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Items: 1 to 50 of 189

1.

Molecules and Mechanisms Underlying the Antimicrobial Activity of Escapin, an l-Amino Acid Oxidase from the Ink of Sea Hares.

Derby CD, Gilbert ES, Tai PC.

Biol Bull. 2018 Aug;235(1):52-61. doi: 10.1086/699175. Epub 2018 Jul 30.

PMID:
30160994
2.

SecA inhibitors as potential antimicrobial agents: differential actions on SecA-only and SecA-SecYEG protein-conducting channels.

Jin J, Hsieh YH, Chaudhary AS, Cui J, Houghton JE, Sui SF, Wang B, Tai PC.

FEMS Microbiol Lett. 2018 Aug 1;365(15). doi: 10.1093/femsle/fny145. Review.

PMID:
30007321
3.

Dissecting structures and functions of SecA-only protein-conducting channels: ATPase, pore structure, ion channel activity, protein translocation, and interaction with SecYEG/SecDF•YajC.

Hsieh YH, Huang YJ, Zhang H, Liu Q, Lu Y, Yang H, Houghton J, Jiang C, Sui SF, Tai PC.

PLoS One. 2017 Jun 2;12(6):e0178307. doi: 10.1371/journal.pone.0178307. eCollection 2017.

4.

Biphasic actions of SecA inhibitors on Prl/Sec suppressors: Possible physiological roles of SecA-only channels.

Hsieh YH, Zhang H, Jin J, Dai C, Jiang C, Wang B, Tai PC.

Biochem Biophys Res Commun. 2017 Jan 8;482(2):296-300. doi: 10.1016/j.bbrc.2016.11.057. Epub 2016 Nov 14.

PMID:
27856243
5.

Using Chemical Probes to Assess the Feasibility of Targeting SecA for Developing Antimicrobial Agents against Gram-Negative Bacteria.

Jin J, Hsieh YH, Cui J, Damera K, Dai C, Chaudhary AS, Zhang H, Yang H, Cao N, Jiang C, Vaara M, Wang B, Tai PC.

ChemMedChem. 2016 Nov 21;11(22):2511-2521. doi: 10.1002/cmdc.201600421. Epub 2016 Oct 18.

6.

Meningioangiomatosis: A Disease With Many Radiological Faces.

Nascimento FA, Kiehl TR, Tai PC, Valiante TA, Krings T.

Can J Neurol Sci. 2016 Nov;43(6):847-849. Epub 2016 Sep 9. No abstract available.

PMID:
27609048
7.

Inhibition and Dispersal of Pseudomonas aeruginosa Biofilms by Combination Treatment with Escapin Intermediate Products and Hydrogen Peroxide.

Santiago AJ, Ahmed MN, Wang SL, Damera K, Wang B, Tai PC, Gilbert ES, Derby CD.

Antimicrob Agents Chemother. 2016 Aug 22;60(9):5554-62. doi: 10.1128/AAC.02984-15. Print 2016 Sep.

8.

Design, Synthesis and Evaluation of Triazole-Pyrimidine Analogues as SecA Inhibitors.

Cui J, Jin J, Chaudhary AS, Hsieh YH, Zhang H, Dai C, Damera K, Chen W, Tai PC, Wang B.

ChemMedChem. 2016 Jan 5;11(1):43-56. doi: 10.1002/cmdc.201500447. Epub 2015 Nov 26.

9.

Evaluation of small molecule SecA inhibitors against methicillin-resistant Staphylococcus aureus.

Jin J, Cui J, Chaudhary AS, Hsieh YH, Damera K, Zhang H, Yang H, Wang B, Tai PC.

Bioorg Med Chem. 2015 Nov 1;23(21):7061-8. doi: 10.1016/j.bmc.2015.09.027. Epub 2015 Sep 21.

10.

Meningitis and Reversible Cerebral Vasoconstriction Syndrome During the Postpartum Period.

Boulos MI, Wortsman J, Swartz RH, Tai PC, Casaubon LK, Lazarou J.

Can J Neurol Sci. 2015 Sep;42(5):341-3. doi: 10.1017/cjn.2015.268. Epub 2015 Aug 19. No abstract available.

PMID:
26286264
11.

SecA: a potential antimicrobial target.

