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Items: 1 to 50 of 164

1.

Proximal Tubule Autophagy Differs in Type 1 and 2 Diabetes.

Sakai S, Yamamoto T, Takabatake Y, Takahashi A, Namba-Hamano T, Minami S, Fujimura R, Yonishi H, Matsuda J, Hesaka A, Matsui I, Matsusaka T, Niimura F, Yanagita M, Isaka Y.

J Am Soc Nephrol. 2019 Jun;30(6):929-945. doi: 10.1681/ASN.2018100983. Epub 2019 Apr 30.

PMID:
31040190
2.

A Randomized Trial of Magnesium Oxide and Oral Carbon Adsorbent for Coronary Artery Calcification in Predialysis CKD.

Sakaguchi Y, Hamano T, Obi Y, Monden C, Oka T, Yamaguchi S, Matsui I, Hashimoto N, Matsumoto A, Shimada K, Takabatake Y, Takahashi A, Kaimori JY, Moriyama T, Yamamoto R, Horio M, Yamamoto K, Sugimoto K, Rakugi H, Isaka Y.

J Am Soc Nephrol. 2019 Jun;30(6):1073-1085. doi: 10.1681/ASN.2018111150. Epub 2019 Apr 29.

PMID:
31036759
3.

Suppression of autophagic activity by Rubicon is a signature of aging.

Nakamura S, Oba M, Suzuki M, Takahashi A, Yamamuro T, Fujiwara M, Ikenaka K, Minami S, Tabata N, Yamamoto K, Kubo S, Tokumura A, Akamatsu K, Miyazaki Y, Kawabata T, Hamasaki M, Fukui K, Sango K, Watanabe Y, Takabatake Y, Kitajima TS, Okada Y, Mochizuki H, Isaka Y, Antebi A, Yoshimori T.

Nat Commun. 2019 Feb 19;10(1):847. doi: 10.1038/s41467-019-08729-6.

4.

VEGF-A Links Angiolymphoid Hyperplasia With Eosinophilia (ALHE) to THSD7A Membranous Nephropathy: A Report of 2 Cases.

Matsumoto A, Matsui I, Namba T, Sakaguchi Y, Mizuno H, Shirayama Y, Shimada K, Hashimoto N, Doi Y, Yamaguchi S, Kubota K, Oka T, Mori D, Akiyama S, Hamano T, Mizui M, Takabatake Y, Kaneko T, Isaka Y.

Am J Kidney Dis. 2019 Jun;73(6):880-885. doi: 10.1053/j.ajkd.2018.10.009. Epub 2018 Dec 13.

PMID:
30554801
5.

Inhibition of stromal cell-derived factor-1α/CXCR4 signaling restores the blood-retina barrier in pericyte-deficient mouse retinas.

Omori K, Nagata N, Kurata K, Fukushima Y, Sekihachi E, Fujii N, Namba-Hamano T, Takabatake Y, Fruttiger M, Nagasawa T, Uemura A, Murata T.

JCI Insight. 2018 Dec 6;3(23). pii: 120706. doi: 10.1172/jci.insight.120706.

6.

Severe Osteomalacia with Dent Disease Caused by a Novel Intronic Mutation of the CLCN5 gene.

Matsumoto A, Matsui I, Mori T, Sakaguchi Y, Mizui M, Ueda Y, Takahashi A, Doi Y, Shimada K, Yamaguchi S, Kubota K, Hashimoto N, Oka T, Takabatake Y, Sohara E, Hamano T, Uchida S, Isaka Y.

Intern Med. 2018 Dec 15;57(24):3603-3610. doi: 10.2169/internalmedicine.1272-18. Epub 2018 Aug 10.

7.

Proteinuria-associated renal magnesium wasting leads to hypomagnesemia: a common electrolyte abnormality in chronic kidney disease.

Oka T, Hamano T, Sakaguchi Y, Yamaguchi S, Kubota K, Senda M, Yonemoto S, Shimada K, Matsumoto A, Hashimoto N, Mori D, Monden C, Takahashi A, Obi Y, Yamamoto R, Takabatake Y, Kaimori JY, Moriyama T, Horio M, Matsui I, Isaka Y.

