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Anti-Inflammatory Effects of EM900 on Cultured Human Nasal Epithelial Cells.
Wakayama N, Matsune S, Takahara E, Sekine K, Yoshioka Y, Ishida M, Yamaguchi S, Okubo K, Sunazuka T, Ōmura S.
J Nippon Med Sch. 2018;85(5):265-270. doi: 10.1272/jnms.JNMS.2018_85-42.
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Synthesis and gastrointestinal prokinetic activity of novel benzamide derivatives with amphoteric side chains.
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Accumulation of the 1-methyl-4-phenylpyridinium ion in suncus (Suncus murinus) brain: implication for flavin-containing monooxygenase activity in brain microvessels.
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The involvement of flavin-containing monooxygenase but not CYP3A4 in metabolism of itopride hydrochloride, a gastroprokinetic agent: comparison with cisapride and mosapride citrate.
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A high-level expression of CYP2A in the lung of the suncus (Suncus murinus) and its role in the activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
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The suncus (Suncus murinus) shows poor metabolic phenotype for trimethylamine N-oxygenation.
Mushiroda T, Yokoi T, Takahara E, Nagata O, Kato H, Kamataki T.
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Sensitive assay of trimethylamine N-oxide in liver microsomes by headspace gas chromatography with flame thermionic detection.
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Decalcification of calcium polycarbophil in rats.
Yamada T, Saito T, Takahara E, Nagata O, Tamai I, Tsuji A.
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Sensitive analytical method for the novel H1-receptor antagonist HSR-609 in human plasma and urine by high-performance liquid chromatography with pre-column fluorescent derivatization.
Hasegawa H, Takahara E, Yamada T, Nagata O.
J Chromatogr B Biomed Appl. 1996 Dec 13;687(2):419-25.
Amphoteric drugs. I. Synthesis and antiallergic activity of [4-(diphenylmethoxy)piperidino]-, [4-(diphenylmethyl)piperazinyl]- and [4-(diphenylmethylene)piperidino]alkanoic acid derivatives.
Iwasaki N, Sakaguchi J, Ohashi T, Takahara E, Ogawa N, Yasuda S, Koshinaka E, Kato H, Ito Y, Sawanishi H.
Chem Pharm Bull (Tokyo). 1994 Nov;42(11):2276-84.
Inter-individual differences of 4-[4-(4-methylphenyl)-phenylmethoxy-1-piperidinyl]butyric acid disposition in rats: possible involvement of genetic polymorphism.
Takahara E, Nagata O, Kato H, Ohta S, Hirobe M.
Drug Metab Dispos. 1994 Sep-Oct;22(5):761-9.
Analysis of urinary and biliary metabolites of (+)-4-[4-(4-methylphenyl)phenylmethoxy-1-piperidinyl]butyric acid in rats by liquid chromatography-frit-fast atom bombardment mass spectrometry.
J Chromatogr B Biomed Appl. 1994 Aug 5;658(1):154-60.
Inter-individual differences of (+)-4-[4-(4-methylphenyl)phenylmethoxy-1-piperidinyl]butyric acid ((+)-MPPB) disposition in rats.
Biol Pharm Bull. 1993 Oct;16(10):1057-9.
Effects of oxygen concentration on the metabolism of anisole homologues by rat liver microsomes.
Ohi H, Takahara E, Ohta S, Hirobe M.
Xenobiotica. 1992 Nov;22(11):1329-37.
Simultaneous determination of a new gastrointestinal prokinetic agent (HSR-803) and its metabolites in human serum and urine by high-performance liquid chromatography using automated column-switching.
Takahara E, Fukuoka H, Takagi T, Nagata O, Kato H.
J Chromatogr. 1992 Apr 15;576(1):174-8.
Determination of a new muscle relaxant (HY-770) in human serum by gas chromatography-mass spectrometry.
Nagata O, Sakashita T, Takahara E, Kato H, Kiriyama N.
J Chromatogr. 1989 Nov 24;496(2):456-62. No abstract available.
Effect of oxygen concentration on the metabolic pathway of anisole in rat liver microsomes.
Takahara E, Ohta S, Hirobe M.
Biochem Pharmacol. 1986 Feb 1;35(3):541-4. No abstract available.
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