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Items: 1 to 50 of 121

1.

Farnesoid X Receptor Activation Enhances Transforming Growth Factor β-Induced Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma Cells.

Kainuma M, Takada I, Makishima M, Sano K.

Int J Mol Sci. 2018 Jun 28;19(7). pii: E1898. doi: 10.3390/ijms19071898.

2.

Ess2 bridges transcriptional regulators and spliceosomal complexes via distinct interacting domains.

Takada I, Tsuchiya M, Yanaka K, Hidano S, Takahashi S, Kobayashi T, Ogawa H, Nakagawa S, Makishima M.

Biochem Biophys Res Commun. 2018 Mar 4;497(2):597-604. doi: 10.1016/j.bbrc.2018.02.110. Epub 2018 Feb 16.

PMID:
29454968
3.

Control of Inflammatory Bowel Disease and Colorectal Cancer by Synthetic Vitamin D Receptor Ligands.

Takada I, Makishima M.

Curr Med Chem. 2017;24(9):868-875. doi: 10.2174/0929867323666161202145509. Review.

PMID:
27915991
4.

Therapeutic application of vitamin D receptor ligands: an updated patent review.

Takada I, Makishima M.

Expert Opin Ther Pat. 2015;25(12):1373-83. doi: 10.1517/13543776.2015.1093113. Epub 2015 Sep 24. Review.

PMID:
26402335
5.

The ribosomal S6 kinase inhibitor BI-D1870 ameliorated experimental autoimmune encephalomyelitis in mice.

Takada I, Yogiashi Y, Makishima M.

Immunobiology. 2016 Feb;221(2):188-92. doi: 10.1016/j.imbio.2015.09.008. Epub 2015 Sep 8.

PMID:
26386981
6.

PPARγ ligands and their therapeutic applications: a patent review (2008 - 2014).

Takada I, Makishima M.

Expert Opin Ther Pat. 2015 Feb;25(2):175-91. doi: 10.1517/13543776.2014.985206. Epub 2014 Nov 21. Review.

PMID:
25416646
7.

DGCR14 induces Il17a gene expression through the RORγ/BAZ1B/RSKS2 complex.

Takada I.

Mol Cell Biol. 2015 Jan;35(2):344-55. doi: 10.1128/MCB.00926-14. Epub 2014 Nov 3.

8.

Retraction for Yoshimura et al., Distinct function of 2 chromatin remodeling complexes that share a common subunit, Williams syndrome transcription factor (WSTF).

Yoshimura K, Kitagawa H, Fujiki R, Tanabe M, Takezawa S, Takada I, Yamaoka I, Yonezawa M, Kondo T, Furutani Y, Yagi H, Yoshinaga S, Masuda T, Fukuda T, Yamamoto Y, Ebihara K, Li DY, Matsuoka R, Takeuchi JK, Matsumoto T, Kato S.

Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2398. doi: 10.1073/pnas.1323397111. Epub 2014 Jan 21. No abstract available.

9.

Nuclear receptors in bone physiology and diseases.

Imai Y, Youn MY, Inoue K, Takada I, Kouzmenko A, Kato S.

Physiol Rev. 2013 Apr;93(2):481-523. doi: 10.1152/physrev.00008.2012. Review.

10.

[Physiological functions of PPARs].

Takada I, Kato S.

Nihon Rinsho. 2012 Nov;70 Suppl 8:251-5. Japanese. No abstract available.

PMID:
23513846
11.

Structural Features and Transcriptional Activity of Chicken PPARs (α, β, and γ).

Takada I, Kobayashi M.

PPAR Res. 2013;2013:186312. doi: 10.1155/2013/186312. Epub 2013 Jan 3.

12.

Signaling Crosstalk between PPARγ and BMP2 in Mesenchymal Stem Cells.

Takada I, Yogiashi Y, Kato S.

PPAR Res. 2012;2012:607141. doi: 10.1155/2012/607141. Epub 2012 Dec 20.

13.

Epigenetic regulation of adipogenesis by PHF2 histone demethylase.

