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Items: 1 to 50 of 362

1.

Hippocampal long-term potentiation is supported by presynaptic and postsynaptic tyrosine receptor kinase B-mediated phospholipase Cgamma signaling.

Gärtner A, Polnau DG, Staiger V, Sciarretta C, Minichiello L, Thoenen H, Bonhoeffer T, Korte M.

J Neurosci. 2006 Mar 29;26(13):3496-504.

2.

Induction of long-term potentiation and depression is reflected by corresponding changes in secretion of endogenous brain-derived neurotrophic factor.

Aicardi G, Argilli E, Cappello S, Santi S, Riccio M, Thoenen H, Canossa M.

Proc Natl Acad Sci U S A. 2004 Nov 2;101(44):15788-92. Epub 2004 Oct 25.

3.

Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches.

Thoenen H, Sendtner M.

Nat Neurosci. 2002 Nov;5 Suppl:1046-50. Review.

PMID:
12403983
5.

Neurotrophins and activity-dependent plasticity.

Thoenen H.

Prog Brain Res. 2000;128:183-91. Review. No abstract available.

PMID:
11105678
6.

Ultrastructural identification of storage compartments and localization of activity-dependent secretion of neurotrophin 6 in hippocampal neurons.

Gärtner A, Shostak Y, Hackel N, Ethell IM, Thoenen H.

Mol Cell Neurosci. 2000 Mar;15(3):215-34.

PMID:
10736200
7.

Neurotrophin-evoked rapid excitation through TrkB receptors.

Kafitz KW, Rose CR, Thoenen H, Konnerth A.

Nature. 1999 Oct 28;401(6756):918-21.

PMID:
10553907
8.

Are there differences between the secretion characteristics of NGF and BDNF? Implications for the modulatory role of neurotrophins in activity-dependent neuronal plasticity.

Griesbeck O, Canossa M, Campana G, Gärtner A, Hoener MC, Nawa H, Kolbeck R, Thoenen H.

Microsc Res Tech. 1999 May 15-Jun 1;45(4-5):262-75.

PMID:
10383119
9.

Retinal ganglion cell loss after the period of naturally occurring cell death in bcl-2-/- mice.

Cellerino A, Michaelidis T, Barski JJ, Bähr M, Thoenen H, Meyer M.

Neuroreport. 1999 Apr 6;10(5):1091-5.

PMID:
10321489
10.

A role for BDNF in mechanosensation.

Carroll P, Lewin GR, Koltzenburg M, Toyka KV, Thoenen H.

Nat Neurosci. 1998 May;1(1):42-6.

PMID:
10195107
11.

Calbindin-D28k fails to protect hippocampal neurons against ischemia in spite of its cytoplasmic calcium buffering properties: evidence from calbindin-D28k knockout mice.

Klapstein GJ, Vietla S, Lieberman DN, Gray PA, Airaksinen MS, Thoenen H, Meyer M, Mody I.

Neuroscience. 1998 Jul;85(2):361-73.

PMID:
9622236
12.

Post-occlusion treatment with BDNF reduces infarct size in a model of permanent occlusion of the middle cerebral artery in rat.

Yamashita K, Wiessner C, Lindholm D, Thoenen H, Hossmann KA.

Metab Brain Dis. 1997 Dec;12(4):271-80.

PMID:
9475500
13.

Neurotrophin release by neurotrophins: implications for activity-dependent neuronal plasticity.

Canossa M, Griesbeck O, Berninger B, Campana G, Kolbeck R, Thoenen H.

Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):13279-86.

14.

Endogenous ciliary neurotrophic factor is a lesion factor for axotomized motoneurons in adult mice.

Sendtner M, Götz R, Holtmann B, Thoenen H.

J Neurosci. 1997 Sep 15;17(18):6999-7006.

15.

Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin D28k gene.

Airaksinen MS, Eilers J, Garaschuk O, Thoenen H, Konnerth A, Meyer M.

Proc Natl Acad Sci U S A. 1997 Feb 18;94(4):1488-93.

16.

Rapid gene transfer into cultured hippocampal neurons and acute hippocampal slices using adenoviral vectors.

