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Letter in reply to: 'therapeutic misconception and the role of the Research Ethics Committee'.

Takashima K, Inoue Y, Tashiro S, Muto K.

Regen Med. 2019 Aug 22. doi: 10.2217/rme-2019-0041. [Epub ahead of print] No abstract available.


Endoscopic sclerotherapy under balloon-assisted enteroscopy for hemorrhagic jejunal varices after choledocho-jejunostomy.

Takashima K, Matsui S, Komeda Y, Nagai T, Toshiharu S, Kashida H, Kudo M.

Endoscopy. 2019 Aug 21. doi: 10.1055/a-0987-9780. [Epub ahead of print] No abstract available.


Challenges in the use of zinc and its alloys as biodegradable metals: Perspective from biomechanical compatibility.

Li G, Yang H, Zheng Y, Chen XH, Yang JA, Zhu D, Ruan L, Takashima K.

Acta Biomater. 2019 Jul 23. pii: S1742-7061(19)30527-6. doi: 10.1016/j.actbio.2019.07.038. [Epub ahead of print] Review.


Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome.

Boulias K, Toczydłowska-Socha D, Hawley BR, Liberman N, Takashima K, Zaccara S, Guez T, Vasseur JJ, Debart F, Aravind L, Jaffrey SR, Greer EL.

Mol Cell. 2019 Aug 8;75(3):631-643.e8. doi: 10.1016/j.molcel.2019.06.006. Epub 2019 Jul 3.


Occurrence of neonicotinoids and fipronil in estuaries and their potential risks to aquatic invertebrates.

Hano T, Ito K, Ohkubo N, Sakaji H, Watanabe A, Takashima K, Sato T, Sugaya T, Matsuki K, Onduka T, Ito M, Somiya R, Mochida K.

Environ Pollut. 2019 Sep;252(Pt A):205-215. doi: 10.1016/j.envpol.2019.05.067. Epub 2019 May 14.


Formal Syntheses of (-)-Lepadiformines A, C, and (-)-Fasicularin.

Takashima K, Hayakawa D, Gouda H, Toyooka N.

J Org Chem. 2019 May 3;84(9):5222-5229. doi: 10.1021/acs.joc.9b00071. Epub 2019 Apr 15.


Second nationwide surveillance of bacterial pathogens in patients with acute uncomplicated cystitis conducted by Japanese Surveillance Committee from 2015 to 2016: antimicrobial susceptibility of Escherichia coli, Klebsiella pneumoniae, and Staphylococcus saprophyticus.

Hayami H, Takahashi S, Ishikawa K, Yasuda M, Yamamoto S, Wada K, Kobayashi K, Hamasuna R, Minamitani S, Matsumoto T, Kiyota H, Tateda K, Sato J, Hanaki H, Masumori N, Nishiyama H, Miyazaki J, Fujimoto K, Tanaka K, Uehara S, Matsubara A, Ito K, Hayashi K, Kurimura Y, Ito S, Takeuchi T, Narita H, Izumitani M, Nishimura H, Kawahara M, Hara M, Hosobe T, Takashima K, Chokyu H, Matsumura M, Ihara H, Uno S, Monden K, Sumii T, Kawai S, Kariya S, Sato T, Yoshioka M, Kadena H, Matsushita S, Nishi S, Hosokawa Y, Shirane T, Yoh M, Watanabe S, Makinose S, Uemura T, Goto H.

J Infect Chemother. 2019 Jun;25(6):413-422. doi: 10.1016/j.jiac.2019.02.021. Epub 2019 Mar 21.


Objective evaluation of the visibility of colorectal lesions using eye tracking.

Kumahara K, Ikematsu H, Shinmura K, Murano T, Inaba A, Okumura K, Nishihara K, Sunakawa H, Furue Y, Ito R, Sato D, Minamide T, Okamoto N, Yamamoto Y, Suyama M, Takashima K, Nakajo K, Yoda Y, Hori K, Oono Y, Yano T.

Dig Endosc. 2019 Sep;31(5):552-557. doi: 10.1111/den.13397. Epub 2019 Apr 8.


Clinicopathological features and endoscopic characteristics of inverted sessile serrated adenomas/polyps.

Takashima K, Oono Y, Kojima M, Ikematsu H, Akimoto T, Yano T.

Endosc Int Open. 2019 Mar;7(3):E330-E336. doi: 10.1055/a-0820-2179. Epub 2019 Feb 28.


Technical feasibility of endoscopic submucosal dissection for local failure after chemoradiotherapy or radiotherapy for esophageal squamous cell carcinoma.

Nakajo K, Yoda Y, Hori K, Takashima K, Sinmura K, Oono Y, Ikematsu H, Yano T.

