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The natural course of the paravertebral muscles after the onset of osteoporotic vertebral fracture.

Takahashi S, Hoshino M, Takayama K, Sasaoka R, Tsujio T, Yasuda H, Kanematsu F, Kono H, Toyoda H, Ohyama S, Hori Y, Nakamura H.

Osteoporos Int. 2020 Feb 14. doi: 10.1007/s00198-020-05338-8. [Epub ahead of print]


Antitumor Activity and Safety of Trastuzumab Deruxtecan in Patients With HER2-Low-Expressing Advanced Breast Cancer: Results From a Phase Ib Study.

Modi S, Park H, Murthy RK, Iwata H, Tamura K, Tsurutani J, Moreno-Aspitia A, Doi T, Sagara Y, Redfern C, Krop IE, Lee C, Fujisaki Y, Sugihara M, Zhang L, Shahidi J, Takahashi S.

J Clin Oncol. 2020 Feb 14:JCO1902318. doi: 10.1200/JCO.19.02318. [Epub ahead of print]


Preferential targeting cancer-related i-motif DNAs by the plant flavonol fisetin for theranostics applications.

Takahashi S, Bhattacharjee S, Ghosh S, Sugimoto N, Bhowmik S.

Sci Rep. 2020 Feb 13;10(1):2504. doi: 10.1038/s41598-020-59343-2.


A conserved strategy of chalcone isomerase-like protein to rectify promiscuous chalcone synthase specificity.

Waki T, Mameda R, Nakano T, Yamada S, Terashita M, Ito K, Tenma N, Li Y, Fujino N, Uno K, Yamashita S, Aoki Y, Denessiouk K, Kawai Y, Sugawara S, Saito K, Yonekura-Sakakibara K, Morita Y, Hoshino A, Takahashi S, Nakayama T.

Nat Commun. 2020 Feb 13;11(1):870. doi: 10.1038/s41467-020-14558-9.


Neurocognitive Function and Fetal Alcohol Spectrum Disorder in Offenders with Mental Disorders.

Mela M, Flannigan K, Anderson T, Nelson M, Krishnan S, Chizea C, Takahashi S, Sanjanwala R.

J Am Acad Psychiatry Law. 2020 Feb 12. pii: JAAPL.003886-20. doi: 10.29158/JAAPL.003886-20. [Epub ahead of print]


Microcirculation changes in gingival tissue after ultrasonic tooth preparation in beagle dogs.

To M, Matsuo M, Wada-Takahashi S, Sugiyama S, Tamaki K, Takahashi SS.

J Appl Oral Sci. 2020 Feb 7;28:e20190145. doi: 10.1590/1678-7757-2019-0145. eCollection 2020.


V-ATPase a3 isoform mutations identified in osteopetrosis patients abolish its expression and disrupt osteoclast function.

Matsumoto N, Matsukawa R, Takahashi S, Kudo K, Sun-Wada GH, Wada Y, Nakanishi-Matsui M.

Exp Cell Res. 2020 Feb 8:111901. doi: 10.1016/j.yexcr.2020.111901. [Epub ahead of print]


D-Aspartate oxidase: distribution, functions, properties, and biotechnological applications.

Takahashi S.

Appl Microbiol Biotechnol. 2020 Feb 11. doi: 10.1007/s00253-020-10439-9. [Epub ahead of print] Review.


Reconstitution of Circulating Mucosal-Associated Invariant T Cells after Allogeneic Hematopoietic Cell Transplantation: Its Association with the Riboflavin Synthetic Pathway of Gut Microbiota in Cord Blood Transplant Recipients.

Konuma T, Kohara C, Watanabe E, Takahashi S, Ozawa G, Suzuki K, Mizukami M, Nagai E, Jimbo K, Kaito Y, Isobe M, Kato S, Takahashi S, Chiba A, Miyake S, Tojo A.

J Immunol. 2020 Feb 10. pii: ji1900681. doi: 10.4049/jimmunol.1900681. [Epub ahead of print]


Metabolic compartmentalization between astroglia and neurons in physiological and pathophysiological conditions of the neurovascular unit.

Takahashi S.

Neuropathology. 2020 Feb 9. doi: 10.1111/neup.12639. [Epub ahead of print] Review.