Nephrol Dial Transplant. 2018 May 22. doi: 10.1093/ndt/gfy119. [Epub ahead of print]

PMID:
29796601
8.

Cardiac hypertrophy elevates serum levels of fibroblast growth factor 23.

Matsui I, Oka T, Kusunoki Y, Mori D, Hashimoto N, Matsumoto A, Shimada K, Yamaguchi S, Kubota K, Yonemoto S, Higo T, Sakaguchi Y, Takabatake Y, Hamano T, Isaka Y.

Kidney Int. 2018 Jul;94(1):60-71. doi: 10.1016/j.kint.2018.02.018. Epub 2018 May 8.

PMID:
29751971
9.

Protein carbamylation exacerbates vascular calcification.

Mori D, Matsui I, Shimomura A, Hashimoto N, Matsumoto A, Shimada K, Yamaguchi S, Oka T, Kubota K, Yonemoto S, Sakaguchi Y, Takahashi A, Shintani Y, Takashima S, Takabatake Y, Hamano T, Isaka Y.

Kidney Int. 2018 Jul;94(1):72-90. doi: 10.1016/j.kint.2018.01.033. Epub 2018 Apr 30.

PMID:
29716796
10.

Hyperperfusion syndrome after trapping with high-flow bypass for a giant paraclinoid internal carotid artery aneurysm.

Mohri M, Ichinose T, Uchiyama N, Misaki K, Nambu I, Takabatake Y, Nakada M.

World Neurosurg. 2018 Jul;115:143-146. doi: 10.1016/j.wneu.2018.04.081. Epub 2018 Apr 22.

PMID:
29689406
11.

Antioxidant role of autophagy in maintaining the integrity of glomerular capillaries.

Matsuda J, Namba T, Takabatake Y, Kimura T, Takahashi A, Yamamoto T, Minami S, Sakai S, Fujimura R, Kaimori JY, Matsui I, Hamano T, Fukushima Y, Matsui K, Soga T, Isaka Y.

Autophagy. 2018;14(1):53-65. doi: 10.1080/15548627.2017.1391428.

12.

Lipophagy maintains energy homeostasis in the kidney proximal tubule during prolonged starvation.

Minami S, Yamamoto T, Takabatake Y, Takahashi A, Namba T, Matsuda J, Kimura T, Kaimori JY, Matsui I, Hamano T, Takeda H, Takahashi M, Izumi Y, Bamba T, Matsusaka T, Niimura F, Isaka Y.

Autophagy. 2017 Oct 3;13(10):1629-1647. doi: 10.1080/15548627.2017.1341464. Epub 2017 Aug 16.

13.

Radiation-induced gliomas: a report of four cases and analysis of molecular biomarkers.

Nakao T, Sasagawa Y, Nobusawa S, Takabatake Y, Sabit H, Kinoshita M, Miyashita K, Hayashi Y, Yokoo H, Nakada M.

Brain Tumor Pathol. 2017 Oct;34(4):149-154. doi: 10.1007/s10014-017-0292-x. Epub 2017 Aug 9.

PMID:
28795231
14.

The Authors Reply.

Hashimoto N, Matsui I, Namba T, Oka T, Mori D, Sakaguchi Y, Mizui M, Hamano T, Takabatake Y, Isaka Y.

Kidney Int. 2017 Apr;91(4):989-990. doi: 10.1016/j.kint.2016.11.021. No abstract available.

PMID:
28314583
15.

Autophagy Inhibits the Accumulation of Advanced Glycation End Products by Promoting Lysosomal Biogenesis and Function in the Kidney Proximal Tubules.

Takahashi A, Takabatake Y, Kimura T, Maejima I, Namba T, Yamamoto T, Matsuda J, Minami S, Kaimori JY, Matsui I, Matsusaka T, Niimura F, Yoshimori T, Isaka Y.

Diabetes. 2017 May;66(5):1359-1372. doi: 10.2337/db16-0397. Epub 2017 Feb 28.

16.

Stagnation of autophagy: A novel mechanism of renal lipotoxicity.

