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Items: 14


Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils.

Ohayon D, De Chiara A, Dang PM, Thieblemont N, Chatfield S, Marzaioli V, Burgener SS, Mocek J, Candalh C, Pintard C, Tacnet-Delorme P, Renault G, Lagoutte I, Favier M, Walker F, Hurtado-Nedelec M, Desplancq D, Weiss E, Benarafa C, Housset D, Marie JC, Frachet P, El-Benna J, Witko-Sarsat V.

J Exp Med. 2019 Sep 6. pii: jem.20180371. doi: 10.1084/jem.20180371. [Epub ahead of print]


Proteomic analysis of neutrophils in ANCA-associated vasculitis reveals a dysregulation in proteinase 3-associated proteins such as annexin-A1 involved in apoptotic cell clearance.

Everts-Graber J, Martin KR, Thieblemont N, Mocek J, Roccabianca A, Chafey P, Le Gall M, Tacnet-Delorme P, Reutelingsperger CP, Naccache JM, Bonnotte B, Karras A, Puéchal X, Guillevin L, Terrier B, Frachet P, Perretti M, Mouthon L, Witko-Sarsat V.

Kidney Int. 2019 Aug;96(2):397-408. doi: 10.1016/j.kint.2019.02.017. Epub 2019 Mar 4.


Proteinase 3 Interferes With C1q-Mediated Clearance of Apoptotic Cells.

Tacnet-Delorme P, Gabillet J, Chatfield S, Thieblemont N, Frachet P, Witko-Sarsat V.

Front Immunol. 2018 Apr 25;9:818. doi: 10.3389/fimmu.2018.00818. eCollection 2018.


Calreticulin Release at an Early Stage of Death Modulates the Clearance by Macrophages of Apoptotic Cells.

Osman R, Tacnet-Delorme P, Kleman JP, Millet A, Frachet P.

Front Immunol. 2017 Aug 23;8:1034. doi: 10.3389/fimmu.2017.01034. eCollection 2017.


Relative contribution of c1q and apoptotic cell-surface calreticulin to macrophage phagocytosis.

Verneret M, Tacnet-Delorme P, Osman R, Awad R, Grichine A, Kleman JP, Frachet P.

J Innate Immun. 2014;6(4):426-34. doi: 10.1159/000358834. Epub 2014 Feb 15.


Human and pneumococcal cell surface glyceraldehyde-3-phosphate dehydrogenase (GAPDH) proteins are both ligands of human C1q protein.

Terrasse R, Tacnet-Delorme P, Moriscot C, Pérard J, Schoehn G, Vernet T, Thielens NM, Di Guilmi AM, Frachet P.

J Biol Chem. 2012 Dec 14;287(51):42620-33. doi: 10.1074/jbc.M112.423731. Epub 2012 Oct 18.


Proteinase 3, the autoantigen in granulomatosis with polyangiitis, associates with calreticulin on apoptotic neutrophils, impairs macrophage phagocytosis, and promotes inflammation.

Gabillet J, Millet A, Pederzoli-Ribeil M, Tacnet-Delorme P, Guillevin L, Mouthon L, Frachet P, Witko-Sarsat V.

J Immunol. 2012 Sep 1;189(5):2574-83. doi: 10.4049/jimmunol.1200600. Epub 2012 Jul 27.


Investigations on the C1q-calreticulin-phosphatidylserine interactions yield new insights into apoptotic cell recognition.

Païdassi H, Tacnet-Delorme P, Verneret M, Gaboriaud C, Houen G, Duus K, Ling WL, Arlaud GJ, Frachet P.

J Mol Biol. 2011 Apr 29;408(2):277-90. doi: 10.1016/j.jmb.2011.02.029. Epub 2011 Feb 23.


How phagocytes track down and respond to apoptotic cells.

Paidassi H, Tacnet-Delorme P, Arlaud GJ, Frachet P.

Crit Rev Immunol. 2009;29(2):111-30. Review.


The lectin-like activity of human C1q and its implication in DNA and apoptotic cell recognition.

Païdassi H, Tacnet-Delorme P, Lunardi T, Arlaud GJ, Thielens NM, Frachet P.

FEBS Lett. 2008 Sep 3;582(20):3111-6. doi: 10.1016/j.febslet.2008.08.001. Epub 2008 Aug 12.


C1q binds phosphatidylserine and likely acts as a multiligand-bridging molecule in apoptotic cell recognition.

Païdassi H, Tacnet-Delorme P, Garlatti V, Darnault C, Ghebrehiwet B, Gaboriaud C, Arlaud GJ, Frachet P.

J Immunol. 2008 Feb 15;180(4):2329-38.


Interaction of C1q and mannan-binding lectin with viruses.

Thielens NM, Tacnet-Delorme P, Arlaud GJ.

Immunobiology. 2002 Sep;205(4-5):563-74. Review.


In vitro analysis of complement-dependent HIV-1 cell infection using a model system.

Tacnet-Delorme P, Boyer V, Thielens NM, Hernandez JF, Bally I, Sim RB, Desgranges C, Arlaud GJ.

J Immunol. 1999 Apr 1;162(7):4088-93.

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