Complete response to pembrolizumab in advanced hepatocellular carcinoma with microsatellite instability.

Ando Y, Yamauchi M, Suehiro Y, Yamaoka K, Kosaka Y, Fuji Y, Uchikawa S, Kodama K, Morio K, Fujino H, Nakahara T, Ono A, Murakami E, Kawaoka T, Takahashi S, Tsuge M, Hiramatsu A, Imamura M, Chayama K, Aikata H.

Clin J Gastroenterol. 2020 Feb 4. doi: 10.1007/s12328-020-01099-3. [Epub ahead of print]


Clinical significance of gene mutation in ctDNA analysis for hormone receptor-positive metastatic breast cancer.

Shibayama T, Low SK, Ono M, Kobayashi T, Kobayashi K, Fukada I, Ito Y, Ueno T, Ohno S, Nakamura Y, Takahashi S.

Breast Cancer Res Treat. 2020 Feb 4. doi: 10.1007/s10549-019-05512-5. [Epub ahead of print]


Decoupling from a Thermal Bath via Molecular Polariton Formation.

Takahashi S, Watanabe K.

J Phys Chem Lett. 2020 Feb 4:1349-1356. doi: 10.1021/acs.jpclett.9b03789. [Epub ahead of print]


Impact of Primary Pegfilgrastim Prophylaxis on Relative Dose Intensity in Neoadjuvant/Adjuvant FEC-100 Chemotherapy.

Yokokawa T, Suzuki K, Sugisaki T, Kobayashi K, Shouji D, Watanabe H, Kawakami K, Takiguchi T, Aoyama T, Kobayashi K, Takahashi S, Ito Y, Ohno S, Hama T.

Anticancer Res. 2020 Feb;40(2):915-921. doi: 10.21873/anticanres.14024.


Investigation of Approval Trends and Benefits of New Fixed-Dose Combination Drugs in Japan.

Kikuchi C, Ohno M, Izumo T, Takahashi S, Aoki M, Shimomura H, Kawano Y, Shimada S, Aoyama T.

Ther Innov Regul Sci. 2020 Jan;54(1):200-210. doi: 10.1007/s43441-019-00046-w.


Reduced dose of MTX for GVHD prophylaxis promotes engraftment and decreases non-relapse mortality in umbilical cord blood transplantation.

Shiratori S, Ohigashi H, Takahashi S, Ara T, Goto H, Nakagawa M, Sugita J, Onozawa M, Kahata K, Endo T, Hashimoto D, Teshima T; North Japan Hematology Study Group (NJHSG).

Ann Hematol. 2020 Feb 1. doi: 10.1007/s00277-020-03937-3. [Epub ahead of print]


Nonsystemic vasculitic neuropathy in a patient with IgG-monoclonal gammopathy of undetermined significance: A case report.

Kinno R, Osakabe Y, Takahashi S, Kurokawa S, Owan Y, Ono K, Baba Y.

Medicine (Baltimore). 2020 Jan;99(5):e19036. doi: 10.1097/MD.0000000000019036.


Luteolin suppresses bladder cancer growth via regulation of mechanistic target of rapamycin (mTOR) pathway.

Iida K, Naiki T, Naiki-Ito A, Suzuki S, Kato H, Nozaki S, Nagai T, Etani T, Nagayasu Y, Ando R, Kawai N, Yasui T, Takahashi S.

Cancer Sci. 2020 Jan 29. doi: 10.1111/cas.14334. [Epub ahead of print]


Efficacy of vibegron, a novel β3-adrenoreceptor agonist, on severe urgency urinary incontinence related to overactive bladder: Post-hoc analysis of a randomized, placebo-controlled, double-blind comparative phase 3 study.

Yoshida M, Takeda M, Gotoh M, Yokoyama O, Kakizaki H, Takahashi S, Masumori N, Nagai S, Minemura K.

BJU Int. 2020 Jan 28. doi: 10.1111/bju.15020. [Epub ahead of print]


Relationship between decreased cerebral blood flow and amnesia after microsurgery for anterior communicating artery aneurysm.

Mugikura S, Mori N, Kikuchi H, Mori E, Takahashi S, Takase K.

