Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 93


Resistance of Leishmania (Viannia) Panamensis to Meglumine Antimoniate or Miltefosine Modulates Neutrophil Effector Functions.

Regli IB, Fernández OL, Martínez-Salazar B, Gómez MA, Saravia NG, Tacchini-Cottier F.

Front Immunol. 2018 Dec 21;9:3040. doi: 10.3389/fimmu.2018.03040. eCollection 2018.


TLR2 Signaling in Skin Nonhematopoietic Cells Induces Early Neutrophil Recruitment in Response to Leishmania major Infection.

Ronet C, Passelli K, Charmoy M, Scarpellino L, Myburgh E, Hauyon La Torre Y, Turco S, Mottram JC, Fasel N, Luther SA, Beverley SM, Launois P, Tacchini-Cottier F.

J Invest Dermatol. 2019 Jun;139(6):1318-1328. doi: 10.1016/j.jid.2018.12.012. Epub 2018 Dec 27.


Deletion of Interleukin-4 Receptor Alpha-Responsive Keratinocytes in BALB/c Mice Does Not Alter Susceptibility to Cutaneous Leishmaniasis.

Govender M, Hurdayal R, Martinez-Salazar B, Gqada K, Pillay S, Gcanga L, Passelli K, Nieuwenhuizen NE, Tacchini-Cottier F, Guler R, Brombacher F.

Infect Immun. 2018 Nov 20;86(12). pii: e00710-18. doi: 10.1128/IAI.00710-18. Print 2018 Dec.


Neutrophils enhance early Trypanosoma brucei infection onset.

Caljon G, Mabille D, Stijlemans B, De Trez C, Mazzone M, Tacchini-Cottier F, Malissen M, Van Ginderachter JA, Magez S, De Baetselier P, Van Den Abbeele J.

Sci Rep. 2018 Jul 25;8(1):11203. doi: 10.1038/s41598-018-29527-y.


Survival Mechanisms Used by Some Leishmania Species to Escape Neutrophil Killing.

Regli IB, Passelli K, Hurrell BP, Tacchini-Cottier F.

Front Immunol. 2017 Nov 16;8:1558. doi: 10.3389/fimmu.2017.01558. eCollection 2017. Review.


IL-4Rα Signaling in Keratinocytes and Early IL-4 Production Are Dispensable for Generating a Curative T Helper 1 Response in Leishmania major-Infected C57BL/6 Mice.

Descatoire M, Hurrell BP, Govender M, Passelli K, Martinez-Salazar B, Hurdayal R, Brombacher F, Guler R, Tacchini-Cottier F.

Front Immunol. 2017 Oct 10;8:1265. doi: 10.3389/fimmu.2017.01265. eCollection 2017.


Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis.

Jain V, Yogavel M, Kikuchi H, Oshima Y, Hariguchi N, Matsumoto M, Goel P, Touquet B, Jumani RS, Tacchini-Cottier F, Harlos K, Huston CD, Hakimi MA, Sharma A.

Structure. 2017 Oct 3;25(10):1495-1505.e6. doi: 10.1016/j.str.2017.07.015. Epub 2017 Aug 31.


Frontline Science: Leishmania mexicana amastigotes can replicate within neutrophils.

Hurrell BP, Beaumann M, Heyde S, Regli IB, Müller AJ, Tacchini-Cottier F.

J Leukoc Biol. 2017 Nov;102(5):1187-1198. doi: 10.1189/jlb.4HI0417-158R. Epub 2017 Aug 10.


Notch regulates Th17 differentiation and controls trafficking of IL-17 and metabolic regulators within Th17 cells in a context-dependent manner.

Coutaz M, Hurrell BP, Auderset F, Wang H, Siegert S, Eberl G, Ho PC, Radtke F, Tacchini-Cottier F.

Sci Rep. 2016 Dec 15;6:39117. doi: 10.1038/srep39117.


Notch Signaling Regulates the Homeostasis of Tissue-Restricted Innate-like T Cells.

Chennupati V, Koch U, Coutaz M, Scarpellino L, Tacchini-Cottier F, Luther SA, Radtke F, Zehn D, MacDonald HR.

