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Items: 1 to 50 of 89

1.

Multi-Compartment Profiling of Bacterial and Host Metabolites Identifies Intestinal Dysbiosis and Its Functional Consequences in the Critically Ill Child.

Wijeyesekera A, Wagner J, De Goffau M, Thurston S, Rodrigues Sabino A, Zaher S, White D, Ridout J, Peters MJ, Ramnarayan P, Branco RG, Torok ME, Valla F, Meyer R, Klein N, Frost G, Parkhill J, Holmes E, Pathan N.

Crit Care Med. 2019 Sep;47(9):e727-e734. doi: 10.1097/CCM.0000000000003841.

2.

An outbreak of meticillin-resistant Staphylococcus aureus colonization in a neonatal intensive care unit: use of a case-control study to investigate and control it and lessons learnt.

Brown NM, Reacher M, Rice W, Roddick I, Reeve L, Verlander NQ, Broster S, Ogilvy-Stuart AL, D'Amore A, Ahluwalia J, Robinson S, Thaxter R, Moody C, Kearns A, Greatorex J, Martin H, Török ME, Enoch DA.

J Hosp Infect. 2019 May 24. pii: S0195-6701(19)30222-1. doi: 10.1016/j.jhin.2019.05.009. [Epub ahead of print]

PMID:
31132394
3.

Dynamic prediction of death in patients with tuberculous meningitis using time-updated Glasgow coma score and plasma sodium measurements.

Thao LTP, Wolbers M, Heemskerk AD, Thi Hoang Mai N, Thi Minh Ha D, Thi Hong Chau T, Hoan Phu N, Van Vinh Chau N, Caws M, Huu Lan N, Dang Anh Thu D, Thuy Thuong Thuong N, Day J, Torok ME, Duc Bang N, Thwaites GE, Geskus RB.

Clin Infect Dis. 2019 Apr 4. pii: ciz262. doi: 10.1093/cid/ciz262. [Epub ahead of print]

PMID:
30944929
4.

Prospective genomic surveillance of methicillin-resistant Staphylococcus aureus (MRSA) associated with bloodstream infection, England, 1 October 2012 to 30 September 2013.

Toleman MS, Reuter S, Jamrozy D, Wilson HJ, Blane B, Harrison EM, Coll F, Hope RJ, Kearns A, Parkhill J, Peacock SJ, Török ME.

Euro Surveill. 2019 Jan;24(4). doi: 10.2807/1560-7917.ES.2019.24.4.1800215.

5.

Adjunctive rifampicin to reduce early mortality from Staphylococcus aureus bacteraemia: the ARREST RCT.

Thwaites GE, Scarborough M, Szubert A, Saramago Goncalves P, Soares M, Bostock J, Nsutebu E, Tilley R, Cunningham R, Greig J, Wyllie SA, Wilson P, Auckland C, Cairns J, Ward D, Lal P, Guleri A, Jenkins N, Sutton J, Wiselka M, Armando GR, Graham C, Chadwick PR, Barlow G, Gordon NC, Young B, Meisner S, McWhinney P, Price DA, Harvey D, Nayar D, Jeyaratnam D, Planche T, Minton J, Hudson F, Hopkins S, Williams J, Török ME, Llewelyn MJ, Edgeworth JD, Walker AS.

Health Technol Assess. 2018 Oct;22(59):1-148. doi: 10.3310/hta22590.

6.

Extended-spectrum β-lactamase-producing and carbapenemase-producing Enterobacteriaceae.

Wilson H, Török ME.

Microb Genom. 2018 Jul;4(7). doi: 10.1099/mgen.0.000197. Epub 2018 Jul 23. Erratum in: Microb Genom. 2018 Sep;4(9):.

7.

Point-prevalence survey of carbapenemase-producing Enterobacteriaceae and vancomycin-resistant enterococci in adult inpatients in a university teaching hospital in the UK.

Wilson HJ, Khokhar F, Enoch DA, Brown NM, Ahluwalia J, Dougan G, Török ME.

