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Items: 42


Nutritional Heterogeneity Among Aspergillus fumigatus Strains Has Consequences for Virulence in a Strain- and Host-Dependent Manner.

Ries LNA, Steenwyk JL, de Castro PA, de Lima PBA, Almeida F, de Assis LJ, Manfiolli AO, Takahashi-Nakaguchi A, Kusuya Y, Hagiwara D, Takahashi H, Wang X, Obar JJ, Rokas A, Goldman GH.

Front Microbiol. 2019 Apr 24;10:854. doi: 10.3389/fmicb.2019.00854. eCollection 2019.


A Transcriptomics Approach To Unveiling the Mechanisms of In Vitro Evolution towards Fluconazole Resistance of a Candida glabrata Clinical Isolate.

Cavalheiro M, Costa C, Silva-Dias A, Miranda IM, Wang C, Pais P, Pinto SN, Mil-Homens D, Sato-Okamoto M, Takahashi-Nakaguchi A, Silva RM, Mira NP, Fialho AM, Chibana H, Rodrigues AG, Butler G, Teixeira MC.

Antimicrob Agents Chemother. 2018 Dec 21;63(1). pii: e00995-18. doi: 10.1128/AAC.00995-18. Print 2019 Jan.


[Investigation of Virulence Factors by "Omics" Approaches].

Takahashi-Nakaguchi A, Hagiwara D, Takahashi H, Sakai K, Toyotome T, Watanabe A, Kamei K, Gonoi T.

Med Mycol J. 2018;59(2):J35-J40. doi: 10.3314/mmj.18.005. Review. Japanese.


Clinical and Bacteriologic Analysis of Nontypeable Haemophilus influenzae Strains Isolated from Children with Invasive Diseases in Japan from 2008 to 2015.

Naito S, Takeuchi N, Ohkusu M, Takahashi-Nakaguchi A, Takahashi H, Imuta N, Nishi J, Shibayama K, Matsuoka M, Sasaki Y, Ishiwada N.

J Clin Microbiol. 2018 Jun 25;56(7). pii: e00141-18. doi: 10.1128/JCM.00141-18. Print 2018 Jul.


Cooperation between ER stress and calcineurin signaling contributes to the maintenance of cell wall integrity in Candida glabrata.

Tanaka Y, Sasaki M, Ito F, Aoyama T, Sato-Okamoto M, Takahashi-Nakaguchi A, Chibana H, Shibata N.

Fungal Biol. 2018 Jan;122(1):19-33. doi: 10.1016/j.funbio.2017.09.007. Epub 2017 Oct 12.


Global gene expression reveals stress-responsive genes in Aspergillus fumigatus mycelia.

Takahashi H, Kusuya Y, Hagiwara D, Takahashi-Nakaguchi A, Sakai K, Gonoi T.

BMC Genomics. 2017 Dec 4;18(1):942. doi: 10.1186/s12864-017-4316-z.


A New Determinant of Candida glabrata Virulence: The Acetate Exporter CgDtr1.

Romão D, Cavalheiro M, Mil-Homens D, Santos R, Pais P, Costa C, Takahashi-Nakaguchi A, Fialho AM, Chibana H, Teixeira MC.

Front Cell Infect Microbiol. 2017 Nov 14;7:473. doi: 10.3389/fcimb.2017.00473. eCollection 2017.


Aspergillus fumigatus adhesion factors in dormant conidia revealed through comparative phenotypic and transcriptomic analyses.

Takahashi-Nakaguchi A, Sakai K, Takahashi H, Hagiwara D, Toyotome T, Chibana H, Watanabe A, Yaguchi T, Yamaguchi M, Kamei K, Gonoi T.

Cell Microbiol. 2018 Mar;20(3). doi: 10.1111/cmi.12802. Epub 2017 Dec 22.


Comparative genomic and transcriptomic analyses unveil novel features of azole resistance and adaptation to the human host in Candida glabrata.

Salazar SB, Wang C, Münsterkötter M, Okamoto M, Takahashi-Nakaguchi A, Chibana H, Lopes MM, Güldener U, Butler G, Mira NP.

FEMS Yeast Res. 2018 Feb 1;18(1). doi: 10.1093/femsyr/fox079.


Fungus-derived hydroxyl radicals kill hepatic cells by enhancing nuclear transglutaminase.