Gastrointest Endosc. 2018 Oct;88(4):637-646. doi: 10.1016/j.gie.2018.06.033. Epub 2018 Jul 6.


Effectiveness of scheduled postoperative intravenous acetaminophen for colon cancer surgery pain.

Horita E, Takahashi Y, Takashima K, Saito K, Takashima Y, Munemoto Y.

J Pharm Health Care Sci. 2018 Jul 6;4:19. doi: 10.1186/s40780-018-0115-1. eCollection 2018.


Human epidermal growth factor receptor 2-, epidermal growth factor receptor-, and mesenchymal epithelial transition factor-positive sites of gastric cancer using surgical samples.

Oono Y, Kuwata T, Takashima K, Shinmura K, Hori K, Yoda Y, Ikematsu H, Shitara K, Kinoshita T, Yano T.

Gastric Cancer. 2019 Mar;22(2):335-343. doi: 10.1007/s10120-018-0853-7. Epub 2018 Jun 27.


Atmospheric-pressure plasma irradiation can disrupt tobacco mosaic virus particles and RNAs to inactivate their infectivity.

Hanbal SE, Takashima K, Miyashita S, Ando S, Ito K, Elsharkawy MM, Kaneko T, Takahashi H.

Arch Virol. 2018 Oct;163(10):2835-2840. doi: 10.1007/s00705-018-3909-4. Epub 2018 Jun 14.


Ethical concerns on sharing genomic data including patients' family members.

Takashima K, Maru Y, Mori S, Mano H, Noda T, Muto K.

BMC Med Ethics. 2018 Jun 18;19(1):61. doi: 10.1186/s12910-018-0310-5.


Vaccine immunotherapy with ARNAX induces tumor-specific memory T cells and durable anti-tumor immunity in mouse models.

Takeda Y, Yoshida S, Takashima K, Ishii-Mugikura N, Shime H, Seya T, Matsumoto M.

Cancer Sci. 2018 Jul;109(7):2119-2129. doi: 10.1111/cas.13649. Epub 2018 Jun 16.


TICAM-1 is dispensable in STING-mediated innate immune responses in myeloid immune cells.

Takashima K, Oshiumi H, Matsumoto M, Seya T.

Biochem Biophys Res Commun. 2018 May 23;499(4):985-991. doi: 10.1016/j.bbrc.2018.04.035. Epub 2018 Apr 9.


Which Classification System Is Most Useful for Classifying Osteonecrosis of the Femoral Head?

Takashima K, Sakai T, Hamada H, Takao M, Sugano N.

Clin Orthop Relat Res. 2018 Jun;476(6):1240-1249. doi: 10.1007/s11999.0000000000000245.


Adjuvant immunotherapy for cancer: both dendritic cell-priming and check-point inhibitor blockade are required for immunotherapy.

Seya T, Takeda Y, Takashima K, Yoshida S, Azuma M, Matsumoto M.

Proc Jpn Acad Ser B Phys Biol Sci. 2018;94(3):153-160. doi: 10.2183/pjab.94.011. Review.


Clinicopathological features and endoscopic findings of HER2-positive gastric cancer.

Oono Y, Kuwata T, Takashima K, Yoda Y, Ikematsu H, Shitara K, Kinoshita T, Yano T.

Surg Endosc. 2018 Sep;32(9):3964-3971. doi: 10.1007/s00464-018-6138-8. Epub 2018 Mar 2.


Toll-like receptor 3 signal augments radiation-induced tumor growth retardation in a murine model.

Yoshida S, Shime H, Takeda Y, Nam JM, Takashima K, Matsumoto M, Shirato H, Kasahara M, Seya T.

Cancer Sci. 2018 Apr;109(4):956-965. doi: 10.1111/cas.13543. Epub 2018 Mar 25.


cGAMP Promotes Germinal Center Formation and Production of IgA in Nasal-Associated Lymphoid Tissue.

Takaki H, Takashima K, Oshiumi H, Ainai A, Suzuki T, Hasegawa H, Matsumoto M, Seya T.

Med Sci (Basel). 2017 Dec 18;5(4). pii: E35. doi: 10.3390/medsci5040035.


Risk Factors for Postoperative Bleeding in Endoscopic Submucosal Dissection of Colorectal Tumors.

Okamoto K, Watanabe T, Komeda Y, Kono T, Takashima K, Okamoto A, Kono M, Yamada M, Arizumi T, Kamata K, Minaga K, Yamao K, Nagai T, Asakuma Y, Takenaka M, Sakurai T, Matsui S, Nishida N, Chikugo T, Kashida H, Kudo M.

Oncology. 2017;93 Suppl 1:35-42. doi: 10.1159/000481228. Epub 2017 Dec 20.


