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Impact of a publicly funded herpes zoster immunization program on the burden of disease in Ontario, Canada: a population-based study.

Martins D, McCormack D, Tadrous M, Gomes T, Kwong JC, Mamdani MM, Buchan SA, Antoniou T.

Clin Infect Dis. 2020 Jan 10. pii: ciaa014. doi: 10.1093/cid/ciaa014. [Epub ahead of print]


Developing a framework to incorporate real-world evidence in cancer drug funding decisions: the Canadian Real-world Evidence for Value of Cancer Drugs (CanREValue) collaboration.

Chan K, Nam S, Evans B, deOliveira C, Chambers A, Gavura S, Hoch J, Mercer RE, Dai WF, Beca J, Tadrous M, Isaranuwatchai W.

BMJ Open. 2020 Jan 7;10(1):e032884. doi: 10.1136/bmjopen-2019-032884.


Topical Corticosteroids and Type 2 Diabetes Mellitus: A Critical Appraisal.

Wong L, Tadrous M.

Br J Dermatol. 2019 Dec 28. doi: 10.1111/bjd.18853. [Epub ahead of print]


Assessing the impact of an opioid prescribing guideline for dentists in Ontario, Canada.

Guan Q, Campbell T, Martins D, Tadrous M, Juurlink D, Paterson JM, Mamdani M, Mock D, Gomes T.

J Am Dent Assoc. 2020 Jan;151(1):43-50. doi: 10.1016/j.adaj.2019.08.021. Epub 2019 Dec 5.


Comprehensive Drug-Class Review Framework for improved evidence-based drug policy and formulary modernization.

Tadrous M, Knowles S, Ruddock B, Oh P, Mamdani MM, Juurlink DN, Gomes T.

Int J Technol Assess Health Care. 2019 Dec 3:1-8. doi: 10.1017/S0266462319000746. [Epub ahead of print]


Further Evidence to Monitor Long-term Proton Pump Inhibitor Use.

Hayes KN, Nakhla NR, Tadrous M.

JAMA Netw Open. 2019 Nov 1;2(11):e1916184. doi: 10.1001/jamanetworkopen.2019.16184. No abstract available.


The uptake of the pharmacy-dispensed naloxone kit program in Ontario: A population-based study.

Choremis B, Campbell T, Tadrous M, Martins D, Antoniou T, Gomes T.

PLoS One. 2019 Oct 18;14(10):e0223589. doi: 10.1371/journal.pone.0223589. eCollection 2019.


Association Between Angiotensin-Converting Enzyme Inhibitors, Angiotensin Receptor Blockers, and Suicide.

Mamdani M, Gomes T, Greaves S, Manji S, Juurlink DN, Tadrous M, Kennedy SH, Antoniou T.

JAMA Netw Open. 2019 Oct 2;2(10):e1913304. doi: 10.1001/jamanetworkopen.2019.13304.


Time trends in opioid prescribing among Ontario long-term care residents: a repeated cross-sectional study.

Iaboni A, Campitelli MA, Bronskill SE, Diong C, Kumar M, Maclagan LC, Gomes T, Tadrous M, Maxwell CJ.

CMAJ Open. 2019 Sep 23;7(3):E582-E589. doi: 10.9778/cmajo.20190052. Print 2019 Jul-Sep.


Antiviral treatment for treatment-naïve chronic hepatitis B: systematic review and network meta-analysis of randomized controlled trials.

Wong WWL, Pechivanoglou P, Wong J, Bielecki JM, Haines A, Erman A, Saeed Y, Phoon A, Tadrous M, Younis M, Rayad NZ, Rac V, Janssen HLA, Krahn MD.

Syst Rev. 2019 Aug 19;8(1):207. doi: 10.1186/s13643-019-1126-1.


Antipsychotic initiation among adults with intellectual and developmental disabilities in Ontario: a population-based cohort study.

Gomes T, Khuu W, Tadrous M, Vigod S, Cobigo V, Lunsky Y.

BMJ Open. 2019 Jul 30;9(7):e028125. doi: 10.1136/bmjopen-2018-028125.


Association of Mirabegron With the Risk of Arrhythmia in Adult Patients 66 Years or Older-A Population-Based Cohort Study.

Tadrous M, Matta R, Greaves S, Herschorn S, Mamdani MM, Juurlink DN, Gomes T.

JAMA Intern Med. 2019 Jul 15. doi: 10.1001/jamainternmed.2019.2011. [Epub ahead of print] No abstract available.


National trends in prescription drug expenditures and projections for 2019.