Ann Nucl Med. 2020 Jan 27. doi: 10.1007/s12149-020-01436-z. [Epub ahead of print]


Handmade leaf cutter for efficient and reliable ROS assay.

Desaki Y, Shimada H, Takahashi S, Sakurayama C, Kawai M, Kaku H, Shibuya N.

Plant Biotechnol (Tokyo). 2019 Dec 25;36(4):275-278. doi: 10.5511/plantbiotechnology.19.0921a.


Efficacy and Safety of Pembrolizumab in Previously Treated Advanced Neuroendocrine Tumors: Results From the Phase 2 KEYNOTE-158 Study.

Strosberg JR, Mizuno N, Doi T, Grande E, Delord JP, Shapira-Frommer R, Bergsland EK, Shah MH, Fakih M, Takahashi S, Piha-Paul SA, O'Neil BH, Thomas S, Lolkema M, Chen M, Ibrahim N, Norwood KG, Hadoux J.

Clin Cancer Res. 2020 Jan 24. pii: clincanres.3014.2019. doi: 10.1158/1078-0432.CCR-19-3014. [Epub ahead of print]


Intraocular infiltration of Philadelphia chromosome-positive acute lymphoblastic leukemia diagnosed by polymerase chain reaction from the aqueous humor: A case report.

Hiraoka M, Ohguro H, Ikeda H, Furuya D, Takahashi S.

Medicine (Baltimore). 2020 Jan;99(4):e18872. doi: 10.1097/MD.0000000000018872.


Mice lacking core 1-derived O-glycan in podocytes develop transient proteinuria, resulting in focal segmental glomerulosclerosis.

Fuseya S, Suzuki R, Okada R, Hagiwara K, Sato T, Narimatsu H, Yokoi H, Kasahara M, Usui T, Morito N, Yamagata K, Kudo T, Takahashi S.

Biochem Biophys Res Commun. 2020 Jan 20. pii: S0006-291X(20)30087-5. doi: 10.1016/j.bbrc.2020.01.033. [Epub ahead of print]


Accuracy of aortic dissection detection risk score alone or with D-dimer: A systematic review and meta-analysis.

Tsutsumi Y, Tsujimoto Y, Takahashi S, Tsuchiya A, Fukuma S, Yamamoto Y, Fukuhara S.

Eur Heart J Acute Cardiovasc Care. 2020 Jan 23:2048872620901831. doi: 10.1177/2048872620901831. [Epub ahead of print]


c-Maf deletion in adult C57BL/6J mice induces cataract formation and abnormal differentiation of lens fiber cells.

Fujino M, Tagami A, Ojima M, Mizuno S, Abdellatif AM, Kuno A, Takahashi S.

Exp Anim. 2020 Jan 21. doi: 10.1538/expanim.19-0137. [Epub ahead of print]


Precision Medicine in Soft Tissue Sarcoma Treatment.

Nakano K, Takahashi S.

Cancers (Basel). 2020 Jan 16;12(1). pii: E221. doi: 10.3390/cancers12010221. Review.


Outcomes and Prognostic Factors for Patients with Relapsed or Refractory Acute Lymphoblastic Leukemia Who Underwent Allogeneic Hematopoietic Cell Transplantation: A KSGCT Multicenter Analysis.

Tachibana T, Kanda J, Ishizaki T, Najima Y, Tanaka M, Doki N, Fujiwara SI, Kimura SI, Onizuka M, Takahashi S, Saito T, Mori T, Fujisawa S, Sakaida E, Matsumoto K, Aotsuka N, Gotoh M, Watanabe R, Shono K, Usuki K, Tsukada N, Kanamori H, Kanda Y, Okamoto S; Kanto Study Group for Cell Therapy (KSGCT).

Biol Blood Marrow Transplant. 2020 Jan 18. pii: S1083-8791(20)30018-5. doi: 10.1016/j.bbmt.2020.01.007. [Epub ahead of print]


Telomere length in CD4+ and CD8+ T cells among long-term survivors of adults after single cord blood transplantation.

Jimbo K, Konuma T, Mizukami M, Nagai E, Oiwa-Monna M, Isobe M, Kato S, Takahashi S, Tojo A.

