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Items: 1 to 50 of 78

1.

Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain.

Wheeler JM, McMillan P, Strovas TJ, Liachko NF, Amlie-Wolf A, Kow RL, Klein RL, Szot P, Robinson L, Guthrie C, Saxton A, Kanaan NM, Raskind M, Peskind E, Trojanowski JQ, Lee VMY, Wang LS, Keene CD, Bird T, Schellenberg GD, Kraemer B.

Sci Transl Med. 2019 Dec 18;11(523). pii: eaao6545. doi: 10.1126/scitranslmed.aao6545.

PMID:
31852801
2.

Associations between CSF cortisol and CSF norepinephrine in cognitively normal controls and patients with amnestic MCI and AD dementia.

Wang LY, Raskind MA, Wilkinson CW, Shofer JB, Sikkema C, Szot P, Quinn JF, Galasko DR, Peskind ER.

Int J Geriatr Psychiatry. 2018 May;33(5):763-768. doi: 10.1002/gps.4856. Epub 2018 Feb 15.

3.

Multiple lipopolysaccharide (LPS) injections alter interleukin 6 (IL-6), IL-7, IL-10 and IL-6 and IL-7 receptor mRNA in CNS and spleen.

Szot P, Franklin A, Figlewicz DP, Beuca TP, Bullock K, Hansen K, Banks WA, Raskind MA, Peskind ER.

Neuroscience. 2017 Jul 4;355:9-21. doi: 10.1016/j.neuroscience.2017.04.028. Epub 2017 Apr 27.

PMID:
28456715
4.

Cortical adrenoceptor expression, function and adaptation under conditions of cannabinoid receptor deletion.

Reyes BAS, Carvalho AF, Szot P, Kalamarides DJ, Wang Q, Kirby LG, Van Bockstaele EJ.

Exp Neurol. 2017 Jun;292:179-192. doi: 10.1016/j.expneurol.2017.03.010. Epub 2017 Mar 21.

5.

PBrowse: a web-based platform for real-time collaborative exploration of genomic data.

Szot PS, Yang A, Wang X, Parsania C, Röhm U, Wong KH, Ho JWK.

Nucleic Acids Res. 2017 May 19;45(9):e67. doi: 10.1093/nar/gkw1358.

6.

Human Bacterial Artificial Chromosome (BAC) Transgenesis Fully Rescues Noradrenergic Function in Dopamine β-Hydroxylase Knockout Mice.

Cubells JF, Schroeder JP, Barrie ES, Manvich DF, Sadee W, Berg T, Mercer K, Stowe TA, Liles LC, Squires KE, Mezher A, Curtin P, Perdomo DL, Szot P, Weinshenker D.

PLoS One. 2016 May 5;11(5):e0154864. doi: 10.1371/journal.pone.0154864. eCollection 2016.

7.

Depressive-like behavior observed with a minimal loss of locus coeruleus (LC) neurons following administration of 6-hydroxydopamine is associated with electrophysiological changes and reversed with precursors of norepinephrine.

Szot P, Franklin A, Miguelez C, Wang Y, Vidaurrazaga I, Ugedo L, Sikkema C, Wilkinson CW, Raskind MA.

Neuropharmacology. 2016 Feb;101:76-86. doi: 10.1016/j.neuropharm.2015.09.003. Epub 2015 Sep 8.

8.

Sequential Loss of LC Noradrenergic and Dopaminergic Neurons Results in a Correlation of Dopaminergic Neuronal Number to Striatal Dopamine Concentration.

Szot P, Franklin A, Sikkema C, Wilkinson CW, Raskind MA.

Front Pharmacol. 2012 Oct 22;3:184. doi: 10.3389/fphar.2012.00184. eCollection 2012.

9.

Stress-induced sensitization of cortical adrenergic receptors following a history of cannabinoid exposure.

Reyes BA, Szot P, Sikkema C, Cathel AM, Kirby LG, Van Bockstaele EJ.

