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Rates and Correlates of Short Term Virologic Response among Treatment-Naïve HIV-Infected Children Initiating Antiretroviral Therapy in Ethiopia: A Multi-Center Prospective Cohort Study.

Tadesse BT, Chala A, Mukonzo J, Chaka TE, Tadesse S, Makonnen E, Brumme ZL, Brumme CJ, Aklillu E.

Pathogens. 2019 Sep 24;8(4). pii: E161. doi: 10.3390/pathogens8040161.


Prevalence and Correlates of Pre-Treatment HIV Drug Resistance among HIV-Infected Children in Ethiopia.

Tadesse BT, Tsai O, Chala A, Chaka TE, Eromo T, Lapointe HR, Baraki B, Shahid A, Tadesse S, Makonnen E, Brumme ZL, Aklillu E, Brumme CJ.

Viruses. 2019 Sep 19;11(9). pii: E877. doi: 10.3390/v11090877.


Bioavailability and cytosolic kinases modulate response to deoxynucleoside therapy in TK2 deficiency.

Lopez-Gomez C, Hewan H, Sierra C, Akman HO, Sanchez-Quintero MJ, Juanola-Falgarona M, Tadesse S, Tanji K, Konofagou EE, Hirano M.

EBioMedicine. 2019 Aug;46:356-367. doi: 10.1016/j.ebiom.2019.07.037. Epub 2019 Aug 2.


Synthesis and evaluation of 2'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine]-1',5'-dione derivatives as Mnk inhibitors.

Abdelaziz AM, Basnet SKC, Islam S, Li M, Tadesse S, Albrecht H, Gerber C, Yu M, Wang S.

Bioorg Med Chem Lett. 2019 Sep 15;29(18):2650-2654. doi: 10.1016/j.bmcl.2019.07.043. Epub 2019 Jul 23.


Discovery of CDK5 Inhibitors through Structure-Guided Approach.

Khair NZ, Lenjisa JL, Tadesse S, Kumarasiri M, Basnet SKC, Mekonnen LB, Li M, Diab S, Sykes MJ, Albrecht H, Milne R, Wang S.

ACS Med Chem Lett. 2019 Mar 20;10(5):786-791. doi: 10.1021/acsmedchemlett.9b00029. eCollection 2019 May 9.


HIV and cART-Associated Dyslipidemia Among HIV-Infected Children.

Tadesse BT, Foster BA, Chala A, Chaka TE, Bizuayehu T, Ayalew F, H/Meskel G, Tadesse S, Jerene D, Makonnen E, Aklillu E.

J Clin Med. 2019 Mar 28;8(4). pii: E430. doi: 10.3390/jcm8040430.


Prevalence of Anemia and Associated Factors Among Hospitalized Children Attending the University of Gondar Hospital, Northwest Ethiopia.

Enawgaw B, Workineh Y, Tadesse S, Mekuria E, Addisu A, Genetu M.

EJIFCC. 2019 Mar 1;30(1):35-47. eCollection 2019 Mar.


Cyclin-Dependent Kinase 2 Inhibitors in Cancer Therapy: An Update.

Tadesse S, Caldon EC, Tilley W, Wang S.

J Med Chem. 2019 May 9;62(9):4233-4251. doi: 10.1021/acs.jmedchem.8b01469. Epub 2018 Dec 20.


Correction to: Prevalence, antimicrobial susceptibility profile and predictors of asymptomatic bacteriuria among pregnant women in Adigrat General Hospital, Northern Ethiopia.

Tadesse S, Kahsay T, Adhanom G, Kahsu G, Legese H, G/Wahid A, Derbie A.

BMC Res Notes. 2018 Nov 8;11(1):798. doi: 10.1186/s13104-018-3911-7.


Prevalence, antimicrobial susceptibility profile and predictors of asymptomatic bacteriuria among pregnant women in Adigrat General Hospital, Northern Ethiopia.

Tadesse S, Kahsay T, Adhanom G, Kahsu G, Legese H, G/Wahid A, Derbie A.

BMC Res Notes. 2018 Oct 19;11(1):740. doi: 10.1186/s13104-018-3844-1. Erratum in: BMC Res Notes. 2018 Nov 8;11(1):798.


CoQ10 supplementation rescues nephrotic syndrome through normalization of H2S oxidation pathway.

Kleiner G, Barca E, Ziosi M, Emmanuele V, Xu Y, Hidalgo-Gutierrez A, Qiao C, Tadesse S, Area-Gomez E, Lopez LC, Quinzii CM.

Biochim Biophys Acta Mol Basis Dis. 2018 Nov;1864(11):3708-3722. doi: 10.1016/j.bbadis.2018.09.002. Epub 2018 Sep 6.


Estimating the spatial risk of tuberculosis distribution in Gurage zone, southern Ethiopia: a geostatistical kriging approach.