Eur J Haematol. 2020 Jan 20. doi: 10.1111/ejh.13385. [Epub ahead of print]


Liquid-like droplet formation by tumor suppressor p53 induced by multivalent electrostatic interactions between two disordered domains.

Kamagata K, Kanbayashi S, Honda M, Itoh Y, Takahashi H, Kameda T, Nagatsugi F, Takahashi S.

Sci Rep. 2020 Jan 17;10(1):580. doi: 10.1038/s41598-020-57521-w.


Outcomes of regional-based newborn hearing screening for 35,461 newborns for 5 years in Akita, Japan.

Sato T, Nakazawa M, Takahashi S, Mizuno T, Ishikawa K, Yamada T.

Int J Pediatr Otorhinolaryngol. 2020 Jan 10;131:109870. doi: 10.1016/j.ijporl.2020.109870. [Epub ahead of print]


Transcription factor c-Maf is a checkpoint that programs macrophages in lung cancer.

Liu M, Tong Z, Ding C, Luo F, Wu S, Wu C, Albeituni S, He L, Hu X, Tieri D, Rouchka EC, Hamada M, Takahashi S, Gibb AA, Kloecker G, Zhang HG, Bousamra M, Hill BG, Zhang X, Yan J.

J Clin Invest. 2020 Jan 16. pii: 131335. doi: 10.1172/JCI131335. [Epub ahead of print]


Cytosolic domain of SIDT2 carries an arginine-rich motif that binds to RNA/DNA and is important for the direct transport of nucleic acids into lysosomes.

Hase K, Contu VR, Kabuta C, Sakai R, Takahashi M, Kataoka N, Hakuno F, Takahashi SI, Fujiwara Y, Wada K, Kabuta T.

Autophagy. 2020 Jan 16:1-15. doi: 10.1080/15548627.2020.1712109. [Epub ahead of print]


Atypical Rett syndrome in a girl with mosaic triple X and MECP2 variant.

Takahashi S, Takeguchi R, Kuroda M, Tanaka R.

Mol Genet Genomic Med. 2020 Jan 13:e1122. doi: 10.1002/mgg3.1122. [Epub ahead of print]


Longitudinal and cross-sectional detection of four bovine enteric viruses by multiplex- reverse transcription polymerase chain reaction: identification of possible indicator viruses to assess biosecurity level at bovine farms.

Yamada M, Kubota K, Takahashi S, Toyofuku C, Hakim H, Alam MS, Hasan MA, Shoham D, Takehara K.

J Vet Med Sci. 2020 Jan 16. doi: 10.1292/jvms.19-0235. [Epub ahead of print]


A case of myelodysplastic syndrome with t(10;18)(q26;q21).

Ohba Y, Yamada-Fujiwara M, Minagawa T, Watanabe S, Okitsu Y, Izumi Y, Kameoka J, Takahashi S.

J Lab Physicians. 2019 Oct-Dec;11(4):382-384. doi: 10.4103/JLP.JLP_61_19.


Ropinirole, a New ALS Drug Candidate Developed Using iPSCs.

Okano H, Yasuda D, Fujimori K, Morimoto S, Takahashi S.

Trends Pharmacol Sci. 2020 Feb;41(2):99-109. doi: 10.1016/ Epub 2020 Jan 8. Review.


Editorial: Neuromodulation in Basic, Translational and Clinical Research in Psychiatry.

Ishii R, Nishida K, Youssef NA, Jann K, Takahashi S.

Front Hum Neurosci. 2019 Dec 20;13:438. doi: 10.3389/fnhum.2019.00438. eCollection 2019. No abstract available.


The Reconfigurable Maze Provides Flexible, Scalable, Reproducible, and Repeatable Tests.

Hoshino S, Takahashi R, Mieno K, Tamatsu Y, Azechi H, Ide K, Takahashi S.

iScience. 2020 Jan 24;23(1):100787. doi: 10.1016/j.isci.2019.100787. Epub 2019 Dec 19.


Detecting cognitive decline in community-dwelling older adults using simple cognitive and motor performance tests.

Tomita Y, Tanaka S, Takahashi S, Takeuchi N.