Griesbeck O, Korte M, Gravel C, Bonhoeffer T, Thoenen H.

Brain Res Mol Brain Res. 1997 Feb;44(1):171-7.

PMID:
9030715
17.

Reduced size of retinal ganglion cell axons and hypomyelination in mice lacking brain-derived neurotrophic factor.

Cellerino A, Carroll P, Thoenen H, Barde YA.

Mol Cell Neurosci. 1997;9(5-6):397-408.

PMID:
9361277
19.

Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice.

Korte M, Griesbeck O, Gravel C, Carroll P, Staiger V, Thoenen H, Bonhoeffer T.

Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12547-52.

20.

Introduction of the negative selection marker into replacement vectors by a single ligation step.

Tzimagiorgis G, Michaelidis TM, Lindholm D, Thoenen H.

Nucleic Acids Res. 1996 Sep 1;24(17):3476-7.

21.

Ciliary Neurotrophic Factor Enhances the Rate of Oligodendrocyte Generation

Barres BA, Burne JF, Holtmann B, Thoenen H, Sendtner M, Raff MC.

Mol Cell Neurosci. 1996 Aug;8(2/3):146-56.

PMID:
8954629
22.

Cell density increases Bcl-2 and Bcl-x expression in addition to survival of cultured cerebellar granule neurons.

Ohga Y, Zirrgiebel U, Hamnér S, Michaelidis TM, Cooper J, Thoenen H, Lindholm D.

Neuroscience. 1996 Aug;73(4):913-7.

PMID:
8809810
23.

Brain-derived neurotrophic factor reversed experience-dependent synaptic modifications in kitten visual cortex.

Galuske RA, Kim DS, Castren E, Thoenen H, Singer W.

Eur J Neurosci. 1996 Jul;8(7):1554-9.

PMID:
8758963
24.

Autocrine-paracrine regulation of hippocampal neuron survival by IGF-1 and the neurotrophins BDNF, NT-3 and NT-4.

Lindholm D, Carroll P, Tzimagiorgis G, Thoenen H.

Eur J Neurosci. 1996 Jul;8(7):1452-60.

PMID:
8758952
25.

Inactivation of bcl-2 results in progressive degeneration of motoneurons, sympathetic and sensory neurons during early postnatal development.

Michaelidis TM, Sendtner M, Cooper JD, Airaksinen MS, Holtmann B, Meyer M, Thoenen H.

Neuron. 1996 Jul;17(1):75-89.

26.

Cryptic physiological trophic support of motoneurons by LIF revealed by double gene targeting of CNTF and LIF.

Sendtner M, Götz R, Holtmann B, Escary JL, Masu Y, Carroll P, Wolf E, Brem G, Brület P, Thoenen H.

Curr Biol. 1996 Jun 1;6(6):686-94.

27.
29.

Specific subtypes of cutaneous mechanoreceptors require neurotrophin-3 following peripheral target innervation.

Airaksinen MS, Koltzenburg M, Lewin GR, Masu Y, Helbig C, Wolf E, Brem G, Toyka KV, Thoenen H, Meyer M.

Neuron. 1996 Feb;16(2):287-95.

30.
31.

Combination of gene targeting and gene transfer by adenoviral vectors in the analysis of neurotrophin-mediated neuronal plasticity.

Griesbeck O, Korte M, Staiger V, Gravel C, Carroll P, Bonhoeffer T, Thoenen H.

Cold Spring Harb Symp Quant Biol. 1996;61:77-83. Review. No abstract available.

PMID:
9246437
32.

The involvement of brain-derived neurotrophic factor in hippocampal long-term potentiation revealed by gene targeting experiments.

Korte M, Staiger V, Griesbeck O, Thoenen H, Bonhoeffer T.

J Physiol Paris. 1996;90(3-4):157-64.

PMID:
9116659
33.

Ciliary neurotrophic factor enhances the rate of oligodendrocyte generation.

Barres BA, Burne JF, Holtmann B, Thoenen H, Sendtner M, Raff MC.

Mol Cell Neurosci. 1996;8(2-3):146-56.

PMID:
8918831
34.

Characterization of TrkB receptor-mediated signaling pathways in rat cerebellar granule neurons: involvement of protein kinase C in neuronal survival.

