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Items: 1 to 50 of 1273

1.

Urinary Activin A is a novel biomarker reflecting renal inflammation and tubular damage in ANCA-associated vasculitis.

Takei Y, Takahashi S, Nakasatomi M, Sakairi T, Ikeuchi H, Kaneko Y, Hiromura K, Nojima Y, Maeshima A.

PLoS One. 2019 Oct 15;14(10):e0223703. doi: 10.1371/journal.pone.0223703. eCollection 2019.

2.

Reduction in HPV16/18 prevalence among young women with high-grade cervical lesions following the Japanese HPV vaccination program.

Matsumoto K, Yaegashi N, Iwata T, Yamamoto K, Aoki Y, Okadome M, Ushijima K, Kamiura S, Takehara K, Horie K, Tasaka N, Sonoda K, Takei Y, Aoki Y, Konnai K, Katabuchi H, Nakamura K, Ishikawa M, Watari H, Yoshida H, Matsumura N, Nakai H, Shigeta S, Takahashi F, Noda K, Yoshikawa H; MINT Study Group.

Cancer Sci. 2019 Oct 9. doi: 10.1111/cas.14212. [Epub ahead of print]

3.

Hemorrhagic Colitis Induced by Second-line Helicobacter pylori Eradication.

Hamada Y, Tanaka K, Yamada R, Takei Y.

Intern Med. 2019 Sep 3. doi: 10.2169/internalmedicine.3565-19. [Epub ahead of print] No abstract available.

4.

Fabrication of Simultaneously Implementing "Wired Face-Up and Face-Down Ultrathin Piezoresistive Si Chips" on a Film Substrate by Screen-Offset Printing.

Takei Y, Nomura KI, Horii Y, Zymelka D, Ushijima H, Kobayashi T.

Micromachines (Basel). 2019 Aug 26;10(9). pii: E563. doi: 10.3390/mi10090563.

5.

Protective Role of Matrix Metalloproteinase-2 in Allergic Bronchial Asthma.

Takahashi Y, Kobayashi T, D'Alessandro-Gabazza CN, Toda M, Fujiwara K, Okano T, Fujimoto H, Asayama K, Takeshita A, Yasuma T, Nishihama K, Inoue R, Qin L, Takei Y, Taguchi O, Gabazza EC.

Front Immunol. 2019 Aug 2;10:1795. doi: 10.3389/fimmu.2019.01795. eCollection 2019.

6.

Angiographic Findings in Patients with Hepatocellular Carcinoma Previously Treated Using Proton Beam Therapy.

Takahashi H, Mori K, Sekino Y, Okumura T, Hiyama T, Fukuda K, Hasegawa N, Sakai M, Kikuchi S, Takei Y, Iizumi T, Sakurai H, Minami M.

J Oncol. 2019 Jul 4;2019:3580379. doi: 10.1155/2019/3580379. eCollection 2019.

7.

Increase in circulating ACE-positive endothelial microparticles during acute lung injury.

Takei Y, Yamada M, Saito K, Kameyama Y, Sugiura H, Makiguchi T, Fujino N, Koarai A, Toyama H, Saito K, Ejima Y, Kawazoe Y, Kudo D, Kushimoto S, Yamauchi M, Ichinose M.

Eur Respir J. 2019 Oct 17;54(4). pii: 1801188. doi: 10.1183/13993003.01188-2018. Print 2019 Oct.

PMID:
31320458
8.

Cell-free and Concentrated Ascites Reinfusion Therapy for Refractory Ascites in Cirrhosis in Post-marketing Surveillance and the Role of Tolvaptan.

Iwasa M, Ishihara T, Kato M, Isoai A, Kobayashi R, Torii N, Soneda N, Takei Y.

Intern Med. 2019 Jul 10. doi: 10.2169/internalmedicine.3091-19. [Epub ahead of print]

9.

Changes in acetyl-CoA mediate Sik3-induced maturation of chondrocytes in endochondral bone formation.

Kosai A, Horike N, Takei Y, Yamashita A, Fujita K, Kamatani T, Tsumaki N.

Biochem Biophys Res Commun. 2019 Sep 3;516(4):1097-1102. doi: 10.1016/j.bbrc.2019.06.139. Epub 2019 Jul 5.

10.