Chaudhary AS, Chen W, Jin J, Tai PC, Wang B.

Future Med Chem. 2015;7(8):989-1007. doi: 10.4155/fmc.15.42. Review.

12.

Monitoring channel activities of proteoliposomes with SecA and Cx26 gap junction in single oocytes.

Hsieh YH, Zou J, Jin JS, Yang H, Chen Y, Jiang C, Yang J, Tai PC.

Anal Biochem. 2015 Jul 1;480:58-66. doi: 10.1016/j.ab.2015.04.005. Epub 2015 Apr 8.

PMID:
25862083
13.

Design, syntheses and evaluation of 4-oxo-5-cyano thiouracils as SecA inhibitors.

Chaudhary AS, Jin J, Chen W, Tai PC, Wang B.

Bioorg Med Chem. 2015 Jan 1;23(1):105-17. doi: 10.1016/j.bmc.2014.11.017. Epub 2014 Nov 20.

PMID:
25498235
14.

Mechanisms of Rose Bengal inhibition on SecA ATPase and ion channel activities.

Hsieh YH, Huang YJ, Jin JS, Yu L, Yang H, Jiang C, Wang B, Tai PC.

Biochem Biophys Res Commun. 2014 Nov 14;454(2):308-12. doi: 10.1016/j.bbrc.2014.10.070. Epub 2014 Oct 19.

15.

Characterization of the minimal length of functional SecA in Escherichia coli.

Na B, You Z, Yang H, Tai PC.

Biochem Biophys Res Commun. 2015 Jan 2;456(1):213-8. doi: 10.1016/j.bbrc.2014.11.061. Epub 2014 Nov 22.

16.

The dispensability and requirement of SecA N-terminal aminoacyl residues for complementation, membrane binding, lipid-specific domains and channel activities.

Floyd JH, You Z, Hsieh YH, Ma Y, Yang H, Tai PC.

Biochem Biophys Res Commun. 2014 Oct 10;453(1):138-42. doi: 10.1016/j.bbrc.2014.09.080. Epub 2014 Sep 27.

17.

SecAAA trimer is fully functional as SecAA dimer in the membrane: existence of higher oligomers?

Wang H, Ma Y, Hsieh YH, Yang H, Li M, Wang B, Tai PC.

Biochem Biophys Res Commun. 2014 May 2;447(2):250-4. doi: 10.1016/j.bbrc.2014.03.116. Epub 2014 Apr 1.

18.

An internal hydrophobic helical domain of Bacillus subtilis enolase is essential but not sufficient as a non-cleavable signal for its secretion.

Yang CK, Zhang XZ, Lu CD, Tai PC.

Biochem Biophys Res Commun. 2014 Apr 18;446(4):901-5. doi: 10.1016/j.bbrc.2014.03.032. Epub 2014 Mar 15.

19.

Phospholipids induce conformational changes of SecA to form membrane-specific domains: AFM structures and implication on protein-conducting channels.

You Z, Liao M, Zhang H, Yang H, Pan X, Houghton JE, Sui SF, Tai PC.

PLoS One. 2013 Aug 16;8(8):e72560. doi: 10.1371/journal.pone.0072560. eCollection 2013.

20.

Time-related transcriptome analysis of B. subtilis 168 during growth with glucose.

Yang CK, Tai PC, Lu CD.

Curr Microbiol. 2014 Jan;68(1):12-20. doi: 10.1007/s00284-013-0432-4. Epub 2013 Aug 10.

PMID:
23934352
21.
22.

Design, synthesis and biological evaluation of rose bengal analogues as SecA inhibitors.

Cui J, Jin J, Hsieh YH, Yang H, Ke B, Damera K, Tai PC, Wang B.

ChemMedChem. 2013 Aug;8(8):1384-93. doi: 10.1002/cmdc.201300216. Epub 2013 Jun 21.

PMID:
23794293
23.

Specificity of SecYEG for PhoA precursors and SecA homologs on SecA protein-conducting channels.

Zhang H, Hsieh YH, Lin BR, Yu L, Yang H, Jiang C, Sui SF, Tai PC.

Biochem Biophys Res Commun. 2013 Jul 26;437(2):212-216. doi: 10.1016/j.bbrc.2013.06.039. Epub 2013 Jun 20.

24.

