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Items: 1 to 50 of 132

1.

Response.

Collins FS, Tabak LA, Wolinetz CD, Lauer MS, Gottesman MM.

Science. 2019 Mar 22;363(6433):1292-1294. doi: 10.1126/science.aaw8810. No abstract available.

2.

The Partnership for Accelerating Cancer Therapies.

Baker RG, Hoos AX, Adam SJ, Wholley D, Doroshow JH, Lowy DR, Tabak LA, Collins FS.

Cancer J. 2018 May/Jun;24(3):111-114. doi: 10.1097/PPO.0000000000000321. Review.

3.

A molecular switch orchestrates enzyme specificity and secretory granule morphology.

Ji S, Samara NL, Revoredo L, Zhang L, Tran DT, Muirhead K, Tabak LA, Ten Hagen KG.

Nat Commun. 2018 Aug 29;9(1):3508. doi: 10.1038/s41467-018-05978-9.

4.

Members of the GalNAc-T family of enzymes utilize distinct Golgi localization mechanisms.

Becker JL, Tran DT, Tabak LA.

Glycobiology. 2018 Nov 1;28(11):841-848. doi: 10.1093/glycob/cwy071.

5.

The GalNAc-T Activation Pathway (GALA) is not a general mechanism for regulating mucin-type O-glycosylation.

Herbomel GG, Rojas RE, Tran DT, Ajinkya M, Beck L, Tabak LA.

PLoS One. 2017 Jul 18;12(7):e0179241. doi: 10.1371/journal.pone.0179241. eCollection 2017.

6.

Characterization and expression analysis of Galnts in developing Strongylocentrotus purpuratus embryos.

Famiglietti AL, Wei Z, Beres TM, Milac AL, Tran DT, Patel D, Angerer RC, Angerer LM, Tabak LA.

PLoS One. 2017 Apr 27;12(4):e0176479. doi: 10.1371/journal.pone.0176479. eCollection 2017.

7.

Basic science: Bedrock of progress.

Collins FS, Anderson JM, Austin CP, Battey JF, Birnbaum LS, Briggs JP, Clayton JA, Cuthbert B, Eisinger RW, Fauci AS, Gallin JI, Gibbons GH, Glass RI, Gottesman MM, Gray PA, Green ED, Greider FB, Hodes R, Hudson KL, Humphreys B, Katz SI, Koob GF, Koroshetz WJ, Lauer MS, Lorsch JR, Lowy DR, McGowan JJ, Murray DM, Nakamura R, Norris A, Perez-Stable EJ, Pettigrew RI, Riley WT, Rodgers GP, Sieving PA, Somerman MJ, Spong CY, Tabak LA, Volkow ND, Wilder EL.

Science. 2016 Mar 25;351(6280):1405. doi: 10.1126/science.351.6280.1405-a. No abstract available.

8.

Mucin-type O-glycosylation is controlled by short- and long-range glycopeptide substrate recognition that varies among members of the polypeptide GalNAc transferase family.

Revoredo L, Wang S, Bennett EP, Clausen H, Moremen KW, Jarvis DL, Ten Hagen KG, Tabak LA, Gerken TA.

Glycobiology. 2016 Apr;26(4):360-76. doi: 10.1093/glycob/cwv108. Epub 2015 Nov 26.

9.

Erratum: UDP-N-acetyl-α-D-galactosamine: polypeptide N-acetylgalactosaminyltransferases: completion of the family tree.

Raman J, Guan Y, Perrine CL, Gerken TA, Tabak LA.

Glycobiology. 2015 Apr;25(4):465. doi: 10.1093/glycob/cwv003. No abstract available.

10.

Galnt1 is required for normal heart valve development and cardiac function.

Tian E, Stevens SR, Guan Y, Springer DA, Anderson SA, Starost MF, Patel V, Ten Hagen KG, Tabak LA.

PLoS One. 2015 Jan 23;10(1):e0115861. doi: 10.1371/journal.pone.0115861. eCollection 2015.

11.

National Institutes of Health efforts on sexual and gender minority health research.