Tadesse S, Enqueselassie F, Gebreyesus SH.

BMC Public Health. 2018 Jun 25;18(1):783. doi: 10.1186/s12889-018-5711-3.


USMG5 Ashkenazi Jewish founder mutation impairs mitochondrial complex V dimerization and ATP synthesis.

Barca E, Ganetzky RD, Potluri P, Juanola-Falgarona M, Gai X, Li D, Jalas C, Hirsch Y, Emmanuele V, Tadesse S, Ziosi M, Akman HO, Chung WK, Tanji K, McCormick EM, Place E, Consugar M, Pierce EA, Hakonarson H, Wallace DC, Hirano M, Falk MJ.

Hum Mol Genet. 2018 Oct 1;27(19):3305-3312. doi: 10.1093/hmg/ddy231.


Spatial and space-time clustering of tuberculosis in Gurage Zone, Southern Ethiopia.

Tadesse S, Enqueselassie F, Hagos S.

PLoS One. 2018 Jun 5;13(6):e0198353. doi: 10.1371/journal.pone.0198353. eCollection 2018.


Prevalence and Associated Factors of Sleep Quality among Adults in Jimma Town, Southwest Ethiopia: A Community-Based Cross-Sectional Study.

Berhanu H, Mossie A, Tadesse S, Geleta D.

Sleep Disord. 2018 Apr 22;2018:8342328. doi: 10.1155/2018/8342328. eCollection 2018.


Antimicrobial resistance profile of Staphylococcus aureus isolated from patients with infection at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia.

Tadesse S, Alemayehu H, Tenna A, Tadesse G, Tessema TS, Shibeshi W, Eguale T.

BMC Pharmacol Toxicol. 2018 May 21;19(1):24. doi: 10.1186/s40360-018-0210-9.


Non-Alcoholic Fatty Liver Disease and Associated Factors among Type 2 Diabetic Patients in Southwest Ethiopia.

Zawdie B, Tadesse S, Wolide AD, Nigatu TA, Bobasa EM.

Ethiop J Health Sci. 2018 Jan;28(1):19-30.


CDK5 in oncology: recent advances and future prospects.

Lenjisa JL, Tadesse S, Khair NZ, Kumarasiri M, Yu M, Albrecht H, Milne R, Wang S.

Future Med Chem. 2017 Oct;9(16):1939-1962. doi: 10.4155/fmc-2017-0097. Epub 2017 Oct 27. Review.


MUC2 mucin deficiency alters inflammatory and metabolic pathways in the mouse intestinal mucosa.

Tadesse S, Corner G, Dhima E, Houston M, Guha C, Augenlicht L, Velcich A.

Oncotarget. 2017 Apr 6;8(42):71456-71470. doi: 10.18632/oncotarget.16886. eCollection 2017 Sep 22.


Association of trace metal elements with lipid profiles in type 2 diabetes mellitus patients: a cross sectional study.

Wolide AD, Zawdie B, Alemayehu T, Tadesse S.

BMC Endocr Disord. 2017 Oct 13;17(1):64. doi: 10.1186/s12902-017-0217-z.


Unprecedented anticancer activities of organorhenium sulfonato and carboxylato complexes against hormone-dependent MCF-7 and hormone-independent triple-negative MDA-MB-231 breast cancer cells.

Wilder PT, Weber DJ, Winstead A, Parnell S, Hinton TV, Stevenson M, Giri D, Azemati S, Olczak P, Powell BV, Odebode T, Tadesse S, Zhang Y, Pramanik SK, Wachira JM, Ghimire S, McCarthy P, Barfield A, Banerjee HN, Chen C, Golen JA, Rheingold AL, Krause JA, Ho DM, Zavalij PY, Shaw R, Mandal SK.

Mol Cell Biochem. 2018 Apr;441(1-2):151-163. doi: 10.1007/s11010-017-3181-z. Epub 2017 Sep 14.


Discovery and pharmacological characterization of a novel series of highly selective inhibitors of cyclin-dependent kinases 4 and 6 as anticancer agents.

Tadesse S, Bantie L, Tomusange K, Yu M, Islam S, Bykovska N, Noll B, Zhu G, Li P, Lam F, Kumarasiri M, Milne R, Wang S.

Br J Pharmacol. 2018 Jun;175(12):2399-2413. doi: 10.1111/bph.13974. Epub 2018 May 8.


A novel series of N-(pyridin-2-yl)-4-(thiazol-5-yl)pyrimidin-2-amines as highly potent CDK4/6 inhibitors.

Tadesse S, Zhu G, Mekonnen LB, Lenjisa JL, Yu M, Brown MP, Wang S.

Future Med Chem. 2017 Sep;9(13):1495-1506. doi: 10.4155/fmc-2017-0076. Epub 2017 Aug 10.