Reconstitution of functionally efficient SecA-dependent protein-conducting channels: transformation of low-affinity SecA-liposome channels to high-affinity SecA-SecYEG-SecDF·YajC channels.

Hsieh YH, Zhang H, Wang H, Yang H, Jiang C, Sui SF, Tai PC.

Biochem Biophys Res Commun. 2013 Feb 15;431(3):388-92. doi: 10.1016/j.bbrc.2013.01.042. Epub 2013 Jan 18.

PMID:
23337498
25.

Escherichia coli membranes depleted of SecYEG elicit SecA-dependent ion-channel activity but lose signal peptide specificity.

Lin BR, Hsieh YH, Jiang C, Tai PC.

J Membr Biol. 2012 Nov;245(11):747-57. doi: 10.1007/s00232-012-9477-8. Epub 2012 Aug 2.

PMID:
22854753
26.

Mutational analysis of Cvab, an ABC transporter involved in the secretion of active colicin V.

Wu KH, Hsieh YH, Tai PC.

PLoS One. 2012;7(4):e35382. doi: 10.1371/journal.pone.0035382. Epub 2012 Apr 23.

27.

Fluorescein analogues inhibit SecA ATPase: the first sub-micromolar inhibitor of bacterial protein translocation.

Huang YJ, Wang H, Gao FB, Li M, Yang H, Wang B, Tai PC.

ChemMedChem. 2012 Apr;7(4):571-7. doi: 10.1002/cmdc.201100594. Epub 2012 Feb 22.

29.

SecA alone can promote protein translocation and ion channel activity: SecYEG increases efficiency and signal peptide specificity.

Hsieh YH, Zhang H, Lin BR, Cui N, Na B, Yang H, Jiang C, Sui SF, Tai PC.

J Biol Chem. 2011 Dec 30;286(52):44702-9. doi: 10.1074/jbc.M111.300111. Epub 2011 Oct 27.

30.

Nonclassical protein secretion by Bacillus subtilis in the stationary phase is not due to cell lysis.

Yang CK, Ewis HE, Zhang X, Lu CD, Hu HJ, Pan Y, Abdelal AT, Tai PC.

J Bacteriol. 2011 Oct;193(20):5607-15. doi: 10.1128/JB.05897-11. Epub 2011 Aug 19.

31.

Understandable learning machine system design for transmembrane or embedded membrane segments prediction.

Hu HJ, Harrison RW, Tai PC, Pan Y.

Int J Data Min Bioinform. 2011;5(1):38-51.

PMID:
21491843
32.

Distribution and function of splash, an achaete-scute homolog in the adult olfactory organ of the Caribbean spiny lobster Panulirus argus.

Tadesse T, Schmidt M, Walthall WW, Tai PC, Derby CD.

Dev Neurobiol. 2011 Apr;71(4):316-35. doi: 10.1002/dneu.20862.

33.

Dimeric SecA couples the preprotein translocation in an asymmetric manner.

Tang Y, Pan X, Chen Y, Tai PC, Sui SF.

PLoS One. 2011 Jan 27;6(1):e16498. doi: 10.1371/journal.pone.0016498.

34.

Electron microscopic visualization of asymmetric precursor translocation intermediates: SecA functions as a dimer.

Tang Y, Pan X, Tai PC, Sui S.

Sci China Life Sci. 2010 Sep;53(9):1049-56. doi: 10.1007/s11427-010-4061-x. Epub 2010 Nov 23.

PMID:
21104364
35.

The structure of SecB/OmpA as visualized by electron microscopy: The mature region of the precursor protein binds asymmetrically to SecB.

Tang Y, Pan X, Tai PC, Sui SF.

Biochem Biophys Res Commun. 2010 Mar 19;393(4):698-702. doi: 10.1016/j.bbrc.2010.02.062. Epub 2010 Feb 17.

PMID:
20170640
36.

The first low microM SecA inhibitors.

Chen W, Huang YJ, Gundala SR, Yang H, Li M, Tai PC, Wang B.

Bioorg Med Chem. 2010 Feb 15;18(4):1617-25. doi: 10.1016/j.bmc.2009.12.074. Epub 2010 Jan 6.

37.

Novel efficient granular computing models for protein sequence motifs and structure information discovery.

