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Prognostic Value of Primary Tumor Sidedness for Unresectable Stage IV Colorectal Cancer: A Retrospective Study.

Shida D, Tanabe T, Boku N, Takashima A, Yoshida T, Tsukamoto S, Kanemitsu Y.

Ann Surg Oncol. 2019 Feb 4. doi: 10.1245/s10434-019-07209-x. [Epub ahead of print]


Association between UGT1A1 gene polymorphism and safety and efficacy of irinotecan monotherapy as the third-line treatment for advanced gastric cancer.

Yamaguchi T, Iwasa S, Shoji H, Honma Y, Takashima A, Kato K, Hamaguchi T, Higuchi K, Boku N.

Gastric Cancer. 2019 Jan 2. doi: 10.1007/s10120-018-00917-5. [Epub ahead of print]


Iso-α-Acids, the Bitter Components of Beer, Suppress Microglial Inflammation in rTg4510 Tauopathy.

Ano Y, Takaichi Y, Uchida K, Kondo K, Nakayama H, Takashima A.

Molecules. 2018 Nov 29;23(12). pii: E3133. doi: 10.3390/molecules23123133.


The relationship between torso inclination and the shearing force of the buttocks while seated in a wheelchair: Preliminary research in non-disabled individuals.

Shirogane S, Toyama S, Takashima A, Tanaka T.

Assist Technol. 2018 Nov 30:1-7. doi: 10.1080/10400435.2018.1547333. [Epub ahead of print]


Primary Tumor Resection for Stage IV Colorectal Cancer in the Era of Targeted Chemotherapy.

Shida D, Boku N, Tanabe T, Yoshida T, Tsukamoto S, Takashima A, Kanemitsu Y.

J Gastrointest Surg. 2018 Nov 27. doi: 10.1007/s11605-018-4044-y. [Epub ahead of print]


Cued reactivation during slow-wave sleep induces brain connectivity changes related to memory stabilization.

Berkers RMWJ, Ekman M, van Dongen EV, Takashima A, Barth M, Paller KA, Fernández G.

Sci Rep. 2018 Nov 16;8(1):16958. doi: 10.1038/s41598-018-35287-6.


Dysregulation of autophagy and stress granule-related proteins in stress-driven Tau pathology.

Silva JM, Rodrigues S, Sampaio-Marques B, Gomes P, Neves-Carvalho A, Dioli C, Soares-Cunha C, Mazuik BF, Takashima A, Ludovico P, Wolozin B, Sousa N, Sotiropoulos I.

Cell Death Differ. 2018 Nov 15. doi: 10.1038/s41418-018-0217-1. [Epub ahead of print]


Distribution of endogenous normal tau in the mouse brain.

Kubo A, Misonou H, Matsuyama M, Nomori A, Wada-Kakuda S, Takashima A, Kawata M, Murayama S, Ihara Y, Miyasaka T.

J Comp Neurol. 2019 Apr 1;527(5):985-998. doi: 10.1002/cne.24577. Epub 2018 Dec 5.


Instrumental evaluation sensitively detects subclinical skin changes by the epidermal growth factor receptor inhibitors and risk factors for severe acneiform eruption.

Kikuchi K, Nozawa K, Yamazaki N, Nakai Y, Higashiyama A, Asano M, Fujiwara Y, Kanda S, Ohe Y, Takashima A, Boku N, Inoue A, Takahashi M, Mori T, Taguchi O, Inoue Y, Mizutani H.

J Dermatol. 2019 Jan;46(1):18-25. doi: 10.1111/1346-8138.14691. Epub 2018 Nov 7.


Clinical outcomes of patients with G1/G2 neuroendocrine tumors arising from foregut or hindgut treated with somatostatin analogs: a retrospective study.

Ida H, Honma Y, Hirano H, Shoji H, Iwasa S, Okita N, Takashima A, Kato K, Fukuda T, Boku N.

Invest New Drugs. 2018 Sep 28. doi: 10.1007/s10637-018-0669-7. [Epub ahead of print]


Local cyclical compression modulates macrophage function in situ and alleviates immobilization-induced muscle atrophy.

Saitou K, Tokunaga M, Yoshino D, Sakitani N, Maekawa T, Ryu Y, Nagao M, Nakamoto H, Saito T, Kawanishi N, Suzuki K, Ogata T, Makuuchi M, Takashima A, Sawada K, Kawamura S, Nakazato K, Kouzaki K, Harada I, Ichihara Y, Sawada Y.

Clin Sci (Lond). 2018 Oct 12;132(19):2147-2161. doi: 10.1042/CS20180432. Print 2018 Oct 15. Erratum in: Clin Sci (Lond). 2019 Feb 5;133(3):407.