Inhibition of epidermal growth factor receptor stimulates prolactin expression in primary culture of the mouse pituitary gland.

Nogami H, Koshida R, Omori H, Shibata M, Harigaya T, Takei Y.

J Neuroendocrinol. 2019 Aug;31(8):e12764. doi: 10.1111/jne.12764. Epub 2019 Jul 8.

PMID:
31251840
11.

Preparatory Mechanisms for Salinity Tolerance in Two Congeneric Anuran Species Inhabiting Distinct Osmotic Habitats.

Haramura T, Ikegami T, Wong MKS, Takei Y.

Zoolog Sci. 2019 Jun 1;36(3):215-222. doi: 10.2108/zs180091.

PMID:
31251490
12.

Hypozincemia is associated with human hepatocarcinogenesis in hepatitis C virus-related liver cirrhosis.

Shigefuku R, Iwasa M, Katayama K, Eguchi A, Kawaguchi T, Shiraishi K, Ito T, Suzuki K, Koreeda C, Ohtake T, Tokumoto Y, Endo R, Kawamura N, Shiraki M, Habu D, Sakai H, Kato A, Nishiguchi S, Moriwaki H, Suzuki K, Takei Y.

Hepatol Res. 2019 Jun 25. doi: 10.1111/hepr.13388. [Epub ahead of print]

PMID:
31240767
13.

Endoscopic submucosal dissection-induced incarcerated diaphragmatic hernia.

Hamada Y, Tanaka K, Katsurahara M, Nakamura M, Takei Y.

Gastrointest Endosc. 2019 Nov;90(5):852-854. doi: 10.1016/j.gie.2019.06.017. Epub 2019 Jun 20. No abstract available.

PMID:
31228429
14.

Infiltrating CCR2+ monocytes and their progenies, fibrocytes, contribute to colon fibrosis by inhibiting collagen degradation through the production of TIMP-1.

Kuroda N, Masuya M, Tawara I, Tsuboi J, Yoneda M, Nishikawa K, Kageyama Y, Hachiya K, Ohishi K, Miwa H, Yamada R, Hamada Y, Tanaka K, Kato T, Takei Y, Katayama N.

Sci Rep. 2019 Jun 12;9(1):8568. doi: 10.1038/s41598-019-45012-6.

15.

Elevated maternal retinoic acid-related orphan receptor-γt enhances the effect of polyinosinic-polycytidylic acid in inducing fetal loss.

Tome S, Sasaki T, Takahashi S, Takei Y.

Exp Anim. 2019 Jun 10. doi: 10.1538/expanim.19-0038. [Epub ahead of print]

16.

Molecular mechanisms for intestinal HCO3 - secretion and its regulation by guanylin in seawater-acclimated eels.

Takei Y, Wong MKS, Ando M.

J Exp Biol. 2019 Jul 5;222(Pt 13). pii: jeb203539. doi: 10.1242/jeb.203539.

PMID:
31171602
17.

Serum Liver-Type Fatty Acid-Binding Protein Is a Possible Prognostic Factor in Human Chronic Liver Diseases From Chronic Hepatitis to Liver Cirrhosis and Hepatocellular Carcinoma.

Eguchi A, Hasegawa H, Iwasa M, Tamai Y, Ohata K, Oikawa T, Sugaya T, Takei Y.

Hepatol Commun. 2019 Apr 2;3(6):825-837. doi: 10.1002/hep4.1350. eCollection 2019 Jun.

18.

Selective Cytotoxicity of Staphylococcal α-Hemolysin (α-Toxin) against Human Leukocyte Populations.

Tsuiji M, Shiohara K, Takei Y, Shinohara Y, Nemoto S, Yamaguchi S, Kanto M, Itoh S, Oku T, Miyashita M, Seyama Y, Kurihara M, Tsuji T.

Biol Pharm Bull. 2019;42(6):982-988. doi: 10.1248/bpb.b18-01024.

19.

A phase II randomized controlled study of pegylated liposomal doxorubicin and carboplatin vs. gemcitabine and carboplatin for platinum-sensitive recurrent ovarian cancer (GOTIC003/intergroup study).

Fujiwara H, Ushijima K, Nagao S, Takei Y, Shimada M, Takano M, Yoshino K, Kawano Y, Hirashima Y, Nagase S, Nishio S, Nishikawa T, Ito K, Shoji T, Kimura E, Takano T, Sugiyama T, Kigawa J, Fujiwara K, Suzuki M.

