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Items: 35


Microfibrillar-associated protein 4: a potential biomarker of chronic obstructive pulmonary disease.

Johansson SL, Roberts NB, Schlosser A, Andersen CB, Carlsen J, Wulf-Johansson H, Sækmose SG, Titlestad IL, Tornoe I, Miller B, Tal-Singer R, Holmskov U, Vestbo J, Sorensen GL.

Respir Med. 2014 Sep;108(9):1336-44. doi: 10.1016/j.rmed.2014.06.003. Epub 2014 Jun 20.


Localization of microfibrillar-associated protein 4 (MFAP4) in human tissues: clinical evaluation of serum MFAP4 and its association with various cardiovascular conditions.

Wulf-Johansson H, Lock Johansson S, Schlosser A, Trommelholt Holm A, Rasmussen LM, Mickley H, Diederichsen AC, Munkholm H, Poulsen TS, Tornøe I, Nielsen V, Marcussen N, Vestbo J, Sækmose SG, Holmskov U, Sorensen GL.

PLoS One. 2013 Dec 13;8(12):e82243. doi: 10.1371/journal.pone.0082243. eCollection 2013.


Enzyme-linked immunosorbent assay characterization of basal variation and heritability of systemic microfibrillar-associated protein 4.

Sækmose SG, Schlosser A, Holst R, Johansson SL, Wulf-Johansson H, Tornøe I, Vestbo J, Kyvik KO, Barington T, Holmskov U, Sørensen GL.

PLoS One. 2013 Dec 4;8(12):e82383. doi: 10.1371/journal.pone.0082383. eCollection 2013.


Surfactant protein D (SP-D) deficiency is attenuated in humanised mice expressing the Met(11)Thr short nucleotide polymorphism of SP-D: implications for surfactant metabolism in the lung.

Knudsen L, Ochs K, Boxler L, Tornoe I, Lykke-Sorensen G, Mackay RM, Clark HW, Holmskov U, Ochs M, Madsen J.

J Anat. 2013 Dec;223(6):581-92. doi: 10.1111/joa.12120. Epub 2013 Sep 23.


A variant form of the human deleted in malignant brain tumor 1 (DMBT1) gene shows increased expression in inflammatory bowel diseases and interacts with dimeric trefoil factor 3 (TFF3).

Madsen J, Sorensen GL, Nielsen O, Tornøe I, Thim L, Fenger C, Mollenhauer J, Holmskov U.

PLoS One. 2013 May 15;8(5):e64441. doi: 10.1371/journal.pone.0064441. Print 2013.


Identification and characterization of a chitin-binding protein purified from coelomic fluid of the lugworm Arenicola marina defining a novel protein sequence family.

Vitashenkova N, Moeller JB, Leth-Larsen R, Schlosser A, Lund KP, Tornøe I, Vitved L, Hansen S, Willis A, Kharazova AD, Skjødt K, Sorensen GL, Holmskov U.

J Biol Chem. 2012 Dec 14;287(51):42846-55. doi: 10.1074/jbc.M112.420976. Epub 2012 Oct 31.


CD163-L1 is an endocytic macrophage protein strongly regulated by mediators in the inflammatory response.

Moeller JB, Nielsen MJ, Reichhardt MP, Schlosser A, Sorensen GL, Nielsen O, Tornøe I, Grønlund J, Nielsen ME, Jørgensen JS, Jensen ON, Mollenhauer J, Moestrup SK, Holmskov U.

J Immunol. 2012 Mar 1;188(5):2399-409. doi: 10.4049/jimmunol.1103150. Epub 2012 Jan 25.


A simple two-step purification procedure for the iC3b binding collectin conglutinin.

Krogh-Meibom T, Ingvartsen KL, Tornoe I, Palaniyar N, Willis AC, Holmskov U.

J Immunol Methods. 2010 Oct 31;362(1-2):204-8. doi: 10.1016/j.jim.2010.09.010. Epub 2010 Sep 9.


Circadian rhythm and the influence of physical activity on circulating surfactant protein D in early and long-standing rheumatoid arthritis.

Christensen AF, Hoegh SV, Lottenburger T, Holmskov U, Tornoe I, Hørslev-Petersen K, Sørensen GL, Junker P.

Rheumatol Int. 2011 Dec;31(12):1617-23. doi: 10.1007/s00296-010-1538-7. Epub 2010 May 29.


Enhancement of antiviral activity of collectin trimers through cross-linking and mutagenesis of the carbohydrate recognition domain.