J Hosp Infect. 2018 Sep;100(1):35-39. doi: 10.1016/j.jhin.2018.06.024. Epub 2018 Jun 30.

8.

Erratum: Antimicrobial resistance in human populations: challenges and opportunities - ERRATUM.

Allcock S, Young EH, Holmes M, Gurdasani D, Dougan G, Sandhu MS, Solomon L, Török ME.

Glob Health Epidemiol Genom. 2017 Oct 27;2:e16. doi: 10.1017/gheg.2017.12. eCollection 2017.

9.

Duration of exposure to multiple antibiotics is associated with increased risk of VRE bacteraemia: a nested case-control study.

Gouliouris T, Warne B, Cartwright EJP, Bedford L, Weerasuriya CK, Raven KE, Brown NM, Török ME, Limmathurotsakul D, Peacock SJ.

J Antimicrob Chemother. 2018 Jun 1;73(6):1692-1699. doi: 10.1093/jac/dky075.

10.

Absence of cerebrospinal fluid pleocytosis in tuberculous meningitis is a common occurrence in HIV co-infection and a predictor of poor outcomes.

Cresswell FV, Bangdiwala AS, Meya DB, Bahr NC, Vidal JE, Török ME, Thao LTP, Thwaites GE, Boulware DR.

Int J Infect Dis. 2018 Mar;68:77-78. doi: 10.1016/j.ijid.2018.01.014. Epub 2018 Jan 31. No abstract available.

11.

Within-host evolution of Enterococcus faecium during longitudinal carriage and transition to bloodstream infection in immunocompromised patients.

Moradigaravand D, Gouliouris T, Blane B, Naydenova P, Ludden C, Crawley C, Brown NM, Török ME, Parkhill J, Peacock SJ.

Genome Med. 2017 Dec 27;9(1):119. doi: 10.1186/s13073-017-0507-0.

12.

Convergent evolution and topologically disruptive polymorphisms among multidrug-resistant tuberculosis in Peru.

Grandjean L, Gilman RH, Iwamoto T, Köser CU, Coronel J, Zimic M, Török ME, Ayabina D, Kendall M, Fraser C, Harris S, Parkhill J, Peacock SJ, Moore DAJ, Colijn C.

PLoS One. 2017 Dec 27;12(12):e0189838. doi: 10.1371/journal.pone.0189838. eCollection 2017.

13.

Antimicrobial resistance in human populations: challenges and opportunities.

Allcock S, Young EH, Holmes M, Gurdasani D, Dougan G, Sandhu MS, Solomon L, Török ME.

Glob Health Epidemiol Genom. 2017 May 10;2:e4. doi: 10.1017/gheg.2017.4. eCollection 2017. Review. Erratum in: Glob Health Epidemiol Genom. 2017 Oct 27;2:e16.

14.

Adjunctive rifampicin for Staphylococcus aureus bacteraemia (ARREST): a multicentre, randomised, double-blind, placebo-controlled trial.

Thwaites GE, Scarborough M, Szubert A, Nsutebu E, Tilley R, Greig J, Wyllie SA, Wilson P, Auckland C, Cairns J, Ward D, Lal P, Guleri A, Jenkins N, Sutton J, Wiselka M, Armando GR, Graham C, Chadwick PR, Barlow G, Gordon NC, Young B, Meisner S, McWhinney P, Price DA, Harvey D, Nayar D, Jeyaratnam D, Planche T, Minton J, Hudson F, Hopkins S, Williams J, Török ME, Llewelyn MJ, Edgeworth JD, Walker AS; United Kingdom Clinical Infection Research Group (UKCIRG).

Lancet. 2018 Feb 17;391(10121):668-678. doi: 10.1016/S0140-6736(17)32456-X. Epub 2017 Dec 14.

15.

Longitudinal genomic surveillance of MRSA in the UK reveals transmission patterns in hospitals and the community.

Coll F, Harrison EM, Toleman MS, Reuter S, Raven KE, Blane B, Palmer B, Kappeler ARM, Brown NM, Török ME, Parkhill J, Peacock SJ.

