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Items: 32


Uneven distribution of cobamide biosynthesis and dependence in bacteria predicted by comparative genomics.

Shelton AN, Seth EC, Mok KC, Han AW, Jackson SN, Haft DR, Taga ME.

ISME J. 2019 Mar;13(3):789-804. doi: 10.1038/s41396-018-0304-9. Epub 2018 Nov 14.


Unique Biochemical and Sequence Features Enable BluB To Destroy Flavin and Distinguish BluB from the Flavin Monooxygenase Superfamily.

Hazra AB, Ballou DP, Taga ME.

Biochemistry. 2018 Mar 20;57(11):1748-1757. doi: 10.1021/acs.biochem.7b01193. Epub 2018 Mar 7.


HM2-phage resistant solventogenic Clostridium saccharoperbutylacetonicum N1-4 shows increased exopolysaccharide production.

Liu X, Turchi B, Mok KC, Taga ME, Miller MJ.

FEMS Microbiol Lett. 2017 Oct 16;364(19). doi: 10.1093/femsle/fnx191.


Decoding molecular interactions in microbial communities.

Abreu NA, Taga ME.

FEMS Microbiol Rev. 2016 Sep;40(5):648-63. doi: 10.1093/femsre/fuw019. Epub 2016 Jul 13. Review.


Sinorhizobium fredii HH103 bacteroids are not terminally differentiated and show altered O-antigen in nodules of the Inverted Repeat-Lacking Clade legume Glycyrrhiza uralensis.

Crespo-Rivas JC, Guefrachi I, Mok KC, Villaécija-Aguilar JA, Acosta-Jurado S, Pierre O, Ruiz-Sainz JE, Taga ME, Mergaert P, Vinardell JM.

Environ Microbiol. 2016 Sep;18(8):2392-404. doi: 10.1111/1462-2920.13101. Epub 2015 Dec 21.


Anaerobic biosynthesis of the lower ligand of vitamin B12.

Hazra AB, Han AW, Mehta AP, Mok KC, Osadchiy V, Begley TP, Taga ME.

Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):10792-7. doi: 10.1073/pnas.1509132112. Epub 2015 Aug 5.


Anaerobic 5-Hydroxybenzimidazole Formation from Aminoimidazole Ribotide: An Unanticipated Intersection of Thiamin and Vitamin B₁₂ Biosynthesis.

Mehta AP, Abdelwahed SH, Fenwick MK, Hazra AB, Taga ME, Zhang Y, Ealick SE, Begley TP.

J Am Chem Soc. 2015 Aug 26;137(33):10444-7. doi: 10.1021/jacs.5b03576. Epub 2015 Aug 13.


Vitamin B12 as a modulator of gut microbial ecology.

Degnan PH, Taga ME, Goodman AL.

Cell Metab. 2014 Nov 4;20(5):769-778. doi: 10.1016/j.cmet.2014.10.002. Epub 2014 Nov 4. Review.


A bioassay for the detection of benzimidazoles reveals their presence in a range of environmental samples.

Crofts TS, Men Y, Alvarez-Cohen L, Taga ME.

Front Microbiol. 2014 Nov 13;5:592. doi: 10.3389/fmicb.2014.00592. eCollection 2014.


Regiospecific formation of cobamide isomers is directed by CobT.

Crofts TS, Hazra AB, Tran JL, Sokolovskaya OM, Osadchiy V, Ad O, Pelton J, Bauer S, Taga ME.

Biochemistry. 2014 Dec 16;53(49):7805-15. doi: 10.1021/bi501147d. Epub 2014 Dec 5.


Nutrient cross-feeding in the microbial world.

Seth EC, Taga ME.

Front Microbiol. 2014 Jul 8;5:350. doi: 10.3389/fmicb.2014.00350. eCollection 2014. Review.


Identification of specific corrinoids reveals corrinoid modification in dechlorinating microbial communities.

Men Y, Seth EC, Yi S, Crofts TS, Allen RH, Taga ME, Alvarez-Cohen L.

Environ Microbiol. 2015 Dec;17(12):4873-84. doi: 10.1111/1462-2920.12500. Epub 2014 Jun 2.


Sustainable growth of Dehalococcoides mccartyi 195 by corrinoid salvaging and remodeling in defined lactate-fermenting consortia.

Men Y, Seth EC, Yi S, Allen RH, Taga ME, Alvarez-Cohen L.

Appl Environ Microbiol. 2014 Apr;80(7):2133-41. doi: 10.1128/AEM.03477-13. Epub 2014 Jan 24.


Human gut microbes use multiple transporters to distinguish vitamin B₁₂ analogs and compete in the gut.

Degnan PH, Barry NA, Mok KC, Taga ME, Goodman AL.

