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Items: 1 to 50 of 126

1.

Muraminomicins, new lipo-nucleoside antibiotics from Streptosporangium sp. SANK 60501-structure elucidations of muraminomicins and supply of the core component for derivatization.

Fujita Y, Kagoshima Y, Masuda T, Kizuka M, Ogawa Y, Endo S, Nishigoori H, Saito K, Takasugi K, Miura M, Murakami R, Muramatsu Y, Tokumitsu A, Koga T, Iizuka M, Aoyagi A, Suzuki T, Suzuki T, Suzuki Y, Ishida O, Nakahira T, Miyakoshi S, Konosu T, Takatsu T.

J Antibiot (Tokyo). 2019 Dec;72(12):943-955. doi: 10.1038/s41429-019-0215-7. Epub 2019 Aug 14.

PMID:
31413314
2.

IL-6 is an independent predictive factor of drug survival after dose escalation of infliximab in patients with rheumatoid arthritis.

Takasugi K, Nishida K, Natsumeda M, Yamashita M, Yamamoto W, Ezawa K.

Mod Rheumatol. 2018 May;28(3):452-460. doi: 10.1080/14397595.2017.1361802. Epub 2017 Aug 22.

PMID:
28828944
3.

Novel autoantibody against the β2-glycoprotein I/human leucocyte antigen-DR complex in patients with refractory cutaneous ulcers.

Arase N, Tanimura K, Jin H, Yamaoka T, Kishibe M, Nishioka M, Kiyohara E, Tani M, Matsuoka S, Ohmura K, Takasugi K, Yamamoto T, Murota H, Arase H, Katayama I.

Br J Dermatol. 2018 Jan;178(1):272-275. doi: 10.1111/bjd.15571. Epub 2017 Oct 6. No abstract available.

PMID:
28403571
4.

A Fatal Case of Metformin-associated Lactic Acidosis.

Ozeki T, Kawato R, Watanabe M, Minatoguchi S, Murai Y, Ryuge A, Takasugi K, Hamada T, Oyama Y, Nomura A, Tomino T, Shimizu H, Fujita Y.

Intern Med. 2016;55(7):775-8. doi: 10.2169/internalmedicine.55.5415. Epub 2016 Apr 1.

5.

Coverage induced structural transformations of tetracene on Ag(110).

Takasugi K, Yokoyama T.

J Chem Phys. 2016 Mar 14;144(10):104702. doi: 10.1063/1.4943576.

PMID:
26979699
6.

Non-autoimmune combined factor XIII A and B subunit deficiencies in rheumatoid arthritis patients treated with anti-interleukin-6 receptor monoclonal antibody (tocilizumab).

Souri M, Mokuda S, Inanami H, Osaki T, Takasugi K, Ichinose A.

Thromb Res. 2016 Apr;140:100-105. doi: 10.1016/j.thromres.2016.02.026. Epub 2016 Feb 26.

PMID:
26938156
7.

Study on the frequency and risk factors of moderate-to-severe sleep apnea syndrome in rheumatoid arthritis.

Mutoh T, Okuda Y, Mokuda S, Sawada N, Matoba K, Yamada A, Jouyama K, Onishi M, Takasugi K.

Mod Rheumatol. 2016 Sep;26(5):681-4. doi: 10.3109/14397595.2015.1131352. Epub 2016 Feb 16.

PMID:
26709121
8.

Machine-Learning-Based Prediction of a Missed Scheduled Clinical Appointment by Patients With Diabetes.

Kurasawa H, Hayashi K, Fujino A, Takasugi K, Haga T, Waki K, Noguchi T, Ohe K.

J Diabetes Sci Technol. 2016 May 3;10(3):730-6. doi: 10.1177/1932296815614866. Print 2016 May.

9.

CD1a+ survivin+ dendritic cell infiltration in dermal lesions of systemic sclerosis.

Mokuda S, Miyazaki T, Ubara Y, Kanno M, Sugiyama E, Takasugi K, Masumoto J.

