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Items: 1 to 50 of 1698

1.

Low incidence of late recurrence in patients with intermediate-risk prostate cancer treated by intensity-modulated radiation therapy plus short-term androgen deprivation therapy.

Aizawa R, Takayama K, Nakamura K, Inoue T, Yamasaki T, Kobayashi T, Akamatsu S, Ogawa O, Mizowaki T.

Int J Clin Oncol. 2019 Dec 9. doi: 10.1007/s10147-019-01596-7. [Epub ahead of print]

PMID:
31820209
2.

Disulfide-driven cyclic peptide synthesis of human endothelin-2 with a solid-supported Npys-Cl.

Taguchi A, Kobayashi K, Cui Y, Takayama K, Taniguchi A, Hayashi Y.

J Org Chem. 2019 Dec 3. doi: 10.1021/acs.joc.9b02362. [Epub ahead of print]

PMID:
31793782
3.

Transnasal Delivery of the Peptide Agonist Specific to Neuromedin-U Receptor 2 to the Brain for the Treatment of Obesity.

Tanaka A, Takayama K, Furubayashi T, Mori K, Takemura Y, Amano M, Maeda C, Inoue D, Kimura S, Kiriyama A, Katsumi H, Miyazato M, Kangawa K, Sakane T, Hayashi Y, Yamamoto A.

Mol Pharm. 2019 Dec 9. doi: 10.1021/acs.molpharmaceut.9b00571. [Epub ahead of print]

PMID:
31765157
4.

Synthesis and structure-activity relationship studies of IgG-binding peptides focused on the C-terminal histidine residue.

Muguruma K, Ito M, Fukuda A, Kishimoto S, Taguchi A, Takayama K, Taniguchi A, Ito Y, Hayashi Y.

Medchemcomm. 2019 Aug 1;10(10):1789-1795. doi: 10.1039/c9md00294d. eCollection 2019 Oct 1.

PMID:
31762965
5.

Proton Beam Therapy for Locally Recurrent Parotid Gland Cancer.

Azami Y, Hayashi Y, Nakamura T, Kimura K, Yamaguchi H, Ono T, Takayama K, Hirose K, Yabuuchi T, Suzuki M, Hatayama Y, Hareyama M, Kikuchi Y, Fuwa N.

Indian J Otolaryngol Head Neck Surg. 2019 Oct;71(Suppl 1):49-54. doi: 10.1007/s12070-016-1008-y. Epub 2016 Jul 9.

PMID:
31741929
6.

RNA-binding protein NONO promotes breast cancer proliferation by post-transcriptional regulation of SKP2 and E2F8.

Iino K, Mitobe Y, Ikeda K, Takayama KI, Suzuki T, Kawabata H, Suzuki Y, Horie-Inoue K, Inoue S.

Cancer Sci. 2019 Nov 16. doi: 10.1111/cas.14240. [Epub ahead of print]

7.

A rare case of pulmonary typical carcinoid with prominent acinic cell differentiation, resembling acinic cell carcinoma.

Watanabe H, Miyagawa-Hayashino A, Imabayashi T, Kishimoto M, Shimomura M, Honda K, Omatsu I, Shimada E, Inoue M, Takayama K, Konishi E.

Pathol Int. 2019 Nov 14. doi: 10.1111/pin.12869. [Epub ahead of print]

PMID:
31724260
8.

Cough related to swallowing in asthma patients.

Kamimura M, Mouri A, Takayama K, Mizutani T, Hamamoto Y, Iikura M, Furihata K.

Asia Pac Allergy. 2019 Oct 14;9(4):e31. doi: 10.5415/apallergy.2019.9.e31. eCollection 2019 Oct.

9.

Identification of Underlying Inflammation in Vogt-Koyanagi-Harada Disease with Sunset Glow Fundus by Multiple Analyses.

Murata T, Sako N, Takayama K, Harimoto K, Kanda K, Herbort CP Jr, Takeuchi M.

J Ophthalmol. 2019 Oct 3;2019:3853794. doi: 10.1155/2019/3853794. eCollection 2019.

10.

[Medicinal Chemistry Focused on Mid-sized Peptides Derived from Biomolecules].

Takayama K.

Yakugaku Zasshi. 2019;139(11):1377-1384. doi: 10.1248/yakushi.19-00149. Japanese.

11.

Prognostic factors of revitrectomy for complications in eyes with proliferative diabetic retinopathy: a retrospective multicentre study.

Takayama K, Someya H, Yokoyama H, Kimura T, Takamura Y, Morioka M, Sameshima S, Ueda T, Ogata N, Kitano S, Tashiro M, Sugimoto M, Kondo M, Sakamoto T, Takeuchi M.