Sci Transl Med. 2017 Oct 25;9(413). pii: eaak9745. doi: 10.1126/scitranslmed.aak9745. Epub 2017 Oct 25.

16.

Prognostic Models for 9-Month Mortality in Tuberculous Meningitis.

Thao LTP, Heemskerk AD, Geskus RB, Mai NTH, Ha DTM, Chau TTH, Phu NH, Chau NVV, Caws M, Lan NH, Thu DDA, Thuong NTT, Day J, Farrar JJ, Torok ME, Bang ND, Thwaites GE, Wolbers M.

Clin Infect Dis. 2018 Feb 1;66(4):523-532. doi: 10.1093/cid/cix849.

17.

Population genetic structuring of methicillin-resistant Staphylococcus aureus clone EMRSA-15 within UK reflects patient referral patterns.

Donker T, Reuter S, Scriberras J, Reynolds R, Brown NM, Török ME, James R, Network EOEMR, Aanensen DM, Bentley SD, Holden MTG, Parkhill J, Spratt BG, Peacock SJ, Feil EJ, Grundmann H.

Microb Genom. 2017 Jul 4;3(7):e000113. doi: 10.1099/mgen.0.000113. eCollection 2017 Jul.

18.

Corrigendum: Building a genomic framework for prospective MRSA surveillance in the United Kingdom and the Republic of Ireland.

Reuter S, Török ME, Holden MTG, Reynolds R, Raven KE, Blane B, Donker T, Bentley SD, Aanensen DM, Grundmann H, Feil EJ, Spratt BG, Parkhill J, Peacock SJ.

Genome Res. 2017 Sep;27(9):1622. doi: 10.1101/gr.228155.117. No abstract available.

19.

Community outbreaks of group A Streptococcus revealed by genome sequencing.

Turner CE, Bedford L, Brown NM, Judge K, Török ME, Parkhill J, Peacock SJ.

Sci Rep. 2017 Aug 17;7(1):8554. doi: 10.1038/s41598-017-08914-x.

20.

Genomic surveillance reveals low prevalence of livestock-associated methicillin-resistant Staphylococcus aureus in the East of England.

Harrison EM, Coll F, Toleman MS, Blane B, Brown NM, Török ME, Parkhill J, Peacock SJ.

Sci Rep. 2017 Aug 7;7(1):7406. doi: 10.1038/s41598-017-07662-2.

21.

Clonal differences in Staphylococcus aureus bacteraemia-associated mortality.

Recker M, Laabei M, Toleman MS, Reuter S, Saunderson RB, Blane B, Török ME, Ouadi K, Stevens E, Yokoyama M, Steventon J, Thompson L, Milne G, Bayliss S, Bacon L, Peacock SJ, Massey RC.

Nat Microbiol. 2017 Oct;2(10):1381-1388. doi: 10.1038/s41564-017-0001-x. Epub 2017 Aug 7.

22.

Longitudinal genomic surveillance of multidrug-resistant Escherichia coli carriage in a long-term care facility in the United Kingdom.

Brodrick HJ, Raven KE, Kallonen T, Jamrozy D, Blane B, Brown NM, Martin V, Török ME, Parkhill J, Peacock SJ.

Genome Med. 2017 Jul 25;9(1):70. doi: 10.1186/s13073-017-0457-6.

23.

Complex Routes of Nosocomial Vancomycin-Resistant Enterococcus faecium Transmission Revealed by Genome Sequencing.

Raven KE, Gouliouris T, Brodrick H, Coll F, Brown NM, Reynolds R, Reuter S, Török ME, Parkhill J, Peacock SJ.

Clin Infect Dis. 2017 Apr 1;64(7):886-893. doi: 10.1093/cid/ciw872.

24.

Suboptimal Exposure to Anti-TB Drugs in a TBM/HIV+ Population Is Not Related to Antiretroviral Therapy.