J Immunol. 2016 Aug 1;197(3):771-82. doi: 10.4049/jimmunol.1501675. Epub 2016 Jun 20.


Different Leishmania Species Drive Distinct Neutrophil Functions.

Hurrell BP, Regli IB, Tacchini-Cottier F.

Trends Parasitol. 2016 May;32(5):392-401. doi: 10.1016/ Epub 2016 Mar 1. Review.


The Nlrp3 inflammasome, IL-1β, and neutrophil recruitment are required for susceptibility to a nonhealing strain of Leishmania major in C57BL/6 mice.

Charmoy M, Hurrell BP, Romano A, Lee SH, Ribeiro-Gomes F, Riteau N, Mayer-Barber K, Tacchini-Cottier F, Sacks DL.

Eur J Immunol. 2016 Apr;46(4):897-911. doi: 10.1002/eji.201546015. Epub 2016 Jan 20.


NLRP12 is a neutrophil-specific, negative regulator of in vitro cell migration but does not modulate LPS- or infection-induced NF-κB or ERK signalling.

Zamoshnikova A, Groß CJ, Schuster S, Chen KW, Wilson A, Tacchini-Cottier F, Schroder K.

Immunobiology. 2016 Feb;221(2):341-6. doi: 10.1016/j.imbio.2015.10.001. Epub 2015 Oct 23.


Rapid Sequestration of Leishmania mexicana by Neutrophils Contributes to the Development of Chronic Lesion.

Hurrell BP, Schuster S, Grün E, Coutaz M, Williams RA, Held W, Malissen B, Malissen M, Yousefi S, Simon HU, Müller AJ, Tacchini-Cottier F.

PLoS Pathog. 2015 May 28;11(5):e1004929. doi: 10.1371/journal.ppat.1004929. eCollection 2015 May.


Exposure to Leishmania braziliensis triggers neutrophil activation and apoptosis.

Falcão SA, Weinkopff T, Hurrell BP, Celes FS, Curvelo RP, Prates DB, Barral A, Borges VM, Tacchini-Cottier F, de Oliveira CI.

PLoS Negl Trop Dis. 2015 Mar 10;9(3):e0003601. doi: 10.1371/journal.pntd.0003601. eCollection 2015 Mar.


Blocking junctional adhesion molecule C enhances dendritic cell migration and boosts the immune responses against Leishmania major.

Ballet R, Emre Y, Jemelin S, Charmoy M, Tacchini-Cottier F, Imhof BA.

PLoS Pathog. 2014 Dec 4;10(12):e1004550. doi: 10.1371/journal.ppat.1004550. eCollection 2014 Dec.


Specific fibroblastic niches in secondary lymphoid organs orchestrate distinct Notch-regulated immune responses.

Fasnacht N, Huang HY, Koch U, Favre S, Auderset F, Chai Q, Onder L, Kallert S, Pinschewer DD, MacDonald HR, Tacchini-Cottier F, Ludewig B, Luther SA, Radtke F.

J Exp Med. 2014 Oct 20;211(11):2265-79. doi: 10.1084/jem.20132528. Epub 2014 Oct 13.


Activated group 3 innate lymphoid cells promote T-cell-mediated immune responses.

von Burg N, Chappaz S, Baerenwaldt A, Horvath E, Bose Dasgupta S, Ashok D, Pieters J, Tacchini-Cottier F, Rolink A, Acha-Orbea H, Finke D.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12835-40. doi: 10.1073/pnas.1406908111. Epub 2014 Aug 18.


A scoring method to standardize lesion monitoring following intra-dermal infection of Leishmania parasites in the murine ear.

Schuster S, Hartley MA, Tacchini-Cottier F, Ronet C.

Front Cell Infect Microbiol. 2014 May 28;4:67. doi: 10.3389/fcimb.2014.00067. eCollection 2014. No abstract available.


Cross-presenting dendritic cells are required for control of Leishmania major infection.

Ashok D, Schuster S, Ronet C, Rosa M, Mack V, Lavanchy C, Marraco SF, Fasel N, Murphy KM, Tacchini-Cottier F, Acha-Orbea H.