Geriatr Gerontol Int. 2020 Jan 9. doi: 10.1111/ggi.13863. [Epub ahead of print]


Rational Design of a Near-infrared Fluorescence Probe for Ca2+ Based on Phosphorus-substituted Rhodamines Utilizing Photoinduced Electron Transfer.

Takahashi S, Hanaoka K, Okubo Y, Echizen H, Ikeno T, Komatsu T, Ueno T, Hirose K, Iino M, Nagano T, Urano Y.

Chem Asian J. 2020 Jan 7. doi: 10.1002/asia.201901689. [Epub ahead of print]


Deficiency of core fucosylation activates cellular signaling dependent on FLT3 expression in a Ba/F3 cell system.

Duan C, Fukuda T, Isaji T, Qi F, Yang J, Wang Y, Takahashi S, Gu J.

FASEB J. 2020 Feb;34(2):3239-3252. doi: 10.1096/fj.201902313RR. Epub 2020 Jan 5.


Silent MRA: arterial spin labeling magnetic resonant angiography with ultra-short time echo assessing cerebral arteriovenous malformation.

Arai N, Akiyama T, Fujiwara K, Koike K, Takahashi S, Horiguchi T, Jinzaki M, Yoshida K.

Neuroradiology. 2020 Jan 3. doi: 10.1007/s00234-019-02345-3. [Epub ahead of print]


Emergency thromboembolectomy for impending paradoxical embolism through a patent foramen ovale owing to venous thromboembolism in a severely obese patient.

Matsumoto R, Fukuda S, Kano M, Suzuki S, Maruno K, Iwahori A, Takahashi S, Kamiya K, Nishibe T, Ogino H.

Gen Thorac Cardiovasc Surg. 2020 Jan 2. doi: 10.1007/s11748-019-01283-4. [Epub ahead of print]


Reference Value of Brain Tissue Oxygen Saturation in Newborns Immediately After Birth.

Kato R, Hosono S, Takahashi S.

Adv Exp Med Biol. 2020;1232:19-24. doi: 10.1007/978-3-030-34461-0_3.


Essential Role of Host Double-Stranded DNA Released from Dying Cells by Cationic Liposomes for Mucosal Adjuvanticity.

Tada R, Ohshima A, Tanazawa Y, Ohmi A, Takahashi S, Kiyono H, Kunisawa J, Aramaki Y, Negishi Y.

Vaccines (Basel). 2019 Dec 27;8(1). pii: E8. doi: 10.3390/vaccines8010008.


Improvement of physical and oral function in community-dwelling older people after a 3-month long-term care prevention program including physical exercise, oral health instruction, and nutritional guidance.

Iwao Y, Shigeishi H, Takahashi S, Uchida S, Kawano S, Sugiyama M.

Clin Exp Dent Res. 2019 Aug 6;5(6):611-619. doi: 10.1002/cre2.226. eCollection 2019 Dec.


Distribution of Flavan-3-ol Species in Ripe Strawberry Fruit Revealed by Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Imaging.

Enomoto H, Takahashi S, Takeda S, Hatta H.

Molecules. 2019 Dec 26;25(1). pii: E103. doi: 10.3390/molecules25010103.


Soil and sediment contamination by unsubstituted and methylated polycyclic aromatic hydrocarbons in an informal e-waste recycling area, northern Vietnam: Occurrence, source apportionment, and risk assessment.

Hoa NTQ, Anh HQ, Tue NM, Trung NT, Da LN, Van Quy T, Huong NTA, Suzuki G, Takahashi S, Tanabe S, Thuy PC, Dau PT, Viet PH, Tuyen LH.

Sci Total Environ. 2020 Mar 20;709:135852. doi: 10.1016/j.scitotenv.2019.135852. Epub 2019 Dec 5.


Impact of spaceflight on the murine thymus and mitigation by exposure to artificial gravity during spaceflight.

Horie K, Kato T, Kudo T, Sasanuma H, Miyauchi M, Akiyama N, Miyao T, Seki T, Ishikawa T, Takakura Y, Shirakawa M, Shiba D, Hamada M, Jeon H, Yoshida N, Inoue JI, Muratani M, Takahashi S, Ohno H, Akiyama T.

Sci Rep. 2019 Dec 27;9(1):19866. doi: 10.1038/s41598-019-56432-9.

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