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Optimizing responses to drug safety signals in pregnancy: the example of dolutegravir and neural tube defects.

Mofenson LM, Pozniak AL, Wambui J, Raizes E, Ciaranello A, Clayden P, Ehrenkranz P, Fakoya A, Hill A, Khoo S, Mahaka I, Modi S, Moore C, Phillips A, Siberry G, Sikwese K, Thorne C, Watts HD, Doherty M, Ford NP.

J Int AIDS Soc. 2019 Jul;22(7):e25352. doi: 10.1002/jia2.25352.


Height and timing of growth spurt during puberty in young people living with vertically acquired HIV in Europe and Thailand.

Crichton S, Belfrage E, Collins IJ, Doerholt K, Judd A, Le Coeur S, Spoulou V, Scherpbier H, Smit C, Goetghebuer T, Gibb DM, Noguera-Julian A, Navarro ML, Ramos JT, Galli L, Giaquinto C, Thorne C, Ansone S, Marczynska M, Okhonskaia L, Tejada BM, Jourdain G, Decker L, Ene L, Goodall R; Group authorship: The European Pregnancy and Paediatric HIV Cohort Collaboration (EPPICC) study group.

AIDS. 2019 Jul 9. doi: 10.1097/QAD.0000000000002294. [Epub ahead of print]


Single-Cell Analyses Confirm the Critical Role of LRP6 for Wnt Signaling in APC-Deficient Cells.

Cabel CR, Alizadeh E, Robbins DJ, Ahmed Y, Lee E, Thorne CA.

Dev Cell. 2019 Jun 17;49(6):827-828. doi: 10.1016/j.devcel.2019.05.039. No abstract available.


Encounters with Rheumatologists in a Publicly-Funded Canadian Healthcare System: A Population-Based Study.

Widdifield J, Bernatsky S, Pope JE, Ahluwalia V, Barber CEH, Eder L, Kuriya B, Ling V, Paterson JM, Thorne C.

J Rheumatol. 2019 Jun 15. pii: jrheum.190034. doi: 10.3899/jrheum.190034. [Epub ahead of print]


Stillbirth in women living with HIV delivering in the UK and Ireland: 2007-2015.

Favarato G, Townsend CL, Peters H, Sconza R, Bailey H, Borja MC, Tookey P, Thorne C.

J Acquir Immune Defic Syndr. 2019 May 29. doi: 10.1097/QAI.0000000000002087. [Epub ahead of print]


Young people in HIV care in Ukraine: a national survey on characteristics and service provision.

Kyselyova G, Martsynovska V, Volokha A, Nizova N, Malyuta R, Judd A, Thorne C, Bailey H.

Version 2. F1000Res. 2019 Mar 22 [revised 2019 Jan 1];8:323. doi: 10.12688/f1000research.18573.2. eCollection 2019.


Treatment strategies in early rheumatoid arthritis methotrexate management: Results from a prospective cohort.

Moura CS, Schieir O, Valois MF, Thorne C, Bartlett SJ, Pope JE, Hitchon CA, Boire G, Haraoui B, Hazlewood GS, Keystone EC, Tin D, Bykerk VP, Bernatsky S; Canadian Early Arthritis Cohort (CATCH) Investigators.

Arthritis Care Res (Hoboken). 2019 May 21. doi: 10.1002/acr.23927. [Epub ahead of print]


The challenge of the laboratory diagnosis in a confirmed congenital Zika virus syndrome in utero: A case report.

Sulleiro E, Frick MA, Rodó C, Espasa M, Thorne C, Espiau M, Martín-Nalda A, Suy A, Giaquinto C, Melendo S, Rando A, Alarcón A, Martinón-Torres F, Pumarola T, Soler-Palacín P, Soriano-Arandes A.

Medicine (Baltimore). 2019 May;98(20):e15532. doi: 10.1097/MD.0000000000015532.


Impact of residential area on the management of rheumatoid arthritis patients initiating their first biologic DMARD: Results from the Ontario Best Practices Research Initiative (OBRI).

Movahedi M, Joshi R, Rampakakis E, Thorne C, Cesta A, Sampalis JS, Bombardier C; Other OBRI Investigators.

Medicine (Baltimore). 2019 May;98(20):e15517. doi: 10.1097/MD.0000000000015517.


Hepatitis B virus infection in children and adolescents.

