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Items: 13


Sustained hyperosmolarity increses TGF-ß1 and Egr-1 expression in the rat renal medulla.

Mózes MM, Szoleczky P, Rosivall L, Kökény G.

BMC Nephrol. 2017 Jul 3;18(1):209. doi: 10.1186/s12882-017-0626-2.


Screening of a composite library of clinically used drugs and well-characterized pharmacological compounds for cystathionine β-synthase inhibition identifies benserazide as a drug potentially suitable for repurposing for the experimental therapy of colon cancer.

Druzhyna N, Szczesny B, Olah G, Módis K, Asimakopoulou A, Pavlidou A, Szoleczky P, Gerö D, Yanagi K, Törö G, López-García I, Myrianthopoulos V, Mikros E, Zatarain JR, Chao C, Papapetropoulos A, Hellmich MR, Szabo C.

Pharmacol Res. 2016 Nov;113(Pt A):18-37. doi: 10.1016/j.phrs.2016.08.016. Epub 2016 Aug 10.


Development of a stretch-induced neurotrauma model for medium-throughput screening in vitro: identification of rifampicin as a neuroprotectant.

López-García I, Gerő D, Szczesny B, Szoleczky P, Olah G, Módis K, Zhang K, Gao J, Wu P, Sowers LC, DeWitt D, Prough DS, Szabo C.

Br J Pharmacol. 2018 Jan;175(2):284-300. doi: 10.1111/bph.13642. Epub 2016 Nov 15.


The HIV Protease Inhibitor Saquinavir Inhibits HMGB1-Driven Inflammation by Targeting the Interaction of Cathepsin V with TLR4/MyD88.

Pribis JP, Al-Abed Y, Yang H, Gero D, Xu H, Montenegro MF, Bauer EM, Kim S, Chavan SS, Cai C, Li T, Szoleczky P, Szabo C, Tracey KJ, Billiar TR.

Mol Med. 2015 Dec;21(1):749-757. doi: 10.2119/molmed.2015.00197. Epub 2015 Sep 2.


Modulation of poly(ADP-ribose) polymerase-1 (PARP-1)-mediated oxidative cell injury by ring finger protein 146 (RNF146) in cardiac myocytes.

Gerö D, Szoleczky P, Chatzianastasiou A, Papapetropoulos A, Szabo C.

Mol Med. 2014 Jul 31;20:313-28. doi: 10.2119/molmed.2014.00102.


Identification of pharmacological modulators of HMGB1-induced inflammatory response by cell-based screening.

Gerö D, Szoleczky P, Módis K, Pribis JP, Al-Abed Y, Yang H, Chevan S, Billiar TR, Tracey KJ, Szabo C.

PLoS One. 2013 Jun 14;8(6):e65994. doi: 10.1371/journal.pone.0065994. Print 2013.


Adenosine and inosine exert cytoprotective effects in an in vitro model of liver ischemia-reperfusion injury.

Módis K, Gerő D, Stangl R, Rosero O, Szijártó A, Lotz G, Mohácsik P, Szoleczky P, Coletta C, Szabó C.

Int J Mol Med. 2013 Feb;31(2):437-46. doi: 10.3892/ijmm.2012.1203. Epub 2012 Dec 4.


Cell-based screening identifies paroxetine as an inhibitor of diabetic endothelial dysfunction.

Gerö D, Szoleczky P, Suzuki K, Módis K, Oláh G, Coletta C, Szabo C.

Diabetes. 2013 Mar;62(3):953-64. doi: 10.2337/db12-0789. Epub 2012 Dec 7.


Cellular bioenergetics is regulated by PARP1 under resting conditions and during oxidative stress.

Módis K, Gero D, Erdélyi K, Szoleczky P, DeWitt D, Szabo C.

Biochem Pharmacol. 2012 Mar 1;83(5):633-43. doi: 10.1016/j.bcp.2011.12.014. Epub 2011 Dec 16.


Identification of agents that reduce renal hypoxia-reoxygenation injury using cell-based screening: purine nucleosides are alternative energy sources in LLC-PK1 cells during hypoxia.

Szoleczky P, Módis K, Nagy N, Dóri Tóth Z, DeWitt D, Szabó C, Gero D.

Arch Biochem Biophys. 2012 Jan 1;517(1):53-70. doi: 10.1016/ Epub 2011 Nov 11.


Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function.

Suzuki K, Olah G, Modis K, Coletta C, Kulp G, Gerö D, Szoleczky P, Chang T, Zhou Z, Wu L, Wang R, Papapetropoulos A, Szabo C.

Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13829-34. doi: 10.1073/pnas.1105121108. Epub 2011 Aug 1.


Cytoprotective effects of adenosine and inosine in an in vitro model of acute tubular necrosis.

Módis K, Gero D, Nagy N, Szoleczky P, Tóth ZD, Szabó C.

Br J Pharmacol. 2009 Nov;158(6):1565-78. doi: 10.1111/j.1476-5381.2009.00432.x.


Oxidant-induced cardiomyocyte injury: identification of the cytoprotective effect of a dopamine 1 receptor agonist using a cell-based high-throughput assay.

Gerö D, Módis K, Nagy N, Szoleczky P, Tóth ZD, Dormán G, Szabó C.

Int J Mol Med. 2007 Nov;20(5):749-61.


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