Arthritis Res Ther. 2015 Sep 30;17:275. doi: 10.1186/s13075-015-0785-0.

10.

The proto-oncogene survivin splice variant 2B is induced by PDGF and leads to cell proliferation in rheumatoid arthritis fibroblast-like synoviocytes.

Mokuda S, Miyazaki T, Ito Y, Yamasaki S, Inoue H, Guo Y, Kong WS, Kanno M, Takasugi K, Sugiyama E, Masumoto J.

Sci Rep. 2015 May 22;5:9795. doi: 10.1038/srep09795.

11.

Anti-citrullinated peptide/protein antibody (ACPA)-negative RA shares a large proportion of susceptibility loci with ACPA-positive RA: a meta-analysis of genome-wide association study in a Japanese population.

Terao C, Ohmura K, Kochi Y, Ikari K, Okada Y, Shimizu M, Nishina N, Suzuki A, Myouzen K, Kawaguchi T, Takahashi M, Takasugi K, Murasawa A, Mizuki S, Iwahashi M, Funahashi K, Natsumeda M, Furu M, Hashimoto M, Ito H, Fujii T, Ezawa K, Matsubara T, Takeuchi T, Kubo M, Yamada R, Taniguchi A, Yamanaka H, Momohara S, Yamamoto K, Mimori T, Matsuda F.

Arthritis Res Ther. 2015 Apr 18;17:104. doi: 10.1186/s13075-015-0623-4. Review.

12.

An association between amino acid position 74 of HLA-DRB1 and anti-citrullinated protein antibody levels in Japanese patients with anti-citrullinated protein antibody-positive rheumatoid arthritis.

Terao C, Suzuki A, Ikari K, Kochi Y, Ohmura K, Katayama M, Nakabo S, Yamamoto N, Suzuki T, Iwamoto T, Yurugi K, Miura Y, Maekawa T, Takasugi K, Kubo M, Saji H, Taniguchi A, Momohara S, Yamamoto K, Yamanaka H, Mimori T, Matsuda F.

Arthritis Rheumatol. 2015 May;67(8):2038-45. doi: 10.1002/art.39133.

13.

Sustainable Efficacy of Switching From Intravenous to Subcutaneous Tocilizumab Monotherapy in Patients With Rheumatoid Arthritis.

Ogata A, Atsumi T, Fukuda T, Hirabayashi Y, Inaba M, Ishiguro N, Kai M, Kawabata D, Kida D, Kohsaka H, Matsumura R, Minota S, Mukai M, Sumida T, Takasugi K, Tamaki S, Takeuchi T, Ueda A, Yamamoto K, Yamanaka H, Yoshifuji H, Nomura A; Musashi Study Investigators.

Arthritis Care Res (Hoboken). 2015 Oct;67(10):1354-62. doi: 10.1002/acr.22598.

14.

β2-Glycoprotein I/HLA class II complexes are novel autoantigens in antiphospholipid syndrome.

Tanimura K, Jin H, Suenaga T, Morikami S, Arase N, Kishida K, Hirayasu K, Kohyama M, Ebina Y, Yasuda S, Horita T, Takasugi K, Ohmura K, Yamamoto K, Katayama I, Sasazuki T, Lanier LL, Atsumi T, Yamada H, Arase H.

Blood. 2015 Apr 30;125(18):2835-44. doi: 10.1182/blood-2014-08-593624. Epub 2015 Mar 2.

15.

Note: application of UF-4 emulsion films to detect low-energy ions from plasmas produced by laser ablation.

Nishio M, Shrestha I, Kantsyrev VL, Tooth M, Takasugi K.

Rev Sci Instrum. 2014 Apr;85(4):046106. doi: 10.1063/1.4870415.

PMID:
24784684
16.

Autoantibodies to IgG/HLA class II complexes are associated with rheumatoid arthritis susceptibility.

