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Items: 26


Retraction: The E3-ligase E6AP Represses Breast Cancer Metastasis via Regulation of ECT2-Rho Signaling.

Mansour M, Haupt S, Chan AL, Godde N, Rizzitelli A, Loi S, Caramia F, Deb S, Takano EA, Bishton M, Johnstone C, Monahan B, Levav-Cohen Y, Jiang YH, Yap AS, Fox S, Bernard O, Anderson R, Haupt Y.

Cancer Res. 2019 Jun 1;79(11):3008. doi: 10.1158/0008-5472.CAN-19-1133. No abstract available.


LRH-1 expression patterns in breast cancer tissues are associated with tumour aggressiveness.

Pang JB, Molania R, Chand A, Knower K, Takano EA, Byrne DJ, Mikeska T, Millar EKA, Lee CS, O'Toole SA, Clyne C, Gorringe KL, Dobrovic A, Fox SB.

Oncotarget. 2017 Jul 28;8(48):83626-83636. doi: 10.18632/oncotarget.18886. eCollection 2017 Oct 13.


Genome-wide functional analysis reveals central signaling regulators of lymphatic endothelial cell migration and remodeling.

Williams SP, Odell AF, Karnezis T, Farnsworth RH, Gould CM, Li J, Paquet-Fifield S, Harris NC, Walter A, Gregory JL, Lamont SF, Liu R, Takano EA, Nowell CJ, Bower NI, Resnick D, Smyth GK, Coultas L, Hogan BM, Fox SB, Mueller SN, Simpson KJ, Achen MG, Stacker SA.

Sci Signal. 2017 Oct 3;10(499). pii: eaal2987. doi: 10.1126/scisignal.aal2987.


BRCA2 carriers with male breast cancer show elevated tumour methylation.

Deb S, Gorringe KL, Pang JB, Byrne DJ, Takano EA, Investigators K, Dobrovic A, Fox SB.

BMC Cancer. 2017 Sep 11;17(1):641. doi: 10.1186/s12885-017-3632-7.


Breast ductal carcinoma in situ carry mutational driver events representative of invasive breast cancer.

Pang JB, Savas P, Fellowes AP, Mir Arnau G, Kader T, Vedururu R, Hewitt C, Takano EA, Byrne DJ, Choong DY, Millar EK, Lee CS, O'Toole SA, Lakhani SR, Cummings MC, Mann GB, Campbell IG, Dobrovic A, Loi S, Gorringe KL, Fox SB.

Mod Pathol. 2017 Jul;30(7):952-963. doi: 10.1038/modpathol.2017.21. Epub 2017 Mar 24.


GATA3 expression in triple-negative breast cancers.

Byrne DJ, Deb S, Takano EA, Fox SB.

Histopathology. 2017 Jul;71(1):63-71. doi: 10.1111/his.13187. Epub 2017 Apr 19.


MDM4 is a rational target for treating breast cancers with mutant p53.

Miranda PJ, Buckley D, Raghu D, Pang JB, Takano EA, Vijayakumaran R, Teunisse AF, Posner A, Procter T, Herold MJ, Gamell C, Marine JC, Fox SB, Jochemsen A, Haupt S, Haupt Y.

J Pathol. 2017 Apr;241(5):661-670. doi: 10.1002/path.4877. Epub 2017 Mar 1.


The E3-ligase E6AP Represses Breast Cancer Metastasis via Regulation of ECT2-Rho Signaling.

Mansour M, Haupt S, Chan AL, Godde N, Rizzitelli A, Loi S, Caramia F, Deb S, Takano EA, Bishton M, Johnstone C, Monahan B, Levav-Cohen Y, Jiang YH, Yap AS, Fox S, Bernard O, Anderson R, Haupt Y.

Cancer Res. 2016 Jul 15;76(14):4236-48. doi: 10.1158/0008-5472.CAN-15-1553. Epub 2016 May 26. Retraction in: Cancer Res. 2019 Jun 1;79(11):3008.


Assessment of DNA methylation profiling and copy number variation as indications of clonal relationship in ipsilateral and contralateral breast cancers to distinguish recurrent breast cancer from a second primary tumour.

Huang KT, Mikeska T, Li J, Takano EA, Millar EK, Graham PH, Boyle SE, Campbell IG, Speed TP, Dobrovic A, Fox SB.

BMC Cancer. 2015 Oct 9;15:669. doi: 10.1186/s12885-015-1676-0.


Targeting Mdmx to treat breast cancers with wild-type p53.

Haupt S, Buckley D, Pang JM, Panimaya J, Paul PJ, Gamell C, Takano EA, Lee YY, Hiddingh S, Rogers TM, Teunisse AF, Herold MJ, Marine JC, Fox SB, Jochemsen A, Haupt Y.

Cell Death Dis. 2015 Jul 16;6:e1821. doi: 10.1038/cddis.2015.173.


Breast Tissue Composition and Immunophenotype and Its Relationship with Mammographic Density in Women at High Risk of Breast Cancer.

Pang JM, Byrne DJ, Takano EA, Jene N, Petelin L, McKinley J, Poliness C, Saunders C, Taylor D, Mitchell G, Fox SB.

PLoS One. 2015 Jun 25;10(6):e0128861. doi: 10.1371/journal.pone.0128861. eCollection 2015.


Low-grade fibromatosis-like spindle cell carcinomas of the breast are molecularly exiguous.

Takano EA, Hunter SM, Campbell IG, Fox SB.