Evolution of sequence-specific anti-silencing systems in Arabidopsis.

Hosaka A, Saito R, Takashima K, Sasaki T, Fu Y, Kawabe A, Ito T, Toyoda A, Fujiyama A, Tarutani Y, Kakutani T.

Nat Commun. 2017 Dec 18;8(1):2161. doi: 10.1038/s41467-017-02150-7.


Visual assessment of colorectal flat and depressed lesions by using narrow band imaging.

Nakamura H, Ikematsu H, Osera S, Ito R, Sato D, Minamide T, Okamoto N, Yamamoto Y, Hombu T, Takashima K, Nakajo K, Kadota T, Yoda Y, Hori K, Oono Y, Yano T.

Endosc Int Open. 2017 Dec;5(12):E1284-E1288. doi: 10.1055/s-0043-120992. Epub 2017 Dec 6.


Lessons for reviewing clinical trials using induced pluripotent stem cells: examining the case of a first-in-human trial for age-related macular degeneration.

Takashima K, Inoue Y, Tashiro S, Muto K.

Regen Med. 2018 Mar;13(2):123-128. doi: 10.2217/rme-2017-0130. Epub 2017 Dec 6. No abstract available.


A review of Vietnam's healthcare reform through the Direction of Healthcare Activities (DOHA).

Takashima K, Wada K, Tra TT, Smith DR.

Environ Health Prev Med. 2017 Oct 30;22(1):74. doi: 10.1186/s12199-017-0682-z. Review.


DNAJB1/HSP40 Suppresses Melanoma Differentiation-Associated Gene 5-Mitochondrial Antiviral Signaling Protein Function in Conjunction with HSP70.

Takashima K, Oshiumi H, Matsumoto M, Seya T.

J Innate Immun. 2018;10(1):44-55. doi: 10.1159/000480740. Epub 2017 Oct 26.


The TLR3/TICAM-1 signal constitutively controls spontaneous polyposis through suppression of c-Myc in Apc Min/+ mice.

Ono J, Shime H, Takaki H, Takashima K, Funami K, Yoshida S, Takeda Y, Matsumoto M, Kasahara M, Seya T.

J Biomed Sci. 2017 Oct 17;24(1):79. doi: 10.1186/s12929-017-0387-z.


Composition of the microbiota in forestomach fluids and feces of Japanese Black calves with white scours.

Nakamura SI, Kim YH, Takashima K, Kimura A, Nagai K, Ichijo T, Sato S.

J Anim Sci. 2017 Sep;95(9):3949-3960. doi: 10.2527/jas2017.1431.


Fundamental study on a gene transfection methodology for mammalian cells using water-in-oil droplet deformation in a DC electric field.

Kurita H, Takao Y, Kishikawa K, Takashima K, Numano R, Mizuno A.

Biochem Biophys Rep. 2016 Aug 12;8:81-88. doi: 10.1016/j.bbrep.2016.08.001. eCollection 2016 Dec.


Evolution of the degradation mechanism of pure zinc stent in the one-year study of rabbit abdominal aorta model.

Yang H, Wang C, Liu C, Chen H, Wu Y, Han J, Jia Z, Lin W, Zhang D, Li W, Yuan W, Guo H, Li H, Yang G, Kong D, Zhu D, Takashima K, Ruan L, Nie J, Li X, Zheng Y.

Biomaterials. 2017 Nov;145:92-105. doi: 10.1016/j.biomaterials.2017.08.022. Epub 2017 Aug 16.


Cost analysis of leuprorelin acetate in Japanese pre-menopausal breast-cancer patients: comparison between 6-month and 3-month depot formulations.

Goto R, Uda A, Hiroi S, Iwasaki K, Takashima K, Kurebayashi J.

J Med Econ. 2017 Nov;20(11):1163-1169. doi: 10.1080/13696998.2017.1364647. Epub 2017 Aug 16.


Cost analysis of leuprorelin acetate in Japanese prostate cancer patients: comparison between 6-month and 3-month depot formulations.

Goto R, Uda A, Hiroi S, Iwasaki K, Takashima K, Oya M.

J Med Econ. 2017 Nov;20(11):1155-1162. doi: 10.1080/13696998.2017.1362410. Epub 2017 Aug 16.


The LexA transcription factor regulates fatty acid biosynthetic genes in the cyanobacterium Synechocystis sp. PCC 6803.

Kizawa A, Kawahara A, Takashima K, Takimura Y, Nishiyama Y, Hihara Y.

Plant J. 2017 Oct;92(2):189-198. doi: 10.1111/tpj.13644. Epub 2017 Aug 21.


Discovery and informing research participants of incidental findings detected in brain magnetic resonance imaging studies: Review and multi-institutional study.

