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Items: 21


Visualization and Quantification of Phagocytosis by Neutrophils.

Guzman G, Tafesse FG.

Methods Mol Biol. 2020;2087:141-148. doi: 10.1007/978-1-0716-0154-9_11.


Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis.

Bryson BD, Rosebrock TR, Tafesse FG, Itoh CY, Nibasumba A, Babunovic GH, Corleis B, Martin C, Keegan C, Andrade P, Realegeno S, Kwon D, Modlin RL, Fortune SM.

Nat Commun. 2019 May 27;10(1):2329. doi: 10.1038/s41467-019-10065-8.


Ceramides bind VDAC2 to trigger mitochondrial apoptosis.

Dadsena S, Bockelmann S, Mina JGM, Hassan DG, Korneev S, Razzera G, Jahn H, Niekamp P, Müller D, Schneider M, Tafesse FG, Marrink SJ, Melo MN, Holthuis JCM.

Nat Commun. 2019 Apr 23;10(1):1832. doi: 10.1038/s41467-019-09654-4.


Lipids and pathogenic flaviviruses: An intimate union.

Leier HC, Messer WB, Tafesse FG.

PLoS Pathog. 2018 May 10;14(5):e1006952. doi: 10.1371/journal.ppat.1006952. eCollection 2018 May. No abstract available.


The activity of myeloid cell-specific VHH immunotoxins is target-, epitope-, subset- and organ dependent.

Bachran C, Schröder M, Conrad L, Cragnolini JJ, Tafesse FG, Helming L, Ploegh HL, Swee LK.

Sci Rep. 2017 Dec 20;7(1):17916. doi: 10.1038/s41598-017-17948-0.


Ceramide phosphoethanolamine synthase SMSr is a target of caspase-6 during apoptotic cell death.

Cabukusta B, Nettebrock NT, Kol M, Hilderink A, Tafesse FG, Holthuis JCM.

Biosci Rep. 2017 Jul 16;37(4). pii: BSR20170867. doi: 10.1042/BSR20170867. Print 2017 Aug 31.


Switching head group selectivity in mammalian sphingolipid biosynthesis by active-site-engineering of sphingomyelin synthases.

Kol M, Panatala R, Nordmann M, Swart L, van Suijlekom L, Cabukusta B, Hilderink A, Grabietz T, Mina JGM, Somerharju P, Korneev S, Tafesse FG, Holthuis JCM.

J Lipid Res. 2017 May;58(5):962-973. doi: 10.1194/jlr.M076133. Epub 2017 Mar 23.


Visualizing the Early Stages of Phagocytosis.

Rashidfarrokhi A, Richina V, Tafesse FG.

J Vis Exp. 2017 Feb 3;(120). doi: 10.3791/54646.


Switching head group selectivity in mammalian sphingolipid biosynthesis by active-site engineering of sphingomyelin synthases.

Kol M, Panatala R, Nordmann M, Swart L, van Suijlekom L, Cabukusta B, Hilderink A, Grabietz T, Mina JG, Somerharju P, Korneev S, Tafesse FG, Holthuis JC.

J Lipid Res. 2016 Jul;57(7):1273-85. doi: 10.1194/jlr.M068692. Epub 2016 May 10. Retraction in: J Lipid Res. 2017 Apr;58(4):821.


Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling.

Jahan AS, Lestra M, Swee LK, Fan Y, Lamers MM, Tafesse FG, Theile CS, Spooner E, Bruzzone R, Ploegh HL, Sanyal S.

Proc Natl Acad Sci U S A. 2016 Feb 9;113(6):E705-14. doi: 10.1073/pnas.1521763113. Epub 2016 Jan 25.


Disruption of Sphingolipid Biosynthesis Blocks Phagocytosis of Candida albicans.

Tafesse FG, Rashidfarrokhi A, Schmidt FI, Freinkman E, Dougan S, Dougan M, Esteban A, Maruyama T, Strijbis K, Ploegh HL.

PLoS Pathog. 2015 Oct 2;11(10):e1005188. doi: 10.1371/journal.ppat.1005188. eCollection 2015 Oct.


Quantitative Analysis of Cellular Diacylglycerol Content.

Tafesse FG, Strijbis K, Ploegh HL.

Bio Protoc. 2014 Aug 5;4(15). pii: e1202. doi: 10.21769/BioProtoc.1202.


GPR107, a G-protein-coupled receptor essential for intoxication by Pseudomonas aeruginosa exotoxin A, localizes to the Golgi and is cleaved by furin.

Tafesse FG, Guimaraes CP, Maruyama T, Carette JE, Lory S, Brummelkamp TR, Ploegh HL.

J Biol Chem. 2014 Aug 29;289(35):24005-18. doi: 10.1074/jbc.M114.589275. Epub 2014 Jul 16.


Sphingomyelin synthase-related protein SMSr is a suppressor of ceramide-induced mitochondrial apoptosis.

Tafesse FG, Vacaru AM, Bosma EF, Hermansson M, Jain A, Hilderink A, Somerharju P, Holthuis JC.

J Cell Sci. 2014 Jan 15;127(Pt 2):445-54. doi: 10.1242/jcs.138933. Epub 2013 Nov 20.


Bruton's Tyrosine Kinase (BTK) and Vav1 contribute to Dectin1-dependent phagocytosis of Candida albicans in macrophages.

Strijbis K, Tafesse FG, Fairn GD, Witte MD, Dougan SK, Watson N, Spooner E, Esteban A, Vyas VK, Fink GR, Grinstein S, Ploegh HL.

PLoS Pathog. 2013;9(6):e1003446. doi: 10.1371/journal.ppat.1003446. Epub 2013 Jun 27.


Intact sphingomyelin biosynthetic pathway is essential for intracellular transport of influenza virus glycoproteins.

Tafesse FG, Sanyal S, Ashour J, Guimaraes CP, Hermansson M, Somerharju P, Ploegh HL.

Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6406-11. doi: 10.1073/pnas.1219909110. Epub 2013 Apr 1.


Cell biology: A brake on lipid synthesis.

Tafesse FG, Holthuis JC.

Nature. 2010 Feb 25;463(7284):1028-9. doi: 10.1038/4631028a. No abstract available.


Roles of Arabidopsis patatin-related phospholipases a in root development are related to auxin responses and phosphate deficiency.

Rietz S, Dermendjiev G, Oppermann E, Tafesse FG, Effendi Y, Holk A, Parker JE, Teige M, Scherer GF.

Mol Plant. 2010 May;3(3):524-38. doi: 10.1093/mp/ssp109. Epub 2010 Jan 6.


Sphingomyelin synthase-related protein SMSr controls ceramide homeostasis in the ER.

Vacaru AM, Tafesse FG, Ternes P, Kondylis V, Hermansson M, Brouwers JF, Somerharju P, Rabouille C, Holthuis JC.

J Cell Biol. 2009 Jun 15;185(6):1013-27. doi: 10.1083/jcb.200903152. Epub 2009 Jun 8.


Both sphingomyelin synthases SMS1 and SMS2 are required for sphingomyelin homeostasis and growth in human HeLa cells.

Tafesse FG, Huitema K, Hermansson M, van der Poel S, van den Dikkenberg J, Uphoff A, Somerharju P, Holthuis JC.

J Biol Chem. 2007 Jun 15;282(24):17537-47. Epub 2007 Apr 22.


The multigenic sphingomyelin synthase family.

Tafesse FG, Ternes P, Holthuis JC.

J Biol Chem. 2006 Oct 6;281(40):29421-5. Epub 2006 Aug 11. Review. No abstract available.

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