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Items: 40

1.

A phase 1/2 study of orally administered synthetic hypericin for treatment of recurrent malignant gliomas.

Couldwell WT, Surnock AA, Tobia AJ, Cabana BE, Stillerman CB, Forsyth PA, Appley AJ, Spence AM, Hinton DR, Chen TC.

Cancer. 2011 Nov 1;117(21):4905-15. doi: 10.1002/cncr.26123. Epub 2011 Mar 31.

2.

Modeling cholinesterase activity for human dietary risk assessment of carbamate insecticides.

Williams RL, Mihlan GJ, Tobia AJ.

Risk Anal. 2008 Aug;28(4):1069-79. doi: 10.1111/j.1539-6924.2008.01088.x. Epub 2008 Jul 9.

PMID:
18631301
3.

In vitro and in vivo antibacterial activities of levofloxacin (l-ofloxacin), an optically active ofloxacin.

Fu KP, Lafredo SC, Foleno B, Isaacson DM, Barrett JF, Tobia AJ, Rosenthale ME.

Antimicrob Agents Chemother. 1992 Apr;36(4):860-6. Erratum in: Antimicrob Agents Chemother 1992 Aug;36(8):1797.

4.

Bemoradan--a novel inhibitor of the rolipram-insensitive cyclic AMP phosphodiesterase from canine heart tissue.

Moore JB Jr, Combs DW, Tobia AJ.

Biochem Pharmacol. 1991 Jul 15;42(3):679-83.

PMID:
1650219
5.

In-vivo evaluation of ofloxacin in Salmonella typhimurium infection in mice.

Fu KP, Hilliard J, Isaacson D, Tobia AJ, Rosenthale ME, McGuire JL.

J Antimicrob Chemother. 1990 Feb;25(2):263-8. Erratum in: J Antimicrob Chemother 1990 May;25(5):886.

PMID:
2184159
6.

6-Benzoxazinylpyridazin-3-ones: potent, long-acting positive inotrope and peripheral vasodilator agents.

Combs DW, Rampulla MS, Bell SC, Klaubert DH, Tobia AJ, Falotico R, Haertlein B, Lakas-Weiss C, Moore JB.

J Med Chem. 1990 Jan;33(1):380-6.

PMID:
2153210
7.

Positive inotropic and hemodynamic properties of flosequinan, a new vasodilator, and a sulfone metabolite.

Falotico R, Haertlein BJ, Lakas-Weiss CS, Salata JJ, Tobia AJ.

J Cardiovasc Pharmacol. 1989 Sep;14(3):412-8.

PMID:
2476620
8.

Renal vasodilators. The role of the 4-substituent in isoquinolin-3-ol cardiovascular agents: 4-ureido derivatives of isoquinolin-3-ol with selective renal vasodilator properties.

Kanojia RM, Lever OW Jr, Press JB, Williams L, Werblood HM, Giardino EC, Falotico R, Tobia AJ.

J Med Chem. 1989 May;32(5):990-7.

PMID:
2709385
9.

Cardiotonic agents. Synthesis and inotropic activity of a series of isoquinolin-3-ol derivatives.

Kanojia RM, Press JB, Lever OW Jr, Williams L, McNally JJ, Tobia AJ, Falotico R, Moore JB Jr.

J Med Chem. 1988 Jul;31(7):1363-8.

PMID:
3385731
10.

Selective inhibition of 14 alpha-desmethyl sterol synthesis in Candida albicans by terconazole, a new triazole antimycotic.

Isaacson DM, Tolman EL, Tobia AJ, Rosenthale ME, McGuire JL, Vanden Bossche H, Janssen PA.

J Antimicrob Chemother. 1988 Mar;21(3):333-43.

PMID:
3129389
11.

Selective gastric antilesion properties of rioprostil, a prostaglandin E1 analog, in rats and dogs.

Katz LB, Shriver DA, Tobia AJ, Rosenthale ME.

J Pharmacol Exp Ther. 1987 Sep;242(3):927-33.

PMID:
3116199
12.
13.
14.

The effects of the quinone type drugs on hydroxyl radical (OH.) production by rat liver microsomes.

Tobia AJ, Couri D, Sagone A.

J Toxicol Environ Health. 1985;15(2):265-77.

PMID:
3925152
15.

Altered regional vasodilator responses to glossopharyngeal nerve stimulation in spontaneously hypertensive rats.

Lee JY, Walsh GM, Mokler CM, Tobia AJ.

J Hypertens. 1984 Oct;2(5):493-9.

PMID:
6530553
16.

Antifertility activity and general pharmacological properties of ORF 13811: a synthetic analog of zoapatanol.

Hahn DW, Tobia AJ, Rosenthale ME, McGuire JL.

Contraception. 1984 Jul;30(1):39-53.

PMID:
6434229
17.

Dopaminergic activity of substituted 6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines.

Pfeiffer FR, Wilson JW, Weinstock J, Kuo GY, Chambers PA, Holden KG, Hahn RA, Wardell JR Jr, Tobia AJ, Setler PE, Sarau HM.

J Med Chem. 1982 Apr;25(4):352-8.

PMID:
7069713
18.

Vascular pressure-flow analysis in normal and hypoxemic spontaneously hypertensive rats.

Walsh GM, Tobia AJ.

Clin Exp Hypertens A. 1982;4(3):445-60.

PMID:
7074997
19.

Renal vasodilator responses to captopril in dogs pretreated with indomethacin.

Tobia AJ, Giardino EC.

Proc Soc Exp Biol Med. 1981 Jun;167(2):242-7. No abstract available.

