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Items: 1 to 50 of 56

1.

ANO7 is associated with aggressive prostate cancer.

Kaikkonen E, Rantapero T, Zhang Q, Taimen P, Laitinen V, Kallajoki M, Jambulingam D, Ettala O, Knaapila J, Boström PJ, Wahlström G, Sipeky C, Pursiheimo JP, Tammela T, Kellokumpu-Lehtinen PL; PRACTICAL Consortium, Fey V, Maehle L, Wiklund F, Wei GH, Schleutker J.

Int J Cancer. 2018 Nov 15;143(10):2479-2487. doi: 10.1002/ijc.31746. Epub 2018 Sep 22.

PMID:
30157291
2.

11C-acetate PET/MRI in bladder cancer staging and treatment response evaluation to neoadjuvant chemotherapy: a prospective multicenter study (ACEBIB trial).

Salminen A, Jambor I, Merisaari H, Ettala O, Virtanen J, Koskinen I, Veskimae E, Sairanen J, Taimen P, Kemppainen J, Minn H, Boström PJ.

Cancer Imaging. 2018 Aug 2;18(1):25. doi: 10.1186/s40644-018-0158-4.

3.

Urine cytology is a feasible tool for assessing erythematous bladder lesions after bacille Calmette-Guérin (BCG) treatment.

Nurminen P, Ettala O, Seppänen M, Taimen P, Boström PJ, Kaipia A.

BJU Int. 2019 Feb;123(2):246-251. doi: 10.1111/bju.14470. Epub 2018 Aug 12.

PMID:
29959824
4.

Intratumoral androgen levels are linked to TMPRSS2-ERG fusion in prostate cancer.

Knuuttila M, Mehmood A, Mäki-Jouppila J, Ryberg H, Taimen P, Knaapila J, Ettala O, Boström PJ, Ohlsson C, Venäläinen MS, Laiho A, Elo LL, Sipilä P, Mäkelä SI, Poutanen M.

Endocr Relat Cancer. 2018 Sep;25(9):807-819. doi: 10.1530/ERC-18-0148. Epub 2018 May 17.

PMID:
29773553
5.

Radiomic features from pretreatment biparametric MRI predict prostate cancer biochemical recurrence: Preliminary findings.

Shiradkar R, Ghose S, Jambor I, Taimen P, Ettala O, Purysko AS, Madabhushi A.

J Magn Reson Imaging. 2018 Dec;48(6):1626-1636. doi: 10.1002/jmri.26178. Epub 2018 May 7.

PMID:
29734484
6.

The composition of prostate core matrisome in vivo and in vitro unveiled by mass spectrometric analysis.

Ojalill M, Rappu P, Siljamäki E, Taimen P, Boström P, Heino J.

Prostate. 2018 Jun;78(8):583-594. doi: 10.1002/pros.23503. Epub 2018 Mar 9.

PMID:
29520855
7.

Pegylated and liposomal doxorubicin is associated with high mortality and causes limited cardiotoxicity in mice.

Stark C, Taimen P, Savunen T, Koskenvuo J.

BMC Res Notes. 2018 Feb 21;11(1):148. doi: 10.1186/s13104-018-3260-6.

8.

New prostate cancer grade grouping system predicts survival after radical prostatectomy.

Erickson A, Sandeman K, Lahdensuo K, Nordling S, Kallajoki M, Seikkula H, Bützow A, Vasarainen H, Boström PJ, Taimen P, Rannikko A, Mirtti T.

Hum Pathol. 2018 May;75:159-166. doi: 10.1016/j.humpath.2018.01.027. Epub 2018 Feb 13. No abstract available.

9.

Prospective evaluation of 18F-FACBC PET/CT and PET/MRI versus multiparametric MRI in intermediate- to high-risk prostate cancer patients (FLUCIPRO trial).

Jambor I, Kuisma A, Kähkönen E, Kemppainen J, Merisaari H, Eskola O, Teuho J, Perez IM, Pesola M, Aronen HJ, Boström PJ, Taimen P, Minn H.

Eur J Nucl Med Mol Imaging. 2018 Mar;45(3):355-364. doi: 10.1007/s00259-017-3875-1. Epub 2017 Nov 16.

PMID:
29147764
10.

Immunological tumor status may predict response to neoadjuvant chemotherapy and outcome after radical cystectomy in bladder cancer.

Tervahartiala M, Taimen P, Mirtti T, Koskinen I, Ecke T, Jalkanen S, Boström PJ.