Int J Clin Oncol. 2019 Oct;24(10):1284-1291. doi: 10.1007/s10147-019-01471-5. Epub 2019 May 24.

PMID:
31127479
20.

Management of the late effects of disconnected pancreatic duct syndrome: A case report.

Yamada R, Umeda Y, Shiono Y, Okuse H, Kuroda N, Tsuboi J, Inoue H, Hamada Y, Tanaka K, Horiki N, Takei Y.

World J Clin Cases. 2019 May 6;7(9):1053-1059. doi: 10.12998/wjcc.v7.i9.1053.

21.

siRNA-Based Drug Targeting Human Bcl-xL Against Cancers.

Takei Y.

Methods Mol Biol. 2019;1974:31-40. doi: 10.1007/978-1-4939-9220-1_3.

PMID:
31098993
22.

Receptor tyrosine kinase activation induces free fatty acid 4 receptor phosphorylation, β-arrestin interaction, and internalization.

Villegas-Comonfort S, Guzmán-Silva A, Romero-Ávila MT, Takei Y, Tsujimoto G, Hirasawa A, García-Sáinz JA.

Eur J Pharmacol. 2019 Jul 15;855:267-275. doi: 10.1016/j.ejphar.2019.05.018. Epub 2019 May 10.

PMID:
31078517
23.

A substitution in the pre-S1 promoter region is associated with the viral regulation of hepatitis B virus.

Ogura S, Tameda M, Sugimoto K, Ikejiri M, Usui M, Ito M, Takei Y.

Virol J. 2019 May 2;16(1):59. doi: 10.1186/s12985-019-1169-x.

24.

Changing clinical and molecular characteristics of hepatitis E virus infection in Mie Prefecture, Japan: Disappearance of indigenous subtype 3e strains.

Nakano T, Okano H, Takahashi M, Nagashima S, Shiraki K, Oya Y, Inoue H, Ohmori S, Tsukimoto M, Ishida S, Fujimoto S, Kobayashi M, Yamawaki M, Kumagai M, Ninomiya J, Maegawa T, Kojima Y, Araki J, Hamaoka S, Horiike S, Yoshimura H, Takeuchi K, Itoh K, Akachi S, Uraki S, Yamamoto N, Ogura S, Sugimoto K, Yoshikawa K, Hasegawa H, Iwasa M, Takei Y, Okamoto H.

Hepatol Res. 2019 Sep;49(9):1003-1014. doi: 10.1111/hepr.13357. Epub 2019 Jun 7.

PMID:
31026368
25.

Urolithiasis with overdiagnosed nutcracker syndrome in a pediatric patient.

Kanai H, Sato H, Takei Y.

Pediatr Int. 2019 Apr;61(4):425-427. doi: 10.1111/ped.13796. Epub 2019 Apr 14. No abstract available.

PMID:
30983071
26.

Relationship between Contact Pressure and Motion Artifacts in ECG Measurement with Electrostatic Flocked Electrodes Fabricated on Textile.

Takeshita T, Yoshida M, Takei Y, Ouchi A, Hinoki A, Uchida H, Kobayashi T.

Sci Rep. 2019 Apr 11;9(1):5897. doi: 10.1038/s41598-019-42027-x.

27.

Brain functional alterations observed 4-weekly in major depressive disorder following antidepressant treatment.

Yamagata B, Yamanaka K, Takei Y, Hotta S, Hirano J, Tabuchi H, Mimura M.

J Affect Disord. 2019 Jun 1;252:25-31. doi: 10.1016/j.jad.2019.04.001. Epub 2019 Apr 3.

PMID:
30959413
28.

Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH.

Eng CL, Lawson M, Zhu Q, Dries R, Koulena N, Takei Y, Yun J, Cronin C, Karp C, Yuan GC, Cai L.

Nature. 2019 Apr;568(7751):235-239. doi: 10.1038/s41586-019-1049-y. Epub 2019 Mar 25.

29.

Excessive salt intake increases peritoneal solute transport rate via local tonicity-responsive enhancer binding protein in subtotal nephrectomized mice.