Chen B, Pellicer S, Tai PC, Harrison R, Pan Y.

Int J Comput Biol Drug Des. 2009;2(2):168-86. doi: 10.1504/IJCBDD.2009.028822. Epub 2009 Oct 3.

PMID:
20090169
38.

Synthesis and evaluation of new antagonists of bacterial quorum sensing in Vibrio harveyi.

Peng H, Cheng Y, Ni N, Li M, Choudhary G, Chou HT, Lu CD, Tai PC, Wang B.

ChemMedChem. 2009 Sep;4(9):1457-68. doi: 10.1002/cmdc.200900180.

PMID:
19533733
39.

Molecular cloning and characterization of homologs of achaete-scute and hairy-enhancer of split in the olfactory organ of the spiny lobster Panulirus argus.

Chien H, Tadesse T, Liu H, Schmidt M, Walthall WW, Tai PC, Derby CD.

J Mol Neurosci. 2009 Sep;39(1-2):294-307. doi: 10.1007/s12031-009-9195-6. Epub 2009 Mar 26.

PMID:
19322682
40.

[Influence of early effective control for inflammatory exudation on survival rate of acute paraquat poisoning].

Tai PC, Zhang YZ, Zhou YJ.

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2009 Jan;27(1):48. Chinese. No abstract available.

PMID:
19224697
41.

The chemistry of escapin: identification and quantification of the components in the complex mixture generated by an L-amino acid oxidase in the defensive secretion of the sea snail Aplysia californica.

Kamio M, Ko KC, Zheng S, Wang B, Collins SL, Gadda G, Tai PC, Derby CD.

Chemistry. 2009;15(7):1597-603. doi: 10.1002/chem.200801696.

PMID:
19130530
42.

Identification of potent bactericidal compounds produced by escapin, an L-amino acid oxidase in the ink of the sea hare Aplysia californica.

Ko KC, Wang B, Tai PC, Derby CD.

Antimicrob Agents Chemother. 2008 Dec;52(12):4455-62. doi: 10.1128/AAC.01103-08. Epub 2008 Oct 13.

43.

Full-length Escherichia coli SecA dimerizes in a closed conformation in solution as determined by cryo-electron microscopy.

Chen Y, Pan X, Tang Y, Quan S, Tai PC, Sui SF.

J Biol Chem. 2008 Oct 24;283(43):28783-7. doi: 10.1074/jbc.C800160200. Epub 2008 Sep 4.

44.

Structure-based discovery and experimental verification of novel AI-2 quorum sensing inhibitors against Vibrio harveyi.

Li M, Ni N, Chou HT, Lu CD, Tai PC, Wang B.

ChemMedChem. 2008 Aug;3(8):1242-9. doi: 10.1002/cmdc.200800076.

PMID:
18537200
45.

Identification of boronic acids as antagonists of bacterial quorum sensing in Vibrio harveyi.

Ni N, Chou HT, Wang J, Li M, Lu CD, Tai PC, Wang B.

Biochem Biophys Res Commun. 2008 May 2;369(2):590-4. doi: 10.1016/j.bbrc.2008.02.061. Epub 2008 Feb 22.

PMID:
18295599
46.

Discovery of the first SecA inhibitors using structure-based virtual screening.

Li M, Huang YJ, Tai PC, Wang B.

Biochem Biophys Res Commun. 2008 Apr 18;368(4):839-45. doi: 10.1016/j.bbrc.2008.01.135. Epub 2008 Feb 7.

PMID:
18261984
47.

Structure of Bacillus subtilis superoxide dismutase.

Liu P, Ewis HE, Huang YJ, Lu CD, Tai PC, Weber IT.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Dec 1;63(Pt 12):1003-7. Epub 2007 Nov 21.

49.

A new seed selection algorithm that maximizes local structural similarity in proteins.

Altun G, Zhong W, Pan Y, Tai PC, Harrison RW.

Conf Proc IEEE Eng Med Biol Soc. 2006;1:5822-5.

PMID:
17946336
50.

To be or not to be: predicting soluble SecAs as membrane proteins.

Hu HJ, Holley J, He J, Harrison RW, Yang H, Tai PC, Pan Y.

IEEE Trans Nanobioscience. 2007 Jun;6(2):168-79.

PMID:
17695753

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