Takabatake Y, Yamamoto T, Isaka Y.

Autophagy. 2017 Apr 3;13(4):775-776. doi: 10.1080/15548627.2017.1283084. Epub 2017 Feb 6.

17.

Polymer-brush-afforded SPIO Nanoparticles Show a Unique Biodistribution and MR Imaging Contrast in Mouse Organs.

Chen T, Mori Y, Inui-Yamamoto C, Komai Y, Tago Y, Yoshida S, Takabatake Y, Isaka Y, Ohno K, Yoshioka Y.

Magn Reson Med Sci. 2017 Oct 10;16(4):275-283. doi: 10.2463/mrms.mp.2016-0067. Epub 2017 Jan 30.

18.

High-Fat Diet-Induced Lysosomal Dysfunction and Impaired Autophagic Flux Contribute to Lipotoxicity in the Kidney.

Yamamoto T, Takabatake Y, Takahashi A, Kimura T, Namba T, Matsuda J, Minami S, Kaimori JY, Matsui I, Matsusaka T, Niimura F, Yanagita M, Isaka Y.

J Am Soc Nephrol. 2017 May;28(5):1534-1551. doi: 10.1681/ASN.2016070731. Epub 2016 Dec 8.

19.

Association between Density of Coronary Artery Calcification and Serum Magnesium Levels among Patients with Chronic Kidney Disease.

Sakaguchi Y, Hamano T, Nakano C, Obi Y, Matsui I, Kusunoki Y, Mori D, Oka T, Hashimoto N, Takabatake Y, Takahashi A, Kaimori JY, Moriyama T, Yamamoto R, Horio M, Sugimoto K, Yamamoto K, Rakugi H, Isaka Y.

PLoS One. 2016 Sep 23;11(9):e0163673. doi: 10.1371/journal.pone.0163673. eCollection 2016.

20.

An unusual case of acute kidney injury after colonoscopy.

Hashimoto N, Matsui I, Namba T, Oka T, Mori D, Sakaguchi Y, Mizui M, Hamano T, Takabatake Y, Isaka Y.

Kidney Int. 2016 Sep;90(3):711. doi: 10.1016/j.kint.2016.06.024. No abstract available.

PMID:
27521123
21.

Time-dependent dysregulation of autophagy: Implications in aging and mitochondrial homeostasis in the kidney proximal tubule.

Yamamoto T, Takabatake Y, Kimura T, Takahashi A, Namba T, Matsuda J, Minami S, Kaimori JY, Matsui I, Kitamura H, Matsusaka T, Niimura F, Yanagita M, Isaka Y, Rakugi H.

Autophagy. 2016 May 3;12(5):801-13. doi: 10.1080/15548627.2016.1159376. Epub 2016 Mar 17.

22.

Lactation opposes pappalysin-1-driven pregnancy-associated breast cancer.

Takabatake Y, Oxvig C, Nagi C, Adelson K, Jaffer S, Schmidt H, Keely PJ, Eliceiri KW, Mandeli J, Germain D.

EMBO Mol Med. 2016 Apr 1;8(4):388-406. doi: 10.15252/emmm.201606273.

23.

Azilsartan Improves Salt Sensitivity by Modulating the Proximal Tubular Na+-H+ Exchanger-3 in Mice.

Hatanaka M, Kaimori JY, Yamamoto S, Matsui I, Hamano T, Takabatake Y, Ecelbarger CM, Takahara S, Isaka Y, Rakugi H.

PLoS One. 2016 Jan 25;11(1):e0147786. doi: 10.1371/journal.pone.0147786. eCollection 2016.

24.

Compound 48/80, a Mast Cell Stimulator, Enhances Synthesis of IgE and IgG Induced by Intranasal Application of Ovalbumin in Mice.

Matsui N, Ito D, Takabatake Y, Nashioka E, Tada S, Kanagawa M, Fukuishi N, Akagi M.

Biol Pharm Bull. 2015;38(12):1954-9. doi: 10.1248/bpb.b15-00637.

25.