Török ME, Aljayyoussi G, Waterhouse D, Chau T, Mai N, Phu NH, Hien TT, Hope W, Farrar JJ, Ward SA.

Clin Pharmacol Ther. 2018 Mar;103(3):449-457. doi: 10.1002/cpt.646. Epub 2017 Dec 6.

PMID:
28160272
25.

Transmission of methicillin-resistant Staphylococcus aureus in long-term care facilities and their related healthcare networks.

Harrison EM, Ludden C, Brodrick HJ, Blane B, Brennan G, Morris D, Coll F, Reuter S, Brown NM, Holmes MA, O'Connell B, Parkhill J, Török ME, Cormican M, Peacock SJ.

Genome Med. 2016 Oct 3;8(1):102.

26.

Genome-based characterization of hospital-adapted Enterococcus faecalis lineages.

Raven KE, Reuter S, Gouliouris T, Reynolds R, Russell JE, Brown NM, Török ME, Parkhill J, Peacock SJ.

Nat Microbiol. 2016 Feb 8;1:15033. doi: 10.1038/nmicrobiol.2015.33.

PMID:
27572164
27.

A decade of genomic history for healthcare-associated Enterococcus faecium in the United Kingdom and Ireland.

Raven KE, Reuter S, Reynolds R, Brodrick HJ, Russell JE, Török ME, Parkhill J, Peacock SJ.

Genome Res. 2016 Oct;26(10):1388-1396. Epub 2016 Aug 15.

28.

Indoor Air Pollution and Delayed Measles Vaccination Increase the Risk of Severe Pneumonia in Children: Results from a Case-Control Study in Mwanza, Tanzania.

PrayGod G, Mukerebe C, Magawa R, Jeremiah K, Török ME.

PLoS One. 2016 Aug 10;11(8):e0160804. doi: 10.1371/journal.pone.0160804. eCollection 2016.

29.

Comparison of two chromogenic media for the detection of vancomycin-resistant enterococcal carriage by nursing home residents.

Gouliouris T, Blane B, Brodrick HJ, Raven KE, Ambridge KE, Kidney AD, Hadjirin NF, Török ME, Limmathurotsakul D, Peacock SJ.

Diagn Microbiol Infect Dis. 2016 Aug;85(4):409-12. doi: 10.1016/j.diagmicrobio.2016.04.026. Epub 2016 May 4.

30.

Genome-based characterization of hospital-adapted Enterococcus faecalis lineages.

Raven KE, Reuter S, Gouliouris T, Reynolds R, Russell JE, Brown NM, Török ME, Parkhill J, Peacock SJ.

Nat Microbiol. 2016 Mar;1(3). pii: 15033. Epub 2016 Feb 8.

31.

Efavirenz and Metabolites in Cerebrospinal Fluid: Relationship with CYP2B6 c.516G→T Genotype and Perturbed Blood-Brain Barrier Due to Tuberculous Meningitis.

Nightingale S, Chau TT, Fisher M, Nelson M, Winston A, Else L, Carr DF, Taylor S, Ustianowski A, Back D, Pirmohamed M, Solomon T, Farrar J, Törok ME, Khoo S.

Antimicrob Agents Chemother. 2016 Jul 22;60(8):4511-8. doi: 10.1128/AAC.00280-16. Print 2016 Aug.

32.

Systematic Surveillance Detects Multiple Silent Introductions and Household Transmission of Methicillin-Resistant Staphylococcus aureus USA300 in the East of England.

Toleman MS, Reuter S, Coll F, Harrison EM, Blane B, Brown NM, Török ME, Parkhill J, Peacock SJ.

J Infect Dis. 2016 Aug 1;214(3):447-53. doi: 10.1093/infdis/jiw166. Epub 2016 Apr 27.

33.

dfrA thyA Double Deletion in para-Aminosalicylic Acid-Resistant Mycobacterium tuberculosis Beijing Strains.

Moradigaravand D, Grandjean L, Martinez E, Li H, Zheng J, Coronel J, Moore D, Török ME, Sintchenko V, Huang H, Javid B, Parkhill J, Peacock SJ, Köser CU.