Sci Rep. 2017 Oct 4;7(1):12682. doi: 10.1038/s41598-017-12892-5.

11.

Internal epithelia in Drosophila display rudimentary competence to form cytoplasmic networks of transgenic human vimentin.

Gullmets J, Torvaldson E, Lindqvist J, Imanishi SY, Taimen P, Meinander A, Eriksson JE.

FASEB J. 2017 Dec;31(12):5332-5341. doi: 10.1096/fj.201700332R. Epub 2017 Aug 4.

PMID:
28778974
12.

Nestin contributes to skeletal muscle homeostasis and regeneration.

Lindqvist J, Torvaldson E, Gullmets J, Karvonen H, Nagy A, Taimen P, Eriksson JE.

J Cell Sci. 2017 Sep 1;130(17):2833-2842. doi: 10.1242/jcs.202226. Epub 2017 Jul 21.

13.

Novel biparametric MRI and targeted biopsy improves risk stratification in men with a clinical suspicion of prostate cancer (IMPROD Trial).

Jambor I, Boström PJ, Taimen P, Syvänen K, Kähkönen E, Kallajoki M, Perez IM, Kauko T, Matomäki J, Ettala O, Merisaari H, Kiviniemi A, Dean PB, Aronen HJ.

J Magn Reson Imaging. 2017 Oct;46(4):1089-1095. doi: 10.1002/jmri.25641. Epub 2017 Feb 6.

PMID:
28165653
14.

Radiomic features for prostate cancer detection on MRI differ between the transition and peripheral zones: Preliminary findings from a multi-institutional study.

Ginsburg SB, Algohary A, Pahwa S, Gulani V, Ponsky L, Aronen HJ, Boström PJ, Böhm M, Haynes AM, Brenner P, Delprado W, Thompson J, Pulbrock M, Taimen P, Villani R, Stricker P, Rastinehad AR, Jambor I, Madabhushi A.

J Magn Reson Imaging. 2017 Jul;46(1):184-193. doi: 10.1002/jmri.25562. Epub 2016 Dec 19.

15.

Loss of PTEN expression in ERG-negative prostate cancer predicts secondary therapies and leads to shorter disease-specific survival time after radical prostatectomy.

Lahdensuo K, Erickson A, Saarinen I, Seikkula H, Lundin J, Lundin M, Nordling S, Bützow A, Vasarainen H, Boström PJ, Taimen P, Rannikko A, Mirtti T.

Mod Pathol. 2016 Dec;29(12):1565-1574. doi: 10.1038/modpathol.2016.154. Epub 2016 Aug 26.

16.

Correction: Validation of Novel Biomarkers for Prostate Cancer Progression by the Combination of Bioinformatics, Clinical and Functional Studies.

Alinezhad S, Väänänen RM, Mattsson J, Li Y, Tallgrén T, Tong Ochoa N, Bjartell A, Åkerfelt M, Taimen P, Boström PJ, Pettersson K, Nees M.

PLoS One. 2016 Jun 21;11(6):e0158255. doi: 10.1371/journal.pone.0158255. eCollection 2016.

17.

Patient-specific pharmacokinetic parameter estimation on dynamic contrast-enhanced MRI of prostate: Preliminary evaluation of a novel AIF-free estimation method.

Ginsburg SB, Taimen P, Merisaari H, Vainio P, Boström PJ, Aronen HJ, Jambor I, Madabhushi A.

J Magn Reson Imaging. 2016 Dec;44(6):1405-1414. doi: 10.1002/jmri.25330. Epub 2016 Jun 10.

18.

Deleterious assembly of the lamin A/C mutant p.S143P causes ER stress in familial dilated cardiomyopathy.

West G, Gullmets J, Virtanen L, Li SP, Keinänen A, Shimi T, Mauermann M, Heliö T, Kaartinen M, Ollila L, Kuusisto J, Eriksson JE, Goldman RD, Herrmann H, Taimen P.

J Cell Sci. 2016 Jul 15;129(14):2732-43. doi: 10.1242/jcs.184150. Epub 2016 May 27.

19.

Keratin 8-deletion induced colitis predisposes to murine colorectal cancer enforced by the inflammasome and IL-22 pathway.

Misiorek JO, Lähdeniemi IAK, Nyström JH, Paramonov VM, Gullmets JA, Saarento H, Rivero-Müller A, Husøy T, Taimen P, Toivola DM.

Carcinogenesis. 2016 Aug;37(8):777-786. doi: 10.1093/carcin/bgw063. Epub 2016 May 27.

PMID:
27234655
20.