Patterns of psychiatric admissions and predictors of patient's outcome in Jimma University Teaching and Referral Hospital: a retrospective study.

Tadesse S, Gizaw AT, Abraha GK, Gebretsadik LA.

Int J Ment Health Syst. 2017 Jun 14;11:41. doi: 10.1186/s13033-017-0148-0. eCollection 2017.


Deoxycytidine and Deoxythymidine Treatment for Thymidine Kinase 2 Deficiency.

Lopez-Gomez C, Levy RJ, Sanchez-Quintero MJ, Juanola-Falgarona M, Barca E, Garcia-Diaz B, Tadesse S, Garone C, Hirano M.

Ann Neurol. 2017 May;81(5):641-652. doi: 10.1002/ana.24922. Epub 2017 May 4.


Determinants of anemia among pregnant mothers attending antenatal care in Dessie town health facilities, northern central Ethiopia, unmatched case -control study.

Tadesse SE, Seid O, G/Mariam Y, Fekadu A, Wasihun Y, Endris K, Bitew A.

PLoS One. 2017 Mar 13;12(3):e0173173. doi: 10.1371/journal.pone.0173173. eCollection 2017.


Highly Potent, Selective, and Orally Bioavailable 4-Thiazol-N-(pyridin-2-yl)pyrimidin-2-amine Cyclin-Dependent Kinases 4 and 6 Inhibitors as Anticancer Drug Candidates: Design, Synthesis, and Evaluation.

Tadesse S, Yu M, Mekonnen LB, Lam F, Islam S, Tomusange K, Rahaman MH, Noll B, Basnet SK, Teo T, Albrecht H, Milne R, Wang S.

J Med Chem. 2017 Mar 9;60(5):1892-1915. doi: 10.1021/acs.jmedchem.6b01670. Epub 2017 Feb 16.


Association between thyroid hormone parameters and dyslipidemia among type 2 diabetes mellitus patients: Comparative cross-sectional study.

Wolide AD, Zawdie B, Alemayehu T, Tadesse S.

Diabetes Metab Syndr. 2017 Nov;11 Suppl 1:S257-S262. doi: 10.1016/j.dsx.2016.12.041. Epub 2016 Dec 26.


Antimalarial activity of Syzygium guineense during early and established Plasmodium infection in rodent models.

Tadesse SA, Wubneh ZB.

BMC Complement Altern Med. 2017 Jan 5;17(1):21. doi: 10.1186/s12906-016-1538-6.


Evaluation of serum ferritin and some metal elements in type 2 diabetes mellitus patients: comparative cross-sectional study.

Wolide AD, Zawdie B, Alemayehu T, Tadesse S.

Diabetes Metab Syndr Obes. 2016 Dec 2;9:417-424. eCollection 2016.


Coenzyme Q deficiency causes impairment of the sulfide oxidation pathway.

Ziosi M, Di Meo I, Kleiner G, Gao XH, Barca E, Sanchez-Quintero MJ, Tadesse S, Jiang H, Qiao C, Rodenburg RJ, Scalais E, Schuelke M, Willard B, Hatzoglou M, Tiranti V, Quinzii CM.

EMBO Mol Med. 2017 Jan;9(1):96-111. doi: 10.15252/emmm.201606356.


Dynamics of Base Excision Repair at the Maternal-Fetal Interface in Pregnancies Complicated by Preeclampsia.

Tadesse S, Norwitz NG, Guller S, Arcuri F, Toti P, Norwitz ER, Kidane D.

Reprod Sci. 2017 Jun;24(6):856-864. doi: 10.1177/1933719116670519. Epub 2016 Oct 5.


Synthesis, characterization, and evaluation of (E)-methyl 2-((2-oxonaphthalen-1(2H)-ylidene)methylamino)acetate as a biological agent and an anion sensor.

Zeyrek CT, Boyacioğlu B, Yıldız M, Ünver H, Yolal D, Demir N, Elmali A, Tadesse S, Aslan K.

Bioorg Med Chem. 2016 Nov 1;24(21):5592-5601. doi: 10.1016/j.bmc.2016.09.018. Epub 2016 Sep 13.


Decreased Coenzyme Q10 Levels in Multiple System Atrophy Cerebellum.

Barca E, Kleiner G, Tang G, Ziosi M, Tadesse S, Masliah E, Louis ED, Faust P, Kang UJ, Torres J, Cortes EP, Vonsattel JP, Kuo SH, Quinzii CM.

J Neuropathol Exp Neurol. 2016 Jul;75(7):663-72. doi: 10.1093/jnen/nlw037. Epub 2016 May 27.


Occupational injuries among building construction workers in Addis Ababa, Ethiopia.

Tadesse S, Israel D.

J Occup Med Toxicol. 2016 Apr 11;11:16. doi: 10.1186/s12995-016-0107-8. eCollection 2016.