Zirrgiebel U, Ohga Y, Carter B, Berninger B, Inagaki N, Thoenen H, Lindholm D.

J Neurochem. 1995 Nov;65(5):2241-50.

PMID:
7595513
35.

Gene transfer through the blood-nerve barrier: NGF-engineered neuritogenic T lymphocytes attenuate experimental autoimmune neuritis.

Kramer R, Zhang Y, Gehrmann J, Gold R, Thoenen H, Wekerle H.

Nat Med. 1995 Nov;1(11):1162-6.

PMID:
7584988
36.

Neurotrophins and neuronal plasticity.

Thoenen H.

Science. 1995 Oct 27;270(5236):593-8. Review.

PMID:
7570017
37.

Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor.

Korte M, Carroll P, Wolf E, Brem G, Thoenen H, Bonhoeffer T.

Proc Natl Acad Sci U S A. 1995 Sep 12;92(19):8856-60.

38.

Expression of neurotrophins in skeletal muscle: quantitative comparison and significance for motoneuron survival and maintenance of function.

Griesbeck O, Parsadanian AS, Sendtner M, Thoenen H.

J Neurosci Res. 1995 Sep 1;42(1):21-33.

PMID:
8531223
39.

GABAergic stimulation switches from enhancing to repressing BDNF expression in rat hippocampal neurons during maturation in vitro.

Berninger B, Marty S, Zafra F, da Penha Berzaghi M, Thoenen H, Lindholm D.

Development. 1995 Aug;121(8):2327-35.

41.

TrkA tyrosine residues involved in NGF-induced neurite outgrowth of PC12 cells.

Inagaki N, Thoenen H, Lindholm D.

Eur J Neurosci. 1995 Jun 1;7(6):1125-33.

PMID:
7582085
42.

Ciliary neurotrophic factor (CNTF): physiological and pharmacological effects.

Sendtner M, Hughes RA, Dittrich F, Holtmann B, Masu Y, Carroll P, Ochs G, Toyka KV, Thoenen H.

Restor Neurol Neurosci. 1995 Jan 1;8(1):95-6. doi: 10.3233/RNN-1995-81222. No abstract available.

PMID:
21551816
44.

Brain-derived neurotrophic factor and neurotrophin-4 increase neurotrophin-3 expression in the rat hippocampus.

Lindholm D, da Penha Berzaghi M, Cooper J, Thoenen H, Castrén E.

Int J Dev Neurosci. 1994 Dec;12(8):745-51.

PMID:
7747601
45.

Glucocorticoids and neurotrophin gene regulation in the nervous system.

Lindholm D, Castrén M, Hengerer B, Leingärtner A, Castrén E, Thoenen H.

Ann N Y Acad Sci. 1994 Nov 30;746:195-202; discussion 202-3. Review. No abstract available.

PMID:
7825876
46.

Neurotrophin-6 is a new member of the nerve growth factor family.

Götz R, Köster R, Winkler C, Raulf F, Lottspeich F, Schartl M, Thoenen H.

Nature. 1994 Nov 17;372(6503):266-9.

PMID:
7969471
47.

Neurodegenerative disease. Oxidative stress and motorneuron disease.

Sendtner M, Thoenen H.

Curr Biol. 1994 Nov 1;4(11):1036-9. Review.

PMID:
7874490
48.

Ciliary neurotrophic factor.

Sendtner M, Carroll P, Holtmann B, Hughes RA, Thoenen H.

J Neurobiol. 1994 Nov;25(11):1436-53. Review.

PMID:
7852996
49.

Activity-dependent and hormonal regulation of neurotrophin mRNA levels in the brain--implications for neuronal plasticity.

Lindholm D, Castrén E, Berzaghi M, Blöchl A, Thoenen H.

J Neurobiol. 1994 Nov;25(11):1362-72. Review.

PMID:
7852991
50.

bcl-2 messenger RNA is localized in neurons of the developing and adult rat brain.

Castrén E, Ohga Y, Berzaghi MP, Tzimagiorgis G, Thoenen H, Lindholm D.

Neuroscience. 1994 Jul;61(1):165-77.

PMID:
7969891

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