Systemic Dosing of Thymosin Beta 4 before and after Ischemia Does Not Attenuate Global Myocardial Ischemia-Reperfusion Injury in Pigs.

Stark CK, Tarkia M, Kentala R, Malmberg M, Vähäsilta T, Savo M, Hynninen VV, Helenius M, Ruohonen S, Jalkanen J, Taimen P, Alastalo TP, Saraste A, Knuuti J, Savunen T, Koskenvuo J.

Front Pharmacol. 2016 May 3;7:115. doi: 10.3389/fphar.2016.00115. eCollection 2016.

21.

Validation of Novel Biomarkers for Prostate Cancer Progression by the Combination of Bioinformatics, Clinical and Functional Studies.

Alinezhad S, Väänänen RM, Mattsson J, Li Y, Tallgrén T, Tong Ochoa N, Bjartell A, Åkerfelt M, Taimen P, Boström PJ, Pettersson K, Nees M.

PLoS One. 2016 May 19;11(5):e0155901. doi: 10.1371/journal.pone.0155901. eCollection 2016. Erratum in: PLoS One. 2016;11(6):e0158255.

22.

Global expression of AMACR transcripts predicts risk for prostate cancer - a systematic comparison of AMACR protein and mRNA expression in cancerous and noncancerous prostate.

Alinezhad S, Väänänen RM, Ochoa NT, Vertosick EA, Bjartell A, Boström PJ, Taimen P, Pettersson K.

BMC Urol. 2016 Feb 29;16:10. doi: 10.1186/s12894-016-0128-8.

23.

Fitting methods for intravoxel incoherent motion imaging of prostate cancer on region of interest level: Repeatability and gleason score prediction.

Merisaari H, Movahedi P, Perez IM, Toivonen J, Pesola M, Taimen P, Boström PJ, Pahikkala T, Kiviniemi A, Aronen HJ, Jambor I.

Magn Reson Med. 2017 Mar;77(3):1249-1264. doi: 10.1002/mrm.26169. Epub 2016 Feb 28.

PMID:
26924552
24.

Increased expression of fibroblast growth factor 13 in prostate cancer is associated with shortened time to biochemical recurrence after radical prostatectomy.

Yu L, Toriseva M, Tuomala M, Seikkula H, Elo T, Tuomela J, Kallajoki M, Mirtti T, Taimen P, Boström PJ, Alanen K, Nurmi M, Nees M, Härkönen P.

Int J Cancer. 2016 Jul 1;139(1):140-52. doi: 10.1002/ijc.30048. Epub 2016 Mar 12.

25.

Stratification of aggressive prostate cancer from indolent disease-Prospective controlled trial utilizing expression of 11 genes in apparently benign tissue.

Alinezhad S, Väänänen RM, Tallgrén T, Perez IM, Jambor I, Aronen H, Kähkönen E, Ettala O, Syvänen K, Nees M, Kallajoki M, Taimen P, Boström PJ, Pettersson K.

Urol Oncol. 2016 Jun;34(6):255.e15-22. doi: 10.1016/j.urolonc.2015.12.014. Epub 2016 Feb 5.

PMID:
26857646
26.

Differential Predictive Roles of A- and B-Type Nuclear Lamins in Prostate Cancer Progression.

Saarinen I, Mirtti T, Seikkula H, Boström PJ, Taimen P.

PLoS One. 2015 Oct 15;10(10):e0140671. doi: 10.1371/journal.pone.0140671. eCollection 2015.

27.

Altered PCA3 and TMPRSS2-ERG expression in histologically benign regions of cancerous prostates: a systematic, quantitative mRNA analysis in five prostates.

Väänänen RM, Ochoa NT, Boström PJ, Taimen P, Pettersson K.

BMC Urol. 2015 Aug 21;15:88. doi: 10.1186/s12894-015-0077-7.

28.

Diffusion-weighted imaging of prostate cancer: effect of b-value distribution on repeatability and cancer characterization.

Merisaari H, Toivonen J, Pesola M, Taimen P, Boström PJ, Pahikkala T, Aronen HJ, Jambor I.

Magn Reson Imaging. 2015 Dec;33(10):1212-1218. doi: 10.1016/j.mri.2015.07.004. Epub 2015 Jul 26.

PMID:
26220861
29.

Tumor-Associated Macrophages Provide Significant Prognostic Information in Urothelial Bladder Cancer.

Boström MM, Irjala H, Mirtti T, Taimen P, Kauko T, Ålgars A, Jalkanen S, Boström PJ.

