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Induction of bone repair in rat calvarial defects using a combination of hydroxyapatite with phosphatidylserine liposomes.

Hatakeyama J, Anan H, Hatakeyama Y, Matsumoto N, Takayama F, Wu Z, Matsuzaki E, Minakami M, Izumi T, Nakanishi H.

J Oral Sci. 2019;61(1):111-118. doi: 10.2334/josnusd.17-0488.


Relationship between oxygen cost and C-reactive protein response to marathon running in college recreational runners.

Takayama F, Aoyagi A, Takahashi K, Nabekura Y.

Open Access J Sports Med. 2018 Nov 27;9:261-268. doi: 10.2147/OAJSM.S183274. eCollection 2018.


Impaired neurite development associated with mitochondrial dysfunction in dopaminergic neurons differentiated from exfoliated deciduous tooth-derived pulp stem cells of children with autism spectrum disorder.

Nguyen HTN, Kato H, Masuda K, Yamaza H, Hirofuji Y, Sato H, Pham TTM, Takayama F, Sakai Y, Ohga S, Taguchi T, Nonaka K.

Biochem Biophys Rep. 2018 Sep 21;16:24-31. doi: 10.1016/j.bbrep.2018.09.004. eCollection 2018 Dec.


Author Correction: Infection of microglia with Porphyromonas gingivalis promotes cell migration and an inflammatory response through the gingipain-mediated activation of protease-activated receptor-2 in mice.

Liu Y, Wu Z, Nakanishi Y, Ni J, Hayashi Y, Takayama F, Zhou Y, Kadowaki T, Nakanishi H.

Sci Rep. 2018 Jul 4;8(1):10304. doi: 10.1038/s41598-018-27508-9.


Mitochondrial dysfunction in dopaminergic neurons differentiated from exfoliated deciduous tooth-derived pulp stem cells of a child with Rett syndrome.

Hirofuji S, Hirofuji Y, Kato H, Masuda K, Yamaza H, Sato H, Takayama F, Torio M, Sakai Y, Ohga S, Taguchi T, Nonaka K.

Biochem Biophys Res Commun. 2018 Apr 15;498(4):898-904. doi: 10.1016/j.bbrc.2018.03.077. Epub 2018 Mar 17.


Effects of Marathon Running on Aerobic Fitness and Performance in Recreational Runners One Week after a Race.

Takayama F, Aoyagi A, Shimazu W, Nabekura Y.

J Sports Med (Hindawi Publ Corp). 2017;2017:9402386. doi: 10.1155/2017/9402386. Epub 2017 Aug 24.


Infection of microglia with Porphyromonas gingivalis promotes cell migration and an inflammatory response through the gingipain-mediated activation of protease-activated receptor-2 in mice.

Liu Y, Wu Z, Nakanishi Y, Ni J, Hayashi Y, Takayama F, Zhou Y, Kadowaki T, Nakanishi H.

Sci Rep. 2017 Sep 18;7(1):11759. doi: 10.1038/s41598-017-12173-1. Erratum in: Sci Rep. 2018 Jul 4;8(1):10304.


Dysfunction in diurnal synaptic responses and social behavior abnormalities in cathepsin S-deficient mice.

Takayama F, Zhang X, Hayashi Y, Wu Z, Nakanishi H.

Biochem Biophys Res Commun. 2017 Aug 19;490(2):447-452. doi: 10.1016/j.bbrc.2017.06.061. Epub 2017 Jun 13.


Cathepsin B plays a critical role in inducing Alzheimer's disease-like phenotypes following chronic systemic exposure to lipopolysaccharide from Porphyromonas gingivalis in mice.

Wu Z, Ni J, Liu Y, Teeling JL, Takayama F, Collcutt A, Ibbett P, Nakanishi H.

Brain Behav Immun. 2017 Oct;65:350-361. doi: 10.1016/j.bbi.2017.06.002. Epub 2017 Jun 10.


A Case of Adenomyoepithelioma of the Breast Showing Strong Uptake of 18 F-Fluorodeoxyglucose on a Positron Emission Tomography.

Oba T, Maeno K, Ono M, Iesato A, Ito T, Kanai T, Mochizuki Y, Ito KI, Yoshizawa A, Takayama F.

Breast J. 2017 Mar;23(2):220-224. doi: 10.1111/tbj.12715. Epub 2016 Nov 7.


How does Eucommia leaf extract prevent smooth muscle cell proliferation induced by high-fat diets at the aortic tunica media?