Acta Ophthalmol. 2019 Nov 1. doi: 10.1111/aos.14292. [Epub ahead of print]

PMID:
31674137
12.

Phase II Study on Biweekly Combination Therapy of Gemcitabine plus Carboplatin for the Treatment of Elderly Patients with Advanced Non-Small Cell Lung Cancer.

Takayama K, Ichiki M, Matsumoto T, Ebi N, Akamine S, Tokunaga S, Yamada T, Uchino J, Nakanishi Y.

Oncologist. 2019 Oct 21. pii: theoncologist.2019-0717. doi: 10.1634/theoncologist.2019-0717. [Epub ahead of print]

PMID:
31636145
13.

New Negamycin-Based Potent Readthrough Derivative Effective against TGA-Type Nonsense Mutations.

Hamada K, Omura N, Taguchi A, Baradaran-Heravi A, Kotake M, Arai M, Takayama K, Taniguchi A, Roberge M, Hayashi Y.

ACS Med Chem Lett. 2019 Sep 23;10(10):1450-1456. doi: 10.1021/acsmedchemlett.9b00273. eCollection 2019 Oct 10.

PMID:
31620232
14.

Risk Factors of Neovascular Glaucoma After 25-gauge Vitrectomy for Proliferative Diabetic Retinopathy with Vitreous Hemorrhage: A Retrospective Multicenter Study.

Takayama K, Someya H, Yokoyama H, Takamura Y, Morioka M, Sameshima S, Ueda T, Kitano S, Tashiro M, Sugimoto M, Kondo M, Sakamoto T, Takeuchi M.

Sci Rep. 2019 Oct 16;9(1):14858. doi: 10.1038/s41598-019-51411-6.

15.

Evaluation of the accuracy of acetabular cup orientation using the accelerometer-based portable navigation system.

Hayashi S, Hashimoto S, Takayama K, Matsumoto T, Kamenaga T, Fujishiro T, Hiranaka T, Niikura T, Kuroda R.

J Orthop Sci. 2019 Oct 13. pii: S0949-2658(19)30287-8. doi: 10.1016/j.jos.2019.09.012. [Epub ahead of print]

PMID:
31619323
16.

Influence of Narrow Femoral Implants on Intraoperative Soft Tissue Balance in Posterior-Stabilized Total Knee Arthroplasty.

Ishida K, Shibanuma N, Sasaki H, Takayama K, Kuroda R, Matsumoto T.

J Arthroplasty. 2019 Sep 5. pii: S0883-5403(19)30818-6. doi: 10.1016/j.arth.2019.08.055. [Epub ahead of print]

PMID:
31604592
17.

Delayed Intracranial Parenchymal Changes After Aneurysmal Coil Embolization Procedures for Unruptured Intracranial Aneurysms.

Nakagawa I, Park HS, Kotsugi M, Morisaki Y, Wada T, Aketa S, Takayama K, Fujimoto K, Deguchi J, Kichikawa K, Nakase H.

Oper Neurosurg (Hagerstown). 2019 Oct 4. pii: opz299. doi: 10.1093/ons/opz299. [Epub ahead of print]

PMID:
31584072
18.

The Usefulness of Definitive Screening Design for a Quality by Design Approach as Demonstrated by a Pharmaceutical Study of Orally Disintegrating Tablet.

Takagaki K, Ito T, Arai H, Obata Y, Takayama K, Onuki Y.

Chem Pharm Bull (Tokyo). 2019;67(10):1144-1151. doi: 10.1248/cpb.c19-00553.

19.

[Pharmaceutical Research on Liver Diseases Using iPS Cell and Genome Editing Technologies].

Takayama K.

Yakugaku Zasshi. 2019;139(10):1219-1225. doi: 10.1248/yakushi.19-00138. Japanese.

20.
21.

Safety and efficacy of PD-1/PD-L1 blockade in patients with preexisting antinuclear antibodies.

Sakakida T, Ishikawa T, Chihara Y, Harita S, Uchino J, Tabuchi Y, Komori S, Asai J, Narukawa T, Arai A, Tsunezuka H, Kosuga T, Konishi H, Moriguchi M, Yasuda H, Hongo F, Inoue M, Hirano S, Ukimura O, Itoh Y, Taguchi T, Takayama K.

Clin Transl Oncol. 2019 Oct 1. doi: 10.1007/s12094-019-02214-8. [Epub ahead of print]

PMID:
31576495
22.

