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Items: 1 to 50 of 133

1.

Targeting Proteases in Cystic Fibrosis Lung Disease: Paradigms, Progress, and Potential.

McKelvey MC, Weldon S, McAuley DF, Mall MA, Taggart CC.

Am J Respir Crit Care Med. 2019 Oct 18. doi: 10.1164/rccm.201906-1190PP. [Epub ahead of print]

PMID:
31626562
2.

Lack of IL-1 Receptor Signaling Reduces Spontaneous Airway Eosinophilia in Juvenile Mice with Muco-Obstructive Lung Disease.

Brown R, Paulsen M, Schmidt S, Schatterny J, Frank A, Hirtz S, Delaney R, Doherty D, Hagner M, Taggart C, Weldon S, Mall MA.

Am J Respir Cell Mol Biol. 2019 Sep 9. doi: 10.1165/rcmb.2018-0359OC. [Epub ahead of print]

PMID:
31499011
3.

Alginate/Chitosan Particle-Based Drug Delivery Systems for Pulmonary Applications.

Hill M, Twigg M, Sheridan EA, Hardy JG, Elborn JS, Taggart CC, Scott CJ, Migaud ME.

Pharmaceutics. 2019 Aug 2;11(8). pii: E379. doi: 10.3390/pharmaceutics11080379.

4.

Evaluation of BacterioScan 216Dx in Comparison to Urinalysis as a Screening Tool for Diagnosis of Urinary Tract Infections in Children.

Hassan F, Bushnell H, Taggart C, Gibbs C, Hiraki S, Formanek A, Gripka M, Selvarangan R.

J Clin Microbiol. 2019 Aug 26;57(9). pii: e00571-19. doi: 10.1128/JCM.00571-19. Print 2019 Sep.

PMID:
31217269
5.

Sea snake cathelicidin (Hc-cath) exerts a protective effect in mouse models of lung inflammation and infection.

Carlile SR, Shiels J, Kerrigan L, Delaney R, Megaw J, Gilmore BF, Weldon S, Dalton JP, Taggart CC.

Sci Rep. 2019 Apr 15;9(1):6071. doi: 10.1038/s41598-019-42537-8.

6.

A Pilot Study of Human Milk to Reduce Intestinal Inflammation After Bone Marrow Transplant.

Khandelwal P, Andersen H, Romick-Rosendale L, Taggart CB, Watanabe M, Lane A, Dandoy CE, Lake KE, Litts BA, Morrow AL, Lee ML, Haslam DB, Davies SM.

Breastfeed Med. 2019 Apr;14(3):193-202. doi: 10.1089/bfm.2018.0199. Epub 2019 Mar 27.

PMID:
30916575
7.

Comparing a Neutropenic Diet to a Food Safety-Based Diet in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation.

Taggart C, Neumann N, Alonso PB, Lane A, Pate A, Stegman A, Stendahl A, Davies SM, Dandoy CE, Grimley M.

Biol Blood Marrow Transplant. 2019 Jul;25(7):1382-1386. doi: 10.1016/j.bbmt.2019.03.017. Epub 2019 Mar 22.

PMID:
30910605
8.

Variation in egg mass within two Atlantic herring Clupea harengus stocks.

Óskarsson GJ, Taggart CT, Stephenson RL.

J Fish Biol. 2019 Aug;95(2):367-378. doi: 10.1111/jfb.13956. Epub 2019 Apr 12.

PMID:
30900244
9.

Respiratory viral infection: a potential "missing link" in the pathogenesis of COPD.

Linden D, Guo-Parke H, Coyle PV, Fairley D, McAuley DF, Taggart CC, Kidney J.

Eur Respir Rev. 2019 Mar 14;28(151). pii: 180063. doi: 10.1183/16000617.0063-2018. Print 2019 Mar 31. Review.

10.

Targeting of cathepsin S reduces cystic fibrosis-like lung disease.

Small DM, Brown RR, Doherty DF, Abladey A, Zhou-Suckow Z, Delaney RJ, Kerrigan L, Dougan CM, Borensztajn KS, Holsinger L, Booth R, Scott CJ, López-Campos G, Elborn JS, Mall MA, Weldon S, Taggart CC.

