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Items: 1 to 50 of 65

1.

Decellularized pig pulmonary heart valves-Depletion of nucleic acids measured by proviral PERV pol.

Godehardt AW, Ramm R, Gulich B, Tönjes RR, Hilfiker A.

Xenotransplantation. 2019 Nov 6:e12565. doi: 10.1111/xen.12565. [Epub ahead of print]

PMID:
31692126
2.

Characterization of porcine endogenous retrovirus particles released by the CRISPR/Cas9 inactivated cell line PK15 clone 15.

Godehardt AW, Fischer N, Rauch P, Gulich B, Boller K, Church GM, Tönjes RR.

Xenotransplantation. 2019 Oct 31:e12563. doi: 10.1111/xen.12563. [Epub ahead of print]

PMID:
31667881
3.

Third WHO Global Consultation on Regulatory Requirements for Xenotransplantation Clinical Trials, Changsha, Hunan, China December 12-14, 2018: "The 2018 Changsha Communiqué" The 10-Year Anniversary of The International Consultation on Xenotransplantation.

Hawthorne WJ, Cowan PJ, Bühler LH, Yi S, Bottino R, Pierson RN 3rd, Ahn C, Azimzadeh A, Cozzi E, Gianello P, Lakey JRT, Luo M, Miyagawa S, Mohiuddin MM, Park CG, Schuurman HJ, Scobie L, Sykes M, Tector J, Tönjes RR, Wolf E, Nuñez JR, Wang W.

Xenotransplantation. 2019 Mar;26(2):e12513. doi: 10.1111/xen.12513. Epub 2019 Apr 13. No abstract available.

PMID:
30980428
4.

Comparative gene expression profiling of pig-derived iPSC-like cells: Effects of induced pluripotency on expression of porcine endogenous retrovirus (PERV).

Godehardt AW, Petkov S, Gulich B, Fischer N, Niemann H, Tönjes RR.

Xenotransplantation. 2018 Jul;25(4):e12429. doi: 10.1111/xen.12429.

PMID:
30264886
5.

Non-viral pathogens: Identification, relevance, and prevention for xenotransplantation.

Tönjes RR.

Xenotransplantation. 2018 May;25(3):e12413. doi: 10.1111/xen.12413.

PMID:
29913046
6.

Joint FDA‐IXA Symposium, September 20, 2017.

Cooper DKC, Cowan P, Fishman JA, Hering BJ, Mohiuddin MM, Pierson RN 3rd, Sachs DH, Schuurman HJ, Dennis JU, Tönjes RR.

Xenotransplantation. 2017 Nov;24(6). doi: 10.1111/xen.12365. Epub 2017 Nov 28. No abstract available. Erratum in: Xenotransplantation. 2018 Nov;25(6):e12477.

PMID:
29193342
7.

First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes--Chapter 1: update on national regulatory frameworks pertinent to clinical islet xenotransplantation.

Cozzi E, Tönjes RR, Gianello P, Bühler LH, Rayat GR, Matsumoto S, Park CG, Kwon I, Wang W, O'Connell P, Jessamine S, Elliott RB, Kobayashi T, Hering BJ.

Xenotransplantation. 2016 Jan-Feb;23(1):14-24. doi: 10.1111/xen.12222. Epub 2016 Mar 4.

PMID:
26940509
9.

[Xenogeneic cell therapeutics: Treatment of type 1 diabetes using porcine pancreatic islets and islet cells].

Godehardt AW, Schilling-Leiß D, Sanzenbacher R, Tönjes RR.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2015 Nov;58(11-12):1281-8. doi: 10.1007/s00103-015-2246-y. Review. German.

PMID:
26369761
10.

Review on porcine endogenous retrovirus detection assays--impact on quality and safety of xenotransplants.

Godehardt AW, Rodrigues Costa M, Tönjes RR.

Xenotransplantation. 2015 Mar-Apr;22(2):95-101. doi: 10.1111/xen.12154. Epub 2015 Jan 31. Review.

11.

Xenotransplantation of porcine islet cells as a potential option for the treatment of type 1 diabetes in the future.