Shrestha R, Shrestha R, Qin XY, Kuo TF, Oshima Y, Iwatani S, Teraoka R, Fujii K, Hara M, Li M, Takahashi-Nakaguchi A, Chibana H, Lu J, Cai M, Kajiwara S, Kojima S.

Sci Rep. 2017 Jul 6;7(1):4746. doi: 10.1038/s41598-017-04630-8.


Convenient method for better preservation of fine structures of cultured macrophages and engulfed yeast cells by freeze-substitution fixation.

Yamaguchi M, Takahashi-Nakaguchi A, Aida Y, Sato-Okamoto M, Chibana H.

Microscopy (Oxf). 2017 Jun 1;66(3):209-211. doi: 10.1093/jmicro/dfx006.


Discrepancy between Hepatitis C Virus Genotypes and NS4-Based Serotypes: Association with Their Subgenomic Sequences.

Win NN, Nakamoto S, Kanda T, Takahashi H, Takahashi-Nakaguchi A, Yasui S, Nakamura M, Wu S, Imazeki F, Mikami S, Yokosuka O, Gonoi T, Shirasawa H.

Int J Mol Sci. 2017 Jan 17;18(1). pii: E172. doi: 10.3390/ijms18010172.


Putative orotate transporter of Cryptococcus neoformans, Oat1, is a member of the NCS1/PRT transporter super family and its loss causes attenuation of virulence.

Toh-E A, Ohkusu M, Shimizu K, Takahashi-Nakaguchi A, Kawamoto S, Ishiwada N, Watanabe A, Kamei K.

Curr Genet. 2017 Aug;63(4):697-707. doi: 10.1007/s00294-016-0672-5. Epub 2016 Dec 23.


The CgHaa1-Regulon Mediates Response and Tolerance to Acetic Acid Stress in the Human Pathogen Candida glabrata.

Bernardo RT, Cunha DV, Wang C, Pereira L, Silva S, Salazar SB, Schröder MS, Okamoto M, Takahashi-Nakaguchi A, Chibana H, Aoyama T, Sá-Correia I, Azeredo J, Butler G, Mira NP.

G3 (Bethesda). 2017 Jan 5;7(1):1-18. doi: 10.1534/g3.116.034660.


KRE5 Suppression Induces Cell Wall Stress and Alternative ER Stress Response Required for Maintaining Cell Wall Integrity in Candida glabrata.

Tanaka Y, Sasaki M, Ito F, Aoyama T, Sato-Okamoto M, Takahashi-Nakaguchi A, Chibana H, Shibata N.

PLoS One. 2016 Aug 22;11(8):e0161371. doi: 10.1371/journal.pone.0161371. eCollection 2016.


Draft Genome Sequence of the Pathogenic Filamentous Fungus Aspergillus udagawae Strain IFM 46973T.

Kusuya Y, Takahashi-Nakaguchi A, Takahashi H, Yaguchi T.

Genome Announc. 2015 Aug 6;3(4). pii: e00834-15. doi: 10.1128/genomeA.00834-15.


The Ubiquitin Ligase SCF(Ucc1) Acts as a Metabolic Switch for the Glyoxylate Cycle.

Nakatsukasa K, Nishimura T, Byrne SD, Okamoto M, Takahashi-Nakaguchi A, Chibana H, Okumura F, Kamura T.

Mol Cell. 2015 Jul 2;59(1):22-34. doi: 10.1016/j.molcel.2015.04.013. Epub 2015 May 14.


Identification of genes involved in the phosphate metabolism in Cryptococcus neoformans.

Toh-e A, Ohkusu M, Li HM, Shimizu K, Takahashi-Nakaguchi A, Gonoi T, Kawamoto S, Kanesaki Y, Yoshikawa H, Nishizawa M.

Fungal Genet Biol. 2015 Jul;80:19-30. doi: 10.1016/j.fgb.2015.04.019. Epub 2015 May 5.


Genome sequence comparison of Aspergillus fumigatus strains isolated from patients with pulmonary aspergilloma and chronic necrotizing pulmonary aspergillosis.

Takahashi-Nakaguchi A, Muraosa Y, Hagiwara D, Sakai K, Toyotome T, Watanabe A, Kawamoto S, Kamei K, Gonoi T, Takahashi H.

Med Mycol. 2015 May;53(4):353-60. doi: 10.1093/mmy/myv003.


Refeeding with glucose rather than fructose elicits greater hepatic inflammatory gene expression in mice.