Indolfi G, Easterbrook P, Dusheiko G, Siberry G, Chang MH, Thorne C, Bulterys M, Chan PL, El-Sayed MH, Giaquinto C, Jonas MM, Meyers T, Walsh N, Wirth S, Penazzato M.

Lancet Gastroenterol Hepatol. 2019 Jun;4(6):466-476. doi: 10.1016/S2468-1253(19)30042-1. Epub 2019 Apr 11. Review.


Hepatitis C virus infection in children and adolescents.

Indolfi G, Easterbrook P, Dusheiko G, El-Sayed MH, Jonas MM, Thorne C, Bulterys M, Siberry G, Walsh N, Chang MH, Meyers T, Giaquinto C, Wirth S, Chan PL, Penazzato M.

Lancet Gastroenterol Hepatol. 2019 Jun;4(6):477-487. doi: 10.1016/S2468-1253(19)30046-9. Epub 2019 Apr 11. Review.


Treatment and monitoring of children with chronic hepatitis C in the Pre-DAA era: A European survey of 38 paediatric specialists.

Indolfi G, Bailey H, Serranti D, Giaquinto C, Thorne C; PENTAHep Study Group.

J Viral Hepat. 2019 Aug;26(8):961-968. doi: 10.1111/jvh.13111. Epub 2019 May 16.


Pregnancy and Neonatal Outcomes Following Prenatal Exposure to Dolutegravir.

Vannappagari V, Thorne C; for APR and EPPICC.

J Acquir Immune Defic Syndr. 2019 Aug 1;81(4):371-378. doi: 10.1097/QAI.0000000000002035.


Advanced liver disease in Russian children and adolescents with chronic hepatitis C.

Turkova A, Volynets GV, Crichton S, Skvortsova TA, Panfilova VN, Rogozina NV, Khavkin AI, Tumanova EL, Indolfi G, Thorne C.

J Viral Hepat. 2019 Jul;26(7):881-892. doi: 10.1111/jvh.13093. Epub 2019 Apr 7.


Anxiety symptoms and felt stigma among young people living with perinatally or behaviourally-acquired HIV in Ukraine: A cross-sectional survey.

Durteste M, Kyselyova G, Volokha A, Judd A, Thorne C, Cortina-Borja M, Malyuta R, Martsynovska V, Nizova N, Bailey H; Study of Young People Living with HIV in Ukraine.

PLoS One. 2019 Jan 24;14(1):e0210412. doi: 10.1371/journal.pone.0210412. eCollection 2019.


Investigating sirukumab for rheumatoid arthritis: 2-year results from the phase III SIRROUND-D study.

Thorne C, Takeuchi T, Karpouzas GA, Sheng S, Kurrasch R, Fei K, Hsu B.

RMD Open. 2018 Nov 16;4(2):e000731. doi: 10.1136/rmdopen-2018-000731. eCollection 2018.


Brief Report: Surveillance of Congenital Anomalies After Exposure to Raltegravir or Elvitegravir During Pregnancy in the United Kingdom and Ireland, 2008-2018.

Rasi V, Cortina-Borja M, Peters H, Sconza R, Thorne C.

J Acquir Immune Defic Syndr. 2019 Mar 1;80(3):264-268. doi: 10.1097/QAI.0000000000001924.


Commentary on: Why Should Young Aesthetic Plastic Surgeons Care About Aesthetic Medicine?

Thorne CH.

Aesthet Surg J. 2019 Jun 21;39(7):811-812. doi: 10.1093/asj/sjy299. No abstract available.


ACPA and RF as predictors of sustained clinical remission in patients with rheumatoid arthritis: data from the Ontario Best practices Research Initiative (OBRI).

Pope JE, Movahedi M, Rampakakis E, Cesta A, Sampalis JS, Keystone E, Thorne C, Bombardier C.

RMD Open. 2018 Nov 5;4(2):e000738. doi: 10.1136/rmdopen-2018-000738. eCollection 2018.


The Public Face of Rhinoplasty: Impact on Perceived Attractiveness and Personality.

Lu SM, Hsu DT, Perry AD, Leipziger LS, Kasabian AK, Bartlett SP, Thorne CH, Broer PN, Tanna N.

Plast Reconstr Surg. 2018 Oct;142(4):881-887. doi: 10.1097/PRS.0000000000004731.


Longitudinal and Reciprocal Relationships Between Psychological Well-Being and Smoking.

Lappan S, Thorne CB, Long D, Hendricks PS.