Excess 25-hydroxyvitamin D3 exacerbates tubulointerstitial injury in mice by modulating macrophage phenotype.

Kusunoki Y, Matsui I, Hamano T, Shimomura A, Mori D, Yonemoto S, Takabatake Y, Tsubakihara Y, St-Arnaud R, Isaka Y, Rakugi H.

Kidney Int. 2015 Nov;88(5):1013-29. doi: 10.1038/ki.2015.210. Epub 2015 Jul 15.

PMID:
26176830
26.

Hyperuricemia-induced inflammasome and kidney diseases.

Isaka Y, Takabatake Y, Takahashi A, Saitoh T, Yoshimori T.

Nephrol Dial Transplant. 2016 Jun;31(6):890-6. doi: 10.1093/ndt/gfv024. Epub 2015 Mar 31. Review.

PMID:
25829326
27.

Emergent photovoltage on SmB6 surface upon bulk-gap evolution revealed by pump-and-probe photoemission spectroscopy.

Ishida Y, Otsu T, Shimada T, Okawa M, Kobayashi Y, Iga F, Takabatake T, Shin S.

Sci Rep. 2015 Feb 2;5:8160. doi: 10.1038/srep08160. Erratum in: Sci Rep. 2015;5:8955. Takabatake, Y [corrected to Takabatake, T].

28.

Histochemical and immunoelectron microscopic analysis of ganglioside GM3 in human kidney.

Kaneko T, Tsubakihara Y, Fushimi H, Yamaguchi S, Takabatake Y, Rakugi H, Kawakami H, Isaka Y.

Clin Exp Nephrol. 2015 Jun;19(3):403-10. doi: 10.1007/s10157-014-1003-0. Epub 2014 Jul 2.

PMID:
24985965
29.

Autophagic clearance of mitochondria in the kidney copes with metabolic acidosis.

Namba T, Takabatake Y, Kimura T, Takahashi A, Yamamoto T, Matsuda J, Kitamura H, Niimura F, Matsusaka T, Iwatani H, Matsui I, Kaimori J, Kioka H, Isaka Y, Rakugi H.

J Am Soc Nephrol. 2014 Oct;25(10):2254-66. doi: 10.1681/ASN.2013090986. Epub 2014 Apr 3.

30.

Dietary L-lysine prevents arterial calcification in adenine-induced uremic rats.

Shimomura A, Matsui I, Hamano T, Ishimoto T, Katou Y, Takehana K, Inoue K, Kusunoki Y, Mori D, Nakano C, Obi Y, Fujii N, Takabatake Y, Nakano T, Tsubakihara Y, Isaka Y, Rakugi H.

J Am Soc Nephrol. 2014 Sep;25(9):1954-65. doi: 10.1681/ASN.2013090967. Epub 2014 Mar 20.

31.

Circumvention of Mcl-1-dependent drug resistance by simultaneous Chk1 and MEK1/2 inhibition in human multiple myeloma cells.

Pei XY, Dai Y, Felthousen J, Chen S, Takabatake Y, Zhou L, Youssefian LE, Sanderson MW, Bodie WW, Kramer LB, Orlowski RZ, Grant S.

PLoS One. 2014 Mar 4;9(3):e89064. doi: 10.1371/journal.pone.0089064. eCollection 2014.

32.

Autophagy and the kidney: health and disease.

Takabatake Y, Kimura T, Takahashi A, Isaka Y.

Nephrol Dial Transplant. 2014 Sep;29(9):1639-47. doi: 10.1093/ndt/gft535. Epub 2014 Feb 10. Review.

PMID:
24520117
33.

Autophagy protects kidney proximal tubule epithelial cells from mitochondrial metabolic stress.

Kimura T, Takahashi A, Takabatake Y, Namba T, Yamamoto T, Kaimori JY, Matsui I, Kitamura H, Niimura F, Matsusaka T, Soga T, Rakugi H, Isaka Y.

Autophagy. 2013 Nov 1;9(11):1876-86. doi: 10.4161/auto.25418. Epub 2013 Jul 11.

PMID:
24128672
34.

Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury.