Comparing three different anti-PD-L1 antibodies for immunohistochemical evaluation of small cell lung cancer.

Yoshimura A, Yamada T, Miyagawa-Hayashino A, Sonobe Y, Imabayashi T, Yamada T, Okada S, Shimamoto T, Chihara Y, Iwasaku M, Kaneko Y, Uchino J, Inoue M, Konishi E, Takayama K.

Lung Cancer. 2019 Nov;137:108-112. doi: 10.1016/j.lungcan.2019.09.012. Epub 2019 Sep 16.

PMID:
31568887
23.

Rationale and design of a phase II study to evaluate prophylactic treatment of dacomitinib-induced dermatologic adverse events in epidermal growth factor receptor-mutated advanced non-small cell lung cancer (SPIRAL-Daco study).

Iwasaku M, Uchino J, Yamada T, Chihara Y, Shimamoto T, Tamiya N, Kaneko Y, Kiyomi F, Takayama K.

Transl Lung Cancer Res. 2019 Aug;8(4):519-523. doi: 10.21037/tlcr.2019.08.03.

24.

Retrospective analysis of docetaxel in combination with ramucirumab for previously treated non-small cell lung cancer patients.

Yoshimura A, Yamada T, Okuma Y, Kitadai R, Takeda T, Kanematsu T, Goto H, Yoneda H, Harada T, Kubota Y, Yamada T, Date K, Shiotsu S, Nagata K, Chihara Y, Kaneko Y, Uchino J, Nishioka Y, Takayama K.

Transl Lung Cancer Res. 2019 Aug;8(4):450-460. doi: 10.21037/tlcr.2019.08.07.

25.

Proton Beam Therapy Combined with Intra-Arterial Infusion Chemotherapy for Stage IV Adenoid Cystic Carcinoma of the Base of the Tongue.

Takayama K, Kato T, Nakamura T, Azami Y, Ono T, Suzuki M, Takada A, Yamaguchi H, Seto I, Nakasato T, Wada H, Kikuchi Y, Mitsudo K, Fuwa N, Murakami M.

Cancers (Basel). 2019 Sep 22;11(10). pii: E1413. doi: 10.3390/cancers11101413.

26.

Amyloid precursor protein, an androgen-regulated gene, is targeted by RNA-binding protein PSF/SFPQ in neuronal cells.

Takayama KI, Fujiwara K, Inoue S.

Genes Cells. 2019 Nov;24(11):719-730. doi: 10.1111/gtc.12721. Epub 2019 Oct 15.

PMID:
31541592
27.

Kinetics-Based Structural Requirements of Human Immunoglobulin G Binding Peptides.

Muguruma K, Fujita K, Fukuda A, Kishimoto S, Sakamoto S, Arima R, Ito M, Kawasaki M, Nakano S, Ito S, Shimizu K, Taguchi A, Takayama K, Taniguchi A, Ito Y, Hayashi Y.

ACS Omega. 2019 Aug 28;4(11):14390-14397. doi: 10.1021/acsomega.9b01104. eCollection 2019 Sep 10.

28.

Subgroup Analysis of Japanese Patients in a Phase III Study of Atezolizumab in Extensive-stage Small-cell Lung Cancer (IMpower133).

Nishio M, Sugawara S, Atagi S, Akamatsu H, Sakai H, Okamoto I, Takayama K, Hayashi H, Nakagawa Y, Kawakami T.

Clin Lung Cancer. 2019 Nov;20(6):469-476.e1. doi: 10.1016/j.cllc.2019.07.005. Epub 2019 Jul 31.

PMID:
31466854
29.

Identification of new octamer transcription factor 1-target genes upregulated in castration-resistant prostate cancer.

Yamamoto S, Takayama KI, Obinata D, Fujiwara K, Ashikari D, Takahashi S, Inoue S.

Cancer Sci. 2019 Nov;110(11):3476-3485. doi: 10.1111/cas.14183. Epub 2019 Sep 16.

30.

Improved implant alignment accuracy with an accelerometer-based portable navigation system in medial unicompartmental knee arthroplasty.

Suda Y, Takayama K, Ishida K, Hayashi S, Hashimoto S, Niikura T, Matsushita T, Kuroda R, Matsumoto T.

Knee Surg Sports Traumatol Arthrosc. 2019 Aug 26. doi: 10.1007/s00167-019-05669-y. [Epub ahead of print]

PMID:
31451844
31.

Clinical features of immune-related thyroid dysfunction and its association with outcomes in patients with advanced malignancies treated by PD-1 blockade.