Schumock GT, Stubbings J, Hoffman JM, Wiest MD, Suda KJ, Rim MH, Tadrous M, Tichy EM, Cuellar S, Clark JS, Matusiak LM, Hunkler RJ, Vermeulen LC.

Am J Health Syst Pharm. 2019 Jul 18;76(15):1105-1121. doi: 10.1093/ajhp/zxz109.


Quality of primary care among individuals receiving treatment for opioid use disorder.

Spithoff S, Kiran T, Khuu W, Kahan M, Guan Q, Tadrous M, Leece P, Martins D, Gomes T.

Can Fam Physician. 2019 May;65(5):343-351.


Confinement-Induced Transition between Wavelike Collective Cell Migration Modes.

Petrolli V, Le Goff M, Tadrous M, Martens K, Allier C, Mandula O, Hervé L, Henkes S, Sknepnek R, Boudou T, Cappello G, Balland M.

Phys Rev Lett. 2019 Apr 26;122(16):168101. doi: 10.1103/PhysRevLett.122.168101.


Variability in the validity and reliability of outcome measures identified in a systematic review to assess treatment efficacy of cognitive enhancers for Alzheimer's Dementia.

Soobiah C, Tadrous M, Knowles S, Blondal E, Ashoor HM, Ghassemi M, Khan PA, Ho J, Tricco AC, Straus SE.

PLoS One. 2019 Apr 18;14(4):e0215225. doi: 10.1371/journal.pone.0215225. eCollection 2019.


Impact of delisting high-strength opioid formulations from a public drug benefit formulary on opioid utilization in Ontario, Canada.

Martins D, Khuu W, Tadrous M, Juurlink DN, Mamdani MM, Paterson JM, Gomes T; Ontario Drug Policy Research Network.

Pharmacoepidemiol Drug Saf. 2019 May;28(5):726-733. doi: 10.1002/pds.4764. Epub 2019 Mar 14.


Evaluation of the fentanyl patch-for-patch program in Ontario, Canada.

Tadrous M, Greaves S, Martins D, Nadeem K, Singh S, Mamdani MM, Juurlink DN, Gomes T.

Int J Drug Policy. 2019 Apr;66:82-86. doi: 10.1016/j.drugpo.2019.01.025. Epub 2019 Feb 8.


"Like being put on an ice floe and shoved away": A qualitative study of the impacts of opioid-related policy changes on people who take opioids.

Antoniou T, Ala-Leppilampi K, Shearer D, Parsons JA, Tadrous M, Gomes T.

Int J Drug Policy. 2019 Apr;66:15-22. doi: 10.1016/j.drugpo.2019.01.015. Epub 2019 Jan 24.


The Burden of Opioid-Related Mortality in the United States.

Gomes T, Tadrous M, Mamdani MM, Paterson JM, Juurlink DN.

JAMA Netw Open. 2018 Jun 1;1(2):e180217. doi: 10.1001/jamanetworkopen.2018.0217.


Analysis of Trends in Insulin Utilization and Spending Across Canada From 2010 to 2015.

Xu Y, Gomes T, Mamdani MM, Juurlink DN, Cadarette SM, Tadrous M.

Can J Diabetes. 2019 Apr;43(3):179-185.e1. doi: 10.1016/j.jcjd.2018.08.190. Epub 2018 Aug 16.


Interprovincial Variation of Psychotropic Prescriptions Dispensed to Older Canadian Adults.

Black CD, McCarthy L, Gomes T, Mamdani M, Juurlink D, Tadrous M.

Can Geriatr J. 2018 Sep 30;21(3):269-273. doi: 10.5770/cgj.21.307. eCollection 2018 Sep.


Trends in the utilisation of COPD therapeutic regimens before and after the introduction of LAMA/LABA combination products: A population-based study.

Parkin L, Khuu W, Stanbrook MB, Tadrous M, Martins D, Gomes T.

Respir Med. 2018 Oct;143:1-7. doi: 10.1016/j.rmed.2018.08.001. Epub 2018 Aug 14.


Contributions of prescribed and non-prescribed opioids to opioid related deaths: population based cohort study in Ontario, Canada.

Gomes T, Khuu W, Martins D, Tadrous M, Mamdani MM, Paterson JM, Juurlink DN.

BMJ. 2018 Aug 29;362:k3207. doi: 10.1136/bmj.k3207.


Opioids in Ontario: the current state of affairs and a path forward.

Tadrous M.

Expert Rev Clin Pharmacol. 2018 Oct;11(10):927-929. doi: 10.1080/17512433.2018.1516142. Epub 2018 Aug 30. No abstract available.