PLoS One. 2015 Jul 21;10(7):e0133552. doi: 10.1371/journal.pone.0133552. eCollection 2015.

30.

Relaxation along fictitious field, diffusion-weighted imaging, and T2 mapping of prostate cancer: Prediction of cancer aggressiveness.

Jambor I, Pesola M, Merisaari H, Taimen P, Boström PJ, Liimatainen T, Aronen HJ.

Magn Reson Med. 2016 May;75(5):2130-40. doi: 10.1002/mrm.25808. Epub 2015 Jun 22.

PMID:
26094849
31.

Suppression of endothelial CD39/ENTPD1 is associated with pulmonary vascular remodeling in pulmonary arterial hypertension.

Helenius MH, Vattulainen S, Orcholski M, Aho J, Komulainen A, Taimen P, Wang L, de Jesus Perez VA, Koskenvuo JW, Alastalo TP.

Am J Physiol Lung Cell Mol Physiol. 2015 May 15;308(10):L1046-57. doi: 10.1152/ajplung.00340.2014. Epub 2015 Mar 27.

32.

LMNA Mutation c.917T>G (p.L306R) Leads to Deleterious Hyper-Assembly of Lamin A/C and Associates with Severe Right Ventricular Cardiomyopathy and Premature Aging.

Alastalo TP, West G, Li SP, Keinänen A, Helenius M, Tyni T, Lapatto R, Turanlahti M, Heikkilä P, Kääriäinen H, Laakso M, Mauermann M, Herrmann H, Pihkala J, Taimen P.

Hum Mutat. 2015 Jul;36(7):694-703. doi: 10.1002/humu.22793. Epub 2015 Jun 1.

PMID:
25820511
33.

Gene-rich chromosomal regions are preferentially localized in the lamin B deficient nuclear blebs of atypical progeria cells.

Bercht Pfleghaar K, Taimen P, Butin-Israeli V, Shimi T, Langer-Freitag S, Markaki Y, Goldman AE, Wehnert M, Goldman RD.

Nucleus. 2015;6(1):66-76. doi: 10.1080/19491034.2015.1004256. Erratum in: Nucleus. 2015;6(3):247.

34.

Rotating frame relaxation imaging of prostate cancer: Repeatability, cancer detection, and Gleason score prediction.

Jambor I, Pesola M, Taimen P, Merisaari H, Boström PJ, Minn H, Liimatainen T, Aronen HJ.

Magn Reson Med. 2016 Jan;75(1):337-44. doi: 10.1002/mrm.25647. Epub 2015 Mar 2.

PMID:
25733132
35.

Role of ultrasensitive prostate-specific antigen in the follow-up of prostate cancer after radical prostatectomy.

Seikkula H, Syvänen KT, Kurki S, Mirtti T, Taimen P, Laato M, Boström PJ.

Urol Oncol. 2014 Nov 18. pii: S1078-1439(14)00353-6. doi: 10.1016/j.urolonc.2014.10.010. [Epub ahead of print]

PMID:
25456996
36.

Mathematical models for diffusion-weighted imaging of prostate cancer using b values up to 2000 s/mm(2) : correlation with Gleason score and repeatability of region of interest analysis.

Toivonen J, Merisaari H, Pesola M, Taimen P, Boström PJ, Pahikkala T, Aronen HJ, Jambor I.

Magn Reson Med. 2015 Oct;74(4):1116-24. doi: 10.1002/mrm.25482. Epub 2014 Oct 20.

PMID:
25329932
37.

Evaluation of different mathematical models for diffusion-weighted imaging of normal prostate and prostate cancer using high b-values: a repeatability study.

Jambor I, Merisaari H, Taimen P, Boström P, Minn H, Pesola M, Aronen HJ.

Magn Reson Med. 2015 May;73(5):1988-98. doi: 10.1002/mrm.25323. Epub 2014 Jul 12.

PMID:
25046482
38.

Prebiopsy multiparametric 3T prostate MRI in patients with elevated PSA, normal digital rectal examination, and no previous biopsy.

Jambor I, Kähkönen E, Taimen P, Merisaari H, Saunavaara J, Alanen K, Obsitnik B, Minn H, Lehotska V, Aronen HJ.

J Magn Reson Imaging. 2015 May;41(5):1394-404. doi: 10.1002/jmri.24682. Epub 2014 Jun 23.

PMID:
24956412
39.

Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis.