Nicotine Tob Res. 2018 Sep 14. doi: 10.1093/ntr/nty185. [Epub ahead of print]


One In Five Fewer Heart Attacks: Impact, Savings, And Sustainability In San Diego County Collaborative.

Fremont A, Kim AY, Bailey K, Hanley HR, Thorne C, Dudl RJ, Kaplan RM, Shortell SM, DeMaria AN.

Health Aff (Millwood). 2018 Sep;37(9):1457-1465. doi: 10.1377/hlthaff.2018.0443.


Microbial Sensing by Intestinal Myeloid Cells Controls Carcinogenesis and Epithelial Differentiation.

Miyata N, Morris LL, Chen Q, Thorne C, Singla A, Zhu W, Winter M, Melton SD, Li H, Sifuentes-Dominguez L, Llano E, Huff-Hardy K, Starokadomskyy P, Lopez A, Reese TA, Turer E, Billadeau DD, Winter SE, Burstein E.

Cell Rep. 2018 Aug 28;24(9):2342-2355. doi: 10.1016/j.celrep.2018.07.066.


Factors Influencing Patient Satisfaction in Plastic Surgery: A Nationwide Analysis.

Chen K, Congiusta S, Nash IS, Coppa GF, Smith ML, Kasabian AK, Thorne C, Tanna N.

Plast Reconstr Surg. 2018 Sep;142(3):820-825. doi: 10.1097/PRS.0000000000004658.


Cervical Branch of Facial Nerve: An Explanation for Recurrent Platysma Bands Following Necklift and Platysmaplasty.

Sinno S, Thorne CH.

Aesthet Surg J. 2019 Jan 1;39(1):1-7. doi: 10.1093/asj/sjy150.


HIV treatment in pregnancy.

Bailey H, Zash R, Rasi V, Thorne C.

Lancet HIV. 2018 Aug;5(8):e457-e467. doi: 10.1016/S2352-3018(18)30059-6. Epub 2018 Jun 26. Review.


The Scleroderma Patient-Centered Intervention Network Cohort: baseline clinical features and comparison with other large scleroderma cohorts.

Dougherty DH, Kwakkenbos L, Carrier ME, Salazar G, Assassi S, Baron M, Bartlett SJ, Furst DE, Gottesman K, van den Hoogen F, Malcarne VL, Mouthon L, Nielson WR, Poiraudeau S, Sauvé M, Boire G, Bruns A, Chung L, Denton C, Dunne JV, Fortin P, Frech T, Gill A, Gordon J, Herrick AL, Hinchcliff M, Hudson M, Johnson SR, Jones N, Kafaja S, Larché M, Manning J, Pope J, Spiera R, Steen V, Sutton E, Thorne C, Wilcox P, Thombs BD, Mayes MD; SPIN Investigators.

Rheumatology (Oxford). 2018 Sep 1;57(9):1623-1631. doi: 10.1093/rheumatology/key139.


Safety and pharmacokinetics of dolutegravir in HIV-positive pregnant women: a systematic review.

Hill A, Clayden P, Thorne C, Christie R, Zash R.

J Virus Erad. 2018 Apr 1;4(2):66-71.


Impact of the Adalimumab Patient Support Program on Clinical Outcomes in Ankylosing Spondylitis: Results from the COMPANION Study.

Bessette L, Lebovic G, Millson B, Charland K, Donepudi K, Gaetano T, Remple V, Latour MG, Gazel S, Laliberté MC, Thorne C.

Rheumatol Ther. 2018 Jun;5(1):75-85. doi: 10.1007/s40744-018-0109-3. Epub 2018 Apr 9.


Impact of the Adalimumab Patient Support Program's Care Coach Calls on Persistence and Adherence in Canada: An Observational Retrospective Cohort Study.

Marshall JK, Bessette L, Thorne C, Shear NH, Lebovic G, Gerega SK, Millson B, Oraichi D, Gaetano T, Gazel S, Latour MG, Laliberté MC.

Clin Ther. 2018 Mar;40(3):415-429.e6. doi: 10.1016/j.clinthera.2018.02.001. Epub 2018 Mar 6.


Enteroid Monolayers Reveal an Autonomous WNT and BMP Circuit Controlling Intestinal Epithelial Growth and Organization.

Thorne CA, Chen IW, Sanman LE, Cobb MH, Wu LF, Altschuler SJ.

Dev Cell. 2018 Mar 12;44(5):624-633.e4. doi: 10.1016/j.devcel.2018.01.024. Epub 2018 Mar 1.