White MR, Boland P, Tecle T, Gantz D, Sorenson G, Tornoe I, Holmskov U, McDonald B, Crouch EC, Hartshorn KL.

J Innate Immun. 2010;2(3):267-79. doi: 10.1159/000272313. Epub 2009 Dec 24.


Characterization of FIBCD1 as an acetyl group-binding receptor that binds chitin.

Schlosser A, Thomsen T, Moeller JB, Nielsen O, Tornøe I, Mollenhauer J, Moestrup SK, Holmskov U.

J Immunol. 2009 Sep 15;183(6):3800-9. doi: 10.4049/jimmunol.0901526. Epub 2009 Aug 26.


Multimeric and trimeric subunit SP-D are interconvertible structures with distinct ligand interaction.

Sorensen GL, Hoegh SV, Leth-Larsen R, Thomsen TH, Floridon C, Smith K, Kejling K, Tornoe I, Crouch EC, Holmskov U.

Mol Immunol. 2009 Sep;46(15):3060-9. doi: 10.1016/j.molimm.2009.06.005. Epub 2009 Jul 3.


Long-term stability and circadian variation in circulating levels of surfactant protein D.

Hoegh SV, Sorensen GL, Tornoe I, Lottenburger T, Ytting H, Nielsen HJ, Junker P, Holmskov U.

Immunobiology. 2010 Apr;215(4):314-20. doi: 10.1016/j.imbio.2009.05.001. Epub 2009 Jun 21.


Detection of novel biomarkers of liver cirrhosis by proteomic analysis.

Mölleken C, Sitek B, Henkel C, Poschmann G, Sipos B, Wiese S, Warscheid B, Broelsch C, Reiser M, Friedman SL, Tornøe I, Schlosser A, Klöppel G, Schmiegel W, Meyer HE, Holmskov U, Stühler K.

Hepatology. 2009 Apr;49(4):1257-66. doi: 10.1002/hep.22764.


Plasma surfactant protein D levels and the relation to body mass index in a chinese population.

Zhao XM, Wu YP, Wei R, Cai HX, Tornoe I, Han JJ, Wang Y, De Groot PG, Holmskov U, Xia ZL, Sorensen GL.

Scand J Immunol. 2007 Jul;66(1):71-76. doi: 10.1111/j.1365-3083.2007.01943.x.


Reduced influenza viral neutralizing activity of natural human trimers of surfactant protein D.

Hartshorn KL, White MR, Tecle T, Tornoe I, Sorensen GL, Crouch EC, Holmskov U.

Respir Res. 2007 Feb 5;8:9.


Tissue localization of human trefoil factors 1, 2, and 3.

Madsen J, Nielsen O, Tornøe I, Thim L, Holmskov U.

J Histochem Cytochem. 2007 May;55(5):505-13. Epub 2007 Jan 22.


Microfibril-associated protein 4 binds to surfactant protein A (SP-A) and colocalizes with SP-A in the extracellular matrix of the lung.

Schlosser A, Thomsen T, Shipley JM, Hein PW, Brasch F, Tornøe I, Nielsen O, Skjødt K, Palaniyar N, Steinhilber W, McCormack FX, Holmskov U.

Scand J Immunol. 2006 Aug;64(2):104-16.


Identification and characterization of porcine mannan-binding lectin A (pMBL-A), and determination of serum concentration heritability.

Juul-Madsen HR, Krogh-Meibom T, Henryon M, Palaniyar N, Heegaard PM, Purup S, Willis AC, Tornøe I, Ingvartsen KL, Hansen S, Holmskov U.

Immunogenetics. 2006 Apr;58(2-3):129-37. Epub 2006 Mar 4.


Surfactant protein D is proatherogenic in mice.

Sorensen GL, Madsen J, Kejling K, Tornoe I, Nielsen O, Townsend P, Poulain F, Nielsen CH, Reid KB, Hawgood S, Falk E, Holmskov U.

Am J Physiol Heart Circ Physiol. 2006 Jun;290(6):H2286-94. Epub 2005 Dec 30.


Surfactant protein D binds to human immunodeficiency virus (HIV) envelope protein gp120 and inhibits HIV replication.

Meschi J, Crouch EC, Skolnik P, Yahya K, Holmskov U, Leth-Larsen R, Tornoe I, Tecle T, White MR, Hartshorn KL.

J Gen Virol. 2005 Nov;86(Pt 11):3097-107.