Neural Entrainment Determines the Words We Hear.

Kösem A, Bosker HR, Takashima A, Meyer A, Jensen O, Hagoort P.

Curr Biol. 2018 Sep 24;28(18):2867-2875.e3. doi: 10.1016/j.cub.2018.07.023. Epub 2018 Sep 6.


Novel lactopeptides in fermented dairy products improve memory function and cognitive decline.

Ano Y, Ayabe T, Kutsukake T, Ohya R, Takaichi Y, Uchida S, Yamada K, Uchida K, Takashima A, Nakayama H.

Neurobiol Aging. 2018 Dec;72:23-31. doi: 10.1016/j.neurobiolaging.2018.07.016. Epub 2018 Aug 6.


Role of Predictive Value of the Modified Glasgow Prognostic Score for Later-line Chemotherapy in Patients With Metastatic Colorectal Cancer.

Tsuchihashi K, Ito M, Moriwaki T, Fukuoka S, Taniguchi H, Takashima A, Kumekawa Y, Kajiwara T, Yamazaki K, Esaki T, Makiyama A, Denda T, Satake H, Suto T, Sugimoto N, Katsumata K, Ishikawa T, Kashiwada T, Oki E, Komatsu Y, Okuyama H, Sakai D, Ueno H, Tamura T, Yamashita K, Kishimoto J, Shimada Y, Baba E.

Clin Colorectal Cancer. 2018 Dec;17(4):e687-e697. doi: 10.1016/j.clcc.2018.07.004. Epub 2018 Jul 29.


Deposition of Phosphorylated α-Synuclein in the rTg4510 Mouse Model of Tauopathy.

Takaichi Y, Ano Y, Chambers JK, Uchida K, Takashima A, Nakayama H.

J Neuropathol Exp Neurol. 2018 Oct 1;77(10):920-928. doi: 10.1093/jnen/nly070.


A pilot study towards long-term thermal comfort research for lower-limb prosthesis wearers.

Williams RJ, Takashima A, Ogata T, Holloway C.

Prosthet Orthot Int. 2018 Aug 6:309364618791604. doi: 10.1177/0309364618791604. [Epub ahead of print]


Promotion and suppression of autobiographical thinking differentially affect episodic memory consolidation.

Varma S, Daselaar SM, Kessels RPC, Takashima A.

PLoS One. 2018 Aug 3;13(8):e0201780. doi: 10.1371/journal.pone.0201780. eCollection 2018.


A case of scarred uterine rupture at 11 weeks of gestation having a uterine scar places induced by in vitro fertilization-embryo transfer.

Takashima A, Takeshita N, Kinoshita T.

Clin Pract. 2018 May 10;8(2):1038. doi: 10.4081/cp.2018.1038. eCollection 2018 Mar 28.


Retrospective Analyses of Systemic Chemotherapy and Cytoreductive Surgery for Patients with Ovarian Metastases from Colorectal Cancer: A Single-Center Experience.

Sekine K, Hamaguchi T, Shoji H, Takashima A, Honma Y, Iwasa S, Kato K, Takahashi K, Kato T, Kanemitsu Y, Boku N.

Oncology. 2018;95(4):220-228. doi: 10.1159/000489665. Epub 2018 Jul 20.


Adult dyslexic readers benefit less from visual input during audiovisual speech processing: fMRI evidence.

Francisco AA, Takashima A, McQueen JM, van den Bunt M, Jesse A, Groen MA.

Neuropsychologia. 2018 Aug;117:454-471. doi: 10.1016/j.neuropsychologia.2018.07.009. Epub 2018 Jul 7.


Uterine rupture due to placenta percreta in the first trimester of a pregnancy subsequent to a transverse uterine fundal cesarean section: A case report.

Ishida H, Takashima A, Nagaoka M, Takeshita N, Kinoshita T.

J Obstet Gynaecol Res. 2018 Sep;44(9):1832-1835. doi: 10.1111/jog.13699. Epub 2018 Jul 5.


Imaging peritoneal metastasis of gastric cancer with 18F-fluorothymidine positron emission tomography/computed tomography: a proof-of-concept study.

Honma Y, Terauchi T, Tateishi U, Kano D, Nagashima K, Shoji H, Iwasa S, Takashima A, Kato K, Hamaguchi T, Boku N, Shimada Y, Yamada Y.

Br J Radiol. 2018 Sep;91(1089):20180259. doi: 10.1259/bjr.20180259. Epub 2018 Jun 27.