Cell Host Microbe. 2014 Jan 15;15(1):47-57. doi: 10.1016/j.chom.2013.12.007.


Cobamide structure depends on both lower ligand availability and CobT substrate specificity.

Crofts TS, Seth EC, Hazra AB, Taga ME.

Chem Biol. 2013 Oct 24;20(10):1265-74. doi: 10.1016/j.chembiol.2013.08.006. Epub 2013 Sep 19.


Analysis of substrate specificity in CobT homologs reveals widespread preference for DMB, the lower axial ligand of vitamin B(12).

Hazra AB, Tran JL, Crofts TS, Taga ME.

Chem Biol. 2013 Oct 24;20(10):1275-85. doi: 10.1016/j.chembiol.2013.08.007. Epub 2013 Sep 19.


Growth inhibition of Sporomusa ovata by incorporation of benzimidazole bases into cobamides.

Mok KC, Taga ME.

J Bacteriol. 2013 May;195(9):1902-11. doi: 10.1128/JB.01282-12. Epub 2013 Feb 15.


Versatility in corrinoid salvaging and remodeling pathways supports corrinoid-dependent metabolism in Dehalococcoides mccartyi.

Yi S, Seth EC, Men YJ, Stabler SP, Allen RH, Alvarez-Cohen L, Taga ME.

Appl Environ Microbiol. 2012 Nov;78(21):7745-52. doi: 10.1128/AEM.02150-12. Epub 2012 Aug 24.


Active site residues critical for flavin binding and 5,6-dimethylbenzimidazole biosynthesis in the flavin destructase enzyme BluB.

Yu TY, Mok KC, Kennedy KJ, Valton J, Anderson KS, Walker GC, Taga ME.

Protein Sci. 2012 Jun;21(6):839-49. doi: 10.1002/pro.2068. Epub 2012 Apr 23.


Methods for analysis of bacterial autoinducer-2 production.

Taga ME, Xavier KB.

Curr Protoc Microbiol. 2011 Nov;Chapter 1:Unit1C.1. doi: 10.1002/9780471729259.mc01c01s23.


Sinorhizobium meliloti requires a cobalamin-dependent ribonucleotide reductase for symbiosis with its plant host.

Taga ME, Walker GC.

Mol Plant Microbe Interact. 2010 Dec;23(12):1643-54. doi: 10.1094/MPMI-07-10-0151.


Sinorhizobium meliloti, a bacterium lacking the autoinducer-2 (AI-2) synthase, responds to AI-2 supplied by other bacteria.

Pereira CS, McAuley JR, Taga ME, Xavier KB, Miller ST.

Mol Microbiol. 2008 Dec;70(5):1223-35. doi: 10.1111/j.1365-2958.2008.06477.x.


Methods for analysis of bacterial autoinducer-2 production.

Taga ME.

Curr Protoc Microbiol. 2005 Jul;Chapter 1:Unit 1C.1. doi: 10.1002/9780471729259.mc01c01s00.


Pseudo-B12 joins the cofactor family.

Taga ME, Walker GC.

J Bacteriol. 2008 Feb;190(4):1157-9. Epub 2007 Dec 14. No abstract available.


How rhizobial symbionts invade plants: the Sinorhizobium-Medicago model.

Jones KM, Kobayashi H, Davies BW, Taga ME, Walker GC.

Nat Rev Microbiol. 2007 Aug;5(8):619-33. Review.


BluB cannibalizes flavin to form the lower ligand of vitamin B12.

Taga ME, Larsen NA, Howard-Jones AR, Walsh CT, Walker GC.

Nature. 2007 Mar 22;446(7134):449-53.


Bacterial signal destruction.

Taga ME.

ACS Chem Biol. 2007 Feb 20;2(2):89-92. Review.


Sinorhizobium meliloti bluB is necessary for production of 5,6-dimethylbenzimidazole, the lower ligand of B12.

Campbell GR, Taga ME, Mistry K, Lloret J, Anderson PJ, Roth JR, Walker GC.

Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4634-9. Epub 2006 Mar 1.


Salmonella typhimurium recognizes a chemically distinct form of the bacterial quorum-sensing signal AI-2.

Miller ST, Xavier KB, Campagna SR, Taga ME, Semmelhack MF, Bassler BL, Hughson FM.

Mol Cell. 2004 Sep 10;15(5):677-87.


Lsr-mediated transport and processing of AI-2 in Salmonella typhimurium.

Taga ME, Miller ST, Bassler BL.

Mol Microbiol. 2003 Nov;50(4):1411-27.


Chemical communication among bacteria.

Taga ME, Bassler BL.

Proc Natl Acad Sci U S A. 2003 Nov 25;100 Suppl 2:14549-54. Epub 2003 Aug 29.


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