Eur J Immunol. 2014 May;44(5):1422-32. doi: 10.1002/eji.201344242. Epub 2014 Mar 25.


TREM-1 deficiency can attenuate disease severity without affecting pathogen clearance.

Weber B, Schuster S, Zysset D, Rihs S, Dickgreber N, Schürch C, Riether C, Siegrist M, Schneider C, Pawelski H, Gurzeler U, Ziltener P, Genitsch V, Tacchini-Cottier F, Ochsenbein A, Hofstetter W, Kopf M, Kaufmann T, Oxenius A, Reith W, Saurer L, Mueller C.

PLoS Pathog. 2014 Jan;10(1):e1003900. doi: 10.1371/journal.ppat.1003900. Epub 2014 Jan 16.


Repeated exposure to Lutzomyia intermedia sand fly saliva induces local expression of interferon-inducible genes both at the site of injection in mice and in human blood.

Weinkopff T, de Oliveira CI, de Carvalho AM, Hauyon-La Torre Y, Muniz AC, Miranda JC, Barral A, Tacchini-Cottier F.

PLoS Negl Trop Dis. 2014 Jan 9;8(1):e2627. doi: 10.1371/journal.pntd.0002627. eCollection 2014.


Trapping of naive lymphocytes triggers rapid growth and remodeling of the fibroblast network in reactive murine lymph nodes.

Yang CY, Vogt TK, Favre S, Scarpellino L, Huang HY, Tacchini-Cottier F, Luther SA.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):E109-18. doi: 10.1073/pnas.1312585111. Epub 2013 Dec 23.


Notch signaling regulates follicular helper T cell differentiation.

Auderset F, Schuster S, Fasnacht N, Coutaz M, Charmoy M, Koch U, Favre S, Wilson A, Trottein F, Alexander J, Luther SA, MacDonald HR, Radtke F, Tacchini-Cottier F.

J Immunol. 2013 Sep 1;191(5):2344-50. doi: 10.4049/jimmunol.1300643. Epub 2013 Aug 5.


Regulation of innate and adaptive immunity by Notch.

Radtke F, MacDonald HR, Tacchini-Cottier F.

Nat Rev Immunol. 2013 Jun;13(6):427-37. doi: 10.1038/nri3445. Epub 2013 May 13. Review.


Arginase activity - a marker of disease status in patients with visceral leishmaniasis in ethiopia.

Abebe T, Takele Y, Weldegebreal T, Cloke T, Closs E, Corset C, Hailu A, Hailu W, Sisay Y, Corware K, Corset M, Modolell M, Munder M, Tacchini-Cottier F, Müller I, Kropf P.

PLoS Negl Trop Dis. 2013;7(3):e2134. doi: 10.1371/journal.pntd.0002134. Epub 2013 Mar 28.


Role of Toll-like receptor 9 signaling in experimental Leishmania braziliensis infection.

Weinkopff T, Mariotto A, Simon G, Hauyon-La Torre Y, Auderset F, Schuster S, Zangger H, Fasel N, Barral A, Tacchini-Cottier F.

Infect Immun. 2013 May;81(5):1575-84. doi: 10.1128/IAI.01401-12. Epub 2013 Feb 25.


Arginase activity in the blood of patients with visceral leishmaniasis and HIV infection.

Takele Y, Abebe T, Weldegebreal T, Hailu A, Hailu W, Hurissa Z, Ali J, Diro E, Sisay Y, Cloke T, Modolell M, Munder M, Tacchini-Cottier F, Müller I, Kropf P.

PLoS Negl Trop Dis. 2013;7(1):e1977. doi: 10.1371/journal.pntd.0001977. Epub 2013 Jan 17. Erratum in: PLoS Negl Trop Dis. 2013 Jan;7(1). doi: 10.1371/annotation/9e89dee8-e2b7-4559-bd4e-933692403410.


Crosstalk between neutrophils and dendritic cells: a context-dependent process.

Schuster S, Hurrell B, Tacchini-Cottier F.

J Leukoc Biol. 2013 Oct;94(4):671-5. doi: 10.1189/jlb.1012540. Epub 2012 Dec 18. Review.