Takayama F, Fujihara Y.

Hypertens Res. 2017 Jun;40(6):541-543. doi: 10.1038/hr.2017.22. Epub 2017 Feb 23. No abstract available.


Diurnal dynamic behavior of microglia in response to infected bacteria through the UDP-P2Y6 receptor system.

Takayama F, Hayashi Y, Wu Z, Liu Y, Nakanishi H.

Sci Rep. 2016 Jul 21;6:30006. doi: 10.1038/srep30006.


Overexpression of Cathepsin E Interferes with Neuronal Differentiation of P19 Embryonal Teratocarcinoma Cells by Degradation of N-cadherin.

Harada Y, Takayama F, Tanabe K, Ni J, Hayashi Y, Yamamoto K, Wu Z, Nakanishi H.

Cell Mol Neurobiol. 2017 Apr;37(3):437-443. doi: 10.1007/s10571-016-0376-x. Epub 2016 Apr 26.


Lipid-rich carcinoma of the breast that is strongly positive for estrogen receptor: a case report and literature review.

Oba T, Ono M, Iesato A, Hanamura T, Watanabe T, Ito T, Kanai T, Maeno K, Ito K, Tateishi A, Yoshizawa A, Takayama F.

Onco Targets Ther. 2016 Mar 18;9:1641-6. doi: 10.2147/OTT.S88726. eCollection 2016.


Muscarinic acetylcholine receptor M1 and M3 subtypes mediate acetylcholine-induced endothelium-independent vasodilatation in rat mesenteric arteries.

Tangsucharit P, Takatori S, Zamami Y, Goda M, Pakdeechote P, Kawasaki H, Takayama F.

J Pharmacol Sci. 2016 Jan;130(1):24-32. doi: 10.1016/j.jphs.2015.12.005. Epub 2016 Jan 8.


Nicotine facilitates reinnervation of phenol-injured perivascular adrenergic nerves in the rat mesenteric resistance artery.

Takatori S, Fujiwara H, Hagimori K, Hashikawa-Hobara N, Yokomizo A, Takayama F, Tangsucharit P, Ono N, Kawasaki H.

Eur J Pharmacol. 2015 Feb 5;748:1-9. doi: 10.1016/j.ejphar.2014.12.005. Epub 2014 Dec 13.


Oral administration of eicosapentaenoic acid or docosahexaenoic acid modifies cardiac function and ameliorates congestive heart failure in male rats.

Yamanushi TT, Kabuto H, Hirakawa E, Janjua N, Takayama F, Mankura M.

J Nutr. 2014 Apr;144(4):467-74. doi: 10.3945/jn.113.175125. Epub 2014 Feb 12.


Brazilian green propolis suppresses the hypoxia-induced neuroinflammatory responses by inhibiting NF-κB activation in microglia.

Wu Z, Zhu A, Takayama F, Okada R, Liu Y, Harada Y, Wu S, Nakanishi H.

Oxid Med Cell Longev. 2013;2013:906726. doi: 10.1155/2013/906726. Epub 2013 Aug 1.


Possible involvement of aiPLA2 in the phosphatidylserine-containing liposomes induced production of PGE2 and PGD2 in microglia.

Takayama F, Wu Z, Ma HM, Okada R, Hayashi Y, Nakanishi H.

J Neuroimmunol. 2013 Sep 15;262(1-2):121-4. doi: 10.1016/j.jneuroim.2013.06.011. Epub 2013 Jul 11.


Anti-oxidative and anti-inflammatory effects of spirulina on rat model of non-alcoholic steatohepatitis.

Pak W, Takayama F, Mine M, Nakamoto K, Kodo Y, Mankura M, Egashira T, Kawasaki H, Mori A.

J Clin Biochem Nutr. 2012 Nov;51(3):227-34. doi: 10.3164/jcbn.12-18. Epub 2012 Oct 12.


Do cholinergic nerves innervating rat mesenteric arteries regulate vascular tone?

Tangsucharit P, Takatori S, Sun P, Zamami Y, Goda M, Pakdeechote P, Takayama F, Kawasaki H.

Am J Physiol Regul Integr Comp Physiol. 2012 Dec;303(11):R1147-56. doi: 10.1152/ajpregu.00317.2012. Epub 2012 Oct 10.


Water extract of Vitis coignetiae Pulliat leaves attenuates oxidative stress and inflammation in progressive NASH rats.