Sun T, Sakata F, Ishii T, Tawada M, Suzuki Y, Kinashi H, Katsuno T, Takei Y, Maruyama S, Mizuno M, Ito Y.

Nephrol Dial Transplant. 2019 Mar 20. pii: gfz045. doi: 10.1093/ndt/gfz045. [Epub ahead of print]

PMID:
30897196
30.

The surface composition of asteroid 162173 Ryugu from Hayabusa2 near-infrared spectroscopy.

Kitazato K, Milliken RE, Iwata T, Abe M, Ohtake M, Matsuura S, Arai T, Nakauchi Y, Nakamura T, Matsuoka M, Senshu H, Hirata N, Hiroi T, Pilorget C, Brunetto R, Poulet F, Riu L, Bibring JP, Takir D, Domingue DL, Vilas F, Barucci MA, Perna D, Palomba E, Galiano A, Tsumura K, Osawa T, Komatsu M, Nakato A, Arai T, Takato N, Matsunaga T, Takagi Y, Matsumoto K, Kouyama T, Yokota Y, Tatsumi E, Sakatani N, Yamamoto Y, Okada T, Sugita S, Honda R, Morota T, Kameda S, Sawada H, Honda C, Yamada M, Suzuki H, Yoshioka K, Hayakawa M, Ogawa K, Cho Y, Shirai K, Shimaki Y, Hirata N, Yamaguchi A, Ogawa N, Terui F, Yamaguchi T, Takei Y, Saiki T, Nakazawa S, Tanaka S, Yoshikawa M, Watanabe S, Tsuda Y.

Science. 2019 Apr 19;364(6437):272-275. doi: 10.1126/science.aav7432. Epub 2019 Mar 19.

PMID:
30890589
31.

Hayabusa2 arrives at the carbonaceous asteroid 162173 Ryugu-A spinning top-shaped rubble pile.

Watanabe S, Hirabayashi M, Hirata N, Hirata N, Noguchi R, Shimaki Y, Ikeda H, Tatsumi E, Yoshikawa M, Kikuchi S, Yabuta H, Nakamura T, Tachibana S, Ishihara Y, Morota T, Kitazato K, Sakatani N, Matsumoto K, Wada K, Senshu H, Honda C, Michikami T, Takeuchi H, Kouyama T, Honda R, Kameda S, Fuse T, Miyamoto H, Komatsu G, Sugita S, Okada T, Namiki N, Arakawa M, Ishiguro M, Abe M, Gaskell R, Palmer E, Barnouin OS, Michel P, French AS, McMahon JW, Scheeres DJ, Abell PA, Yamamoto Y, Tanaka S, Shirai K, Matsuoka M, Yamada M, Yokota Y, Suzuki H, Yoshioka K, Cho Y, Tanaka S, Nishikawa N, Sugiyama T, Kikuchi H, Hemmi R, Yamaguchi T, Ogawa N, Ono G, Mimasu Y, Yoshikawa K, Takahashi T, Takei Y, Fujii A, Hirose C, Iwata T, Hayakawa M, Hosoda S, Mori O, Sawada H, Shimada T, Soldini S, Yano H, Tsukizaki R, Ozaki M, Iijima Y, Ogawa K, Fujimoto M, Ho TM, Moussi A, Jaumann R, Bibring JP, Krause C, Terui F, Saiki T, Nakazawa S, Tsuda Y.

Science. 2019 Apr 19;364(6437):268-272. doi: 10.1126/science.aav8032. Epub 2019 Mar 19.

PMID:
30890588
32.

The geomorphology, color, and thermal properties of Ryugu: Implications for parent-body processes.