Jin H, Arase N, Hirayasu K, Kohyama M, Suenaga T, Saito F, Tanimura K, Matsuoka S, Ebina K, Shi K, Toyama-Sorimachi N, Yasuda S, Horita T, Hiwa R, Takasugi K, Ohmura K, Yoshikawa H, Saito T, Atsumi T, Sasazuki T, Katayama I, Lanier LL, Arase H.

Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):3787-92. doi: 10.1073/pnas.1401105111. Epub 2014 Feb 24.

17.

Rational/antiemotional behaviors in interpersonal relationships and the functional prognosis of patients with rheumatoid arthritis: a Japanese multicenter, longitudinal study.

Nagano J, Morita T, Taneichi K, Nagaoka S, Katsube S, Asai T, Yukioka M, Takasugi K, Kondo M, Nishibayashi Y.

Biopsychosoc Med. 2014 Feb 24;8(1):8. doi: 10.1186/1751-0759-8-8.

18.

Epstein-Barr virus-related MTX-LPD in rheumatoid arthritis patients exhibits a viral pattern of the CD64 and CD35 expression on neutrophils: three case reports.

Mokuda S, Miyazaki T, Saeki Y, Masumoto J, Kanno M, Takasugi K.

Mod Rheumatol. 2015 Jan;25(1):166-8. doi: 10.3109/14397595.2013.875641. Epub 2014 Feb 5. No abstract available.

PMID:
24499448
19.

Tocilizumab improved clinical symptoms of a patient with systemic tophaceous gout who had symmetric polyarthritis and fever: An alternative treatment by blockade of interleukin-6 signaling.

Mokuda S, Kanno M, Takasugi K, Okumura C, Ito Y, Masumoto J.

SAGE Open Med Case Rep. 2014 Jan 8;2:2050313X13519774. doi: 10.1177/2050313X13519774. eCollection 2014.

20.

Comparison of the clinical utility of tocilizumab and anti-TNF therapy in AA amyloidosis complicating rheumatic diseases.

Okuda Y, Ohnishi M, Matoba K, Jouyama K, Yamada A, Sawada N, Mokuda S, Murata Y, Takasugi K.

Mod Rheumatol. 2014 Jan;24(1):137-43. doi: 10.3109/14397595.2013.854048.

PMID:
24261770
21.

Retreatment efficacy and safety of tocilizumab in patients with rheumatoid arthritis in recurrence (RESTORE) study.

Nishimoto N, Amano K, Hirabayashi Y, Horiuchi T, Ishii T, Iwahashi M, Iwamoto M, Kohsaka H, Kondo M, Matsubara T, Mimura T, Miyahara H, Ohta S, Saeki Y, Saito K, Sano H, Takasugi K, Takeuchi T, Tohma S, Tsuru T, Ueki Y, Yamana J, Hashimoto J, Matsutani T, Murakami M, Takagi N.

Mod Rheumatol. 2014 Jan;24(1):26-32. doi: 10.3109/14397595.2013.854080.

PMID:
24261755
22.

Drug free REmission/low disease activity after cessation of tocilizumab (Actemra) Monotherapy (DREAM) study.

Nishimoto N, Amano K, Hirabayashi Y, Horiuchi T, Ishii T, Iwahashi M, Iwamoto M, Kohsaka H, Kondo M, Matsubara T, Mimura T, Miyahara H, Ohta S, Saeki Y, Saito K, Sano H, Takasugi K, Takeuchi T, Tohma S, Tsuru T, Ueki Y, Yamana J, Hashimoto J, Matsutani T, Murakami M, Takagi N.

Mod Rheumatol. 2014 Jan;24(1):17-25. doi: 10.3109/14397595.2013.854079.

PMID:
24261754
23.

Tocilizumab induced acquired factor XIII deficiency in patients with rheumatoid arthritis.

Mokuda S, Murata Y, Sawada N, Matoba K, Yamada A, Onishi M, Okuda Y, Jouyama K, Sugiyama E, Takasugi K.

PLoS One. 2013 Aug 1;8(8):e69944. doi: 10.1371/journal.pone.0069944. Print 2013.