Tabak LA.

Am J Public Health. 2014 Jul;104(7):e7. doi: 10.2105/AJPH.2014.301973. Epub 2014 May 15. No abstract available.

12.

A computational and experimental study of O-glycosylation. Catalysis by human UDP-GalNAc polypeptide:GalNAc transferase-T2.

Gómez H, Rojas R, Patel D, Tabak LA, Lluch JM, Masgrau L.

Org Biomol Chem. 2014 May 7;12(17):2645-55. doi: 10.1039/c3ob42569j.

13.

Policy: NIH plans to enhance reproducibility.

Collins FS, Tabak LA.

Nature. 2014 Jan 30;505(7485):612-3. No abstract available.

14.

Biomedical research: strength from diversity.

Wilder EL, Tabak LA, Pettigrew RI, Collins FS.

Science. 2013 Nov 15;342(6160):798. doi: 10.1126/science.342.6160.798-a. No abstract available.

15.

The lectin domain of the polypeptide GalNAc transferase family of glycosyltransferases (ppGalNAc Ts) acts as a switch directing glycopeptide substrate glycosylation in an N- or C-terminal direction, further controlling mucin type O-glycosylation.

Gerken TA, Revoredo L, Thome JJ, Tabak LA, Vester-Christensen MB, Clausen H, Gahlay GK, Jarvis DL, Johnson RW, Moniz HA, Moremen K.

J Biol Chem. 2013 Jul 5;288(27):19900-14. doi: 10.1074/jbc.M113.477877. Epub 2013 May 20.

16.

Research funding. A framework for decisions about research with HPAI H5N1 viruses.

Patterson AP, Tabak LA, Fauci AS, Collins FS, Howard S.

Science. 2013 Mar 1;339(6123):1036-7. doi: 10.1126/science.1236194. Epub 2013 Feb 21. No abstract available.

17.

UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyltransferases: completion of the family tree.

Raman J, Guan Y, Perrine CL, Gerken TA, Tabak LA.

Glycobiology. 2012 Jun;22(6):768-77. doi: 10.1093/glycob/cwr183. Epub 2011 Dec 20. Erratum in: Glycobiology. 2015 Apr;25(4):465.

18.

Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family.

Bennett EP, Mandel U, Clausen H, Gerken TA, Fritz TA, Tabak LA.

Glycobiology. 2012 Jun;22(6):736-56. doi: 10.1093/glycob/cwr182. Epub 2011 Dec 18. Review.

19.

Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man.

Holleboom AG, Karlsson H, Lin RS, Beres TM, Sierts JA, Herman DS, Stroes ES, Aerts JM, Kastelein JJ, Motazacker MM, Dallinga-Thie GM, Levels JH, Zwinderman AH, Seidman JG, Seidman CE, Ljunggren S, Lefeber DJ, Morava E, Wevers RA, Fritz TA, Tabak LA, Lindahl M, Hovingh GK, Kuivenhoven JA.

Cell Metab. 2011 Dec 7;14(6):811-8. doi: 10.1016/j.cmet.2011.11.005.

20.

Sociology. Weaving a richer tapestry in biomedical science.

Tabak LA, Collins FS.

Science. 2011 Aug 19;333(6045):940-1. doi: 10.1126/science.1211704. No abstract available.

21.

Global oral health inequalities: the view from a research funder.

Garcia I, Tabak LA.

Adv Dent Res. 2011 May;23(2):207-10. doi: 10.1177/0022034511402015.

22.

Emerging paradigms for the initiation of mucin-type protein O-glycosylation by the polypeptide GalNAc transferase family of glycosyltransferases.

Gerken TA, Jamison O, Perrine CL, Collette JC, Moinova H, Ravi L, Markowitz SD, Shen W, Patel H, Tabak LA.

J Biol Chem. 2011 Apr 22;286(16):14493-507. doi: 10.1074/jbc.M111.218701. Epub 2011 Feb 24.

23.

Human oral microbiology is at a crossroads.

Lunsford RD, Tabak LA.