Takashima K, Takimoto Y, Nakazawa E, Hayashi Y, Tsuchiya A, Fujita M, Akabayashi A.

Brain Behav. 2017 Mar 29;7(5):e00676. doi: 10.1002/brb3.676. eCollection 2017 May. Review.


Gas-liquid interfacial plasmas producing reactive species for cell membrane permeabilization.

Kaneko T, Sasaki S, Takashima K, Kanzaki M.

J Clin Biochem Nutr. 2017 Jan;60(1):3-11. doi: 10.3164/jcbn.16-73. Epub 2016 Dec 17. Review.


Establishment of a rat model of thrombosis induced by intravenous injection of anti-phosphatidylserine-prothrombin complex antibody.

Yamada M, Kawakami T, Takashima K, Nishioka Y, Nishibata Y, Masuda S, Yoshida S, Tomaru U, Ishizu A.

Rheumatology (Oxford). 2017 Jun 1;56(6):1013-1018. doi: 10.1093/rheumatology/kew477.


STING in tumor and host cells cooperatively work for NK cell-mediated tumor growth retardation.

Takashima K, Takeda Y, Oshiumi H, Shime H, Okabe M, Ikawa M, Matsumoto M, Seya T.

Biochem Biophys Res Commun. 2016 Sep 30;478(4):1764-71. doi: 10.1016/j.bbrc.2016.09.021. Epub 2016 Sep 5.


Modulation of electrical potential and conductivity in an atomic-layer semiconductor heterojunction.

Kobayashi Y, Yoshida S, Sakurada R, Takashima K, Yamamoto T, Saito T, Konabe S, Taniguchi T, Watanabe K, Maniwa Y, Takeuchi O, Shigekawa H, Miyata Y.

Sci Rep. 2016 Aug 12;6:31223. doi: 10.1038/srep31223.


Design of small-size pouch motors for rat gait rehabilitation device.

Shih-Yin Chang, Takashima K, Nishikawa S, Niiyama R, Someya T, Onodera H, Kuniyoshi Y.

Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:4578-81. doi: 10.1109/EMBC.2015.7319413.


RIOK3 keeps MDA5 inactive.

Takashima K, Oshiumi H, Seya T.

Oncotarget. 2015 Oct 13;6(31):30423-4. doi: 10.18632/oncotarget.5265. No abstract available.


Recurrent haemarthroses after bilateral total knee arthroplasty for rheumatoid arthritis.

Ohsawa S, Takashima K, Shibuya T, Yamamoto H.

Scand J Rheumatol. 2016 Jan;45(1):85-86. doi: 10.3109/03009742.2015.1085086. Epub 2015 Sep 24. No abstract available.


Adjuvant for vaccine immunotherapy of cancer--focusing on Toll-like receptor 2 and 3 agonists for safely enhancing antitumor immunity.

Seya T, Shime H, Takeda Y, Tatematsu M, Takashima K, Matsumoto M.

Cancer Sci. 2015 Dec;106(12):1659-68. doi: 10.1111/cas.12824. Epub 2015 Nov 18. Review.


COPI-mediated retrieval of SCAP is crucial for regulating lipogenesis under basal and sterol-deficient conditions.

Takashima K, Saitoh A, Funabashi T, Hirose S, Yagi C, Nozaki S, Sato R, Shin HW, Nakayama K.

J Cell Sci. 2015 Aug 1;128(15):2805-15. doi: 10.1242/jcs.164137. Epub 2015 Jun 19.


Genome-wide negative feedback drives transgenerational DNA methylation dynamics in Arabidopsis.

Ito T, Tarutani Y, To TK, Kassam M, Duvernois-Berthet E, Cortijo S, Takashima K, Saze H, Toyoda A, Fujiyama A, Colot V, Kakutani T.

PLoS Genet. 2015 Apr 22;11(4):e1005154. doi: 10.1371/journal.pgen.1005154. eCollection 2015 Apr.


RIOK3-mediated phosphorylation of MDA5 interferes with its assembly and attenuates the innate immune response.

Takashima K, Oshiumi H, Takaki H, Matsumoto M, Seya T.

Cell Rep. 2015 Apr 14;11(2):192-200.


Deubiquitinating enzymes regulate Hes1 stability and neuronal differentiation.

Kobayashi T, Iwamoto Y, Takashima K, Isomura A, Kosodo Y, Kawakami K, Nishioka T, Kaibuchi K, Kageyama R.

FEBS J. 2015 Jul;282(13):2411-23. doi: 10.1111/febs.13290. Epub 2015 Apr 23.


[Toxicology in small animal clinical medicine].

Takashima K.

Chudoku Kenkyu. 2014 Dec;27(4):299-306. Review. Japanese. No abstract available.


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