Exp Neurol. 2012 Aug;236(2):327-35. doi: 10.1016/j.expneurol.2012.05.016. Epub 2012 Jun 4.

10.

Common factors among Alzheimer's disease, Parkinson's disease, and epilepsy: possible role of the noradrenergic nervous system.

Szot P.

Epilepsia. 2012 Jun;53 Suppl 1:61-6. doi: 10.1111/j.1528-1167.2012.03476.x. Review.

11.

Lesioning noradrenergic neurons of the locus coeruleus in C57Bl/6 mice with unilateral 6-hydroxydopamine injection, to assess molecular, electrophysiological and biochemical changes in noradrenergic signaling.

Szot P, Knight L, Franklin A, Sikkema C, Foster S, Wilkinson CW, White SS, Raskind MA.

Neuroscience. 2012 Aug 2;216:143-57. doi: 10.1016/j.neuroscience.2012.04.046. Epub 2012 Apr 25.

12.

An evaluation of neuroplasticity and behavior after deep brain stimulation of the nucleus accumbens in an animal model of depression.

Falowski SM, Sharan A, Reyes BA, Sikkema C, Szot P, Van Bockstaele EJ.

Neurosurgery. 2011 Dec;69(6):1281-90. doi: 10.1227/NEU.0b013e3182237346.

13.

The role of norepinephrine in differential response to stress in an animal model of posttraumatic stress disorder.

Olson VG, Rockett HR, Reh RK, Redila VA, Tran PM, Venkov HA, Defino MC, Hague C, Peskind ER, Szot P, Raskind MA.

Biol Psychiatry. 2011 Sep 1;70(5):441-8. doi: 10.1016/j.biopsych.2010.11.029. Epub 2011 Jan 20.

14.

Differential response of the central noradrenergic nervous system to the loss of locus coeruleus neurons in Parkinson's disease and Alzheimer's disease.

McMillan PJ, White SS, Franklin A, Greenup JL, Leverenz JB, Raskind MA, Szot P.

Brain Res. 2011 Feb 10;1373:240-52. doi: 10.1016/j.brainres.2010.12.015. Epub 2010 Dec 11.

15.

A comprehensive analysis of the effect of DSP4 on the locus coeruleus noradrenergic system in the rat.

Szot P, Miguelez C, White SS, Franklin A, Sikkema C, Wilkinson CW, Ugedo L, Raskind MA.

Neuroscience. 2010 Mar 10;166(1):279-91. doi: 10.1016/j.neuroscience.2009.12.027. Epub 2010 Jan 4.

16.

Age-dependent changes in noradrenergic locus coeruleus system in wild-type and APP23 transgenic mice.

Szot P, Van Dam D, White SS, Franklin A, Staufenbiel M, De Deyn PP.

Neurosci Lett. 2009 Sep 29;463(1):93-7. doi: 10.1016/j.neulet.2009.07.055. Epub 2009 Jul 23.

PMID:
19631722
17.

Stress-induced activity in the locus coeruleus is not sensitive to stressor controllability.

McDevitt RA, Szot P, Baratta MV, Bland ST, White SS, Maier SF, Neumaier JF.

Brain Res. 2009 Aug 18;1285:109-18. doi: 10.1016/j.brainres.2009.06.017. Epub 2009 Jun 12.

18.

[Cholestatic hepatitis as a ticlopidine-induced complication of treatment - a case report].

Kowalski R, Dropiński J, Brzostek T, Szot P, Rzeszutko M, Kasper M, Sawicka A, Szczeklik A.

Kardiol Pol. 2008 Jul;66(7):758-60. Polish.

PMID:
18690567
19.

Changes in adrenoreceptors in the prefrontal cortex of subjects with dementia: evidence of compensatory changes.

Szot P, White SS, Greenup JL, Leverenz JB, Peskind ER, Raskind MA.

Neuroscience. 2007 Apr 25;146(1):471-80. Epub 2007 Feb 26.

20.