Arjonen A, Kaukonen R, Mattila E, Rouhi P, Högnäs G, Sihto H, Miller BW, Morton JP, Bucher E, Taimen P, Virtakoivu R, Cao Y, Sansom OJ, Joensuu H, Ivaska J.

J Clin Invest. 2014 Mar;124(3):1069-82.

40.

Loss of bone morphogenetic protein receptor 2 is associated with abnormal DNA repair in pulmonary arterial hypertension.

Li M, Vattulainen S, Aho J, Orcholski M, Rojas V, Yuan K, Helenius M, Taimen P, Myllykangas S, De Jesus Perez V, Koskenvuo JW, Alastalo TP.

Am J Respir Cell Mol Biol. 2014 Jun;50(6):1118-28. doi: 10.1165/rcmb.2013-0349OC.

PMID:
24433082
41.

Bulbourethral gland adenocarcinoma in a 25-year-old man without comorbidities: radical resection of proximal urethrae with Mitrofanoff-type appendicovesicostomy.

Syvänen KT, Taimen P, Salminen A, Kuusisto K, Boström PJ.

Scand J Urol. 2014 Aug;48(4):405-9. doi: 10.3109/21681805.2013.852622. Epub 2013 Nov 11.

PMID:
24215360
42.

Lanthanide chelate complementation and hydrolysis enhanced luminescent chelate in real-time reverse transcription polymerase chain reaction assays for KLK3 transcripts.

Alinezhad S, Väänänen RM, Lehmusvuori A, Karhunen U, Soukka T, Kähkönen E, Taimen P, Alanen K, Pettersson K.

Anal Biochem. 2014 Jan 1;444:1-7. doi: 10.1016/j.ab.2013.09.020. Epub 2013 Sep 29.

PMID:
24084379
43.

Therapeutic potential of thymosin β4 in myocardial infarct and heart failure.

Stark C, Taimen P, Tarkia M, Pärkkä J, Saraste A, Alastalo TP, Savunen T, Koskenvuo J.

Ann N Y Acad Sci. 2012 Oct;1269:117-24. doi: 10.1111/j.1749-6632.2012.06695.x.

PMID:
23045979
44.

Topical cis-urocanic acid attenuates oedema and erythema in acute and subacute skin inflammation in the mouse.

Laihia JK, Taimen P, Kujari H, Leino L.

Br J Dermatol. 2012 Sep;167(3):506-13. doi: 10.1111/j.1365-2133.2012.11026.x. Epub 2012 Jul 19.

PMID:
22540389
45.

Chromosomal regions associated with prostate cancer risk localize to lamin B-deficient microdomains and exhibit reduced gene transcription.

Helfand BT, Wang Y, Pfleghaar K, Shimi T, Taimen P, Shumaker DK.

J Pathol. 2012 Apr;226(5):735-45. doi: 10.1002/path.3033. Epub 2012 Jan 17.

PMID:
22025297
46.

Nuclear lamins.

Dechat T, Adam SA, Taimen P, Shimi T, Goldman RD.

Cold Spring Harb Perspect Biol. 2010 Nov;2(11):a000547. doi: 10.1101/cshperspect.a000547. Epub 2010 Sep 8. Review.

47.

Protodynamic intracellular acidification by cis-urocanic acid promotes apoptosis of melanoma cells in vitro and in vivo.

Laihia JK, Kallio JP, Taimen P, Kujari H, Kähäri VM, Leino L.

J Invest Dermatol. 2010 Oct;130(10):2431-9. doi: 10.1038/jid.2010.151. Epub 2010 Jun 3.

48.

Silencing of Nuclear Mitotic Apparatus protein (NuMA) accelerates the apoptotic disintegration of the nucleus.

Kivinen K, Taimen P, Kallajoki M.

Apoptosis. 2010 Aug;15(8):936-45. doi: 10.1007/s10495-010-0506-8.

PMID:
20467816
49.

A progeria mutation reveals functions for lamin A in nuclear assembly, architecture, and chromosome organization.

Taimen P, Pfleghaar K, Shimi T, Möller D, Ben-Harush K, Erdos MR, Adam SA, Herrmann H, Medalia O, Collins FS, Goldman AE, Goldman RD.

Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20788-93. doi: 10.1073/pnas.0911895106. Epub 2009 Nov 19.

50.

Cardiac tamponade in a patient with predominantly cutaneous manifestations of primary antiphospholipid syndrome.

Liippo J, Taimen P, Talve L, Saario R, Vainio E.

Acta Derm Venereol. 2008;88(2):162-3. doi: 10.2340/00015555-0344. No abstract available.

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