Eur Respir J. 2019 Mar 28;53(3). pii: 1801523. doi: 10.1183/13993003.01523-2018. Print 2019 Mar.

PMID:
30655278
11.

Protein Phosphatase 2A Reduces Cigarette Smoke-induced Cathepsin S and Loss of Lung Function.

Doherty DF, Nath S, Poon J, Foronjy RF, Ohlmeyer M, Dabo AJ, Salathe M, Birrell M, Belvisi M, Baumlin N, Kim MD, Weldon S, Taggart C, Geraghty P.

Am J Respir Crit Care Med. 2019 Jul 1;200(1):51-62. doi: 10.1164/rccm.201808-1518OC.

PMID:
30641028
12.

Preclinical Evaluation of Dose-Volume Effects and Lung Toxicity Occurring In and Out-of-Field.

Ghita M, Dunne VL, McMahon SJ, Osman SO, Small DM, Weldon S, Taggart CC, McGarry CK, Hounsell AR, Graves EE, Prise KM, Hanna GG, Butterworth KT.

Int J Radiat Oncol Biol Phys. 2019 Apr 1;103(5):1231-1240. doi: 10.1016/j.ijrobp.2018.12.010. Epub 2018 Dec 12.

PMID:
30552964
13.

Modernising the Mental Health Act: getting the balance right.

Lynch G, Campbell P, Taggart C.

Lancet. 2018 Dec 15;392(10164):2532-2534. doi: 10.1016/S0140-6736(18)33140-4. Epub 2018 Dec 7. No abstract available.

PMID:
30528658
14.

Nanodelivery strategies for the treatment of multidrug-resistant bacterial infections.

Jiang L, Lin J, Taggart CC, Bengoechea JA, Scott CJ.

J Interdiscip Nanomed. 2018 Sep 4;3(3):111-121. doi: 10.1002/jin2.48. eCollection 2018 Sep. Review.

15.

Systolic and Diastolic Blood Pressure Variability as Risk Factors for Adverse Events After Coronary Artery Bypass Grafting.

Dyke CM, Benz CL, Taggart CM, Klug MG, Basson MD.

JAMA Surg. 2019 Jan 1;154(1):92-94. doi: 10.1001/jamasurg.2018.3233. No abstract available.

16.

Proteases and Their Inhibitors in Chronic Obstructive Pulmonary Disease.

Dey T, Kalita J, Weldon S, Taggart CC.

J Clin Med. 2018 Aug 28;7(9). pii: E244. doi: 10.3390/jcm7090244. Review.

17.

Single Ultra-High-Dose Cholecalciferol to Prevent Vitamin D Deficiency in Pediatric Hematopoietic Stem Cell Transplantation.

Wallace G, Jodele S, Myers KC, Dandoy CE, El-Bietar J, Nelson A, Teusink-Cross A, Khandelwal P, Taggart C, Gordon CM, Davies SM, Howell JC.

Biol Blood Marrow Transplant. 2018 Sep;24(9):1856-1860. doi: 10.1016/j.bbmt.2018.05.019. Epub 2018 May 18.

18.

Clearance of intracellular Klebsiella pneumoniae infection using gentamicin-loaded nanoparticles.

Jiang L, Greene MK, Insua JL, Pessoa JS, Small DM, Smyth P, McCann AP, Cogo F, Bengoechea JA, Taggart CC, Scott CJ.

J Control Release. 2018 Jun 10;279:316-325. doi: 10.1016/j.jconrel.2018.04.040. Epub 2018 Apr 25.

PMID:
29704616
19.

Elastase activity on sputum neutrophils correlates with severity of lung disease in cystic fibrosis.

Dittrich AS, Kühbandner I, Gehrig S, Rickert-Zacharias V, Twigg M, Wege S, Taggart CC, Herth F, Schultz C, Mall MA.

Eur Respir J. 2018 Mar 29;51(3). pii: 1701910. doi: 10.1183/13993003.01910-2017. Print 2018 Mar.