Analysis of brain adrenergic receptors in dopamine-beta-hydroxylase knockout mice.

Sanders JD, Szot P, Weinshenker D, Happe HK, Bylund DB, Murrin LC.

Brain Res. 2006 Sep 13;1109(1):45-53. Epub 2006 Jul 18.

PMID:
16854392
21.
22.

Alpha1-adrenoreceptor in human hippocampus: binding and receptor subtype mRNA expression.

Szot P, White SS, Greenup JL, Leverenz JB, Peskind ER, Raskind MA.

Brain Res Mol Brain Res. 2005 Oct 3;139(2):367-71.

PMID:
16039007
23.

Valproic acid, but not lamotrigine, suppresses seizure-induced c-fos and c-Jun mRNA expression.

Szot P, White SS, Shen DD, Anderson GD.

Brain Res Mol Brain Res. 2005 Apr 27;135(1-2):285-9. Epub 2005 Jan 5.

PMID:
15857691
24.

The ketogenic diet does not alter brain expression of orexigenic neuropeptides.

Tabb K, Szot P, White SS, Liles LC, Weinshenker D.

Epilepsy Res. 2004 Nov;62(1):35-9.

PMID:
15519130
25.

The anticonvulsant and proconvulsant effects of alpha2-adrenoreceptor agonists are mediated by distinct populations of alpha2A-adrenoreceptors.

Szot P, Lester M, Laughlin ML, Palmiter RD, Liles LC, Weinshenker D.

Neuroscience. 2004;126(3):795-803.

PMID:
15183527
26.

Chronic cortisol suppresses pituitary and hypothalamic peptide message expression in pigtailed macaques.

Szot P, Wilkinson CW, White SS, Leverenz JB, Greenup JL, Colasurdo EA, Peskind ER, Raskind MA.

Neuroscience. 2004;126(1):241-6.

PMID:
15145089
27.

Age-dependent differences in flurothyl-induced c-fos and c-jun mRNA expression in the mouse brain.

Storey TW, Rho JM, White SS, Sankar R, Szot P.

Dev Neurosci. 2002;24(4):294-9.

PMID:
12457067
28.

Regulation of norepinephrine transporter abundance by catecholamines and desipramine in vivo.

Weinshenker D, White SS, Javors MA, Palmiter RD, Szot P.

Brain Res. 2002 Aug 16;946(2):239-46.

PMID:
12137927
29.

The role of catecholamines in seizure susceptibility: new results using genetically engineered mice.

Weinshenker D, Szot P.

Pharmacol Ther. 2002 Jun;94(3):213-33. Review.

PMID:
12113799
30.

Genetic comparison of seizure control by norepinephrine and neuropeptide Y.

Weinshenker D, Szot P, Miller NS, Rust NC, Hohmann JG, Pyati U, White SS, Palmiter RD.

J Neurosci. 2001 Oct 1;21(19):7764-9.

31.

Behavioral and metabolic features of repetitive seizures in immature and mature rats.

Szot P, White SS, McCarthy EB, Turella A, Rejniak SX, Schwartzkroin PA.

Epilepsy Res. 2001 Sep;46(3):191-203.

PMID:
11518622
32.

Norepinephrine is required for the anticonvulsant effect of the ketogenic diet.

Szot P, Weinshenker D, Rho JM, Storey TW, Schwartzkroin PA.

Brain Res Dev Brain Res. 2001 Aug 23;129(2):211-4.

PMID:
11506865
33.

Alpha(1) and beta(2) adrenoreceptor agonists inhibit pentylenetetrazole-induced seizures in mice lacking norepinephrine.

Weinshenker D, Szot P, Miller NS, Palmiter RD.

J Pharmacol Exp Ther. 2001 Sep;298(3):1042-8.

PMID:
11504801
34.

Tyrosine hydroxylase and norepinephrine transporter mRNA expression in the locus coeruleus in Alzheimer's disease.

Szot P, Leverenz JB, Peskind ER, Kiyasu E, Rohde K, Miller MA, Raskind MA.