PMID:
7232430
20.

Unaltered maximum reflex vasodilatory capacity of the perfused hindquarters of spontaneously hypertensive rats.

Lee JY, Walsh GM, Mokler CM, Tobia AJ.

Clin Exp Hypertens. 1981;3(5):1019-38.

PMID:
6793334
21.

Reflex cardiovascular responses induced by electrical stimulation of glossopharyngeal nerves in the rat.

Lee JY, Walsh GM, Mokler CM, Tobia AJ.

J Pharmacol Methods. 1981 Jan;5(1):15-27.

PMID:
6115100
22.

Separation of potent central and renal dopamine agonist activity in substituted 6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepines.

Weinstock J, Wilson JW, Ladd DL, Brush CK, Pfeiffer FR, Kuo GY, Holden KG, Yim NC, Hahn RA, Wardell JR Jr, Tobia AJ, Setler PE, Sarau HM, Ridley PT.

J Med Chem. 1980 Sep;23(9):973-5. No abstract available.

PMID:
7411552
23.

Altered cardiovascular responses to glossopharyngeal nerve stimulation in the spontaneously hypertensive rat.

Lee JY, Walsh GM, Mokler CM, Tobia AJ.

Res Commun Chem Pathol Pharmacol. 1980 Jul;29(1):27-42.

PMID:
7403677
24.

Intact hindquarter vascular responses of young spontaneously hypertensive rats to norepinephrine and tyramine.

Lee JY, Walsh GM, Tobia AJ.

Life Sci. 1980 Jun 2;26(22):1877-83. No abstract available.

PMID:
7401905
25.

Labetalol binding to specific alpha- and beta-adrenergic sites in vitro and its antagonism of adrenergic responses in vivo.

Greenslade FC, Tobia AJ, Madison SM, Krider KM, Newquist KL.

J Mol Cell Cardiol. 1979 Aug;11(8):803-11. No abstract available.

PMID:
226721
26.

Interaction of prazosin with alpha-adrenergic receptors--in vitro binding and in vivo antagonism.

Greenslade FC, Scott CK, Chasin M, Madison SM, Tobia AJ.

Biochem Pharmacol. 1979 Aug 1;28(15):2409-11. No abstract available.

PMID:
40559
27.

Altered hemodynamic responses to acute hypoxemia in spontaneously hypertensive rats.

Walsh GM, Tsuchiya M, Cox AC, Tobia AJ, Frohlich ED.

Am J Physiol. 1978 Mar;234(3):H275-9.

PMID:
24350
28.

An autoperfusion technique for nonsteady-state vascular pressure-flow analysis in the rat.

Walsh GM, Tobia AJ, Frohlich ED.

Cardiovasc Res. 1977 Sep;11(5):434-9.

PMID:
589634
29.

Regional blood flow and vascular resistance in the spontaneously hypertensive rat.

Tobia AJ, Lee JY, Walsh GM.

Cardiovasc Res. 1974 Nov;8(6):758-62. No abstract available.

PMID:
4457223
30.

Normal cardiac output in the conscious young spontaneously hypertensive rat: evidence for higher oxygen utilization.

Tadepalli AS, Walsh GM, Tobia AJ.

Life Sci. 1974 Sep 15;15(6):1103-14. No abstract available.

PMID:
4549955
31.

Intrinsic left ventricular performance in the young spontaneously hypertensive rat.

Walsh GM, Tobia AJ.

Res Commun Chem Pathol Pharmacol. 1974 Aug;8(4):623-33. No abstract available.

PMID:
4421388
32.

Hemodynamic alterations in the young spontaneously hypertensive rat: elevated total systemic and hindquarter vascular resistance.

Tobia AJ, Walsh GM, Lee JY.

Proc Soc Exp Biol Med. 1974 Jul;146(3):670-3. No abstract available.

PMID:
4842267
33.

The role of demethylbetahistine in the depressor response to betahistine in the rat.

Tobia AJ, Sternson LA, Walsh GM, LaRocca JP.

Proc Soc Exp Biol Med. 1974 Mar;145(3):778-81. No abstract available.

PMID:
4206516
34.

The metabolism of betahistine in the rat.

Sternson LA, Tobia AJ, Walsh GM, Sternson AW.

Drug Metab Dispos. 1974 Mar-Apr;2(2):123-8. No abstract available.

PMID:
4150992
35.
36.

In vivo ventricular responses to mechanical afterloading in the chordotomized rat.

Walsh GM, Tobia AJ, Sternson LA.

J Appl Physiol. 1973 Dec;35(6):936-9. No abstract available.

PMID:
4520142
37.

Electromagnetic measurement of iliac artery blood flow in the rat: on-line integration of flow.

Evans RH, Tobia AJ.

Cardiovasc Res. 1973 Jan;7(1):1-5. No abstract available.

PMID:
4348604
38.

Drug-induced modification of ( 3 H)-histamine catabolism in the rat hypothalamus in vivo.

Akin FJ, Tobia AJ.

Res Commun Chem Pathol Pharmacol. 1972 Jan;3(1):15-28. No abstract available.

PMID:
4555454
39.

Altered reflex vasodilatation in the hypertensive rat: possible role of histamine.

Tobia AJ, Adams MD, Miya TS, Bousquet WF.

J Pharmacol Exp Ther. 1970 Dec;175(3):619-26. No abstract available.

PMID:
4992408
40.

Histamine and reflex vasodilatation in the rat.

Tobia AJ, Adams MD, Miya TS, Bousquet WF.

Life Sci. 1969 Jul 1;8(13):745-50. No abstract available.

PMID:
4979525

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