24.

Multiple gastric G1 neuroendocrine tumors with venous and lymphatic invasion.

Tatsuta T, Yoshimura T, Hasui K, Takasugi K, Sawaya M, Hanabata N, Shimoyama T, Kijima H, Fukuda S.

Intern Med. 2013;52(15):1697-701. Epub 2012 Mar 1.

25.

D-penicillamine-induced glomerulonephritis with crescent formation: Remission following drug discontinuation.

Mokuda S, Onishi M, Takasugi K.

Indian J Nephrol. 2013 May;23(3):226-8. doi: 10.4103/0971-4065.111862.

26.

Rapidly progressive and fatal neurocutaneous melanosis presenting as recurrent headache.

Yamazaki Y, Matsuzawa T, Takasugi K, Suzuki N, Kanda M, Kobayashi I.

Pediatr Int. 2013 Apr;55(2):240-3. doi: 10.1111/j.1442-200X.2012.03653.x.

PMID:
23679165
27.

Serum undercarboxylated osteocalcin level increases with 48 weeks of teriparatide treatment in pre-treated elderly rheumatoid arthritis patients who use anti-resorptive drugs.

Mokuda S, Sawada N, Matoba K, Yamada A, Onishi M, Okuda Y, Jouyama K, Murata Y, Takasugi K.

J Endocrinol Invest. 2012 Oct;35(9):796-9.

PMID:
23135318
28.

Towards a beyond 1 GHz solid-state nuclear magnetic resonance: external lock operation in an external current mode for a 500 MHz nuclear magnetic resonance.

Takahashi M, Ebisawa Y, Tennmei K, Yanagisawa Y, Hosono M, Takasugi K, Hase T, Miyazaki T, Fujito T, Nakagome H, Kiyoshi T, Yamazaki T, Maeda H.

Rev Sci Instrum. 2012 Oct;83(10):105110. doi: 10.1063/1.4757576.

PMID:
23126807
29.

ACPA-negative RA consists of two genetically distinct subsets based on RF positivity in Japanese.

Terao C, Ohmura K, Ikari K, Kochi Y, Maruya E, Katayama M, Yurugi K, Shimada K, Murasawa A, Honjo S, Takasugi K, Matsuo K, Tajima K, Suzuki A, Yamamoto K, Momohara S, Yamanaka H, Yamada R, Saji H, Matsuda F, Mimori T.

PLoS One. 2012;7(7):e40067. doi: 10.1371/journal.pone.0040067. Epub 2012 Jul 6.

30.

Influence of low air humidity and low root temperature on water uptake, growth and aquaporin expression in rice plants.

Kuwagata T, Ishikawa-Sakurai J, Hayashi H, Nagasuga K, Fukushi K, Ahamed A, Takasugi K, Katsuhara M, Murai-Hatano M.

Plant Cell Physiol. 2012 Aug;53(8):1418-31. doi: 10.1093/pcp/pcs087. Epub 2012 Jun 8.

PMID:
22685088
31.

Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.

Okada Y, Terao C, Ikari K, Kochi Y, Ohmura K, Suzuki A, Kawaguchi T, Stahl EA, Kurreeman FA, Nishida N, Ohmiya H, Myouzen K, Takahashi M, Sawada T, Nishioka Y, Yukioka M, Matsubara T, Wakitani S, Teshima R, Tohma S, Takasugi K, Shimada K, Murasawa A, Honjo S, Matsuo K, Tanaka H, Tajima K, Suzuki T, Iwamoto T, Kawamura Y, Tanii H, Okazaki Y, Sasaki T, Gregersen PK, Padyukov L, Worthington J, Siminovitch KA, Lathrop M, Taniguchi A, Takahashi A, Tokunaga K, Kubo M, Nakamura Y, Kamatani N, Mimori T, Plenge RM, Yamanaka H, Momohara S, Yamada R, Matsuda F, Yamamoto K.

Nat Genet. 2012 Mar 25;44(5):511-6. doi: 10.1038/ng.2231.