Mol Oral Microbiol. 2010 Feb;25(1):3. doi: 10.1111/j.2041-1014.2009.00557.x. No abstract available.

24.

The role of mucin-type O-glycans in eukaryotic development.

Tabak LA.

Semin Cell Dev Biol. 2010 Aug;21(6):616-21. doi: 10.1016/j.semcdb.2010.02.001. Epub 2010 Feb 6. Review.

25.

Isoform-specific O-glycosylation of osteopontin and bone sialoprotein by polypeptide N-acetylgalactosaminyltransferase-1.

Miwa HE, Gerken TA, Jamison O, Tabak LA.

J Biol Chem. 2010 Jan 8;285(2):1208-19. doi: 10.1074/jbc.M109.035436. Epub 2009 Oct 30.

26.

A view of the future: dentistry and oral health in America.

Garcia I, Tabak LA.

J Am Dent Assoc. 2009 Sep;140 Suppl 1:44S-48S.

27.

Glycopeptide-preferring polypeptide GalNAc transferase 10 (ppGalNAc T10), involved in mucin-type O-glycosylation, has a unique GalNAc-O-Ser/Thr-binding site in its catalytic domain not found in ppGalNAc T1 or T2.

Perrine CL, Ganguli A, Wu P, Bertozzi CR, Fritz TA, Raman J, Tabak LA, Gerken TA.

J Biol Chem. 2009 Jul 24;284(30):20387-97. doi: 10.1074/jbc.M109.017236. Epub 2009 May 21.

28.

The catalytic and lectin domains of UDP-GalNAc:polypeptide alpha-N-Acetylgalactosaminyltransferase function in concert to direct glycosylation site selection.

Raman J, Fritz TA, Gerken TA, Jamison O, Live D, Liu M, Tabak LA.

J Biol Chem. 2008 Aug 22;283(34):22942-51. doi: 10.1074/jbc.M803387200. Epub 2008 Jun 18.

29.

Facing the future: the NIDCR celebrates its 60th Anniversary.

Garcia AI, Tabak LA.

J Dent Res. 2008 Jun;87(6):509. No abstract available.

30.

Genetics and its implications for clinical dental practice and education: report of panel 3 of the Macy study.

Johnson L, Genco RJ, Damsky C, Haden NK, Hart S, Hart TC, Shuler CF, Tabak LA, tedesco LA.

J Dent Educ. 2008 Feb;72(2 Suppl):86-94. No abstract available.

31.

Beyond the "omics": translating science into improved health.

Garcia I, Tabak LA.

J Am Dent Assoc. 2008 Apr;139(4):392-5. No abstract available.

32.

An inhibitor of O-glycosylation induces apoptosis in NIH3T3 cells and developing mouse embryonic mandibular tissues.

Tian E, Ten Hagen KG, Shum L, Hang HC, Imbert Y, Young WW Jr, Bertozzi CR, Tabak LA.

J Biol Chem. 2008 Feb 15;283(7):4460. No abstract available.

33.

Initiation of protein O glycosylation by the polypeptide GalNAcT-1 in vascular biology and humoral immunity.

Tenno M, Ohtsubo K, Hagen FK, Ditto D, Zarbock A, Schaerli P, von Andrian UH, Ley K, Le D, Tabak LA, Marth JD.

Mol Cell Biol. 2007 Dec;27(24):8783-96. Epub 2007 Oct 8.

34.

Substrate-induced conformational changes and dynamics of UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferase-2.

Milac AL, Buchete NV, Fritz TA, Hummer G, Tabak LA.

J Mol Biol. 2007 Oct 19;373(2):439-51. Epub 2007 Aug 21.

35.

Point-of-care diagnostics enter the mouth.

Tabak LA.

Ann N Y Acad Sci. 2007 Mar;1098:7-14. Epub 2007 Feb 15. Review.

PMID:
17303835
36.

In defense of the oral cavity: the protective role of the salivary secretions.

Tabak LA.

Pediatr Dent. 2006 Mar-Apr;28(2):110-7; discussion 192-8. Review.

PMID:
16708785
37.