Peritoneal metastasis as a predictive factor for nab-paclitaxel in patients with pretreated advanced gastric cancer: an exploratory analysis of the phase III ABSOLUTE trial.

Takashima A, Shitara K, Fujitani K, Koeda K, Hara H, Nakayama N, Hironaka S, Nishikawa K, Kimura Y, Amagai K, Fujii H, Muro K, Esaki T, Choda Y, Takano T, Chin K, Sato A, Goto M, Fukushima N, Hara T, Machida N, Ohta M, Boku N, Shimura M, Morita S, Koizumi W.

Gastric Cancer. 2019 Jan;22(1):155-163. doi: 10.1007/s10120-018-0838-6. Epub 2018 May 31.


Frontotemporal dementia with Parkinsonism linked to chromosome-17 mutations enhance tau oligomer formation.

Maeda S, Sato Y, Takashima A.

Neurobiol Aging. 2018 Sep;69:26-32. doi: 10.1016/j.neurobiolaging.2018.04.014. Epub 2018 May 7.


Survival impact of post-progression chemotherapy in advanced gastric cancer: systematic review and meta-analysis.

Iizumi S, Takashima A, Sakamaki K, Morita S, Boku N.

Cancer Chemother Pharmacol. 2018 Jun;81(6):981-989. doi: 10.1007/s00280-018-3569-9. Epub 2018 Mar 29.


Shorter survival in adolescent and young adult patients, compared to adult patients, with stage IV colorectal cancer in Japan.

Shida D, Ahiko Y, Tanabe T, Yoshida T, Tsukamoto S, Ochiai H, Takashima A, Boku N, Kanemitsu Y.

BMC Cancer. 2018 Mar 27;18(1):334. doi: 10.1186/s12885-018-4241-9.


Knee extensor strength assessed using a vertical squat and a simple geometric model to calculate joint torque: An evaluation of validity and clinical utility.

Sato H, Kusayanagi K, Kondo Y, Kamide N, Shiba Y, Takashima A.

Geriatr Gerontol Int. 2018 Jul;18(7):1125-1131. doi: 10.1111/ggi.13299. Epub 2018 Mar 24.


Tau Depletion in APP Transgenic Mice Attenuates Task-Related Hyperactivation of the Hippocampus and Differentially Influences Locomotor Activity and Spatial Memory.

Yoshikawa M, Soeda Y, Michikawa M, Almeida OFX, Takashima A.

Front Neurosci. 2018 Mar 1;12:124. doi: 10.3389/fnins.2018.00124. eCollection 2018.


Type of second primary malignancy after achieving complete response by definitive chemoradiation therapy in patients with esophageal squamous cell carcinoma.

Yamaguchi T, Kato K, Nagashima K, Iwasa S, Honma Y, Takashima A, Hamaguchi T, Ito Y, Itami J, Boku N, Higuchi K.

Int J Clin Oncol. 2018 Aug;23(4):652-658. doi: 10.1007/s10147-018-1258-7. Epub 2018 Mar 8.


Theta-band Oscillations in the Middle Temporal Gyrus Reflect Novel Word Consolidation.

Bakker-Marshall I, Takashima A, Schoffelen JM, van Hell JG, Janzen G, McQueen JM.

J Cogn Neurosci. 2018 May;30(5):621-633. doi: 10.1162/jocn_a_01240. Epub 2018 Feb 2.


A retrospective analysis of 5-fluorouracil plus cisplatin as first-line chemotherapy in the recent treatment strategy for patients with metastatic or recurrent esophageal squamous cell carcinoma.

Hiramoto S, Kato K, Shoji H, Okita N, Takashima A, Honma Y, Iwasa S, Hamaguchi T, Yamada Y, Shimada Y, Boku N.

Int J Clin Oncol. 2018 Jun;23(3):466-472. doi: 10.1007/s10147-018-1239-x. Epub 2018 Jan 20.


A phase II study of nab-paclitaxel in combination with ramucirumab in patients with previously treated advanced gastric cancer.

Bando H, Shimodaira H, Fujitani K, Takashima A, Yamaguchi K, Nakayama N, Takahashi T, Oki E, Azuma M, Nishina T, Hironaka S, Komatsu Y, Shitara K.

Eur J Cancer. 2018 Mar;91:86-91. doi: 10.1016/j.ejca.2017.11.032. Epub 2018 Jan 30.


Pregnancy outcomes after assisted reproductive procedures with embryos that had been derived from affected and unaffected ovaries among women with small unilateral endometriomas.

Takashima A, Takeshita N, Kinoshita T.