Oarada M, Takahashi-Nakaguchi A, Abe T, Nikawa T, Miki T, Gonoi T.

Nutrition. 2015 May;31(5):757-65. doi: 10.1016/j.nut.2014.11.014. Epub 2014 Dec 19.


Whole-genome comparison of Aspergillus fumigatus strains serially isolated from patients with aspergillosis.

Hagiwara D, Takahashi H, Watanabe A, Takahashi-Nakaguchi A, Kawamoto S, Kamei K, Gonoi T.

J Clin Microbiol. 2014 Dec;52(12):4202-9. doi: 10.1128/JCM.01105-14. Epub 2014 Sep 17.


Pierisins and CARP-1: ADP-ribosylation of DNA by ARTCs in butterflies and shellfish.

Nakano T, Takahashi-Nakaguchi A, Yamamoto M, Watanabe M.

Curr Top Microbiol Immunol. 2015;384:127-49. doi: 10.1007/82_2014_416. Review.


Genome based analysis of type-I polyketide synthase and nonribosomal peptide synthetase gene clusters in seven strains of five representative Nocardia species.

Komaki H, Ichikawa N, Hosoyama A, Takahashi-Nakaguchi A, Matsuzawa T, Suzuki K, Fujita N, Gonoi T.

BMC Genomics. 2014 Apr 30;15:323. doi: 10.1186/1471-2164-15-323.


Effect of serum components on biofilm formation by Aspergillus fumigatus and other Aspergillus species.

Wuren T, Toyotome T, Yamaguchi M, Takahashi-Nakaguchi A, Muraosa Y, Yahiro M, Wang DN, Watanabe A, Taguchi H, Kamei K.

Jpn J Infect Dis. 2014;67(3):172-9.


Bromopyrrole alkaloids from a marine sponge Agelas sp.

Kusama T, Tanaka N, Takahashi-Nakaguchi A, Gonoi T, Fromont J, Kobayashi J.

Chem Pharm Bull (Tokyo). 2014;62(5):499-503.


Nakijiquinone S and nakijinol C, new meroterpenoids from a marine sponge of the family spongiidae.

Suzuki H, Kubota T, Takahashi-Nakaguchi A, Fromont J, Gonoi T, Kobayashi J.

Chem Pharm Bull (Tokyo). 2014;62(2):209-12.


Ultra-deep sequencing analysis of the hepatitis A virus 5'-untranslated region among cases of the same outbreak from a single source.

Wu S, Nakamoto S, Kanda T, Jiang X, Nakamura M, Miyamura T, Shirasawa H, Sugiura N, Takahashi-Nakaguchi A, Gonoi T, Yokosuka O.

Int J Med Sci. 2013 Dec 20;11(1):60-4. doi: 10.7150/ijms.7728. eCollection 2014.


NikA/TcsC histidine kinase is involved in conidiation, hyphal morphology, and responses to osmotic stress and antifungal chemicals in Aspergillus fumigatus.

Hagiwara D, Takahashi-Nakaguchi A, Toyotome T, Yoshimi A, Abe K, Kamei K, Gonoi T, Kawamoto S.

PLoS One. 2013 Dec 2;8(12):e80881. doi: 10.1371/journal.pone.0080881. eCollection 2013.


Prevalence of hepatitis C virus subgenotypes 1a and 1b in Japanese patients: ultra-deep sequencing analysis of HCV NS5B genotype-specific region.

Wu S, Kanda T, Nakamoto S, Jiang X, Miyamura T, Nakatani SM, Ono SK, Takahashi-Nakaguchi A, Gonoi T, Yokosuka O.

PLoS One. 2013 Sep 17;8(9):e73615. doi: 10.1371/journal.pone.0073615. eCollection 2013.


Male soldiers are functional in the Japanese strain of a polyembryonic wasp.

Uka D, Takahashi-Nakaguchi A, Yoshimura J, Iwabuchi K.

Sci Rep. 2013;3:2312. doi: 10.1038/srep02312.


Nagelamides X-Z, dimeric bromopyrrole alkaloids from a marine sponge Agelas sp.

Tanaka N, Kusama T, Takahashi-Nakaguchi A, Gonoi T, Fromont J, Kobayashi J.

Org Lett. 2013 Jul 5;15(13):3262-5. doi: 10.1021/ol401291n. Epub 2013 Jun 14.


Manzamenone O, new trimeric fatty acid derivative from a marine sponge Plakortis sp.