PMID:
22446963
32.

Ageing: a risk factor for amyloid A amyloidosis in rheumatoid arthritis.

Okuda Y, Yamada T, Matsuura M, Takasugi K, Goto M.

Amyloid. 2012 Mar;19(1):58. doi: 10.3109/13506129.2011.650248. Epub 2012 Feb 1. No abstract available.

PMID:
22292892
33.

[A supratentorial primitive neuroectodermal tumor exhibiting pathological characteristics of medulloepithelioma: a case report].

Ishi Y, Suzuki N, Takasugi K, Tsuda H, Tateno M, Tanaka S.

No Shinkei Geka. 2012 Feb;40(2):159-65. Japanese.

PMID:
22281469
34.
35.

Quantitative effect of HLA-DRB1 alleles to ACPA levels in Japanese rheumatoid arthritis: no strong genetic impact of shared epitope to ACPA levels after stratification of HLA-DRB1*09:01.

Terao C, Ikari K, Ohmura K, Suzuki T, Iwamoto T, Takasugi K, Saji H, Taniguchi A, Momohara S, Yamanaka H, Matsuda F, Mimori T.

Ann Rheum Dis. 2012 Jun;71(6):1095-7. doi: 10.1136/annrheumdis-2011-200907. Epub 2012 Jan 10. No abstract available.

PMID:
22233603
36.

Inhibition of TNF-induced IL-6 by the TWEAK-Fn14 interaction in rheumatoid arthritis fibroblast like synoviocytes.

Yamana J, Morand EF, Manabu T, Sunahori K, Takasugi K, Makino H, Yamamura M.

Cell Immunol. 2012;272(2):293-8. doi: 10.1016/j.cellimm.2011.09.004. Epub 2011 Sep 22.

PMID:
22055894
37.

Post-menopausal women with rheumatoid arthritis who are treated with raloxifene or alendronate or glucocorticoids have lower serum undercarboxylated osteocalcin levels.

Mokuda S, Okuda Y, Onishi M, Sawada N, Matoba K, Yamada A, Jouyama K, Takasugi K.

J Endocrinol Invest. 2012 Jul;35(7):661-4. doi: 10.3275/7971. Epub 2011 Sep 30.

PMID:
21970822
38.

A large-scale association study identified multiple HLA-DRB1 alleles associated with ACPA-negative rheumatoid arthritis in Japanese subjects.

Terao C, Ohmura K, Kochi Y, Ikari K, Maruya E, Katayama M, Shimada K, Murasawa A, Honjo S, Takasugi K, Matsuo K, Tajima K, Suzuki A, Yamamoto K, Momohara S, Yamanaka H, Yamada R, Saji H, Matsuda F, Mimori T.

Ann Rheum Dis. 2011 Dec;70(12):2134-9. doi: 10.1136/annrheumdis-2011-200353. Epub 2011 Aug 27.

39.

Ageing: a risk factor for amyloid A amyloidosis in rheumatoid arthritis.

Okuda Y, Yamada T, Matsuura M, Takasugi K, Goto M.

Amyloid. 2011 Sep;18(3):108-11. doi: 10.3109/13506129.2011.582198. Epub 2011 Jun 1.

PMID:
21627560
40.

Histopathological phenotypes of early gastric cancer and its background mucosa.

Kudo Y, Morohashi S, Takasugi K, Tsutsumi S, Ogasawara H, Hanabata N, Yoshimura T, Sato F, Fukuda S, Kijima H.

Biomed Res. 2011 Apr;32(2):127-34.

41.

L1 Cell adhesion molecule (L1CAM) expression at the cancer invasive front is a novel prognostic marker of pancreatic ductal adenocarcinoma.

Tsutsumi S, Morohashi S, Kudo Y, Akasaka H, Ogasawara H, Ono M, Takasugi K, Ishido K, Hakamada K, Kijima H.

J Surg Oncol. 2011 Jun 1;103(7):669-73. doi: 10.1002/jso.21880. Epub 2011 Feb 28.