20.

The parasitic 68-mer peptide FhHDM-1 inhibits mixed granulocytic inflammation and airway hyperreactivity in experimental asthma.

Tanaka A, Allam VSRR, Simpson J, Tiberti N, Shiels J, To J, Lund M, Combes V, Weldon S, Taggart C, Dalton JP, Phipps S, Sukkar MB, Donnelly S.

J Allergy Clin Immunol. 2018 Jun;141(6):2316-2319. doi: 10.1016/j.jaci.2018.01.050. Epub 2018 Mar 6. No abstract available.

PMID:
29522851
21.

Cystic fibrosis epithelial cells are primed for apoptosis as a result of increased Fas (CD95).

Chen Q, Pandi SPS, Kerrigan L, McElvaney NG, Greene CM, Elborn JS, Taggart CC, Weldon S.

J Cyst Fibros. 2018 Sep;17(5):616-623. doi: 10.1016/j.jcf.2018.01.010. Epub 2018 Mar 2.

PMID:
29486923
22.

Mental Capacity Act (Northern Ireland) 2016.

Lynch G, Taggart C, Campbell P.

BJPsych Bull. 2017 Dec;41(6):353-357. doi: 10.1192/pb.bp.117.056945. Review.

23.

Characterisation of eppin function: expression and activity in the lung.

Scott A, Glasgow A, Small D, Carlile S, McCrudden M, McLean D, Brown R, Doherty D, Lundy FT, Hamid UI, O'Kane CM, McAuley DF, Brodlie M, Tunney M, Elborn JS, Irwin CR, Timson DJ, Taggart CC, Weldon S.

Eur Respir J. 2017 Jul 13;50(1). pii: 1601937. doi: 10.1183/13993003.01937-2016. Print 2017 Jul.

24.

Inhibition of ataxia telangiectasia related-3 (ATR) improves therapeutic index in preclinical models of non-small cell lung cancer (NSCLC) radiotherapy.

Dunne V, Ghita M, Small DM, Coffey CBM, Weldon S, Taggart CC, Osman SO, McGarry CK, Prise KM, Hanna GG, Butterworth KT.

Radiother Oncol. 2017 Sep;124(3):475-481. doi: 10.1016/j.radonc.2017.06.025. Epub 2017 Jul 8.

PMID:
28697853
25.

Activity of innate antimicrobial peptides and ivacaftor against clinical cystic fibrosis respiratory pathogens.

Payne JE, Dubois AV, Ingram RJ, Weldon S, Taggart CC, Elborn JS, Tunney MM.

Int J Antimicrob Agents. 2017 Sep;50(3):427-435. doi: 10.1016/j.ijantimicag.2017.04.014. Epub 2017 Jun 27.

PMID:
28666755
26.

Biomarkers to monitor exacerbations in cystic fibrosis.

Gray RD, Downey D, Taggart CC.

Expert Rev Respir Med. 2017 Apr;11(4):255-257. doi: 10.1080/17476348.2017.1307739. No abstract available.

PMID:
28299964
27.

Lower levels of vitamin A are associated with increased gastrointestinal graft-versus-host disease in children.

Lounder DT, Khandelwal P, Dandoy CE, Jodele S, Grimley MS, Wallace G, Lane A, Taggart C, Teusink-Cross AC, Lake KE, Davies SM.

Blood. 2017 May 18;129(20):2801-2807. doi: 10.1182/blood-2017-02-765826. Epub 2017 Mar 9.

28.

Protean proteases: at the cutting edge of lung diseases.

Taggart C, Mall MA, Lalmanach G, Cataldo D, Ludwig A, Janciauskiene S, Heath N, Meiners S, Overall CM, Schultz C, Turk B, Borensztajn KS.

Eur Respir J. 2017 Feb 8;49(2). pii: 1501200. doi: 10.1183/13993003.01200-2015. Print 2017 Feb. Review.

29.

The role of whey acidic protein four-disulfide-core proteins in respiratory health and disease.

Small DM, Doherty DF, Dougan CM, Weldon S, Taggart CC.