The epidemiology of adolescents living with perinatally acquired HIV: A cross-region global cohort analysis.

Collaborative Initiative for Paediatric HIV Education and Research (CIPHER) Global Cohort Collaboration, Slogrove AL, Schomaker M, Davies MA, Williams P, Balkan S, Ben-Farhat J, Calles N, Chokephaibulkit K, Duff C, Eboua TF, Kekitiinwa-Rukyalekere A, Maxwell N, Pinto J, Seage G 3rd, Teasdale CA, Wanless S, Warszawski J, Wools-Kaloustian K, Yotebieng M, Timmerman V, Collins IJ, Goodall R, Smith C, Patel K, Paul M, Gibb D, Vreeman R, Abrams EJ, Hazra R, Van Dyke R, Bekker LG, Mofenson L, Vicari M, Essajee S, Penazzato M, Anabwani G, Q Mohapi E, N Kazembe P, Hlatshwayo M, Lumumba M, Goetghebuer T, Thorne C, Galli L, van Rossum A, Giaquinto C, Marczynska M, Marques L, Prata F, Ene L, Okhonskaia L, Rojo P, Fortuny C, Naver L, Rudin C, Le Coeur S, Volokha A, Rouzier V, Succi R, Sohn A, Kariminia A, Edmonds A, Lelo P, Ayaya S, Ongwen P, Jefferys LF, Phiri S, Mubiana-Mbewe M, Sawry S, Renner L, Sylla M, Abzug MJ, Levin M, Oleske J, Chernoff M, Traite S, Purswani M, Chadwick EG, Judd A, Leroy V.

PLoS Med. 2018 Mar 1;15(3):e1002514. doi: 10.1371/journal.pmed.1002514. eCollection 2018 Mar.


Routine Pathologic Evaluation of Plastic Surgery Specimens: Are We Wasting Time and Money?

Fisher M, Alba B, Bhuiya T, Kasabian AK, Thorne CH, Tanna N.

Plast Reconstr Surg. 2018 Mar;141(3):812-816. doi: 10.1097/PRS.0000000000004129.


Preterm delivery and small-for-gestation outcomes in HIV-infected pregnant women on antiretroviral therapy in rural South Africa: Results from a cohort study, 2010-2015.

Chetty T, Thorne C, Coutsoudis A.

PLoS One. 2018 Feb 22;13(2):e0192805. doi: 10.1371/journal.pone.0192805. eCollection 2018.


Long-term trends in mortality and AIDS-defining events after combination ART initiation among children and adolescents with perinatal HIV infection in 17 middle- and high-income countries in Europe and Thailand: A cohort study.

European Pregnancy and Paediatric HIV Cohort Collaboration (EPPICC) study group in EuroCoord, Judd A, Chappell E, Turkova A, Le Coeur S, Noguera-Julian A, Goetghebuer T, Doerholt K, Galli L, Pajkrt D, Marques L, Collins IJ, Gibb DM, González Tome MI, Navarro M, Warszawski J, Königs C, Spoulou V, Prata F, Chiappini E, Naver L, Giaquinto C, Thorne C, Marczynska M, Okhonskaia L, Posfay-Barbe K, Ounchanum P, Techakunakorn P, Kiseleva G, Malyuta R, Volokha A, Ene L, Goodall R.

PLoS Med. 2018 Jan 30;15(1):e1002491. doi: 10.1371/journal.pmed.1002491. eCollection 2018 Jan.


National audit of perinatal HIV infections in the UK, 2006-2013: what lessons can be learnt?

Peters H, Thorne C, Tookey PA, Byrne L.

HIV Med. 2018 Apr;19(4):280-289. doi: 10.1111/hiv.12577. Epub 2018 Jan 16.


Dose Escalation and Co-therapy Intensification Between Etanercept, Adalimumab, and Infliximab: The CADURA Study.

Thorne C, Boire G, Chow A, Garces K, Liu F, Poulin-Costello M, Walker V, Haraoui B.

Open Rheumatol J. 2017 Oct 24;11:123-135. doi: 10.2174/1874312901711010123. eCollection 2017.


Protease inhibitors and preterm delivery: another piece in the puzzle.

Favarato G, Townsend CL, Bailey H, Peters H, Tookey PA, Taylor GP, Thorne C.

AIDS. 2018 Jan 14;32(2):243-252. doi: 10.1097/QAD.0000000000001694.