Environmental and T cell-intrinsic factors limit the expansion of neonatal follicular T helper cells but may be circumvented by specific adjuvants.

Mastelic B, Kamath AT, Fontannaz P, Tougne C, Rochat AF, Belnoue E, Combescure C, Auderset F, Lambert PH, Tacchini-Cottier F, Siegrist CA.

J Immunol. 2012 Dec 15;189(12):5764-72. doi: 10.4049/jimmunol.1201143. Epub 2012 Nov 16.


Local increase of arginase activity in lesions of patients with cutaneous leishmaniasis in Ethiopia.

Abebe T, Hailu A, Woldeyes M, Mekonen W, Bilcha K, Cloke T, Fry L, Seich Al Basatena NK, Corware K, Modolell M, Munder M, Tacchini-Cottier F, Müller I, Kropf P.

PLoS Negl Trop Dis. 2012;6(6):e1684. doi: 10.1371/journal.pntd.0001684. Epub 2012 Jun 12.


The role of Notch in the differentiation of CD4⁺ T helper cells.

Auderset F, Coutaz M, Tacchini-Cottier F.

Curr Top Microbiol Immunol. 2012;360:115-34. doi: 10.1007/82_2012_227. Review.


Does T Helper Differentiation Correlate with Resistance or Susceptibility to Infection with L. major? Some Insights From the Murine Model.

Tacchini-Cottier F, Weinkopff T, Launois P.

Front Immunol. 2012 Feb 27;3:32. doi: 10.3389/fimmu.2012.00032. eCollection 2012.


Differential peptide binding to CD40 evokes counteractive responses.

Khan S, Alonso-Sarduy L, Roduit C, Bandyopadhyay S, Singh S, Saha S, Tacchini-Cottier F, Roy S, Dietler G, Kasas S, Das P, Krishnasastry MV, Saha B.

Hum Immunol. 2012 May;73(5):465-9. doi: 10.1016/j.humimm.2012.02.017. Epub 2012 Mar 1. Erratum in: Hum Immunol. 2012 Nov;73(11):1210. Alonso, Livan [corrected to Alonso-Sarduy, Livan].


Redundant Notch1 and Notch2 signaling is necessary for IFNγ secretion by T helper 1 cells during infection with Leishmania major.

Auderset F, Schuster S, Coutaz M, Koch U, Desgranges F, Merck E, MacDonald HR, Radtke F, Tacchini-Cottier F.

PLoS Pathog. 2012;8(3):e1002560. doi: 10.1371/journal.ppat.1002560. Epub 2012 Mar 1.


Amine-reactive OVA multimers for auto-vaccination against cytokines and other mediators: perspectives illustrated for GCP-2 in L. major infection.

Uyttenhove C, Marillier RG, Tacchini-Cottier F, Charmoy M, Caspi RR, Damsker JM, Goriely S, Su D, Van Damme J, Struyf S, Opdenakker G, Van Snick J.

J Leukoc Biol. 2011 Jun;89(6):1001-7. doi: 10.1189/jlb.1210699. Epub 2011 Mar 8.


The MyD88 protein 88 pathway is differently involved in immune responses induced by distinct substrains of Leishmania major.

Revaz-Breton M, Ronet C, Ives A, Torre YH, Masina S, Tacchini-Cottier F, Launois P.

Eur J Immunol. 2010 Jun;40(6):1697-707. doi: 10.1002/eji.200939821.


Neutrophil-derived CCL3 is essential for the rapid recruitment of dendritic cells to the site of Leishmania major inoculation in resistant mice.

Charmoy M, Brunner-Agten S, Aebischer D, Auderset F, Launois P, Milon G, Proudfoot AE, Tacchini-Cottier F.

PLoS Pathog. 2010 Feb 5;6(2):e1000755. doi: 10.1371/journal.ppat.1000755.


Regulatory B cells shape the development of Th2 immune responses in BALB/c mice infected with Leishmania major through IL-10 production.

Ronet C, Hauyon-La Torre Y, Revaz-Breton M, Mastelic B, Tacchini-Cottier F, Louis J, Launois P.