Pak W, Takayama F, Hasegawa A, Mankura M, Egashira T, Ueki K, Nakamoto K, Kawasaki H, Mori A.

Acta Med Okayama. 2012;66(4):317-27.


Small peripheral lung carcinomas with five-year post-surgical follow-up: assessment by semi-automated volumetric measurement of tumour size, CT value and growth rate on TSCT.

Sone S, Hanaoka T, Ogata H, Takayama F, Watanabe T, Haniuda M, Kaneko K, Kondo R, Yoshida K, Honda T.

Eur Radiol. 2012 Jan;22(1):104-19. doi: 10.1007/s00330-011-2241-0. Epub 2011 Aug 17.


Structure-based design, synthesis, and nonalcoholic steatohepatitis (NASH)-preventive effect of phenylpropanoic acid peroxisome proliferator-activated receptor (PPAR) α-selective agonists.

Ban S, Kasuga J, Nakagome I, Nobusada H, Takayama F, Hirono S, Kawasaki H, Hashimoto Y, Miyachi H.

Bioorg Med Chem. 2011 May 15;19(10):3183-91. doi: 10.1016/j.bmc.2011.03.064. Epub 2011 Apr 8.


Effects of docosahexaenoic acid in an experimental rat model of nonalcoholic steatohepatitis.

Takayama F, Nakamoto K, Totani N, Yamanushi T, Kabuto H, Kaneyuki T, Mankura M.

J Oleo Sci. 2010;59(8):407-14.


A Novel Animal Model of Nonalcoholic Steatohepatitis (NASH): Hypoxemia Enhances the Development of NASH.

Takayama F, Egashira T, Kawasaki H, Mankura M, Nakamoto K, Okada S, Mori A.

J Clin Biochem Nutr. 2009 Nov;45(3):335-40. doi: 10.3164/jcbn.09-29. Epub 2009 Oct 28.


HRCT features of small peripheral lung carcinomas detected in a low-dose CT screening program.

Sone S, Matsumoto T, Honda T, Tsushima K, Takayama F, Hanaoka T, Kondo R, Haniuda M.

Acad Radiol. 2010 Jan;17(1):75-83. doi: 10.1016/j.acra.2009.08.003. Epub 2009 Oct 30.


Beneficial Effects of Fermented Green Tea Extract in a Rat Model of Non-alcoholic Steatohepatitis.

Nakamoto K, Takayama F, Mankura M, Hidaka Y, Egashira T, Ogino T, Kawasaki H, Mori A.

J Clin Biochem Nutr. 2009 May;44(3):239-46. doi: 10.3164/jcbn.08-256. Epub 2009 Apr 25.


Beneficial effects of Vitis coignetiae Pulliat leaves on nonalcoholic steatohepatitis in a rat model.

Takayama F, Nakamoto K, Kawasaki H, Mankura M, Egashira T, Ueki K, Hasegawa A, Okada S, Mori A.

Acta Med Okayama. 2009 Apr;63(2):105-11.


[Effect of postprandial hyperglycemia and hyperinsulinemia on vascular responsiveness].

Zamami Y, Takatori S, Iwatani Y, Yamawaki K, Miyashita S, Yabumae N, Takayama F, Mio M, Kawasaki H.

Yakugaku Zasshi. 2008 Mar;128(3):419-24. Review. Japanese.


Simultaneous solution to dark matter and flavor problems of supersymmetry.

Feng JL, Smith BT, Takayama F.

Phys Rev Lett. 2008 Jan 18;100(2):021302. Epub 2008 Jan 15.


Presence of local pleural adhesion in CT screening-detected small nodule in the lung periphery suggests noncancerous, inflammatory nature of the lesion.

Hanaoka T, Sone S, Takayama F, Hayano T, Yamaguchi S, Okada M.

Clin Imaging. 2007 Nov-Dec;31(6):385-9.


Long-term follow-up study of a population-based 1996-1998 mass screening programme for lung cancer using mobile low-dose spiral computed tomography.

Sone S, Nakayama T, Honda T, Tsushima K, Li F, Haniuda M, Takahashi Y, Suzuki T, Yamanda T, Kondo R, Hanaoka T, Takayama F, Kubo K, Fushimi H.

Lung Cancer. 2007 Dec;58(3):329-41. Epub 2007 Aug 6.


[Mechanisms underlying enhanced vasodilator responses to various vasodilator agents following endothelium removal in rat mesenteric resistance arteries].

Iwatani Y, Numa H, Atagi S, Takayama F, Mio M, Kawasaki H.