Maejima I, Takahashi A, Omori H, Kimura T, Takabatake Y, Saitoh T, Yamamoto A, Hamasaki M, Noda T, Isaka Y, Yoshimori T.

EMBO J. 2013 Aug 28;32(17):2336-47. doi: 10.1038/emboj.2013.171. Epub 2013 Aug 6.

35.

Renal transplantations from parents to siblings with autosomal recessive Alport syndrome caused by a rearrangement in an intronic antisense Alu element in the COL4A3 gene led to different outcomes.

Kaimori JY, Ichimaru N, Isaka Y, Hashimoto F, Fu X, Hashimura Y, Kaito H, Iijima K, Kyo M, Namba T, Obi Y, Hatanaka M, Matsui I, Takabatake Y, Okumi M, Yazawa K, Nonomura N, Rakugi H, Takahara S.

CEN Case Rep. 2013 May;2(1):98-101. doi: 10.1007/s13730-012-0049-7. Epub 2012 Dec 9.

36.

Response to letter regarding article, "incidence and clinical impact of stent fracture after everolimus-eluting stent implantation".

Kuramitsu S, Iwabuchi M, Domei T, Hyodo M, Yamaji K, Soga Y, Arita T, Shirai S, Kondo K, Ando K, Sakai K, Goya M, Yokoi H, Nosaka H, Nobuyoshi M, Haraguchi T, Nagae A, Takabatake Y, Toyota F, Sonoda S.

Circ Cardiovasc Interv. 2013 Feb;6(1):e10. doi: 10.1161/CIRCINTERVENTIONS.112.976068. No abstract available.

PMID:
23424273
37.

Retention of fetuin-A in renal tubular lumen protects the kidney from nephrocalcinosis in rats.

Matsui I, Hamano T, Mikami S, Inoue K, Shimomura A, Nagasawa Y, Michigami T, Ohnishi T, Fujii N, Nakano C, Kusunoki Y, Kitamura H, Iwatani H, Takabatake Y, Kaimori JY, Matsuba G, Okoshi K, Kimura-Suda H, Tsubakihara Y, Rakugi H, Isaka Y.

Am J Physiol Renal Physiol. 2013 Mar 15;304(6):F751-60. doi: 10.1152/ajprenal.00329.2012. Epub 2013 Jan 23.

38.

Chloroquine in cancer therapy: a double-edged sword of autophagy.

Kimura T, Takabatake Y, Takahashi A, Isaka Y.

Cancer Res. 2013 Jan 1;73(1):3-7. doi: 10.1158/0008-5472.CAN-12-2464. Review. Erratum in: Cancer Res. 2013 Feb 15;73(4):1446.

39.

Incidence and clinical impact of stent fracture after everolimus-eluting stent implantation.

Kuramitsu S, Iwabuchi M, Haraguchi T, Domei T, Nagae A, Hyodo M, Yamaji K, Soga Y, Arita T, Shirai S, Kondo K, Ando K, Sakai K, Goya M, Takabatake Y, Sonoda S, Yokoi H, Toyota F, Nosaka H, Nobuyoshi M.

Circ Cardiovasc Interv. 2012 Oct;5(5):663-71. doi: 10.1161/CIRCINTERVENTIONS.112.969238. Epub 2012 Sep 25.

PMID:
23011266
40.

Maxacalcitol ameliorates tubulointerstitial fibrosis in obstructed kidneys by recruiting PPM1A/VDR complex to pSmad3.

Inoue K, Matsui I, Hamano T, Fujii N, Shimomura A, Nakano C, Kusunoki Y, Takabatake Y, Hirata M, Nishiyama A, Tsubakihara Y, Isaka Y, Rakugi H.

Lab Invest. 2012 Dec;92(12):1686-97. doi: 10.1038/labinvest.2012.107. Epub 2012 Aug 27.

41.

[Autophagy and kidney aging].

Takabatake Y, Kimura T, Isaka Y.

Nihon Jinzo Gakkai Shi. 2012;54(2):78-85. Review. Japanese. No abstract available.

PMID:
22590960
42.