Viraemia before, during and after pregnancy in HIV-infected women on antiretroviral therapy in rural KwaZulu-Natal, South Africa, 2010-2015.

Chetty T, Newell ML, Thorne C, Coutsoudis A.

Trop Med Int Health. 2018 Jan;23(1):79-91. doi: 10.1111/tmi.13001. Epub 2017 Nov 28.


Sirukumab for rheumatoid arthritis: the phase III SIRROUND-D study.

Takeuchi T, Thorne C, Karpouzas G, Sheng S, Xu W, Rao R, Fei K, Hsu B, Tak PP.

Ann Rheum Dis. 2017 Dec;76(12):2001-2008. doi: 10.1136/annrheumdis-2017-211328. Epub 2017 Aug 30.


Incident HIV during pregnancy and early postpartum period: a population-based cohort study in a rural area in KwaZulu-Natal, South Africa.

Chetty T, Vandormael A, Thorne C, Coutsoudis A.

BMC Pregnancy Childbirth. 2017 Jul 26;17(1):248. doi: 10.1186/s12884-017-1421-6.


Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors.

Li B, Orton D, Neitzel LR, Astudillo L, Shen C, Long J, Chen X, Kirkbride KC, Doundoulakis T, Guerra ML, Zaias J, Fei DL, Rodriguez-Blanco J, Thorne C, Wang Z, Jin K, Nguyen DM, Sands LR, Marchetti F, Abreu MT, Cobb MH, Capobianco AJ, Lee E, Robbins DJ.

Sci Signal. 2017 Jun 27;10(485). pii: eaak9916. doi: 10.1126/scisignal.aak9916.


Pregnancy incidence and outcomes in women with perinatal HIV infection.

Byrne L, Sconza R, Foster C, Tookey PA, Cortina-Borja M, Thorne C.

AIDS. 2017 Jul 31;31(12):1745-1754. doi: 10.1097/QAD.0000000000001552.


A restatement of the natural science evidence concerning catchment-based 'natural' flood management in the UK.

Dadson SJ, Hall JW, Murgatroyd A, Acreman M, Bates P, Beven K, Heathwaite L, Holden J, Holman IP, Lane SN, O'Connell E, Penning-Rowsell E, Reynard N, Sear D, Thorne C, Wilby R.

Proc Math Phys Eng Sci. 2017 Mar;473(2199):20160706. doi: 10.1098/rspa.2016.0706. Epub 2017 Mar 15. Review.


Modelling CD4 T Cell Recovery in Hepatitis C and HIV Co-infected Children Receiving Antiretroviral Therapy.

Majekodunmi AO, Thorne C, Malyuta R, Volokha A, Callard RE, Klein NJ, Lewis J; European Paediatric HIV/HCV Co-infection Study group in the European Pregnancy and Paediatric HIV Cohort Collaboration and the Ukraine Paediatric HIV Cohort Study in EuroCoord.

Pediatr Infect Dis J. 2017 May;36(5):e123-e129. doi: 10.1097/INF.0000000000001478.


The Challenge of Treating Children With Hepatitis C Virus Infection.

Indolfi G, Thorne C, El Sayed MH, Giaquinto C, Gonzalez-Peralta RP.

J Pediatr Gastroenterol Nutr. 2017 Jun;64(6):851-854. doi: 10.1097/MPG.0000000000001589. Review.


e-Learning in Advanced Life Support-What factors influence assessment outcome?

Thorne CJ, Lockey AS, Kimani PK, Bullock I, Hampshire S, Begum-Ali S, Perkins GD; Advanced Life Support Subcommittee of the Resuscitation Council (UK).

Resuscitation. 2017 May;114:83-91. doi: 10.1016/j.resuscitation.2017.02.014. Epub 2017 Feb 24.


The Relationships of Expectancies With E-cigarette Use Among Hospitalized Smokers: A Prospective Longitudinal Study.

Hendricks PS, Thorne CB, Lappan SN, Sweat NW, Cheong J, Ramachandran R, Kohler CL, Bailey WC, Harrington KF.

Nicotine Tob Res. 2018 Jan 5;20(2):224-230. doi: 10.1093/ntr/ntx043.


UK Mother-to-Child HIV Transmission Rates Continue to Decline: 2012-2014.

Peters H, Francis K, Sconza R, Horn A, S Peckham C, Tookey PA, Thorne C.

Clin Infect Dis. 2017 Feb 15;64(4):527-528. doi: 10.1093/cid/ciw791. No abstract available.


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