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Items: 1 to 50 of 289

1.

Impaired ligand-dependent MET activation caused by an extracellular SEMA domain missense mutation in lung cancer.

Miao W, Sakai K, Sato H, Imamura R, Jangphattananont N, Takagi J, Nishita M, Minami Y, Matsumoto K.

Cancer Sci. 2019 Jul 24. doi: 10.1111/cas.14142. [Epub ahead of print]

2.

Distinct Localization of Mature HGF from its Precursor Form in Developing and Repairing the Stomach.

Jangphattananont N, Sato H, Imamura R, Sakai K, Terakado Y, Murakami K, Barker N, Oshima H, Oshima M, Takagi J, Kato Y, Yano S, Matsumoto K.

Int J Mol Sci. 2019 Jun 17;20(12). pii: E2955. doi: 10.3390/ijms20122955.

3.

Candida albicans white and opaque cells exhibit distinct spectra of organ colonization in mouse models of infection.

Takagi J, Singh-Babak SD, Lohse MB, Dalal CK, Johnson AD.

PLoS One. 2019 Jun 6;14(6):e0218037. doi: 10.1371/journal.pone.0218037. eCollection 2019.

4.

Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor.

Sakai K, Passioura T, Sato H, Ito K, Furuhashi H, Umitsu M, Takagi J, Kato Y, Mukai H, Warashina S, Zouda M, Watanabe Y, Yano S, Shibata M, Suga H, Matsumoto K.

Nat Chem Biol. 2019 Jun;15(6):598-606. doi: 10.1038/s41589-019-0285-7. Epub 2019 May 17.

PMID:
31101918
5.

Structural basis for oligomerization of the prokaryotic peptide transporter PepTSo2.

Nagamura R, Fukuda M, Kawamoto A, Matoba K, Dohmae N, Ishitani R, Takagi J, Nureki O.

Acta Crystallogr F Struct Biol Commun. 2019 May 1;75(Pt 5):348-358. doi: 10.1107/S2053230X19003546. Epub 2019 Apr 24.

6.

Crystal structure of a mammalian Wnt-frizzled complex.

Hirai H, Matoba K, Mihara E, Arimori T, Takagi J.

Nat Struct Mol Biol. 2019 May;26(5):372-379. doi: 10.1038/s41594-019-0216-z. Epub 2019 Apr 29.

PMID:
31036956
7.

Structural Basis of Sarco/Endoplasmic Reticulum Ca2+-ATPase 2b Regulation via Transmembrane Helix Interplay.

Inoue M, Sakuta N, Watanabe S, Zhang Y, Yoshikaie K, Tanaka Y, Ushioda R, Kato Y, Takagi J, Tsukazaki T, Nagata K, Inaba K.

Cell Rep. 2019 Apr 23;27(4):1221-1230.e3. doi: 10.1016/j.celrep.2019.03.106.

8.

Mechanically Distinct Microtubule Arrays Determine the Length and Force Response of the Meiotic Spindle.

Takagi J, Sakamoto R, Shiratsuchi G, Maeda YT, Shimamoto Y.

Dev Cell. 2019 Apr 22;49(2):267-278.e5. doi: 10.1016/j.devcel.2019.03.014. Epub 2019 Apr 11.

PMID:
30982663
9.

Advances in domain and subunit localization technology for electron microscopy.

Brown ZP, Takagi J.

Biophys Rev. 2019 Apr;11(2):149-155. doi: 10.1007/s12551-019-00513-6. Epub 2019 Mar 5. Review.

10.

The PA Tag: A Versatile Peptide Tagging System in the Era of Integrative Structural Biology.

Brown ZP, Takagi J.

Adv Exp Med Biol. 2018;1105:59-76. doi: 10.1007/978-981-13-2200-6_6. Review.

PMID:
30617824
11.

A Golgi-Released Subpopulation of the Trans-Golgi Network Mediates Protein Secretion in Arabidopsis.