Biol Chem. 2017 Apr 1;398(4):425-440. doi: 10.1515/hsz-2016-0262. Review.

PMID:
27930359
30.

Neutrophil elastase cleaves epithelial cadherin in acutely injured lung epithelium.

Boxio R, Wartelle J, Nawrocki-Raby B, Lagrange B, Malleret L, Hirche T, Taggart C, Pacheco Y, Devouassoux G, Bentaher A.

Respir Res. 2016 Oct 17;17(1):129.

31.

Shortness of breath: Looking beyond the usual suspects.

Taggart C.

J Fam Pract. 2016 Aug;65(8):526-33.

PMID:
27660836
32.

Vitamin D Deficiency in Pediatric Hematopoietic Stem Cell Transplantation Patients Despite Both Standard and Aggressive Supplementation.

Wallace G, Jodele S, Myers KC, Dandoy CE, El-Bietar J, Nelson A, Taggart CB, Daniels P, Lane A, Howell J, Teusink-Cross A, Davies SM.

Biol Blood Marrow Transplant. 2016 Jul;22(7):1271-1274. doi: 10.1016/j.bbmt.2016.03.026. Epub 2016 Apr 1.

33.

Measuring abnormal movements in free-swimming fish with accelerometers: implications for quantifying tag and parasite load.

Broell F, Burnell C, Taggart CT.

J Exp Biol. 2016 Mar;219(Pt 5):695-705. doi: 10.1242/jeb.133033. Epub 2016 Jan 8.

34.

Scaling in Free-Swimming Fish and Implications for Measuring Size-at-Time in the Wild.

Broell F, Taggart CT.

PLoS One. 2015 Dec 16;10(12):e0144875. doi: 10.1371/journal.pone.0144875. eCollection 2015.

35.

Sensory Processing and Its Relationship with Children's Daily Life Participation.

Chien CW, Rodger S, Copley J, Branjerdporn G, Taggart C.

Phys Occup Ther Pediatr. 2016;36(1):73-87. doi: 10.3109/01942638.2015.1040573. Epub 2015 Sep 30.

PMID:
26422598
36.

A secretory leukocyte protease inhibitor variant with improved activity against lung infection.

Camper N, Glasgow AM, Osbourn M, Quinn DJ, Small DM, McLean DT, Lundy FT, Elborn JS, McNally P, Ingram RJ, Weldon S, Taggart CC.

Mucosal Immunol. 2016 May;9(3):669-76. doi: 10.1038/mi.2015.90. Epub 2015 Sep 16.

PMID:
26376365
37.

The Ability of Secretory Leukocyte Protease Inhibitor to Inhibit Apoptosis in Monocytes Is Independent of Its Antiprotease Activity.

McGarry N, Greene CM, McElvaney NG, Weldon S, Taggart CC.

J Immunol Res. 2015;2015:507315. doi: 10.1155/2015/507315. Epub 2015 Jul 12.

38.

The Role of Serine Proteases and Antiproteases in the Cystic Fibrosis Lung.

Twigg MS, Brockbank S, Lowry P, FitzGerald SP, Taggart C, Weldon S.

Mediators Inflamm. 2015;2015:293053. doi: 10.1155/2015/293053. Epub 2015 Jun 21. Review.

39.

A Missed Opportunity.

Rozen L, Duff K, Taggart C, Scott J.

J Infus Nurs. 2015 Jul-Aug;38(4):252-3. doi: 10.1097/NAN.0000000000000115. No abstract available.

PMID:
26126137
40.

Vitamin D Deficiency and Survival in Children after Hematopoietic Stem Cell Transplant.

Wallace G, Jodele S, Howell J, Myers KC, Teusink A, Zhao X, Setchell K, Holtzapfel C, Lane A, Taggart C, Laskin BL, Davies SM.

Biol Blood Marrow Transplant. 2015 Sep;21(9):1627-31. doi: 10.1016/j.bbmt.2015.06.009. Epub 2015 Jun 18.

41.

Genetic structure of capelin (Mallotus villosus) in the northwest Atlantic Ocean.