J Clin Pathol. 2015 May;68(5):362-7. doi: 10.1136/jclinpath-2014-202824. Epub 2015 Feb 23.


Methylation profiling of ductal carcinoma in situ and its relationship to histopathological features.

Pang JM, Deb S, Takano EA, Byrne DJ, Jene N, Boulghourjian A, Holliday A, Millar E, Lee CS, O'Toole SA, Dobrovic A, Fox SB.

Breast Cancer Res. 2014 Oct 21;16(5):423. doi: 10.1186/s13058-014-0423-9.


Differential mechanisms of CDKN2A (p16) alteration in oral tongue squamous cell carcinomas and correlation with patient outcome.

Lim AM, Do H, Young RJ, Wong SQ, Angel C, Collins M, Takano EA, Corry J, Wiesenfeld D, Kleid S, Sigston E, Lyons B, Fox SB, Rischin D, Dobrovic A, Solomon B.

Int J Cancer. 2014 Aug 15;135(4):887-95. doi: 10.1002/ijc.28727. Epub 2014 Jan 30.


Quantitative methodology is critical for assessing DNA methylation and impacts on correlation with patient outcome.

Lim AM, Candiloro IL, Wong N, Collins M, Do H, Takano EA, Angel C, Young RJ, Corry J, Wiesenfeld D, Kleid S, Sigston E, Lyons B, Rischin D, Solomon B, Dobrovic A.

Clin Epigenetics. 2014 Dec 9;6(1):22. doi: 10.1186/1868-7083-6-22. eCollection 2014.


A fully human inhibitory monoclonal antibody to the Wnt receptor RYK.

Halford MM, Macheda ML, Parish CL, Takano EA, Fox S, Layton D, Nice E, Stacker SA.

PLoS One. 2013 Sep 18;8(9):e75447. doi: 10.1371/journal.pone.0075447. eCollection 2013.


The molecular characterisation of unusual subcutaneous spindle cell lesion of breast.

Takano EA, Rogers TM, Young RJ, Rayoo M, Kostos P, Ferguson R, Campbell IG, Debiec-Rychter M, Fox SB.

J Clin Pathol. 2012 Aug;65(8):746-50. doi: 10.1136/jclinpath-2011-200629. Epub 2012 Apr 20.


Aberrant DNA methylation but not mutation of CITED4 is associated with alteration of HIF-regulated genes in breast cancer.

Huang KT, Takano EA, Mikeska T, Byrne DJ, Dobrovic A, Fox SB.

Breast Cancer Res Treat. 2011 Nov;130(1):319-29. doi: 10.1007/s10549-011-1657-1. Epub 2011 Jul 14.


The Hippo pathway transcriptional co-activator, YAP, is an ovarian cancer oncogene.

Zhang X, George J, Deb S, Degoutin JL, Takano EA, Fox SB; AOCS Study group, Bowtell DD, Harvey KF.

Oncogene. 2011 Jun 23;30(25):2810-22. doi: 10.1038/onc.2011.8. Epub 2011 Feb 14.


A multiplex endpoint RT-PCR assay for quality assessment of RNA extracted from formalin-fixed paraffin-embedded tissues.

Takano EA, Mikeska T, Dobrovic A, Byrne DJ, Fox SB.

BMC Biotechnol. 2010 Dec 17;10:89. doi: 10.1186/1472-6750-10-89.


Nuclear and cytoplasmic expressions of ERβ1 and ERβ2 are predictive of response to therapy and alters prognosis in familial breast cancers.

Yan M, Rayoo M, Takano EA; kConFab Investigators, Fox SB.

Breast Cancer Res Treat. 2011 Apr;126(2):395-405. doi: 10.1007/s10549-010-0941-9. Epub 2010 May 20.


BRCA1 tumours correlate with a HIF-1alpha phenotype and have a poor prognosis through modulation of hydroxylase enzyme profile expression.

Yan M, Rayoo M, Takano EA; KConFab Investigators, Fox SB.

Br J Cancer. 2009 Oct 6;101(7):1168-74. doi: 10.1038/sj.bjc.6605287. Epub 2009 Sep 1. Erratum in: Br J Cancer. 2009 Nov 17;101(10):1806. Thorne, H [removed].


Expression of the forkhead box transcription factor FOXP1 is associated with oestrogen receptor alpha, oestrogen receptor beta and improved survival in familial breast cancers.

Rayoo M, Yan M, Takano EA, Bates GJ, Brown PJ, Banham AH, Fox SB.

J Clin Pathol. 2009 Oct;62(10):896-902. doi: 10.1136/jcp.2009.065169. Epub 2009 Jul 20.


Rapid detection of carriers with BRCA1 and BRCA2 mutations using high resolution melting analysis.

Takano EA, Mitchell G, Fox SB, Dobrovic A.

BMC Cancer. 2008 Feb 25;8:59. doi: 10.1186/1471-2407-8-59.


Temporal regulation of Cre-recombinase activity in Scl-positive neurons of the central nervous system.

Bradley CK, Takano EA, Göthert JR, Göttgens B, Green AR, Begley CG, van Eekelen JA.

Genesis. 2007 Mar;45(3):145-51.


The essential haematopoietic transcription factor Scl is also critical for neuronal development.

Bradley CK, Takano EA, Hall MA, Göthert JR, Harvey AR, Begley CG, van Eekelen JA.

Eur J Neurosci. 2006 Apr;23(7):1677-89.


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