Comparing the contribution of prescribed opioids to opioid-related hospitalizations across Canada: A multi-jurisdictional cross-sectional study.

Gomes T, Khuu W, Craiovan D, Martins D, Hunt J, Lee K, Tadrous M, Mamdani MM, Paterson JM, Juurlink DN.

Drug Alcohol Depend. 2018 Oct 1;191:86-90. doi: 10.1016/j.drugalcdep.2018.06.028. Epub 2018 Jul 31.


History and publication trends in the diffusion and early uptake of indirect comparison meta-analytic methods to study drugs: animated coauthorship networks over time.

Ban JK, Tadrous M, Lu AX, Cicinelli EA, Cadarette SM.

BMJ Open. 2018 Jun 30;8(6):e019110. doi: 10.1136/bmjopen-2017-019110.


Evaluating the early impacts of delisting high-strength opioids on patterns of prescribing in Ontario.

Guan Q, Khuu W, Martins D, Tadrous M, Chiu M, Do MT, Gomes T.

Health Promot Chronic Dis Prev Can. 2018 Jun;38(6):256-262. doi: 10.24095/hpcdp.38.6.07. English, French.


Fixed-dose combination antihypertensive medications, adherence, and clinical outcomes: A population-based retrospective cohort study.

Verma AA, Khuu W, Tadrous M, Gomes T, Mamdani MM.

PLoS Med. 2018 Jun 11;15(6):e1002584. doi: 10.1371/journal.pmed.1002584. eCollection 2018 Jun.


A population-based study of the risk of osteoporosis and fracture with dutasteride and finasteride.

Antoniou T, Macdonald EM, Yao Z, Gomes T, Tadrous M, Ho JM, Mamdani MM, Juurlink DN; Canadian Drug Safety and Effectiveness Research Network.

BMC Musculoskelet Disord. 2018 May 22;19(1):160. doi: 10.1186/s12891-018-2076-9.


Network meta-analysis: an introduction for pharmacists.

Xu Y, Amiche MA, Tadrous M.

Int J Clin Pharm. 2018 Oct;40(5):942-947. doi: 10.1007/s11096-018-0656-2. Review.


Clinical indications associated with opioid initiation for pain management in Ontario, Canada: a population-based cohort study.

Pasricha SV, Tadrous M, Khuu W, Juurlink DN, Mamdani MM, Paterson JM, Gomes T.

Pain. 2018 Aug;159(8):1562-1568. doi: 10.1097/j.pain.0000000000001242.


Measuring the Burden of Opioid-related Mortality in Ontario, Canada.

Gomes T, Greaves S, Tadrous M, Mamdani MM, Paterson JM, Juurlink DN.

J Addict Med. 2018 Sep/Oct;12(5):418-419. doi: 10.1097/ADM.0000000000000412. No abstract available.


Publicly Funded Oral Chronic Hepatitis B Treatment Patterns in Ontario over 16 Years: An Ecologic Study.

Tadrous M, Brahmania M, Martins D, Knowles S, Janssen HLA, Mamdani MM, Juurlink DN, Gomes T.

J Manag Care Spec Pharm. 2018 May;24(5):464-468. doi: 10.18553/jmcp.2018.24.5.464.


Trends in the use of older overactive bladder agents and uptake of fesoterodine and mirabegron in Canada.

Minhas R, Tadrous M, Elterman D, Gomes T.

Neurourol Urodyn. 2018 Jun;37(5):1693-1700. doi: 10.1002/nau.23469. Epub 2018 Apr 23.


Catastrophic drug coverage: utilization insights from the Ontario Trillium Drug Program.

Tadrous M, Greaves S, Martins D, Mamdani MM, Juurlink DN, Gomes T.

CMAJ Open. 2018 Mar 14;6(1):E132-E138. doi: 10.9778/cmajo.20170132.


Opioid prescribing and adverse events in opioid-naive patients treated by emergency physicians versus family physicians: a population-based cohort study.

Borgundvaag B, McLeod S, Khuu W, Varner C, Tadrous M, Gomes T.

CMAJ Open. 2018 Mar 1;6(1):E110-E117. doi: 10.9778/cmajo.20170151.


Publicly funded overactive bladder drug treatment patterns in Ontario over 15 years: An ecological study.

Tadrous M, Elterman D, Khuu W, Mamdani MM, Juurlink DN, Gomes T.

Can Urol Assoc J. 2018 Mar;12(3):E142-E145. doi: 10.5489/cuaj.4541. Epub 2017 Dec 22.


Prior Authorization and Canadian Public Utilization of Direct-Acting Oral Anticoagulants.