Sakakida T, Ishikawa T, Uchino J, Chihara Y, Komori S, Asai J, Narukawa T, Arai A, Kobayashi T, Tsunezuka H, Kosuga T, Konishi H, Hongo F, Inoue M, Hirano S, Ukimura O, Itoh Y, Taguchi T, Takayama K.

Oncol Lett. 2019 Aug;18(2):2140-2147. doi: 10.3892/ol.2019.10466. Epub 2019 Jun 12.

32.

A multicenter, open-label, single-arm study of anamorelin (ONO-7643) in advanced gastrointestinal cancer patients with cancer cachexia.

Hamauchi S, Furuse J, Takano T, Munemoto Y, Furuya K, Baba H, Takeuchi M, Choda Y, Higashiguchi T, Naito T, Muro K, Takayama K, Oyama S, Takiguchi T, Komura N, Tamura K.

Cancer. 2019 Dec 1;125(23):4294-4302. doi: 10.1002/cncr.32406. Epub 2019 Aug 15.

PMID:
31415709
33.

Development of Acute Retinal Necrosis in a Patient with Ocular Sarcoidosis: A Case Report.

Takayama K, Kaburaki T, Takeuchi M.

Ocul Immunol Inflamm. 2019;27(7):1067-1070. doi: 10.1080/09273948.2019.1635168. Epub 2019 Aug 15.

PMID:
31414927
34.

The presence of a cryptic barrier in the West Pacific Ocean suggests the effect of glacial climate changes on a widespread sea-dispersed plant, Vigna marina (Fabaceae).

Yamamoto T, Tsuda Y, Takayama K, Nagashima R, Tateishi Y, Kajita T.

Ecol Evol. 2019 Jul 4;9(15):8429-8440. doi: 10.1002/ece3.5099. eCollection 2019 Aug.

35.

Recurrent Hematomas following a Revision Total Hip Arthroplasty in Acquired Coagulation Factor XIII Deficiency.

Takashima Y, Hashimoto S, Kamenaga T, Tsubosaka M, Kuroda Y, Takeuchi K, Takayama K, Hayashi S, Kuroda R, Matsumoto T.

Case Rep Orthop. 2019 Jul 18;2019:4038963. doi: 10.1155/2019/4038963. eCollection 2019.

36.

Valgus Subsidence of the Tibial Component Caused by Tibial Component Malpositioning in Cementless Oxford Mobile-Bearing Unicompartmental Knee Arthroplasty.

Kamenaga T, Hiranaka T, Nakanishi Y, Takayama K, Kuroda R, Matsumoto T.

J Arthroplasty. 2019 Dec;34(12):3054-3060. doi: 10.1016/j.arth.2019.07.006. Epub 2019 Jul 16.

PMID:
31378509
37.

Denosumab Treatment Improved Health-Related Quality of Life in Osteoporosis: A Prospective Cohort Study.

Hayashi S, Fukuda K, Maeda T, Chinzei N, Kihara S, Miura Y, Sakai Y, Hashimoto S, Matsumoto T, Takayama K, Niikura T, Kuroda R.

JBMR Plus. 2019 May 7;3(7):e10191. doi: 10.1002/jbm4.10191. eCollection 2019 Jul.

38.

Carcinoembryonic antigen and CYFRA 21-1 responses as prognostic factors in advanced non-small cell lung cancer.

Yoshimura A, Uchino J, Hasegawa K, Tsuji T, Shiotsu S, Yuba T, Takumi C, Yamada T, Takayama K, Hiraoka N.

Transl Lung Cancer Res. 2019 Jun;8(3):227-234. doi: 10.21037/tlcr.2019.06.08.

39.

Randomized Phase II Study of Weekly Paclitaxel plus Carboplatin Versus Biweekly Paclitaxel plus Carboplatin for Patients with Previously Untreated Advanced Non-Small Cell Lung Cancer.

Takayama K, Ichiki M, Tokunaga S, Inoue K, Kawasaki M, Uchino J, Nakanishi Y.

Oncologist. 2019 Nov;24(11):1420-e1010. doi: 10.1634/theoncologist.2019-0513. Epub 2019 Jul 22.

40.

Intraoperative posterior movement of the tibia at 90° of flexion predicts worse postoperative flexion angles in cruciate-substituting total knee arthroplasty.

Inokuchi T, Ishida K, Takayama K, Shibanuma N, Hayashi S, Kurosaka M, Kuroda R, Matsumoto T.

Knee Surg Sports Traumatol Arthrosc. 2019 Jul 19. doi: 10.1007/s00167-019-05624-x. [Epub ahead of print]

PMID:
31324963
41.