Antimicrob Agents Chemother. 2016 May 23;60(6):3864-7. doi: 10.1128/AAC.00253-16. Print 2016 Jun. No abstract available.

34.

Methicillin-resistant Staphylococcus aureus multiple sites surveillance: a systemic review of the literature.

Chipolombwe J, Török ME, Mbelle N, Nyasulu P.

Infect Drug Resist. 2016 Feb 12;9:35-42. doi: 10.2147/IDR.S95372. eCollection 2016. Review.

35.

Whole-genome sequencing reveals transmission of vancomycin-resistant Enterococcus faecium in a healthcare network.

Brodrick HJ, Raven KE, Harrison EM, Blane B, Reuter S, Török ME, Parkhill J, Peacock SJ.

Genome Med. 2016 Jan 12;8(1):4. doi: 10.1186/s13073-015-0259-7.

36.

Whole-genome sequencing for the diagnosis of drug-resistant tuberculosis.

Javid B, Török ME.

Lancet Infect Dis. 2016 Jan;16(1):17. doi: 10.1016/S1473-3099(15)00474-0. No abstract available.

PMID:
26738825
37.

Comparison of 2 chromogenic media for the detection of extended-spectrum β-lactamase producing Enterobacteriaceae stool carriage in nursing home residents.

Blane B, Brodrick HJ, Gouliouris T, Ambridge KE, Kidney AD, Ludden CM, Limmathurotsakul D, Török ME, Peacock SJ.

Diagn Microbiol Infect Dis. 2016 Mar;84(3):181-3. doi: 10.1016/j.diagmicrobio.2015.11.008. Epub 2015 Nov 11.

38.

Building a genomic framework for prospective MRSA surveillance in the United Kingdom and the Republic of Ireland.

Reuter S, Török ME, Holden MT, Reynolds R, Raven KE, Blane B, Donker T, Bentley SD, Aanensen DM, Grundmann H, Feil EJ, Spratt BG, Parkhill J, Peacock SJ.

Genome Res. 2016 Feb;26(2):263-70. doi: 10.1101/gr.196709.115. Epub 2015 Dec 15. Erratum in: Genome Res. 2017 Sep;27(9):1622.

39.

Impact of routine bedside infectious disease consultation on clinical management and outcome of Staphylococcus aureus bacteraemia in adults.

Saunderson RB, Gouliouris T, Nickerson EK, Cartwright EJ, Kidney A, Aliyu SH, Brown NM, Limmathurotsakul D, Peacock SJ, Török ME.

Clin Microbiol Infect. 2015 Aug;21(8):779-85. doi: 10.1016/j.cmi.2015.05.026. Epub 2015 May 29.

40.

Emergent and evolving antimicrobial resistance cassettes in community-associated fusidic acid and meticillin-resistant Staphylococcus aureus.

Ellington MJ, Reuter S, Harris SR, Holden MT, Cartwright EJ, Greaves D, Gerver SM, Hope R, Brown NM, Török ME, Parkhill J, Köser CU, Peacock SJ.

Int J Antimicrob Agents. 2015 May;45(5):477-84. doi: 10.1016/j.ijantimicag.2015.01.009. Epub 2015 Feb 19.

41.

Drug-resistance mechanisms and tuberculosis drugs.

Köser CU, Javid B, Liddell K, Ellington MJ, Feuerriegel S, Niemann S, Brown NM, Burman WJ, Abubakar I, Ismail NA, Moore D, Peacock SJ, Török ME.

Lancet. 2015 Jan 24;385(9965):305-7. doi: 10.1016/S0140-6736(14)62450-8. No abstract available.

42.

Tuberculous meningitis: advances in diagnosis and treatment.

Török ME.

Br Med Bull. 2015 Mar;113(1):117-31. doi: 10.1093/bmb/ldv003. Epub 2015 Feb 18. Review.

PMID:
25693576
43.

Public perceptions of bacterial whole-genome sequencing for tuberculosis.