Uemura T, Nakano RT, Takagi J, Wang Y, Kramer K, Finkemeier I, Nakagami H, Tsuda K, Ueda T, Schulze-Lefert P, Nakano A.

Plant Physiol. 2019 Feb;179(2):519-532. doi: 10.1104/pp.18.01228. Epub 2018 Dec 13.

12.

Cellular signaling and gene expression profiles evoked by a bivalent macrocyclic peptide that serves as an artificial MET receptor agonist.

Miao W, Sakai K, Ozawa N, Nishiuchi T, Suzuki Y, Ito K, Morioka T, Umitsu M, Takagi J, Suga H, Matsumoto K.

Sci Rep. 2018 Nov 7;8(1):16492. doi: 10.1038/s41598-018-34835-4.

13.

Efficient CRISPR/Cas9-based genome editing and its application to conditional genetic analysis in Marchantia polymorpha.

Sugano SS, Nishihama R, Shirakawa M, Takagi J, Matsuda Y, Ishida S, Shimada T, Hara-Nishimura I, Osakabe K, Kohchi T.

PLoS One. 2018 Oct 31;13(10):e0205117. doi: 10.1371/journal.pone.0205117. eCollection 2018.

14.

Off-axis rotor in Enterococcus hirae V-ATPase visualized by Zernike phase plate single-particle cryo-electron microscopy.

Tsunoda J, Song C, Imai FL, Takagi J, Ueno H, Murata T, Iino R, Murata K.

Sci Rep. 2018 Oct 23;8(1):15632. doi: 10.1038/s41598-018-33977-9.

15.

Structure and mechanism of cancer-associated N-acetylglucosaminyltransferase-V.

Nagae M, Kizuka Y, Mihara E, Kitago Y, Hanashima S, Ito Y, Takagi J, Taniguchi N, Yamaguchi Y.

Nat Commun. 2018 Aug 23;9(1):3380. doi: 10.1038/s41467-018-05931-w.

16.

Simultaneous observation of intermittent locomotion of multiple fish by fine-scale spatiotemporal three-dimensional positioning.

Takagi J, Ichikawa K, Arai N, Miyamoto Y, Uchida K, Shoji J, Mitamura H.

PLoS One. 2018 Jul 19;13(7):e0201029. doi: 10.1371/journal.pone.0201029. eCollection 2018.

17.

Use of Brefeldin A and Wortmannin to Dissect Post-Golgi Organelles Related to Vacuolar Transport in Arabidopsis thaliana.

Takagi J, Uemura T.

Methods Mol Biol. 2018;1789:155-165. doi: 10.1007/978-1-4939-7856-4_12.

PMID:
29916078
18.

A mutation in transcription factor MAFB causes Focal Segmental Glomerulosclerosis with Duane Retraction Syndrome.

Sato Y, Tsukaguchi H, Morita H, Higasa K, Tran MTN, Hamada M, Usui T, Morito N, Horita S, Hayashi T, Takagi J, Yamaguchi I, Nguyen HT, Harada M, Inui K, Maruta Y, Inoue Y, Koiwa F, Sato H, Matsuda F, Ayabe S, Mizuno S, Sugiyama F, Takahashi S, Yoshimura A.

Kidney Int. 2018 Aug;94(2):396-407. doi: 10.1016/j.kint.2018.02.025. Epub 2018 May 18.

PMID:
29779709
19.

Semaphorin 6D reverse signaling controls macrophage lipid metabolism and anti-inflammatory polarization.

Kang S, Nakanishi Y, Kioi Y, Okuzaki D, Kimura T, Takamatsu H, Koyama S, Nojima S, Nishide M, Hayama Y, Kinehara Y, Kato Y, Nakatani T, Shimogori T, Takagi J, Toyofuku T, Kumanogoh A.

Nat Immunol. 2018 Jun;19(6):561-570. doi: 10.1038/s41590-018-0108-0. Epub 2018 May 18.

PMID:
29777213
20.

Facile Synthesis of Dimeric Thioether-Macrocyclic Peptides with Antibody-like Affinity against Plexin-B1.