Okuno Y, Ohtake F, Igarashi K, Kanno J, Matsumoto T, Takada I, Kato S, Imai Y.

Diabetes. 2013 May;62(5):1426-34. doi: 10.2337/db12-0628. Epub 2012 Dec 28.

14.

Retraction: DNA demethylation in hormone-induced transcriptional derepression.

Kim MS, Kondo T, Takada I, Youn MY, Yamamoto Y, Takahashi S, Matsumoto T, Fujiyama S, Shirode Y, Yamaoka I, Kitagawa H, Takeyama K, Shibuya H, Ohtake F, Kato S.

Nature. 2012 Jun 13;486(7402):280. doi: 10.1038/nature11164. No abstract available.

PMID:
22699624
15.

Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain.

Shichita T, Hasegawa E, Kimura A, Morita R, Sakaguchi R, Takada I, Sekiya T, Ooboshi H, Kitazono T, Yanagawa T, Ishii T, Takahashi H, Mori S, Nishibori M, Kuroda K, Akira S, Miyake K, Yoshimura A.

Nat Med. 2012 Jun;18(6):911-7. doi: 10.1038/nm.2749.

PMID:
22610280
16.

[Switching of osteoblastogenesis versus adipogenesis].

Takada I.

Clin Calcium. 2012 May;22(5):629-36. doi: CliCa1205629636. Review. Japanese.

PMID:
22549186
17.

Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis.

Maeda K, Kobayashi Y, Udagawa N, Uehara S, Ishihara A, Mizoguchi T, Kikuchi Y, Takada I, Kato S, Kani S, Nishita M, Marumo K, Martin TJ, Minami Y, Takahashi N.

Nat Med. 2012 Feb 19;18(3):405-12. doi: 10.1038/nm.2653.

PMID:
22344299
18.

Smad2 and Smad3 are redundantly essential for the suppression of iNOS synthesis in macrophages by regulating IRF3 and STAT1 pathways.

Sugiyama Y, Kakoi K, Kimura A, Takada I, Kashiwagi I, Wakabayashi Y, Morita R, Nomura M, Yoshimura A.

Int Immunol. 2012 Apr;24(4):253-65. doi: 10.1093/intimm/dxr126. Epub 2012 Feb 13.

PMID:
22331441
19.

Contralateral glissonian pedicle occlusion in a case of portal vein tumor thrombosis.

Fukushima D, Sato K, Sekiguchi S, Kawagishi N, Akamatsu Y, Ogawa N, Takada I, Miyagi S, Kobayashi Y, Fujimori K, Satomi S.

Hepatogastroenterology. 2012 Jan-Feb;59(113):249-51. doi: 10.5754/hge11372.

PMID:
21940366
20.

Histone 3 lysine 9 (H3K9) methyltransferase recruitment to the interleukin-2 (IL-2) promoter is a mechanism of suppression of IL-2 transcription by the transforming growth factor-β-Smad pathway.

Wakabayashi Y, Tamiya T, Takada I, Fukaya T, Sugiyama Y, Inoue N, Kimura A, Morita R, Kashiwagi I, Takimoto T, Nomura M, Yoshimura A.

J Biol Chem. 2011 Oct 14;286(41):35456-65. doi: 10.1074/jbc.M111.236794. Epub 2011 Aug 23.

21.

Noncanonical Wnt signaling mediates androgen-dependent tumor growth in a mouse model of prostate cancer.

Takahashi S, Watanabe T, Okada M, Inoue K, Ueda T, Takada I, Watabe T, Yamamoto Y, Fukuda T, Nakamura T, Akimoto C, Fujimura T, Hoshino M, Imai Y, Metzger D, Miyazono K, Minami Y, Chambon P, Kitamura T, Matsumoto T, Kato S.

Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4938-43. doi: 10.1073/pnas.1014850108. Epub 2011 Mar 7.

22.

Identification of osteoclastic factors in the nuclear envelope of mature, multinucleated osteoclasts.

Youn MY, Fujiyama-Nakamura S, Takada I, Imai Y, Kato S.

Biosci Biotechnol Biochem. 2010;74(9):1956-9. Epub 2010 Sep 7.