Yakugaku Zasshi. 2007 Apr;127(4):729-33. Review. Japanese.


CT findings of early-stage small cell lung cancer in a low-dose CT screening programme.

Sone S, Nakayama T, Honda T, Tsushima K, Li F, Haniuda M, Takahashi Y, Hanaoka T, Takayama F, Koizumi T, Kubo K, Yamanda T, Kondo R, Fushimi H, Suzuki T.

Lung Cancer. 2007 May;56(2):207-15. Epub 2007 Jan 25.


Oxidative stress, advanced glycation end product, and coronary artery calcification in hemodialysis patients.

Taki K, Takayama F, Tsuruta Y, Niwa T.

Kidney Int. 2006 Jul;70(1):218-24. Epub 2006 May 24.


Innervation and functional changes in mesenteric perivascular calcitonin gene-related peptide- and neuropeptide Y-containing nerves following topical phenol treatment.

Hobara N, Goda M, Kitamura Y, Takayama F, Kawasaki H.

Neuroscience. 2006 Aug 25;141(2):1087-99. Epub 2006 May 18.


Lower limit on dark matter production at the CERN Large Hadron Collider.

Feng JL, Su S, Takayama F.

Phys Rev Lett. 2006 Apr 21;96(15):151802. Epub 2006 Apr 19.


Superweakly interacting massive particle solutions to small scale structure problems.

Cembranos JA, Feng JL, Rajaraman A, Takayama F.

Phys Rev Lett. 2005 Oct 28;95(18):181301. Epub 2005 Oct 27.


MRI of the breast: comparison of MRI signals and histological characteristics of the same slices.

Kusama R, Takayama F, Tsuchiya S.

Med Mol Morphol. 2005 Dec;38(4):204-15. Review.


Histamine-induced vasodilation and vasoconstriction in the mesenteric resistance artery of the rat.

Jin H, Koyama T, Hatanaka Y, Akiyama S, Takayama F, Kawasaki H.

Eur J Pharmacol. 2006 Jan 4;529(1-3):136-44. Epub 2005 Dec 9.


Subcentimeter large cell neuroendocrine carcinoma of the lung.

Hanaoka T, Sone S, Ino H, Takayama F, Sato T, Kanaya H, Ogata H.

J Thorac Imaging. 2005 Nov;20(4):288-90.


Effect of adrenomedullin on adrenergic vasoconstriction in mesenteric resistance arteries of the rat.

Akiyama S, Hatanaka Y, Hobara N, Honghua J, Kosugi K, Takayama F, Kawasaki H.

J Pharmacol Sci. 2005 Nov;99(3):264-71. Epub 2005 Nov 1.


Neuronal nitric-oxide synthase inhibition facilitates adrenergic neurotransmission in rat mesenteric resistance arteries.

Hatanaka Y, Hobara N, Honghua J, Akiyama S, Nawa H, Kobayashi Y, Takayama F, Gomita Y, Kawasaki H.

J Pharmacol Exp Ther. 2006 Feb;316(2):490-7. Epub 2005 Oct 19.


Possible link between glycolysis and apoptosis induced by sodium fluoride.

Otsuki S, Morshed SR, Chowdhury SA, Takayama F, Satoh T, Hashimoto K, Sugiyama K, Amano O, Yasui T, Yokote Y, Akahane K, Sakagami H.

J Dent Res. 2005 Oct;84(10):919-23.


Changes in fluoride sensitivity during in vitro senescence of normal human oral cells.

Satoh R, Kishino K, Morshed SR, Takayama F, Otsuki S, Suzuki F, Hashimoto K, Kikuchi H, Nishikawa H, Yasui T, Sakagami H.

Anticancer Res. 2005 May-Jun;25(3B):2085-90.


Long-term inhibition of angiotensin prevents reduction of periarterial innervation of calcitonin gene-related peptide (CGRP)-containing nerves in spontaneously hypertensive rats.

Hobara N, Gessei-Tsutsumi N, Goda M, Takayama F, Akiyama S, Kurosaki Y, Kawasaki H.

Hypertens Res. 2005 May;28(5):465-74.


Comparison of bronchoscopic diagnosis for peripheral pulmonary nodule under fluoroscopic guidance with CT guidance.

Tsushima K, Sone S, Hanaoka T, Takayama F, Honda T, Kubo K.

Respir Med. 2006 Apr;100(4):737-45. Epub 2005 Aug 26.

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