Bashiruddin NK, Matsunaga Y, Nagano M, Takagi J, Suga H.

Bioconjug Chem. 2018 Jun 20;29(6):1847-1851. doi: 10.1021/acs.bioconjchem.8b00219. Epub 2018 May 21.

PMID:
29714478
21.

A systematic survey of conformational states in β1 and β4 integrins using negative-stain electron microscopy.

Miyazaki N, Iwasaki K, Takagi J.

J Cell Sci. 2018 May 22;131(10). pii: jcs216754. doi: 10.1242/jcs.216754.

22.

Yeast Inner-Subunit PA-NZ-1 Labeling Strategy for Accurate Subunit Identification in a Macromolecular Complex through Cryo-EM Analysis.

Wang H, Han W, Takagi J, Cong Y.

J Mol Biol. 2018 May 11;430(10):1417-1425. doi: 10.1016/j.jmb.2018.03.026. Epub 2018 Apr 4.

PMID:
29625202
23.

Spontaneous adrenocorticotropic hormone (ACTH) normalisation due to tumour regression induced by metyrapone in a patient with ectopic ACTH syndrome: case report and literature review.

Iwayama H, Hirase S, Nomura Y, Ito T, Morita H, Otake K, Okumura A, Takagi J.

BMC Endocr Disord. 2018 Mar 27;18(1):19. doi: 10.1186/s12902-018-0246-2.

24.

Plant Vacuoles.

Shimada T, Takagi J, Ichino T, Shirakawa M, Hara-Nishimura I.

Annu Rev Plant Biol. 2018 Apr 29;69:123-145. doi: 10.1146/annurev-arplant-042817-040508. Epub 2018 Mar 21. Review.

PMID:
29561663
25.

An anti-peptide monoclonal antibody recognizing the tobacco etch virus protease-cleavage sequence and its application to a tandem tagging system.

Tabata S, Kitago Y, Fujii Y, Mihara E, Tamura-Kawakami K, Norioka N, Takahashi K, Kaneko MK, Kato Y, Takagi J.

Protein Expr Purif. 2018 Jul;147:94-99. doi: 10.1016/j.pep.2018.03.004. Epub 2018 Mar 14.

PMID:
29550370
26.
27.

Corrigendum: Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors.

Saito F, Hirayasu K, Satoh T, Wang CW, Lusingu J, Arimori T, Shida K, Palacpac NMQ, Itagaki S, Iwanaga S, Takashima E, Tsuboi T, Kohyama M, Suenaga T, Colonna M, Takagi J, Lavstsen T, Horii T, Arase H.

Nature. 2018 Feb 22;554(7693):554. doi: 10.1038/nature25498. Epub 2018 Feb 14.

PMID:
29443969
28.

Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression.

Seino T, Kawasaki S, Shimokawa M, Tamagawa H, Toshimitsu K, Fujii M, Ohta Y, Matano M, Nanki K, Kawasaki K, Takahashi S, Sugimoto S, Iwasaki E, Takagi J, Itoi T, Kitago M, Kitagawa Y, Kanai T, Sato T.

Cell Stem Cell. 2018 Mar 1;22(3):454-467.e6. doi: 10.1016/j.stem.2017.12.009. Epub 2018 Jan 11.

29.

Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors.

Saito F, Hirayasu K, Satoh T, Wang CW, Lusingu J, Arimori T, Shida K, Palacpac NMQ, Itagaki S, Iwanaga S, Takashima E, Tsuboi T, Kohyama M, Suenaga T, Colonna M, Takagi J, Lavstsen T, Horii T, Arase H.

Nature. 2017 Dec 7;552(7683):101-105. doi: 10.1038/nature24994. Epub 2017 Nov 29. Erratum in: Nature. 2018 Feb 14;:.

30.

Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus.

Sakakibara S, Arimori T, Yamashita K, Jinzai H, Motooka D, Nakamura S, Li S, Takeda K, Katayama J, El Hussien MA, Narazaki M, Tanaka T, Standley DM, Takagi J, Kikutani H.