Sugita S, Honda R, Morota T, Kameda S, Sawada H, Tatsumi E, Yamada M, Honda C, Yokota Y, Kouyama T, Sakatani N, Ogawa K, Suzuki H, Okada T, Namiki N, Tanaka S, Iijima Y, Yoshioka K, Hayakawa M, Cho Y, Matsuoka M, Hirata N, Hirata N, Miyamoto H, Domingue D, Hirabayashi M, Nakamura T, Hiroi T, Michikami T, Michel P, Ballouz RL, Barnouin OS, Ernst CM, Schröder SE, Kikuchi H, Hemmi R, Komatsu G, Fukuhara T, Taguchi M, Arai T, Senshu H, Demura H, Ogawa Y, Shimaki Y, Sekiguchi T, Müller TG, Hagermann A, Mizuno T, Noda H, Matsumoto K, Yamada R, Ishihara Y, Ikeda H, Araki H, Yamamoto K, Abe S, Yoshida F, Higuchi A, Sasaki S, Oshigami S, Tsuruta S, Asari K, Tazawa S, Shizugami M, Kimura J, Otsubo T, Yabuta H, Hasegawa S, Ishiguro M, Tachibana S, Palmer E, Gaskell R, Le Corre L, Jaumann R, Otto K, Schmitz N, Abell PA, Barucci MA, Zolensky ME, Vilas F, Thuillet F, Sugimoto C, Takaki N, Suzuki Y, Kamiyoshihara H, Okada M, Nagata K, Fujimoto M, Yoshikawa M, Yamamoto Y, Shirai K, Noguchi R, Ogawa N, Terui F, Kikuchi S, Yamaguchi T, Oki Y, Takao Y, Takeuchi H, Ono G, Mimasu Y, Yoshikawa K, Takahashi T, Takei Y, Fujii A, Hirose C, Nakazawa S, Hosoda S, Mori O, Shimada T, Soldini S, Iwata T, Abe M, Yano H, Tsukizaki R, Ozaki M, Nishiyama K, Saiki T, Watanabe S, Tsuda Y.

Science. 2019 Apr 19;364(6437):252. doi: 10.1126/science.aaw0422. Epub 2019 Mar 19.

PMID:
30890587
33.

Perinatal outcome of pregnancy after adenomyomectomy: summary of 10 cases with a brief literature review.

Sugiyama M, Takahashi H, Baba Y, Taneichi A, Suzuki H, Usui R, Takei Y, Ohkuchi A, Fujiwara H, Matsubara S.

J Matern Fetal Neonatal Med. 2019 Mar 28:1-5. doi: 10.1080/14767058.2019.1597845. [Epub ahead of print]

PMID:
30889999
34.

Polygon-like luminal configuration captured by intracoronary optical frequency domain imaging of a spontaneous coronary spasm in an ST-elevation myocardial infarction patient.

Takei Y, Mori H, Sone H, Tashiro K, Sasai M, Sato T, Suzuki H.

Coron Artery Dis. 2019 Jun;30(4):314-315. doi: 10.1097/MCA.0000000000000728. No abstract available.

PMID:
30883429
35.

Modified hysterectomy for placenta increta and percreta: modifications of what?

Matsubara S, Takahashi H, Takei Y.

Arch Gynecol Obstet. 2019 Jun;299(6):1751-1752. doi: 10.1007/s00404-019-05114-y. Epub 2019 Mar 11. No abstract available.

PMID:
30859298
36.

Circulating Extracellular Vesicles and Their miR "Barcode" Differentiate Alcohol Drinkers With Liver Injury and Those Without Liver Injury in Severe Trauma Patients.

Eguchi A, Franz N, Kobayashi Y, Iwasa M, Wagner N, Hildebrand F, Takei Y, Marzi I, Relja B.

Front Med (Lausanne). 2019 Feb 25;6:30. doi: 10.3389/fmed.2019.00030. eCollection 2019.

37.

Predictors for pathological parametrial invasion in clinical stage IIB cervical cancer.

Matsuo K, Shimada M, Nakamura K, Takei Y, Ushijima K, Sumi T, Ohara T, Yahata H, Mikami M, Sugiyama T.

Eur J Surg Oncol. 2019 Aug;45(8):1417-1424. doi: 10.1016/j.ejso.2019.02.019. Epub 2019 Feb 18.

PMID:
30846298
38.

Development of electroforming process for soft x-ray ellipsoidal mirror.

Kume T, Takei Y, Egawa S, Motoyama H, Takeo Y, Yamaguchi G, Mimura H.

Rev Sci Instrum. 2019 Feb;90(2):021718. doi: 10.1063/1.5057432.

PMID:
30831680
39.

[AOCMP2018].

Takei Y.

Igaku Butsuri. 2019;38(4):182-183. doi: 10.11323/jjmp.38.4_182. Japanese. No abstract available.

PMID:
30828053
Free Article
40.

Age-dependent decline in neurogenesis of the hippocampus and extracellular nucleotides.

Takei Y.