Reprod Med Biol. 2017 Mar 22;16(2):152-156. doi: 10.1002/rmb2.12020. eCollection 2017 Apr.


Distinguishable memory retrieval networks for collaboratively and non-collaboratively learned information.

Vanlangendonck F, Takashima A, Willems RM, Hagoort P.

Neuropsychologia. 2018 Mar;111:123-132. doi: 10.1016/j.neuropsychologia.2017.12.008. Epub 2017 Dec 6.


The peripheral immune status of granulocytic myeloid-derived suppressor cells correlates the survival in advanced gastric cancer patients receiving cisplatin-based chemotherapy.

Shoji H, Tada K, Kitano S, Nishimura T, Shimada Y, Nagashima K, Aoki K, Hiraoka N, Honma Y, Iwasa S, Takashima A, Kato K, Boku N, Honda K, Yamada T, Heike Y, Hamaguchi T.

Oncotarget. 2017 May 30;8(56):95083-95094. doi: 10.18632/oncotarget.18297. eCollection 2017 Nov 10.


A Prospective, Multicenter Phase II Study of the Efficacy and Feasibility of 15-minute Panitumumab Infusion Plus Irinotecan for Oxaliplatin- and Irinotecan-refractory, KRAS Wild-type Metastatic Colorectal Cancer (Short Infusion of Panitumumab Trial).

Akiyoshi K, Hamaguchi T, Yoshimura K, Takahashi N, Honma Y, Iwasa S, Takashima A, Kato K, Yamada Y, Onodera H, Takeshita S, Yasui H, Sakai G, Akatsuka S, Ogawa K, Horita Y, Nagai Y, Shimada Y.

Clin Colorectal Cancer. 2018 Mar;17(1):e83-e89. doi: 10.1016/j.clcc.2017.10.004. Epub 2017 Oct 16.


Disentangling the prognostic heterogeneity of stage III colorectal cancer through histologic stromal categorization.

Ueno H, Sekine S, Oshiro T, Kanemitsu Y, Hamaguchi T, Shida D, Takashima A, Ishiguro M, Ito E, Hashiguchi Y, Kondo F, Shimazaki H, Mochizuki S, Kajiwara Y, Shinto E, Yamamoto J, Shimada Y.

Surgery. 2018 Apr;163(4):777-783. doi: 10.1016/j.surg.2017.09.007. Epub 2017 Nov 20.


Patterns of Relapse after Definitive Chemoradiotherapy in Stage II/III (Non-T4) Esophageal Squamous Cell Carcinoma.

Sudo K, Kato K, Kuwabara H, Sasaki Y, Takahashi N, Shoji H, Iwasa S, Honma Y, Okita NT, Takashima A, Hamaguchi T, Yamada Y, Ito Y, Itami J, Fukuda T, Tobinai K, Boku N.

Oncology. 2018;94(1):47-54. doi: 10.1159/000480515. Epub 2017 Oct 28.


Characterization of the pierce two-node model under exercise load by parameter optimization toward construction of a modified thermal model for persons with spinal cord injury.

Takizawa K, Suzurikawa J, Higuchi Y, Huang Ming, Tamura T, Kurabayashi D, Inoue T, Ogata T, Takashima A.

Conf Proc IEEE Eng Med Biol Soc. 2017 Jul;2017:2466-2469. doi: 10.1109/EMBC.2017.8037356.


Construction of a soft wearable body cooling system for persons with spinal cord injury.

Takashima A, Sato K, Takizawa K, Suzurikawa J, Higuchi Y, Huang M, Teshima Y, Tamura T, Kurabayashi D, Inoue T, Ogata T.

Conf Proc IEEE Eng Med Biol Soc. 2017 Jul;2017:913-916. doi: 10.1109/EMBC.2017.8036973.


Propensity Score Analysis of Regorafenib Versus Trifluridine/Tipiracil in Patients with Metastatic Colorectal Cancer Refractory to Standard Chemotherapy (REGOTAS): A Japanese Society for Cancer of the Colon and Rectum Multicenter Observational Study.

Moriwaki T, Fukuoka S, Taniguchi H, Takashima A, Kumekawa Y, Kajiwara T, Yamazaki K, Esaki T, Makiyama C, Denda T, Satake H, Suto T, Sugimoto N, Enomoto M, Ishikawa T, Kashiwada T, Sugiyama M, Komatsu Y, Okuyama H, Baba E, Sakai D, Watanabe T, Tamura T, Yamashita K, Gosho M, Shimada Y.

Oncologist. 2018 Jan;23(1):7-15. doi: 10.1634/theoncologist.2017-0275. Epub 2017 Sep 11.