J Immunol. 2010 Jan 15;184(2):886-94. doi: 10.4049/jimmunol.0901114. Epub 2009 Dec 4.


Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies.

Fiorini E, Merck E, Wilson A, Ferrero I, Jiang W, Koch U, Auderset F, Laurenti E, Tacchini-Cottier F, Pierres M, Radtke F, Luther SA, Macdonald HR.

J Immunol. 2009 Dec 1;183(11):7212-22. doi: 10.4049/jimmunol.0902432. Epub 2009 Nov 13.


The prominent role of neutrophils during the initial phase of infection by Leishmania parasites.

Charmoy M, Auderset F, Allenbach C, Tacchini-Cottier F.

J Biomed Biotechnol. 2010;2010:719361. doi: 10.1155/2010/719361. Epub 2009 Oct 25. Review.


A new function of the Fas-FasL pathway in macrophage activation.

Chakour R, Allenbach C, Desgranges F, Charmoy M, Mauel J, Garcia I, Launois P, Louis J, Tacchini-Cottier F.

J Leukoc Biol. 2009 Jul;86(1):81-90. doi: 10.1189/jlb.1008590. Epub 2009 Apr 20.


Intralesional regulatory T-cell suppressive function during human acute and chronic cutaneous leishmaniasis due to Leishmania guyanensis.

Bourreau E, Ronet C, Darcissac E, Lise MC, Sainte Marie D, Clity E, Tacchini-Cottier F, Couppie P, Launois P.

Infect Immun. 2009 Apr;77(4):1465-74. doi: 10.1128/IAI.01398-08. Epub 2009 Jan 21.


In leishmaniasis due to Leishmania guyanensis infection, distinct intralesional interleukin-10 and Foxp3 mRNA expression are associated with unresponsiveness to treatment.

Bourreau E, Ronet C, Darsissac E, Lise MC, Marie DS, Clity E, Tacchini-Cottier F, Couppie P, Launois P.

J Infect Dis. 2009 Feb 15;199(4):576-9. doi: 10.1086/596508.


Cutaneous leishmaniasis: progress towards a vaccine.

Launois P, Tacchini-Cottier F, Kieny MP.

Expert Rev Vaccines. 2008 Oct;7(8):1277-87. doi: 10.1586/14760584.7.8.1277. Review.


Leishmania major-specific B cells are necessary for Th2 cell development and susceptibility to L. major LV39 in BALB/c mice.

Ronet C, Voigt H, Himmelrich H, Doucey MA, Hauyon-La Torre Y, Revaz-Breton M, Tacchini-Cottier F, Bron C, Louis J, Launois P.

J Immunol. 2008 Apr 1;180(7):4825-35.


An essential role for transmembrane TNF in the resolution of the inflammatory lesion induced by Leishmania major infection.

Allenbach C, Launois P, Mueller C, Tacchini-Cottier F.

Eur J Immunol. 2008 Mar;38(3):720-31. doi: 10.1002/eji.200737662.


Neutrophils contribute to development of a protective immune response during onset of infection with Leishmania donovani.

McFarlane E, Perez C, Charmoy M, Allenbach C, Carter KC, Alexander J, Tacchini-Cottier F.

Infect Immun. 2008 Feb;76(2):532-41. Epub 2007 Dec 3.


Interleukin-12p40 overexpression promotes interleukin-12p70 and interleukin-23 formation but does not affect bacille Calmette-Guérin and Mycobacterium tuberculosis clearance.

Olleros ML, Vesin D, Martinez-Soria E, Allenbach C, Tacchini-Cottier F, Pache JC, Marchal G, Rahman J, Fernández C, Izui S, Garcia I.

Immunology. 2007 Nov;122(3):350-61. Epub 2007 Jul 9.


IL-10 producing CD8+ T cells in human infection with Leishmania guyanensis.

Bourreau E, Ronet C, Couppié P, Sainte-Marie D, Tacchini-Cottier F, Launois P.

Microbes Infect. 2007 Jul;9(8):1034-41. Epub 2007 Apr 21.


Supplemental Content

Loading ...
Support Center