A common polymorphism in the SFTPD gene influences assembly, function, and concentration of surfactant protein D.

Leth-Larsen R, Garred P, Jensenius H, Meschi J, Hartshorn K, Madsen J, Tornoe I, Madsen HO, Sørensen G, Crouch E, Holmskov U.

J Immunol. 2005 Feb 1;174(3):1532-8.


Cooperative anti-influenza activities of respiratory innate immune proteins and neuraminidase inhibitor.

White MR, Crouch E, van Eijk M, Hartshorn M, Pemberton L, Tornoe I, Holmskov U, Hartshorn KL.

Am J Physiol Lung Cell Mol Physiol. 2005 May;288(5):L831-40. Epub 2004 Dec 17.


CRP-ductin, the mouse homologue of gp-340/deleted in malignant brain tumors 1 (DMBT1), binds gram-positive and gram-negative bacteria and interacts with lung surfactant protein D.

Madsen J, Tornøe I, Nielsen O, Lausen M, Krebs I, Mollenhauer J, Kollender G, Poustka A, Skjødt K, Holmskov U.

Eur J Immunol. 2003 Aug;33(8):2327-36.


Surfactant protein D (SP-D) serum levels in patients with community-acquired pneumonia.

Leth-Larsen R, Nordenbaek C, Tornoe I, Moeller V, Schlosser A, Koch C, Teisner B, Junker P, Holmskov U.

Clin Immunol. 2003 Jul;108(1):29-37.


Expression and localization of lung surfactant protein A in human tissues.

Madsen J, Tornoe I, Nielsen O, Koch C, Steinhilber W, Holmskov U.

Am J Respir Cell Mol Biol. 2003 Nov;29(5):591-7. Epub 2003 May 30.


The scavenger receptor, cysteine-rich domain-containing molecule gp-340 is differentially regulated in epithelial cell lines by phorbol ester.

Kang W, Nielsen O, Fenger C, Madsen J, Hansen S, Tornoe I, Eggleton P, Reid KB, Holmskov U.

Clin Exp Immunol. 2002 Dec;130(3):449-58.


Human salivary agglutinin binds to lung surfactant protein-D and is identical with scavenger receptor protein gp-340.

Ligtenberg TJ, Bikker FJ, Groenink J, Tornoe I, Leth-Larsen R, Veerman EC, Nieuw Amerongen AV, Holmskov U.

Biochem J. 2001 Oct 1;359(Pt 1):243-8.


Localization of lung surfactant protein D on mucosal surfaces in human tissues.

Madsen J, Kliem A, Tornoe I, Skjodt K, Koch C, Holmskov U.

J Immunol. 2000 Jun 1;164(11):5866-70.


Microfibril-associated protein 4 is present in lung washings and binds to the collagen region of lung surfactant protein D.

Lausen M, Lynch N, Schlosser A, Tornoe I, Saekmose SG, Teisner B, Willis AC, Crouch E, Schwaeble W, Holmskov U.

J Biol Chem. 1999 Nov 5;274(45):32234-40.


Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D.

Holmskov U, Mollenhauer J, Madsen J, Vitved L, Gronlund J, Tornoe I, Kliem A, Reid KB, Poustka A, Skjodt K.

Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10794-9.


The plasma levels of coglutinin are heritable in cattle and low levels predispose to infection.

Holmskov U, Jensenius JC, Tornøe I, Løvendahl P.

Immunology. 1998 Mar;93(3):431-6.


Pilot scale purification of human monoclonal IgM (COU-1) for clinical trials.

Tornøe I, Titlestad IL, Kejling K, Erb K, Ditzel HJ, Jensenius JC.

J Immunol Methods. 1997 Jun 23;205(1):11-7.


Isolation and characterization of a new member of the scavenger receptor superfamily, glycoprotein-340 (gp-340), as a lung surfactant protein-D binding molecule.

Holmskov U, Lawson P, Teisner B, Tornoe I, Willis AC, Morgan C, Koch C, Reid KB.

J Biol Chem. 1997 May 23;272(21):13743-9.


Comparative study of the structural and functional properties of a bovine plasma C-type lectin, collectin-43, with other collectins.

Holmskov U, Laursen SB, Malhotra R, Wiedemann H, Timpl R, Stuart GR, Tornøe I, Madsen PS, Reid KB, Jensenius JC.

Biochem J. 1995 Feb 1;305 ( Pt 3):889-96.

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