Kenchington EL, Nakashima BS, Taggart CT, Hamilton LC.

PLoS One. 2015 Mar 30;10(3):e0122315. doi: 10.1371/journal.pone.0122315. eCollection 2015.

42.

A role for whey acidic protein four-disulfide-core 12 (WFDC12) in the regulation of the inflammatory response in the lung.

Glasgow AM, Small DM, Scott A, McLean DT, Camper N, Hamid U, Hegarty S, Parekh D, O'Kane C, Lundy FT, McNally P, Elborn JS, McAuley DF, Weldon S, Taggart CC.

Thorax. 2015 May;70(5):426-32. doi: 10.1136/thoraxjnl-2014-206488. Epub 2015 Mar 13.

PMID:
25770093
43.

Antimicrobial efficacy of tobramycin polymeric nanoparticles for Pseudomonas aeruginosa infections in cystic fibrosis: formulation, characterisation and functionalisation with dornase alfa (DNase).

Deacon J, Abdelghany SM, Quinn DJ, Schmid D, Megaw J, Donnelly RF, Jones DS, Kissenpfennig A, Elborn JS, Gilmore BF, Taggart CC, Scott CJ.

J Control Release. 2015 Jan 28;198:55-61. doi: 10.1016/j.jconrel.2014.11.022. Epub 2014 Dec 4.

PMID:
25481442
44.

Long distance linkage disequilibrium and limited hybridization suggest cryptic speciation in atlantic cod.

Bradbury IR, Bowman S, Borza T, Snelgrove PV, Hutchings JA, Berg PR, Rodríguez-Ezpeleta N, Lighten J, Ruzzante DE, Taggart C, Bentzen P.

PLoS One. 2014 Sep 26;9(9):e106380. doi: 10.1371/journal.pone.0106380. eCollection 2014.

45.

A functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation.

Small DM, Zani ML, Quinn DJ, Dallet-Choisy S, Glasgow AM, O'Kane C, McAuley DF, McNally P, Weldon S, Moreau T, Taggart CC.

Mol Ther. 2015 Jan;23(1):24-31. doi: 10.1038/mt.2014.162. Epub 2014 Sep 5.

46.

A longitudinal analysis of drinking and victimization in college women: is there a reciprocal relationship?

Parks KA, Hsieh YP, Taggart C, Bradizza CM.

Psychol Addict Behav. 2014 Dec;28(4):943-51. doi: 10.1037/a0036283. Epub 2014 Aug 18.

47.

Type-I interferons induce lung protease responses following respiratory syncytial virus infection via RIG-I-like receptors.

Foronjy RF, Taggart CC, Dabo AJ, Weldon S, Cummins N, Geraghty P.

Mucosal Immunol. 2015 Jan;8(1):161-75. doi: 10.1038/mi.2014.54. Epub 2014 Jul 9.

48.

miR-31 dysregulation in cystic fibrosis airways contributes to increased pulmonary cathepsin S production.

Weldon S, McNally P, McAuley DF, Oglesby IK, Wohlford-Lenane CL, Bartlett JA, Scott CJ, McElvaney NG, Greene CM, McCray PB Jr, Taggart CC.

Am J Respir Crit Care Med. 2014 Jul 15;190(2):165-74. doi: 10.1164/rccm.201311-1986OC.

49.

Keratinocyte growth factor promotes epithelial survival and resolution in a human model of lung injury.

Shyamsundar M, McAuley DF, Ingram RJ, Gibson DS, O'Kane D, McKeown ST, Edwards A, Taggart C, Elborn JS, Calfee CS, Matthay MA, O'Kane CM.

Am J Respir Crit Care Med. 2014 Jun 15;189(12):1520-9. doi: 10.1164/rccm.201310-1892OC.

50.

Respiratory syncytial virus infections enhance cigarette smoke induced COPD in mice.

Foronjy RF, Dabo AJ, Taggart CC, Weldon S, Geraghty P.

PLoS One. 2014 Feb 28;9(2):e90567. doi: 10.1371/journal.pone.0090567. eCollection 2014.

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