell Biol. 2009 Nov;29(22):6117-27. doi: 10.1128/MCB.00571-09. Epub 2009 Sep 8.

28.

Distribution of ethenzamide and other ingredients on granule surfaces studied by Raman microspectroscopy and mapping.

Fujimaki Y, Matsubara T, Sakamoto T, Sasakura D, Miura T, Takekawa M, Hiyama Y.

Pharmazie. 2009 May;64(5):316-22.

PMID:
19530442
29.

Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways.

Arimoto K, Fukuda H, Imajoh-Ohmi S, Saito H, Takekawa M.

Nat Cell Biol. 2008 Nov;10(11):1324-32. doi: 10.1038/ncb1791. Epub 2008 Oct 5.

PMID:
18836437
30.
31.
32.

An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathway.

Nakajima A, Komazawa-Sakon S, Takekawa M, Sasazuki T, Yeh WC, Yagita H, Okumura K, Nakano H.

EMBO J. 2006 Nov 29;25(23):5549-59. Epub 2006 Nov 16.

33.

Ultrafast photosynthetic reduction of elemental sulfur by Au nanoparticle-loaded TiO2.

Kiyonaga T, Mitsui T, Torikoshi M, Takekawa M, Soejima T, Tada H.

J Phys Chem B. 2006 Jun 8;110(22):10771-8.

PMID:
16771325
34.

Regulation of the antioncogenic Chk2 kinase by the oncogenic Wip1 phosphatase.

Fujimoto H, Onishi N, Kato N, Takekawa M, Xu XZ, Kosugi A, Kondo T, Imamura M, Oishi I, Yoda A, Minami Y.

Cell Death Differ. 2006 Jul;13(7):1170-80. Epub 2005 Nov 25.

35.
36.

Characterization of a novel low-molecular-mass dual-specificity phosphatase-3 (LDP-3) that enhances activation of JNK and p38.

Takagaki K, Satoh T, Tanuma N, Masuda K, Takekawa M, Shima H, Kikuchi K.

Biochem J. 2004 Nov 1;383(Pt. 3):447-55.

37.

GADD45beta/GADD45gamma and MEKK4 comprise a genetic pathway mediating STAT4-independent IFNgamma production in T cells.

Chi H, Lu B, Takekawa M, Davis RJ, Flavell RA.

EMBO J. 2004 Apr 7;23(7):1576-86. Epub 2004 Mar 25.

38.

NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death.

Sakon S, Xue X, Takekawa M, Sasazuki T, Okazaki T, Kojima Y, Piao JH, Yagita H, Okumura K, Doi T, Nakano H.

EMBO J. 2003 Aug 1;22(15):3898-909.

39.
40.

Angiogenesis after sintered bone implantation in rat parietal bone.

Ohtsubo S, Matsuda M, Takekawa M.

Histol Histopathol. 2003 Jan;18(1):153-63. doi: 10.14670/HH-18.153.

PMID:
12507295
41.

Analysis of gene expression during maturation of immature dendritic cells derived from peripheral blood monocytes.

Matsunaga T, Ishida T, Takekawa M, Nishimura S, Adachi M, Imai K.

Scand J Immunol. 2002 Dec;56(6):593-601.

42.

Smad-dependent GADD45beta expression mediates delayed activation of p38 MAP kinase by TGF-beta.

Takekawa M, Tatebayashi K, Itoh F, Adachi M, Imai K, Saito H.

EMBO J. 2002 Dec 2;21(23):6473-82.

43.

Usage of tautomycetin, a novel inhibitor of protein phosphatase 1 (PP1), reveals that PP1 is a positive regulator of Raf-1 in vivo.

Mitsuhashi S, Shima H, Tanuma N, Matsuura N, Takekawa M, Urano T, Kataoka T, Ubukata M, Kikuchi K.

J Biol Chem. 2003 Jan 3;278(1):82-8. Epub 2002 Oct 8.

44.

Nuclear export of glucocorticoid receptor is enhanced by c-Jun N-terminal kinase-mediated phosphorylation.

Itoh M, Adachi M, Yasui H, Takekawa M, Tanaka H, Imai K.

Mol Endocrinol. 2002 Oct;16(10):2382-92.

PMID:
12351702
45.

[Stress-responsive MAP kinases].

Takekawa M, Tatebayashi K, Saito H.

Tanpakushitsu Kakusan Koso. 2002 Sep;47(11):1379-89. Review. Japanese. No abstract available.

PMID:
12229205
46.

A novel low-molecular-mass dual-specificity phosphatase, LDP-2, with a naturally occurring substitution that affects substrate specificity.

Nakamura K, Tanoue K, Satoh T, Takekawa M, Watanabe M, Shima H, Kikuchi K.

J Biochem. 2002 Sep;132(3):463-70.

47.

MEK/ERK pathway protects ionizing radiation-induced loss of mitochondrial membrane potential and cell death in lymphocytic leukemia cells.

Shonai T, Adachi M, Sakata K, Takekawa M, Endo T, Imai K, Hareyama M.

Cell Death Differ. 2002 Sep;9(9):963-71.

48.

Regulation of MTK1/MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding.

Mita H, Tsutsui J, Takekawa M, Witten EA, Saito H.

Mol Cell Biol. 2002 Jul;22(13):4544-55.

49.

Decreased production of interleukin-12 and type 2 immune responses are marked in cachectic patients with colorectal and gastric cancer.

Shibata M, Nezu T, Kanou H, Abe H, Takekawa M, Fukuzawa M.

J Clin Gastroenterol. 2002 Apr;34(4):416-20.

PMID:
11907352
50.

Immunomodulatory effects of low dose cis-Diaminedichloroplatinum (cisplatin) combined with UFT and PSK in patients with advanced colorectal cancer.

Shibata M, Nezu T, Kanou H, Nagata Y, Kimura T, Takekawa M, Ando K, Fukuzawa M.

Cancer Invest. 2002;20(2):166-73.

PMID:
11901535

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