Stigma against Tuberculosis Patients in Addis Ababa, Ethiopia.

Tadesse S.

PLoS One. 2016 Apr 7;11(4):e0152900. doi: 10.1371/journal.pone.0152900. eCollection 2016.


Awareness of occupational hazards and associated factors among welders in Lideta Sub-City, Addis Ababa, Ethiopia.

Tadesse S, Bezabih K, Destaw B, Assefa Y.

J Occup Med Toxicol. 2016 Apr 5;11:15. doi: 10.1186/s12995-016-0105-x. eCollection 2016.


A Highly Selective Sensor for Cyanide in Organic Media and on Solid Surfaces.

Barare B, Babahan I, Hijji YM, Bonyi E, Tadesse S, Aslan K.

Sensors (Basel). 2016 Feb 24;16(3):271. doi: 10.3390/s16030271.


Utilization of personal protective equipment and associated factors among textile factory workers at Hawassa Town, Southern Ethiopia.

Tadesse S, Kelaye T, Assefa Y.

J Occup Med Toxicol. 2016 Feb 19;11:6. doi: 10.1186/s12995-016-0096-7. eCollection 2016.


Discovery and Structure-Guided Optimization of Diarylmethanesulfonamide Disrupters of Glucokinase-Glucokinase Regulatory Protein (GK-GKRP) Binding: Strategic Use of a N → S (nN → σ*S-X) Interaction for Conformational Constraint.

Pennington LD, Bartberger MD, Croghan MD, Andrews KL, Ashton KS, Bourbeau MP, Chen J, Chmait S, Cupples R, Fotsch C, Helmering J, Hong FT, Hungate RW, Jordan SR, Kong K, Liu L, Michelsen K, Moyer C, Nishimura N, Norman MH, Reichelt A, Siegmund AC, Sivits G, Tadesse S, Tegley CM, Van G, Yang KC, Yao G, Zhang J, Lloyd DJ, Hale C, St Jean DJ Jr.

J Med Chem. 2015 Dec 24;58(24):9663-79. doi: 10.1021/acs.jmedchem.5b01367. Epub 2015 Dec 1.


Oxopyrido[2,3-d]pyrimidines as Covalent L858R/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors.

Wurz RP, Pettus LH, Ashton K, Brown J, Chen JJ, Herberich B, Hong FT, Hu-Harrington E, Nguyen T, St Jean DJ Jr, Tadesse S, Bauer D, Kubryk M, Zhan J, Cooke K, Mitchell P, Andrews KL, Hsieh F, Hickman D, Kalyanaraman N, Wu T, Reid DL, Lobenhofer EK, Andrews DA, Everds N, Guzman R, Parsons AT, Hedley SJ, Tedrow J, Thiel OR, Potter M, Radinsky R, Beltran PJ, Tasker AS.

ACS Med Chem Lett. 2015 Jul 27;6(9):987-92. doi: 10.1021/acsmedchemlett.5b00193. eCollection 2015 Sep 10.


Targeting CDK6 in cancer: State of the art and new insights.

Tadesse S, Yu M, Kumarasiri M, Le BT, Wang S.

Cell Cycle. 2015;14(20):3220-30. doi: 10.1080/15384101.2015.1084445. Review.


Sickness absenteeism and associated factors among horticulture employees in lume district, southeast Ethiopia.

Tadesse S, Ebrahim K, Gizaw Z.

J Occup Med Toxicol. 2015 Aug 12;10:32. doi: 10.1186/s12995-015-0074-5. eCollection 2015.


Lack of aprataxin impairs mitochondrial functions via downregulation of the APE1/NRF1/NRF2 pathway.

Garcia-Diaz B, Barca E, Balreira A, Lopez LC, Tadesse S, Krishna S, Naini A, Mariotti C, Castellotti B, Quinzii CM.

Hum Mol Genet. 2015 Aug 15;24(16):4516-29. doi: 10.1093/hmg/ddv183. Epub 2015 May 14.


Small Molecule Disruptors of the Glucokinase-Glucokinase Regulatory Protein Interaction: 5. A Novel Aryl Sulfone Series, Optimization Through Conformational Analysis.

Tamayo NA, Norman MH, Bartberger MD, Hong FT, Bo Y, Liu L, Nishimura N, Yang KC, Tadesse S, Fotsch C, Chen J, Chmait S, Cupples R, Hale C, Jordan SR, Lloyd DJ, Sivits G, Van G, St Jean DJ Jr.

J Med Chem. 2015 Jun 11;58(11):4462-82. doi: 10.1021/jm5018175. Epub 2015 Jun 1.


Sub-optical wavelength acoustic wave modulation of integrated photonic resonators at microwave frequencies.

Tadesse SA, Li M.

Nat Commun. 2014 Nov 17;5:5402. doi: 10.1038/ncomms6402.


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