Brain Res Mol Brain Res. 2000 Dec 8;84(1-2):135-40.

PMID:
11113540
35.

Morphological plasticity in an infant monkey model of temporal lobe epilepsy.

Jürgen Wenzel H, Born DE, Dubach MF, Gunderson VM, Maravilla KR, Robbins CA, Szot P, Zierath D, Schwartzkroin PA.

Epilepsia. 2000;41 Suppl 6:S70-5.

36.

Changes in 5-HT(7) serotonin receptor mRNA expression with aging in rat brain.

Kohen R, Heidmann DE, Anthony J, White SS, Hamblin MW, Szot P.

Brain Res Mol Brain Res. 2000 Jun 23;79(1-2):163-8.

PMID:
10925155
37.

Norepinephrine-deficient mice have increased susceptibility to seizure-inducing stimuli.

Szot P, Weinshenker D, White SS, Robbins CA, Rust NC, Schwartzkroin PA, Palmiter RD.

J Neurosci. 1999 Dec 15;19(24):10985-92.

38.

Development of a model of status epilepticus in pigtailed macaque infant monkeys.

Gunderson VM, Dubach M, Szot P, Born DE, Wenzel HJ, Maravilla KR, Zierath DK, Robbins CA, Schwartzkroin PA.

Dev Neurosci. 1999 Nov;21(3-5):352-64.

PMID:
10575259
39.

Developmental seizure susceptibility of kv1.1 potassium channel knockout mice.

Rho JM, Szot P, Tempel BL, Schwartzkroin PA.

Dev Neurosci. 1999 Nov;21(3-5):320-7. Review.

PMID:
10575255
40.

Reduced gene expression for dopamine biosynthesis and transport in midbrain neurons of adult male rats exposed prenatally to ethanol.

Szot P, White SS, Veith RC, Rasmussen DD.

Alcohol Clin Exp Res. 1999 Oct;23(10):1643-9.

PMID:
10549997
41.

Neurotransmitter transporters: target for endocrine regulation.

Figlewicz DP, Patterson TA, Zavosh A, Brot MD, Roitman M, Szot P.

Horm Metab Res. 1999 May;31(5):335-9. Review.

PMID:
10422731
43.

Function and distribution of three rat 5-hydroxytryptamine7 (5-HT7) receptor isoforms produced by alternative splicing.

Heidmann DE, Szot P, Kohen R, Hamblin MW.

Neuropharmacology. 1998 Dec;37(12):1621-32.

PMID:
9886685
44.

Bupropion and desipramine increase dopamine transporter mRNA expression in the ventral tegmental area/substantia nigra of rat brain.

Petrie EC, Veith RC, Szot P.

Prog Neuropsychopharmacol Biol Psychiatry. 1998 Jul;22(5):845-56.

PMID:
9723124
45.

Food deprivation decreases mRNA and activity of the rat dopamine transporter.

Patterson TA, Brot MD, Zavosh A, Schenk JO, Szot P, Figlewicz DP.

Neuroendocrinology. 1998 Jul;68(1):11-20.

PMID:
9695934
46.

Dopamine transporter mRNA is increased in the CNS of Zucker fatty (fa/fa) rats.

Figlewicz DP, Patterson TA, Johnson LB, Zavosh A, Israel PA, Szot P.

Brain Res Bull. 1998 Jun;46(3):199-202.

PMID:
9667812
47.

Sensitization with clozapine: beyond the dopamine hypothesis.

Stevens JR, Denney D, Szot P.

Biol Psychiatry. 1997 Nov 1;42(9):771-80.

PMID:
9347126
48.

Learned helplessness increases 5-hydroxytryptamine1B receptor mRNA levels in the rat dorsal raphe nucleus.

Neumaier JF, Petty F, Kramer GL, Szot P, Hamblin MW.

Biol Psychiatry. 1997 Mar 15;41(6):668-74.

PMID:
9066990
49.

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