Davies A, Scott S, Badger S, Török ME, Peacock SJ.

Trends Genet. 2015 Feb;31(2):58-60. doi: 10.1016/j.tig.2014.08.002. Epub 2014 Nov 14.

PMID:
25640860
44.

Characterization of plasmids in extensively drug-resistant acinetobacter strains isolated in India and Pakistan.

Jones LS, Carvalho MJ, Toleman MA, White PL, Connor TR, Mushtaq A, Weeks JL, Kumarasamy KK, Raven KE, Török ME, Peacock SJ, Howe RA, Walsh TR.

Antimicrob Agents Chemother. 2015 Feb;59(2):923-9. doi: 10.1128/AAC.03242-14. Epub 2014 Nov 24.

45.

Innate immunity. A Spaetzle-like role for nerve growth factor β in vertebrate immunity to Staphylococcus aureus.

Hepburn L, Prajsnar TK, Klapholz C, Moreno P, Loynes CA, Ogryzko NV, Brown K, Schiebler M, Hegyi K, Antrobus R, Hammond KL, Connolly J, Ochoa B, Bryant C, Otto M, Surewaard B, Seneviratne SL, Grogono DM, Cachat J, Ny T, Kaser A, Török ME, Peacock SJ, Holden M, Blundell T, Wang L, Ligoxygakis P, Minichiello L, Woods CG, Foster SJ, Renshaw SA, Floto RA.

Science. 2014 Oct 31;346(6209):641-646. doi: 10.1126/science.1258705.

46.

Impact of infectious diseases consultation on the management of Staphylococcus aureus bacteraemia in children.

Saunderson RB, Gouliouris T, Cartwright EJ, Nickerson EJ, Aliyu SH, O'Donnell DR, Kelsall W, Limmathurotsakul D, Peacock SJ, Török ME.

BMJ Open. 2014 Jul 1;4(7):e004659. doi: 10.1136/bmjopen-2013-004659.

47.

Zero tolerance for healthcare-associated MRSA bacteraemia: is it realistic?

Török ME, Harris SR, Cartwright EJ, Raven KE, Brown NM, Allison ME, Greaves D, Quail MA, Limmathurotsakul D, Holden MT, Parkhill J, Peacock SJ.

J Antimicrob Chemother. 2014 Aug;69(8):2238-45. doi: 10.1093/jac/dku128. Epub 2014 Apr 30.

48.

Rapid single-colony whole-genome sequencing of bacterial pathogens.

Köser CU, Fraser LJ, Ioannou A, Becq J, Ellington MJ, Holden MT, Reuter S, Török ME, Bentley SD, Parkhill J, Gormley NA, Smith GP, Peacock SJ.

J Antimicrob Chemother. 2014 May;69(5):1275-81. doi: 10.1093/jac/dkt494. Epub 2013 Dec 25.

49.

Prevalence and characterization of human mecC methicillin-resistant Staphylococcus aureus isolates in England.

Paterson GK, Morgan FJ, Harrison EM, Cartwright EJ, Török ME, Zadoks RN, Parkhill J, Peacock SJ, Holmes MA.

J Antimicrob Chemother. 2014 Apr;69(4):907-10. doi: 10.1093/jac/dkt462. Epub 2013 Nov 27.

50.

Staphylococcus aureus bloodstream infection: a pooled analysis of five prospective, observational studies.

Kaasch AJ, Barlow G, Edgeworth JD, Fowler VG Jr, Hellmich M, Hopkins S, Kern WV, Llewelyn MJ, Rieg S, Rodriguez-Baño J, Scarborough M, Seifert H, Soriano A, Tilley R, Tőrők ME, Weiß V, Wilson AP, Thwaites GE; ISAC, INSTINCT, SABG, UKCIRG, and Colleagues.

J Infect. 2014 Mar;68(3):242-51. doi: 10.1016/j.jinf.2013.10.015. Epub 2013 Nov 16. Erratum in: J Infect. 2014 Sep;69(3):306-7.

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