Gao L, Tadrous M, Knowles S, Mamdani M, Paterson JM, Juurlink D, Gomes T.

Healthc Policy. 2017 Nov;13(2):68-78.


Real-world health care utilization and effectiveness of omalizumab for the treatment of severe asthma.

Tadrous M, Khuu W, Lebovic G, Stanbrook MB, Martins D, Paterson JM, Mamdani MM, Juurlink DN, Gomes T.

Ann Allergy Asthma Immunol. 2018 Jan;120(1):59-65.e2. doi: 10.1016/j.anai.2017.08.016. Epub 2017 Oct 3.


Antipsychotic Use With and Without Comorbid Psychiatric Diagnosis Among Adults with Intellectual and Developmental Disabilities.

Lunsky Y, Khuu W, Tadrous M, Vigod S, Cobigo V, Gomes T.

Can J Psychiatry. 2018 Jun;63(6):361-369. doi: 10.1177/0706743717727240. Epub 2017 Aug 22.


Patterns of physician prescribing for opioid maintenance treatment in Ontario, Canada in 2014.

Guan Q, Khuu W, Spithoff S, Kiran T, Kahan M, Tadrous M, Martins D, Leece P, Gomes T.

Drug Alcohol Depend. 2017 Aug 1;177:315-321. doi: 10.1016/j.drugalcdep.2017.05.002. Epub 2017 Jul 19.


Impact of Unrestricted Access to Pregabalin on the Use of Opioids and Other CNS-Active Medications: A Cross-Sectional Time Series Analysis.

Kwok H, Khuu W, Fernandes K, Martins D, Tadrous M, Singh S, Juurlink DN, Gomes T.

Pain Med. 2017 Jun 1;18(6):1019-1026. doi: 10.1093/pm/pnw351.


Association between statin use and ischemic stroke or major hemorrhage in patients taking dabigatran for atrial fibrillation.

Antoniou T, Macdonald EM, Yao Z, Hollands S, Gomes T, Tadrous M, Mamdani MM, Juurlink DN; Canadian Drug Safety and Effectiveness Research Network.

CMAJ. 2017 Jan 9;189(1):E4-E10. doi: 10.1503/cmaj.160303. Epub 2016 Nov 21.


Diffusion of Innovations model helps interpret the comparative uptake of two methodological innovations: co-authorship network analysis and recommendations for the integration of novel methods in practice.

Cadarette SM, Ban JK, Consiglio GP, Black CD, Dubins D, Marin A, Tadrous M.

J Clin Epidemiol. 2017 Apr;84:150-160. doi: 10.1016/j.jclinepi.2016.12.006. Epub 2016 Dec 23.


Association of a Blood Glucose Test Strip Quantity-Limit Policy With Patient Outcomes: A Population-Based Study.

Gomes T, Martins D, Tadrous M, Paterson JM, Shah BR, Tu JV, Juurlink DN, Chu A, Mamdani MM.

JAMA Intern Med. 2017 Jan 1;177(1):61-66. doi: 10.1001/jamainternmed.2016.6851. Erratum in: JAMA Intern Med. 2017 Aug 1;177(8):1228.


Varenicline and Risk of Self-Harm: A Nested Case-Control Study.

Tadrous M, Martins D, Yao Z, Mamdani MM, Juurlink DN, Gomes T, Antoniou T.

PLoS One. 2016 Sep 23;11(9):e0163681. doi: 10.1371/journal.pone.0163681. eCollection 2016.


The appropriateness and persistence of testosterone replacement therapy in Ontario.

Martins D, Yao Z, Tadrous M, Shah BR, Juurlink DN, Mamdani MM, Gomes T; Ontario Drug Policy Research Network.

Pharmacoepidemiol Drug Saf. 2017 Feb;26(2):119-126. doi: 10.1002/pds.4083. Epub 2016 Aug 16.


Persistence of Antipsychotic Treatment in Elderly Dementia Patients: A Retrospective, Population-Based Cohort Study.

Mast G, Fernandes K, Tadrous M, Martins D, Herrmann N, Gomes T.

Drugs Real World Outcomes. 2016 May 13;3(2):175-182. eCollection 2016 Jun.


Interprovincial Variation in Antipsychotic and Antidepressant Prescriptions Dispensed in the Canadian Pediatric Population.

Arora N, Knowles S, Gomes T, Mamdani MM, Juurlink DN, Carlisle C, Tadrous M.

Can J Psychiatry. 2016 Dec;61(12):758-765. doi: 10.1177/0706743716649190. Epub 2016 Jul 10.

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