Tanaka N, Asai M, Takahashi-Nakaguchi A, Gonoi T, Fromont J, Kobayashi J.

Org Lett. 2013 May 17;15(10):2518-21. doi: 10.1021/ol4009975. Epub 2013 May 7.


Demonstration of cytotoxicity against wasps by pierisin-1: a possible defense factor in the cabbage white butterfly.

Takahashi-Nakaguchi A, Matsumoto Y, Yamamoto M, Iwabuchi K, Totsuka Y, Sugimura T, Wakabayashi K.

PLoS One. 2013 Apr 23;8(4):e60539. doi: 10.1371/journal.pone.0060539. Print 2013.


Zamamiphidin A, a new manzamine related alkaloid from an Okinawan marine sponge Amphimedon sp.

Kubota T, Kamijyo Y, Takahashi-Nakaguchi A, Fromont J, Gonoi T, Kobayashi J.

Org Lett. 2013 Feb 1;15(3):610-2. doi: 10.1021/ol3034274. Epub 2013 Jan 23.


ADP-ribosylation of guanosine by SCO5461 protein secreted from Streptomyces coelicolor.

Nakano T, Matsushima-Hibiya Y, Yamamoto M, Takahashi-Nakaguchi A, Fukuda H, Ono M, Takamura-Enya T, Kinashi H, Totsuka Y.

Toxicon. 2013 Mar 1;63:55-63. doi: 10.1016/j.toxicon.2012.11.019. Epub 2012 Dec 2.


Manzamenones L-N, new dimeric fatty-acid derivatives from an Okinawan marine sponge Plakortis sp.

Kubota T, Ishiguro Y, Takahashi-Nakaguchi A, Fromont J, Gonoi T, Kobayashi J.

Bioorg Med Chem Lett. 2013 Jan 1;23(1):244-7. doi: 10.1016/j.bmcl.2012.10.109. Epub 2012 Nov 2.


Entomological surveillance for flaviviruses at migratory bird stopover sites in Hokkaido, Japan, and a new insect flavivirus detected in Aedes galloisi (Diptera: Culicidae).

Hoshino K, Takahashi-Nakaguchi A, Isawa H, Sasaki T, Higa Y, Kasai S, Tsuda Y, Sawabe K, Kobayashi M.

J Med Entomol. 2012 Jan;49(1):175-82.


Nucleotide sequence and chromosomal localization of the gene for pierisin-1, a DNA ADP-ribosylating protein, in the cabbage butterfly Pieris rapae.

Yamamoto M, Takahashi-Nakaguchi A, Matsushima-Hibiya Y, Nakano T, Totsuka Y, Imanishi S, Mitsuhashi J, Watanabe M, Nakagama H, Sugimura T, Wakabayashi K.

Genetica. 2011 Oct;139(10):1251-8. doi: 10.1007/s10709-011-9626-5. Epub 2012 Jan 12.


The carbohydrate ligands on the host embryo mediate intercellular migration of the parasitic wasp embryo.

Takahashi-Nakaguchi A, Hiraoka T, Iwabuchi K.

FEBS Lett. 2011 Jul 21;585(14):2295-9. doi: 10.1016/j.febslet.2011.05.055. Epub 2011 Jun 12.


An ultrastructural study of polyembryonic parasitoid embryo and host embryo cell interactions.

Takahashi-Nakaguchi A, Hiraoka T, Iwabuchi K.

J Morphol. 2010 Jun;271(6):750-8. doi: 10.1002/jmor.10831.


Characterization of cell clusters in larval hemolymph of the cabbage armyworm Mamestra brassicae and their role in maintenance of hemocyte populations.

Mangalika PR, Kawamoto T, Takahashi-Nakaguchi A, Iwabuchi K.

J Insect Physiol. 2010 Mar;56(3):314-23. doi: 10.1016/j.jinsphys.2009.11.003. Epub 2009 Nov 21.


Molecular cloning of apoptosis-inducing Pierisin-like proteins, from two species of white butterfly, Pieris melete and Aporia crataegi.

Yamamoto M, Nakano T, Matsushima-Hibiya Y, Totsuka Y, Takahashi-Nakaguchi A, Matsumoto Y, Sugimura T, Wakabayashi K.

Comp Biochem Physiol B Biochem Mol Biol. 2009 Nov;154(3):326-33. doi: 10.1016/j.cbpb.2009.07.007. Epub 2009 Jul 23.


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