Response to: "Rescuing the NIH before it is too late".

Alexander DF, Alving BM, Battey JF, Berg JM, Collins FS, Fauci AS, Gallin JI, Grady PA, Hodes RJ, Hrynkow SH, Insel TR, Jones JF, Katz SI, Landis SC, Li TK, Lindberg DA, Nabel EG, Niederhuber JE, Pettigrew RI, Rodgers GP, Ruffin J, Scarpa A, Schwartz DA, Sieving PA, Straus SE, Tabak LA, Volkow ND.

J Clin Invest. 2006 Jun;116(6):1462-3.

38.

Dynamic association between the catalytic and lectin domains of human UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase-2.

Fritz TA, Raman J, Tabak LA.

J Biol Chem. 2006 Mar 31;281(13):8613-9. Epub 2006 Jan 24. Erratum in: J Biol Chem. 2006 Aug 25;281(34):25000.

39.

NIH Roadmap interdisciplinary research initiatives.

Huerta MF, Farber GK, Wilder EL, Kleinman DV, Grady PA, Schwartz DA, Tabak LA.

PLoS Comput Biol. 2005 Nov;1(6):e59. No abstract available.

40.

Dentistry on the road(map).

Tabak LA.

J Am Dent Assoc. 2004 Oct;135(10):1362, 1364, 1366. No abstract available.

PMID:
15551971
41.

The beginnings of mucin biosynthesis: the crystal structure of UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase-T1.

Fritz TA, Hurley JH, Trinh LB, Shiloach J, Tabak LA.

Proc Natl Acad Sci U S A. 2004 Oct 26;101(43):15307-12. Epub 2004 Oct 14.

42.

Oral health research at the crossroads: translate we must!

Hart TC, Pihlstrom BL, Tabak LA.

J Endod. 2004 Oct;30(10):684-8. Review. No abstract available.

PMID:
15448459
43.

An inhibitor of O-glycosylation induces apoptosis in NIH3T3 cells and developing mouse embryonic mandibular tissues.

Tian E, Ten Hagen KG, Shum L, Hang HC, Imbert Y, Young WW Jr, Bertozzi CR, Tabak LA.

J Biol Chem. 2004 Nov 26;279(48):50382-90. Epub 2004 Sep 1. Retraction in: Tian E, Ten Hagen KG, Shum L, Hang HC, Imbert Y, Young WW Jr, Bertozzi CR, Tabak LA. J Biol Chem. 2008 Feb 15;283(7):4460.

44.

Deconvoluting the functions of polypeptide N-alpha-acetylgalactosaminyltransferase family members by glycopeptide substrate profiling.

Pratt MR, Hang HC, Ten Hagen KG, Rarick J, Gerken TA, Tabak LA, Bertozzi CR.

Chem Biol. 2004 Jul;11(7):1009-16.

45.

Small molecule inhibitors of mucin-type O-linked glycosylation from a uridine-based library.

Hang HC, Yu C, Ten Hagen KG, Tian E, Winans KA, Tabak LA, Bertozzi CR.

Chem Biol. 2004 Mar;11(3):337-45.

46.

Dental, oral, and craniofacial research: the view from the NIDCR.

Tabak LA.

J Dent Res. 2004 Mar;83(3):196-7. No abstract available.

PMID:
14981117
47.

Expression of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase isoforms in murine tissues determined by real-time PCR: a new view of a large family.

Young WW Jr, Holcomb DR, Ten Hagen KG, Tabak LA.

Glycobiology. 2003 Jul;13(7):549-57. Epub 2003 Mar 19.

PMID:
12651884
48.

All in the family: the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferases.

Ten Hagen KG, Fritz TA, Tabak LA.

Glycobiology. 2003 Jan;13(1):1R-16R. Epub 2002 Nov 1. Review.

PMID:
12634319
49.

New directions in dentistry--the role of the National Institute of Dental and Craniofacial Research.

Tabak LA.

J Periodontol. 2003 Jan;74(1):65. No abstract available.

PMID:
12593598
50.

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