Reichart B, Niemann H, Chavakis T, Denner J, Jaeckel E, Ludwig B, Marckmann G, Schnieke A, Schwinzer R, Seissler J, Tönjes RR, Klymiuk N, Wolf E, Bornstein SR.

Horm Metab Res. 2015 Jan;47(1):31-5. doi: 10.1055/s-0034-1395518. Epub 2014 Dec 15. Review.

PMID:
25506683
12.

Human endogenous retrovirus-K(II) envelope induction protects neurons during HIV/AIDS.

Bhat RK, Rudnick W, Antony JM, Maingat F, Ellestad KK, Wheatley BM, Tönjes RR, Power C.

PLoS One. 2014 Jul 2;9(7):e97984. doi: 10.1371/journal.pone.0097984. eCollection 2014.

13.

Comparison of porcine endogenous retroviruses infectious potential in supernatants of producer cells and in cocultures.

Costa MR, Fischer N, Gulich B, Tönjes RR.

Xenotransplantation. 2014 Mar-Apr;21(2):162-73. doi: 10.1111/xen.12081. Epub 2014 Jan 21.

PMID:
24447212
14.

[Report on notifications according to section 8d of the German Transplantation Act (TPG) for the years 2009-2011].

Schilling-Leiß D, Witt F, Tönjes RR.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2014 Jan;57(1):111-27. doi: 10.1007/s00103-013-1881-4. German.

PMID:
24317302
15.

Infection barriers to successful xenotransplantation focusing on porcine endogenous retroviruses.

Denner J, Tönjes RR.

Clin Microbiol Rev. 2012 Apr;25(2):318-43. doi: 10.1128/CMR.05011-11. Review.

16.

[Report on notifications according to Section 8d of the German Transplantation Act (TPG) for the year 2008].

Schilling-Leiss D, Bracone F, Selbert M, Reinmann L, Tönjes RR.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2011 Sep;54(9):1116-25. doi: 10.1007/s00103-011-1344-8. German.

PMID:
21814744
17.

Development of sensitive methods for detection of porcine endogenous retrovirus-C (PERV-C) in the genome of pigs.

Kaulitz D, Mihica D, Dorna J, Costa MR, Petersen B, Niemann H, Tönjes RR, Denner J.

J Virol Methods. 2011 Jul;175(1):60-5. doi: 10.1016/j.jviromet.2011.04.017. Epub 2011 Apr 29.

PMID:
21539860
18.

Restriction of porcine endogenous retrovirus by porcine APOBEC3 cytidine deaminases.

Dörrschuck E, Fischer N, Bravo IG, Hanschmann KM, Kuiper H, Spötter A, Möller R, Cichutek K, Münk C, Tönjes RR.

J Virol. 2011 Apr;85(8):3842-57. doi: 10.1128/JVI.01880-10. Epub 2011 Feb 9.

19.

Absence of infection in pigs inoculated with high-titre recombinant PERV-A/C.

Kaulitz D, Mihica D, Plesker R, Geissler A, Tönjes RR, Denner J.

Arch Virol. 2011 Apr;156(4):707-10. doi: 10.1007/s00705-010-0896-5. Epub 2011 Jan 1.

PMID:
21197554
20.

Retroviral restriction factors and infectious risk in xenotransplantation.

Meije Y, Tönjes RR, Fishman JA.

Am J Transplant. 2010 Jul;10(7):1511-6. doi: 10.1111/j.1600-6143.2010.03146.x.

21.

APOBEC3 proteins and porcine endogenous retroviruses.

Dörrschuck E, Münk C, Tönjes RR.

Transplant Proc. 2008 May;40(4):959-61. doi: 10.1016/j.transproceed.2008.03.032.

PMID:
18555089
22.

Retrotransposition: another obstacle for xenotransplantation?

Jungmann A, Tönjes RR.

Transplant Proc. 2008 Mar;40(2):596-7. doi: 10.1016/j.transproceed.2008.01.001.

PMID:
18374139
23.

Human endogenous retrovirus HERV-K113 is capable of producing intact viral particles.

Boller K, Schönfeld K, Lischer S, Fischer N, Hoffmann A, Kurth R, Tönjes RR.

J Gen Virol. 2008 Feb;89(Pt 2):567-572. doi: 10.1099/vir.0.83534-0.