23.

Transcriptionally active nuclei are selective in mature multinucleated osteoclasts.

Youn MY, Takada I, Imai Y, Yasuda H, Kato S.

Genes Cells. 2010 Oct;15(10):1025-35. doi: 10.1111/j.1365-2443.2010.01441.x. Epub 2010 Sep 10.

24.

PPAR-gamma Signaling Crosstalk in Mesenchymal Stem Cells.

Takada I, Kouzmenko AP, Kato S.

PPAR Res. 2010;2010. pii: 341671. doi: 10.1155/2010/341671. Epub 2010 Jul 26.

25.

Double PHD fingers protein DPF2 recognizes acetylated histones and suppresses the function of estrogen-related receptor alpha through histone deacetylase 1.

Matsuyama R, Takada I, Yokoyama A, Fujiyma-Nakamura S, Tsuji N, Kitagawa H, Fujiki R, Kim M, Kouzu-Fujita M, Yano T, Kato S.

J Biol Chem. 2010 Jun 11;285(24):18166-76. doi: 10.1074/jbc.M109.077024. Epub 2010 Apr 16. Retraction in: J Biol Chem. 2015 Feb 20;290(8):4816.

26.

Purification and identification of estrogen receptor alpha co-regulators in osteoclasts.

Takada I, Tsuji N, Youn MY, Fujiyama S, Okada M, Imai Y, Kondo S, Kitakawa H, Yasuda H, Kato S.

Ann N Y Acad Sci. 2010 Mar;1192:201-7. doi: 10.1111/j.1749-6632.2009.05215.x. Review.

PMID:
20392237
27.

[Structural insights of PPARgamma].

Kato S, Takada I.

Nihon Rinsho. 2010 Feb;68(2):176-9. Japanese. No abstract available.

PMID:
20158081
28.

SOCS3 in T and NKT cells negatively regulates cytokine production and ameliorates ConA-induced hepatitis.

Nakaya M, Hashimoto M, Nakagawa R, Wakabayashi Y, Ishizaki T, Takada I, Komai K, Yoshida H, Yoshimura A.

J Immunol. 2009 Dec 1;183(11):7047-53. doi: 10.4049/jimmunol.0900547. Epub 2009 Nov 13.

29.

CDP/cut is an osteoblastic coactivator of the vitamin D receptor (VDR).

Ochiai E, Kitagawa H, Takada I, Fujiyama S, Sawatsubashi S, Kim MS, Mezaki Y, Tsushima Y, Takagi K, Azuma Y, Takeyama K, Yamaoka K, Kato S, Kamimura T.

J Bone Miner Res. 2010 May;25(5):1157-66. doi: 10.1359/jbmr.091105. Retraction in: J Bone Miner Res. 2013 Feb;28(2):432.

30.

DNA demethylation in hormone-induced transcriptional derepression.

Kim MS, Kondo T, Takada I, Youn MY, Yamamoto Y, Takahashi S, Matsumoto T, Fujiyama S, Shirode Y, Yamaoka I, Kitagawa H, Takeyama K, Shibuya H, Ohtake F, Kato S.

Nature. 2009 Oct 15;461(7266):1007-12. doi: 10.1038/nature08456. Erratum in: Nature. 2011 Dec 1;480(7375):132. Retraction in: Kim MS, Kondo T, Takada I, Youn MY, Yamamoto Y, Takahashi S, Matsumoto T, Fujiyama S, Shirode Y, Yamaoka I, Kitagawa H, Takeyama K, Shibuya H, Ohtake F, Kato S. Nature. 2012 Jun 14;486(7402):280.

PMID:
19829383
31.

Phosphorylation of Williams syndrome transcription factor by MAPK induces a switching between two distinct chromatin remodeling complexes.

Oya H, Yokoyama A, Yamaoka I, Fujiki R, Yonezawa M, Youn MY, Takada I, Kato S, Kitagawa H.

J Biol Chem. 2009 Nov 20;284(47):32472-82. doi: 10.1074/jbc.M109.009738. Epub 2009 Sep 23. Retraction in: J Biol Chem. 2013 Oct 18;288(42):30508.