Sci Rep. 2017 Nov 27;7(1):16428. doi: 10.1038/s41598-017-16681-y.

31.

Development of a new protein labeling system to map subunits and domains of macromolecular complexes for electron microscopy.

Brown ZP, Arimori T, Iwasaki K, Takagi J.

J Struct Biol. 2018 Mar;201(3):247-251. doi: 10.1016/j.jsb.2017.11.006. Epub 2017 Nov 21.

PMID:
29170031
32.

The activated conformation of integrin β7 is a novel multiple myeloma-specific target for CAR T cell therapy.

Hosen N, Matsunaga Y, Hasegawa K, Matsuno H, Nakamura Y, Makita M, Watanabe K, Yoshida M, Satoh K, Morimoto S, Fujiki F, Nakajima H, Nakata J, Nishida S, Tsuboi A, Oka Y, Manabe M, Ichihara H, Aoyama Y, Mugitani A, Nakao T, Hino M, Uchibori R, Ozawa K, Baba Y, Terakura S, Wada N, Morii E, Nishimura J, Takeda K, Oji Y, Sugiyama H, Takagi J, Kumanogoh A.

Nat Med. 2017 Dec;23(12):1436-1443. doi: 10.1038/nm.4431. Epub 2017 Nov 6.

PMID:
29106400
33.

Molecular dissection of protein-protein interactions between integrin α5β1 and the Helicobacter pylori Cag type IV secretion system.

Koelblen T, Bergé C, Cherrier MV, Brillet K, Jimenez-Soto L, Ballut L, Takagi J, Montserret R, Rousselle P, Fischer W, Haas R, Fronzes R, Terradot L.

FEBS J. 2017 Dec;284(23):4143-4157. doi: 10.1111/febs.14299. Epub 2017 Nov 12.

34.

Fv-clasp: An Artificially Designed Small Antibody Fragment with Improved Production Compatibility, Stability, and Crystallizability.

Arimori T, Kitago Y, Umitsu M, Fujii Y, Asaki R, Tamura-Kawakami K, Takagi J.

Structure. 2017 Oct 3;25(10):1611-1622.e4. doi: 10.1016/j.str.2017.08.011. Epub 2017 Sep 14.

35.

Mechanistic basis for the recognition of laminin-511 by α6β1 integrin.

Takizawa M, Arimori T, Taniguchi Y, Kitago Y, Yamashita E, Takagi J, Sekiguchi K.

Sci Adv. 2017 Sep 1;3(9):e1701497. doi: 10.1126/sciadv.1701497. eCollection 2017 Sep.

36.

High-quality frozen extracts of Xenopus laevis eggs reveal size-dependent control of metaphase spindle micromechanics.

Takagi J, Shimamoto Y.

Mol Biol Cell. 2017 Aug 1;28(16):2170-2177. doi: 10.1091/mbc.E17-03-0174. Epub 2017 Jun 7.

37.

Loss of Parkinson's disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c.

Meng H, Yamashita C, Shiba-Fukushima K, Inoshita T, Funayama M, Sato S, Hatta T, Natsume T, Umitsu M, Takagi J, Imai Y, Hattori N.

Nat Commun. 2017 Jun 7;8:15500. doi: 10.1038/ncomms15500.

38.

Structural basis for perception of diverse chemical substances by T1r taste receptors.

Nuemket N, Yasui N, Kusakabe Y, Nomura Y, Atsumi N, Akiyama S, Nango E, Kato Y, Kaneko MK, Takagi J, Hosotani M, Yamashita A.

Nat Commun. 2017 May 23;8:15530. doi: 10.1038/ncomms15530.

39.

Structural basis for ligand capture and release by the endocytic receptor ApoER2.

Hirai H, Yasui N, Yamashita K, Tabata S, Yamamoto M, Takagi J, Nogi T.

EMBO Rep. 2017 Jun;18(6):982-999. doi: 10.15252/embr.201643521. Epub 2017 Apr 26.