Ginsenoside Rb1 inhibits vascular calcification as a selective androgen receptor modulator.

Nanao-Hamai M, Son BK, Komuro A, Asari Y, Hashizume T, Takayama KI, Ogawa S, Akishita M.

Eur J Pharmacol. 2019 Sep 15;859:172546. doi: 10.1016/j.ejphar.2019.172546. Epub 2019 Jul 15.

PMID:
31319068
42.

Rapamycin Rescues Age-Related Changes in Muscle-Derived Stem/Progenitor Cells from Progeroid Mice.

Kawakami Y, Hambright WS, Takayama K, Mu X, Lu A, Cummins JH, Matsumoto T, Yurube T, Kuroda R, Kurosaka M, Fu FH, Robbins PD, Niedernhofer LJ, Huard J.

Mol Ther Methods Clin Dev. 2019 May 30;14:64-76. doi: 10.1016/j.omtm.2019.05.011. eCollection 2019 Sep 13.

43.

Inactivation of myostatin by photo-oxygenation using catalyst-functionalized peptides.

Okamoto H, Taniguchi A, Usami S, Taguchi A, Takayama K, Hayashi Y.

Chem Commun (Camb). 2019 Aug 11;55(62):9108-9111. doi: 10.1039/c9cc04368c. Epub 2019 Jul 12.

PMID:
31298230
44.

In Vitro Epiretinal Membrane Model and Antibody Permeability: Relationship With Anti-VEGF Resistance in Diabetic Macular Edema.

Namba R, Kaneko H, Suzumura A, Shimizu H, Kataoka K, Takayama K, Yamada K, Funahashi Y, Ito S, Nonobe N, Terasaki H.

Invest Ophthalmol Vis Sci. 2019 Jul 1;60(8):2942-2949. doi: 10.1167/iovs.19-26788.

PMID:
31284311
45.

Prevalence and characteristics of occult hepatitis B virus infection in Japanese human immunodeficiency virus-infected patients.

Mitsumoto-Kaseida F, Murata M, Takayama K, Toyoda K, Ogawa E, Furusyo N, Hayashi J.

J Infect Chemother. 2020 Jan;26(1):28-32. doi: 10.1016/j.jiac.2019.06.003. Epub 2019 Jul 3.

PMID:
31279522
46.

Efficacy of Adalimumab for Chronic Vogt-Koyanagi-Harada Disease Refractory to Conventional Corticosteroids and Immunosuppressive Therapy and Complicated by Central Serous Chorioretinopathy.

Takayama K, Obata H, Takeuchi M.

Ocul Immunol Inflamm. 2019 Jul 3:1-4. doi: 10.1080/09273948.2019.1603312. [Epub ahead of print]

PMID:
31268769
47.

Adequate Positioning of the Tibial Component Is Key to Avoiding Bearing Impingement in Oxford Unicompartmental Knee Arthroplasty.

Kamenaga T, Hiranaka T, Takayama K, Tsubosaka M, Kuroda R, Matsumoto T.

J Arthroplasty. 2019 Nov;34(11):2606-2613. doi: 10.1016/j.arth.2019.05.054. Epub 2019 Jun 6.

PMID:
31235342
48.

Generation of Human iPSC-Derived Intestinal Epithelial Cell Monolayers by CDX2 Transduction.

Takayama K, Negoro R, Yamashita T, Kawai K, Ichikawa M, Mori T, Nakatsu N, Harada K, Ito S, Yamada H, Yamaura Y, Hirata K, Ishida S, Mizuguchi H.

Cell Mol Gastroenterol Hepatol. 2019;8(3):513-526. doi: 10.1016/j.jcmgh.2019.06.004. Epub 2019 Jun 19.

49.

Chain-Shortened Myostatin Inhibitory Peptides Improve Grip Strength in Mice.

Takayama K, Asari T, Saitoh M, Nirasawa K, Sasaki E, Roppongi Y, Nakamura A, Saga Y, Shimada T, Ikeyama H, Taguchi A, Taniguchi A, Negishi Y, Hayashi Y.

ACS Med Chem Lett. 2019 May 28;10(6):985-990. doi: 10.1021/acsmedchemlett.9b00174. eCollection 2019 Jun 13.

PMID:
31223459
50.

Synthesis of a one-handed helical polythiophene: a new approach using an axially chiral bithiophene with a fixed syn-conformation.

Ikai T, Takayama K, Wada Y, Minami S, Apiboon C, Shinohara KI.

Chem Sci. 2019 Apr 3;10(18):4890-4895. doi: 10.1039/c9sc00342h. eCollection 2019 May 14.

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