PMID:
18198388
24.

Transient transmission of porcine endogenous retrovirus to fetal lambs after pig islet tissue xenotransplantation.

Popp SK, Mann DA, Milburn PJ, Gibbs AJ, McCullagh PJ, Wilson JD, Tönjes RR, Simeonovic CJ.

Immunol Cell Biol. 2007 Apr-May;85(3):238-48. Epub 2007 Jan 16.

PMID:
17228325
25.
26.

Response to editors' letter in Xenotransplantation on manuscripts on porcine endogenous retroviruses.

Denner J, Tönjes RR.

Xenotransplantation. 2006 Jul;13(4):282-3. No abstract available.

PMID:
16768720
27.
28.
30.
32.

Molecular cloning and functional characterization of infectious PERV and development of diagnostic tests.

Niebert M, Tönjes RR.

Curr Top Microbiol Immunol. 2003;278:217-37. Review.

PMID:
12934946
33.

Detection of porcine endogenous retrovirus (PERV) using highly specific antisera against Gag and Env.

Fischer N, Krach U, Niebert M, Tönjes RR.

Virology. 2003 Jun 20;311(1):222-8.

34.

Expression and characterization of a recombinant novel reverse transcriptase of a porcine endogenous retrovirus.

Avidan O, Loya S, Tönjes RR, Sevilya Z, Hizi A.

Virology. 2003 Mar 15;307(2):341-57.

36.

Developmental expression of HERV-R (ERV3) and HERV-K in human tissue.

Andersson AC, Venables PJ, Tönjes RR, Scherer J, Eriksson L, Larsson E.

Virology. 2002 Jun 5;297(2):220-5.

37.

A retroviral long terminal repeat adjacent to the HLA DQB1 gene (DQ-LTR13) modifies Type I diabetes susceptibility on high risk DQ haplotypes.

Bieda K, Pani MA, van der Auwera B, Seidl C, Tönjes RR, Gorus F, Usadel KH, Badenhoop K.

Diabetologia. 2002 Mar;45(3):443-7.

PMID:
11914751
40.
41.
42.

Establishment and characterization of molecular clones of porcine endogenous retroviruses replicating on human cells.

Czauderna F, Fischer N, Boller K, Kurth R, Tönjes RR.

J Virol. 2000 May;74(9):4028-38.

43.

Generation and testing of a highly specific anti-serum directed against porcine endogenous retrovirus nucleocapsid.

Krach U, Fischer N, Czauderna F, Kurth R, Tönjes RR.

Xenotransplantation. 2000 Aug;7(3):221-9.

PMID:
11021668
45.

Molecularly cloned porcine endogenous retroviruses replicate on human cells.

Tönjes RR, Czauderna F, Fischer N, Krach U, Boller K, Chardon P, Rogel-Gaillard C, Niebert M, Scheef G, Werner A, Kurth R.

Transplant Proc. 2000 Aug;32(5):1158-61. No abstract available.

PMID:
10936400
46.
47.

Intronic sequence motifs of HLA-DQB1 are shared between humans, apes and Old World monkeys, but a retroviral LTR element (DQLTR3) is human specific.

Donner H, Tönjes RR, Bontrop RE, Kurth R, Usadel KH, Badenhoop K.

Tissue Antigens. 1999 Jun;53(6):551-8.

PMID:
10395105
48.

The presence or absence of a retroviral long terminal repeat influences the genetic risk for type 1 diabetes conferred by human leukocyte antigen DQ haplotypes. Belgian Diabetes Registry.

Donner H, Tönjes RR, Van der Auwera B, Siegmund T, Braun J, Weets I, Herwig J, Kurth R, Usadel KH, Badenhoop K.

J Clin Endocrinol Metab. 1999 Apr;84(4):1404-8.

PMID:
10199786
49.

Reverse transcriptase activity and particle production in B lymphoblastoid cell lines established from lymphocytes of patients with multiple sclerosis.

Christensen T, Tönjes RR, zur Megede J, Boller K, Møller-Larsen A.

AIDS Res Hum Retroviruses. 1999 Feb 10;15(3):285-91.

PMID:
10052759
50.

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