32.

Estrogens maintain bone mass by regulating expression of genes controlling function and life span in mature osteoclasts.

Imai Y, Youn MY, Kondoh S, Nakamura T, Kouzmenko A, Matsumoto T, Takada I, Takaoka K, Kato S.

Ann N Y Acad Sci. 2009 Sep;1173 Suppl 1:E31-9. doi: 10.1111/j.1749-6632.2009.04954.x.

PMID:
19751412
33.

Pivotal role of cerebral interleukin-17-producing gammadeltaT cells in the delayed phase of ischemic brain injury.

Shichita T, Sugiyama Y, Ooboshi H, Sugimori H, Nakagawa R, Takada I, Iwaki T, Okada Y, Iida M, Cua DJ, Iwakura Y, Yoshimura A.

Nat Med. 2009 Aug;15(8):946-50. doi: 10.1038/nm.1999. Epub 2009 Aug 2.

PMID:
19648929
34.

Wnt and PPARgamma signaling in osteoblastogenesis and adipogenesis.

Takada I, Kouzmenko AP, Kato S.

Nat Rev Rheumatol. 2009 Aug;5(8):442-7. doi: 10.1038/nrrheum.2009.137. Epub 2009 Jul 7. Review.

PMID:
19581903
35.

Distinct function of 2 chromatin remodeling complexes that share a common subunit, Williams syndrome transcription factor (WSTF).

Yoshimura K, Kitagawa H, Fujiki R, Tanabe M, Takezawa S, Takada I, Yamaoka I, Yonezawa M, Kondo T, Furutani Y, Yagi H, Yoshinaga S, Masuda T, Fukuda T, Yamamoto Y, Ebihara K, Li DY, Matsuoka R, Takeuchi JK, Matsumoto T, Kato S.

Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9280-5. doi: 10.1073/pnas.0901184106. Epub 2009 May 26. Retraction in: Yoshimura K, Kitagawa H, Fujiki R, Tanabe M, Takezawa S, Takada I, Yamaoka I, Yonezawa M, Kondo T, Furutani Y, Yagi H, Yoshinaga S, Masuda T, Fukuda T, Yamamoto Y, Ebihara K, Li DY, Matsuoka R, Takeuchi JK, Matsumoto T, Kato S. Proc Natl Acad Sci U S A. 20.

36.

Molecular switching of osteoblastogenesis versus adipogenesis: implications for targeted therapies.

Takada I, Kouzmenko AP, Kato S.

Expert Opin Ther Targets. 2009 May;13(5):593-603. doi: 10.1517/14728220902915310 . Review.

PMID:
19397478
37.

GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis.

Fujiki R, Chikanishi T, Hashiba W, Ito H, Takada I, Roeder RG, Kitagawa H, Kato S.

Nature. 2009 May 21;459(7245):455-9. doi: 10.1038/nature07954. Epub 2009 Apr 19. Retraction in: Nature. 2014 Jan 23;505(7484):574.

PMID:
19377461
38.

Switching of chromatin-remodelling complexes for oestrogen receptor-alpha.

Okada M, Takezawa S, Mezaki Y, Yamaoka I, Takada I, Kitagawa H, Kato S.

EMBO Rep. 2008 Jun;9(6):563-8. doi: 10.1038/embor.2008.55. Epub 2008 May 2. Retraction in: EMBO Rep. 2014 Dec;15(12):1330.

39.

[Molecular mechanism of switching adipocyte / osteoblast differentiation through regulation of PPAR-gamma function].

Takada I, Kato S.

Clin Calcium. 2008 May;18(5):656-61. doi: CliCa0805656661. Review. Japanese.

PMID:
18445885
40.

[Gene regulation by steroid receptors].

Takada I, Kato S.

Nihon Rinsho. 2008 Jan;66(1):65-9. Review. Japanese.

PMID:
18193545
41.

A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-gamma transactivation.