Impact of hysteroscopic surgery for isthmocele associated with cesarean scar syndrome.

Tsuji S, Kimura F, Yamanaka A, Hanada T, Hirata K, Takebayashi A, Takashima A, Seko-Nitta A, Murakami T.

J Obstet Gynaecol Res. 2018 Jan;44(1):43-48. doi: 10.1111/jog.13464. Epub 2017 Sep 11.


Polyunsaturated fatty acid deficiency during neurodevelopment in mice models the prodromal state of schizophrenia through epigenetic changes in nuclear receptor genes.

Maekawa M, Watanabe A, Iwayama Y, Kimura T, Hamazaki K, Balan S, Ohba H, Hisano Y, Nozaki Y, Ohnishi T, Toyoshima M, Shimamoto C, Iwamoto K, Bundo M, Osumi N, Takahashi E, Takashima A, Yoshikawa T.

Transl Psychiatry. 2017 Sep 5;7(9):e1229. doi: 10.1038/tp.2017.182.


A phase II study of combination therapy with oral S-1 and cisplatin in elderly patients with advanced gastric cancer.

Sasaki Y, Iwasa S, Okazaki S, Goto M, Kojima Y, Naganuma A, Nagashima K, Nagai Y, Hirano H, Honma Y, Takashima A, Kato K, Hamaguchi T.

Gastric Cancer. 2018 May;21(3):439-445. doi: 10.1007/s10120-017-0753-2. Epub 2017 Aug 1.


Mutation-induced loss of APP function causes GABAergic depletion in recessive familial Alzheimer's disease: analysis of Osaka mutation-knockin mice.

Umeda T, Kimura T, Yoshida K, Takao K, Fujita Y, Matsuyama S, Sakai A, Yamashita M, Yamashita Y, Ohnishi K, Suzuki M, Takuma H, Miyakawa T, Takashima A, Morita T, Mori H, Tomiyama T.

Acta Neuropathol Commun. 2017 Jul 31;5(1):59. doi: 10.1186/s40478-017-0461-5.


Efficacy and safety of taxane monotherapy in advanced gastric cancer refractory to triplet chemotherapy with docetaxel, cisplatin, and S-1: a multicenter retrospective study.

Iizumi S, Takashima A, Narita Y, Tajika M, Muro K, Kawai S, Yasui H, Matsushima T, Takahari D, Nagashima K, Boku N.

Cancer Chemother Pharmacol. 2017 Sep;80(3):575-582. doi: 10.1007/s00280-017-3397-3. Epub 2017 Jul 20.


α-Glucosidase inhibitor miglitol attenuates glucose fluctuation, heart rate variability and sympathetic activity in patients with type 2 diabetes and acute coronary syndrome: a multicenter randomized controlled (MACS) study.

Shimabukuro M, Tanaka A, Sata M, Dai K, Shibata Y, Inoue Y, Ikenaga H, Kishimoto S, Ogasawara K, Takashima A, Niki T, Arasaki O, Oshiro K, Mori Y, Ishihara M, Node K; Collaborators on the Effect of Miglitol on Glucose Metabolism in Acute Coronary Syndrome (MACS) Study.

Cardiovasc Diabetol. 2017 Jul 6;16(1):86. doi: 10.1186/s12933-017-0571-1.


Clinical Outcomes of Resectable Esophageal Cancer with Supraclavicular Lymph Node Metastases Treated with Curative Intent.

Honma Y, Hokamura N, Nagashima K, Sudo K, Shoji H, Iwasa S, Takashima A, Kato K, Hamaguchi T, Boku N, Umezawa R, Ito Y, Itami J, Koyanagi K, Igaki H, Tachimori Y.

Anticancer Res. 2017 Jul;37(7):3741-3749.


Esophageal Metastasis from Rectal Cancer Successfully Treated with Fluorouracil-Based Chemotherapy with Bevacizumab: A Case Report and Review of the Literature.

Watanabe S, Takashima A, Taniguchi H, Tanaka Y, Nakamura S, Okita N, Honma Y, Iwasa S, Kato K, Hamaguchi T, Boku N.

Case Rep Oncol. 2017 May 5;10(2):407-415. doi: 10.1159/000474939. eCollection 2017 May-Aug.


Local Somatodendritic Translation and Hyperphosphorylation of Tau Protein Triggered by AMPA and NMDA Receptor Stimulation.

Kobayashi S, Tanaka T, Soeda Y, Almeida OFX, Takashima A.

EBioMedicine. 2017 Jun;20:120-126. doi: 10.1016/j.ebiom.2017.05.012. Epub 2017 May 17.

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