Use of xanthine oxidase inhibitor febuxostat inhibits renal interstitial inflammation and fibrosis in unilateral ureteral obstructive nephropathy.

Omori H, Kawada N, Inoue K, Ueda Y, Yamamoto R, Matsui I, Kaimori J, Takabatake Y, Moriyama T, Isaka Y, Rakugi H.

Clin Exp Nephrol. 2012 Aug;16(4):549-56. doi: 10.1007/s10157-012-0609-3. Epub 2012 Feb 18.

PMID:
22350467
43.

Autophagy guards against cisplatin-induced acute kidney injury.

Takahashi A, Kimura T, Takabatake Y, Namba T, Kaimori J, Kitamura H, Matsui I, Niimura F, Matsusaka T, Fujita N, Yoshimori T, Isaka Y, Rakugi H.

Am J Pathol. 2012 Feb;180(2):517-25. doi: 10.1016/j.ajpath.2011.11.001.

PMID:
22265049
44.

Towards developing new strategies to reduce the adverse side-effects of nonsteroidal anti-inflammatory drugs.

Kawada N, Moriyama T, Kitamura H, Yamamoto R, Furumatsu Y, Matsui I, Takabatake Y, Nagasawa Y, Imai E, Wilcox CS, Rakugi H, Isaka Y.

Clin Exp Nephrol. 2012 Feb;16(1):25-9. doi: 10.1007/s10157-011-0492-3. Epub 2011 Nov 1. Review.

PMID:
22038259
45.

Cytokinetically quiescent (G0/G1) human multiple myeloma cells are susceptible to simultaneous inhibition of Chk1 and MEK1/2.

Pei XY, Dai Y, Youssefian LE, Chen S, Bodie WW, Takabatake Y, Felthousen J, Almenara JA, Kramer LB, Dent P, Grant S.

Blood. 2011 Nov 10;118(19):5189-200. doi: 10.1182/blood-2011-02-339432. Epub 2011 Sep 12.

46.

The protective role of autophagy against aging and acute ischemic injury in kidney proximal tubular cells.

Isaka Y, Kimura T, Takabatake Y.

Autophagy. 2011 Sep;7(9):1085-7. Epub 2011 Sep 1.

PMID:
21606682
47.

Autophagy protects the proximal tubule from degeneration and acute ischemic injury.

Kimura T, Takabatake Y, Takahashi A, Kaimori JY, Matsui I, Namba T, Kitamura H, Niimura F, Matsusaka T, Soga T, Rakugi H, Isaka Y.

J Am Soc Nephrol. 2011 May;22(5):902-13. doi: 10.1681/ASN.2010070705. Epub 2011 Apr 14.

48.

A superagonistic monoclonal antibody for CD28 ameliorates crescentic glomerulonephritis in wistar-kyoto rats.

Takabatake Y, Li XK, Mizui M, Miyasato K, Matsui I, Kawada N, Imai E, Hünig T, Takahara S, Wada T, Furuichi K, Rakugi H, Isaka Y.

Mol Med. 2011;17(7-8):686-96. doi: 10.2119/molmed.2010.00229. Epub 2011 Apr 8.

49.

Induction of donor-specific tolerance using superagonistic CD28 antibody in rat renal allografts: regulatory T-cell expansion before engraftment may be important.

Azuma H, Isaka Y, Nomi H, Inamoto T, Li XK, Hounig T, Takabatake Y, Ichimaru N, Ibuki N, Matsumoto K, Ubai T, Katsuoka Y, Takahara S.

Transplantation. 2010 Dec 27;90(12):1328-35. doi: 10.1097/TP.0b013e3182007b59.

PMID:
21085062
50.

CD28 superagonist-induced regulatory T cell expansion ameliorates mesangioproliferative glomerulonephritis in rats.

Miyasato K, Takabatake Y, Kaimori J, Kimura T, Kitamura H, Kawachi H, Li XK, Hünig T, Takahara S, Rakugi H, Isaka Y.

Clin Exp Nephrol. 2011 Feb;15(1):50-7. doi: 10.1007/s10157-010-0370-4. Epub 2010 Nov 16.

PMID:
21076989

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