Hum Cell. 2019 Apr;32(2):88-94. doi: 10.1007/s13577-019-00241-9. Epub 2019 Feb 7. Review.

PMID:
30730038
41.

Lung-diffusing capacity for carbon monoxide predicts early complications after cardiac surgery.

Kuwata T, Shibasaki I, Ogata K, Ogawa H, Takei Y, Seki M, Kiriya Y, Fukuda H.

Surg Today. 2019 Jul;49(7):571-579. doi: 10.1007/s00595-019-1770-z. Epub 2019 Jan 31.

42.

Neointimal erosion resulting in very-late stent thrombosis.

Mori H, Sone H, Takei Y, Tashiro K, Sasai M, Maeda A, Sato T, Suzuki H.

Coron Artery Dis. 2019 Jun;30(4):312-313. doi: 10.1097/MCA.0000000000000717. No abstract available.

PMID:
30694821
43.

Gastrointestinal: A case of small bowel obstruction caused by a bezoar, preoperatively found by double-balloon enteroscopy.

Katsurahara M, Yamada R, Inoue H, Hamada Y, Tanaka K, Horiki N, Takei Y.

J Gastroenterol Hepatol. 2019 Jun;34(6):962. doi: 10.1111/jgh.14589. Epub 2019 Jan 28. Review. No abstract available.

PMID:
30693556
44.

Hysterectomy: All obstetrician-gynecologists should learn to perform it.

Matsubara S, Takahashi H, Takei Y, Lefor AK, Fujiwara H.

Acta Obstet Gynecol Scand. 2019 Jun;98(6):813. doi: 10.1111/aogs.13539. Epub 2019 Feb 3. No abstract available.

PMID:
30661252
45.

Highly aggressive plasmablastic neoplasms in patients with rheumatoid arthritis treated with methotrexate.

Tabata R, Tabata C, Uesugi H, Takei Y.

Int Immunopharmacol. 2019 Mar;68:213-217. doi: 10.1016/j.intimp.2019.01.014. Epub 2019 Jan 15.

PMID:
30658314
46.

Modified Total Arch Debranching TEVAR with Aberrant Left Vertebral Artery.

Takei Y, Hori T, Kanno Y, Shibasaki I, Fukuda H.

Ann Vasc Dis. 2018 Dec 25;11(4):545-548. doi: 10.3400/avd.cr.18-00043.

47.

New criteria for the omission of lymphadenectomy in endometrioid carcinoma.

Matsushita C, Fujiwara H, Takei Y, Saga Y, Machida S, Taneichi A, Takahashi S, Yoshiba T, Koyanagi T, Takahashi Y, Morisawa H, Suzuki M.

Int J Gynecol Cancer. 2019 Mar;29(3):541-546. doi: 10.1136/ijgc-2018-000044. Epub 2019 Jan 10.

PMID:
30630888
48.

Simultaneous measurement of patient dose and distribution of indoor scattered radiation during digital breast tomosynthesis.

Nakamura T, Suzuki S, Takei Y, Kobayashi I, Pongnapang N, Kato K.

Radiography (Lond). 2019 Feb;25(1):72-76. doi: 10.1016/j.radi.2018.10.006. Epub 2018 Nov 15.

PMID:
30599834
49.

[Evaluation of Radiation Exposure on Mass Screening Examination for Gastric Cancer Using an Air Kerma-area Product Meter].

Suzuki C, Yamauchi Y, Yamamura D, Takei Y, Suzuki S.

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2018 Dec;74(12):1434-1442. doi: 10.6009/jjrt.2018_JSRT_74.12.1434. Japanese.

50.

Analysis of 307 cases with drug-induced liver injury between 2010 and 2018 in Japan.

Aiso M, Takikawa H, Tsuji K, Kagawa T, Watanabe M, Tanaka A, Sato K, Sakisaka S, Hiasa Y, Takei Y, Ohira H, Ayada M, Hashimoto E, Kaneko S, Ueno Y, Ohmoto K, Takaki A, Torimura T, Matsuzaki Y, Tajiri K, Yoneda M, Ito T, Kato N, Ikejima K, Mochida S, Yasuda H, Sakamoto N.

Hepatol Res. 2019 Jan;49(1):105-110. doi: 10.1111/hepr.13288.

PMID:
30565816

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