40.

Mechanistic insights into ectodomain shedding: susceptibility of CADM1 adhesion molecule is determined by alternative splicing and O-glycosylation.

Shirakabe K, Omura T, Shibagaki Y, Mihara E, Homma K, Kato Y, Yoshimura A, Murakami Y, Takagi J, Hattori S, Ogawa Y.

Sci Rep. 2017 Apr 10;7:46174. doi: 10.1038/srep46174.

41.

2D hybrid analysis: Approach for building three-dimensional atomic model by electron microscopy image matching.

Matsumoto A, Miyazaki N, Takagi J, Iwasaki K.

Sci Rep. 2017 Mar 23;7(1):377. doi: 10.1038/s41598-017-00337-y.

42.

The unique prodomain of T-cadherin plays a key role in adiponectin binding with the essential extracellular cadherin repeats 1 and 2.

Fukuda S, Kita S, Obata Y, Fujishima Y, Nagao H, Masuda S, Tanaka Y, Nishizawa H, Funahashi T, Takagi J, Maeda N, Shimomura I.

J Biol Chem. 2017 May 12;292(19):7840-7849. doi: 10.1074/jbc.M117.780734. Epub 2017 Mar 21.

43.

Endoplasmic-reticulum-mediated microtubule alignment governs cytoplasmic streaming.

Kimura K, Mamane A, Sasaki T, Sato K, Takagi J, Niwayama R, Hufnagel L, Shimamoto Y, Joanny JF, Uchida S, Kimura A.

Nat Cell Biol. 2017 Apr;19(4):399-406. doi: 10.1038/ncb3490. Epub 2017 Mar 13.

PMID:
28288129
44.

Spatial confinement of active microtubule networks induces large-scale rotational cytoplasmic flow.

Suzuki K, Miyazaki M, Takagi J, Itabashi T, Ishiwata S.

Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):2922-2927. doi: 10.1073/pnas.1616001114. Epub 2017 Mar 6.

45.

Conformational Freedom of the LRP6 Ectodomain Is Regulated by N-glycosylation and the Binding of the Wnt Antagonist Dkk1.

Matoba K, Mihara E, Tamura-Kawakami K, Miyazaki N, Maeda S, Hirai H, Thompson S, Iwasaki K, Takagi J.

Cell Rep. 2017 Jan 3;18(1):32-40. doi: 10.1016/j.celrep.2016.12.017.

46.

Allosteric Inhibition of a Semaphorin 4D Receptor Plexin B1 by a High-Affinity Macrocyclic Peptide.

Matsunaga Y, Bashiruddin NK, Kitago Y, Takagi J, Suga H.

Cell Chem Biol. 2016 Nov 17;23(11):1341-1350. doi: 10.1016/j.chembiol.2016.09.015. Epub 2016 Oct 27.

47.
48.

Redox-assisted regulation of Ca2+ homeostasis in the endoplasmic reticulum by disulfide reductase ERdj5.

Ushioda R, Miyamoto A, Inoue M, Watanabe S, Okumura M, Maegawa KI, Uegaki K, Fujii S, Fukuda Y, Umitsu M, Takagi J, Inaba K, Mikoshiba K, Nagata K.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6055-E6063. Epub 2016 Sep 30.

49.

Global Identification of Biofilm-Specific Proteolysis in Candida albicans.

Winter MB, Salcedo EC, Lohse MB, Hartooni N, Gulati M, Sanchez H, Takagi J, Hube B, Andes DR, Johnson AD, Craik CS, Nobile CJ.

MBio. 2016 Sep 13;7(5). pii: e01514-16. doi: 10.1128/mBio.01514-16.

50.

Probing conformational and functional states of human hepatocyte growth factor by a panel of monoclonal antibodies.

Umitsu M, Sakai K, Ogasawara S, Kaneko MK, Asaki R, Tamura-Kawakami K, Kato Y, Matsumoto K, Takagi J.

Sci Rep. 2016 Sep 9;6:33149. doi: 10.1038/srep33149.

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