PMID:
21360711
42.

Eight case reports on sex-hormone profiles in sexually mature male Down syndrome.

Suzuki K, Nakajima K, Kamimura S, Takasugi K, Suzuki Y, Sekine H, Ishii N.

Int J Urol. 2010 Dec;17(12):1008-10. doi: 10.1111/j.1442-2042.2010.02621.x. Epub 2010 Oct 4.

43.

Successful tocilizumab treatment in a patient with adult-onset Still's disease complicated by chronic active hepatitis B and amyloid A amyloidosis.

Kishida D, Okuda Y, Onishi M, Takebayashi M, Matoba K, Jouyama K, Yamada A, Sawada N, Mokuda S, Takasugi K.

Mod Rheumatol. 2011 Apr;21(2):215-8. doi: 10.1007/s10165-010-0365-8. Epub 2010 Oct 8.

PMID:
20931272
44.

Anti-citrullinated peptide antibody-negative RA is a genetically distinct subset: a definitive study using only bone-erosive ACPA-negative rheumatoid arthritis.

Ohmura K, Terao C, Maruya E, Katayama M, Matoba K, Shimada K, Murasawa A, Honjo S, Takasugi K, Tohma S, Matsuo K, Tajima K, Yukawa N, Kawabata D, Nojima T, Fujii T, Yamada R, Saji H, Matsuda F, Mimori T.

Rheumatology (Oxford). 2010 Dec;49(12):2298-304. doi: 10.1093/rheumatology/keq273. Epub 2010 Sep 9.

45.

Increased activity and expression of histone deacetylase 1 in relation to tumor necrosis factor-alpha in synovial tissue of rheumatoid arthritis.

Kawabata T, Nishida K, Takasugi K, Ogawa H, Sada K, Kadota Y, Inagaki J, Hirohata S, Ninomiya Y, Makino H.

Arthritis Res Ther. 2010;12(4):R133. doi: 10.1186/ar3071. Epub 2010 Jul 7.

46.

Efficacy and safety of tacrolimus treatment for rheumatoid arthritis patients undergoing hemodialysis.

Yamashita M, Natsumeda M, Takasugi K, Ueno A, Ezawa K, Ezawa K.

Mod Rheumatol. 2008;18(3):296-300. doi: 10.1007/s10165-008-0044-1. Epub 2008 Mar 6.

PMID:
18322644
47.

Preemptive therapy with ganciclovir 5 mg/kg once daily for cytomegalovirus infection after unrelated cord blood transplantation.

Tomonari A, Takahashi S, Ooi J, Tsukada N, Konuma T, Kobayashi T, Takasugi K, Iseki T, Tojo A, Asano S.

Bone Marrow Transplant. 2008 Feb;41(4):371-6. Epub 2007 Nov 5.

PMID:
17982495
48.

Early-onset pulmonary complication showing organizing pneumonia pattern following cord blood transplantation in adults.

Tomonari A, Tsukada N, Takahashi S, Ooi J, Konuma T, Kobayashi T, Fukuno K, Takasugi K, Fujii T, Endo T, Iwamoto A, Oyaizu N, Tojo A, Asanoa S.

Int J Hematol. 2007 May;85(4):364-6. No abstract available.

PMID:
17483084
49.

Bacterial bloodstream infection in neutropenic adult patients after myeloablative cord blood transplantation: experience of a single institution in Japan.

Tomonari A, Takahashi S, Ooi J, Tsukada N, Konuma T, Kobayashi T, Sato A, Takasugi K, Iseki T, Tojo A, Asano S.

Int J Hematol. 2007 Apr;85(3):238-41.

PMID:
17483061
50.

Recruitment of CD16+ monocytes into synovial tissues is mediated by fractalkine and CX3CR1 in rheumatoid arthritis patients.

Yano R, Yamamura M, Sunahori K, Takasugi K, Yamana J, Kawashima M, Makino H.

Acta Med Okayama. 2007 Apr;61(2):89-98.

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