Takada I, Mihara M, Suzawa M, Ohtake F, Kobayashi S, Igarashi M, Youn MY, Takeyama K, Nakamura T, Mezaki Y, Takezawa S, Yogiashi Y, Kitagawa H, Yamada G, Takada S, Minami Y, Shibuya H, Matsumoto K, Kato S.

Nat Cell Biol. 2007 Nov;9(11):1273-85. Epub 2007 Oct 21. Erratum in: Nat Cell Biol. 2012 Dec;14(12):1345. Retraction in: Nat Cell Biol. 2014 Nov;16(11):1126.

PMID:
17952062
42.

Vitamin K induces osteoblast differentiation through pregnane X receptor-mediated transcriptional control of the Msx2 gene.

Igarashi M, Yogiashi Y, Mihara M, Takada I, Kitagawa H, Kato S.

Mol Cell Biol. 2007 Nov;27(22):7947-54. Epub 2007 Sep 17. Retraction in: Mol Cell Biol. 2014 Mar;34(5):918.

43.

Suppression of PPAR transactivation switches cell fate of bone marrow stem cells from adipocytes into osteoblasts.

Takada I, Suzawa M, Matsumoto K, Kato S.

Ann N Y Acad Sci. 2007 Nov;1116:182-95. Epub 2007 Jul 26. Review.

PMID:
17656564
44.

The pituitary function of androgen receptor constitutes a glucocorticoid production circuit.

Miyamoto J, Matsumoto T, Shiina H, Inoue K, Takada I, Ito S, Itoh J, Minematsu T, Sato T, Yanase T, Nawata H, Osamura YR, Kato S.

Mol Cell Biol. 2007 Jul;27(13):4807-14. Epub 2007 Apr 30. Erratum in: Mol Cell Biol. 2014 Mar;34(5):914.

45.

Dioxin receptor is a ligand-dependent E3 ubiquitin ligase.

Ohtake F, Baba A, Takada I, Okada M, Iwasaki K, Miki H, Takahashi S, Kouzmenko A, Nohara K, Chiba T, Fujii-Kuriyama Y, Kato S.

Nature. 2007 Mar 29;446(7135):562-6.

PMID:
17392787
46.

Id2 gene-targeted crosstalk between Wnt and retinoid signaling regulates proliferation in human keratinocytes.

Memezawa A, Takada I, Takeyama K, Igarashi M, Ito S, Aiba S, Kato S, Kouzmenko AP.

Oncogene. 2007 Aug 2;26(35):5038-45. Epub 2007 Feb 19.

PMID:
17310985
47.

A cell cycle-dependent co-repressor mediates photoreceptor cell-specific nuclear receptor function.

Takezawa S, Yokoyama A, Okada M, Fujiki R, Iriyama A, Yanagi Y, Ito H, Takada I, Kishimoto M, Miyajima A, Takeyama K, Umesono K, Kitagawa H, Kato S.

EMBO J. 2007 Feb 7;26(3):764-74. Epub 2007 Jan 25. Retraction in: EMBO J. 2014 Dec 1;33(23):2881.

48.

Culture serum-induced conversion from agonist to antagonist of a Vitamin D analog, TEI-9647.

Yamaoka K, Kim MS, Takada I, Takeyama K, Kamimura T, Kato S.

J Steroid Biochem Mol Biol. 2006 Aug;100(4-5):177-83. Epub 2006 Jul 10.

PMID:
16835013
49.

Premature ovarian failure in androgen receptor-deficient mice.

Shiina H, Matsumoto T, Sato T, Igarashi K, Miyamoto J, Takemasa S, Sakari M, Takada I, Nakamura T, Metzger D, Chambon P, Kanno J, Yoshikawa H, Kato S.

Proc Natl Acad Sci U S A. 2006 Jan 3;103(1):224-9. Epub 2005 Dec 22.

50.

Expression patterns of the chicken peroxisome proliferator-activated receptors (PPARs) during the development of the digestive organs.

Hojo M, Takada I, Kimura W, Fukuda K, Yasugi S.

Gene Expr Patterns. 2006 Jan;6(2):171-9. Epub 2005 Dec 1.

PMID:
16325478

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